scholarly journals Pentacyclic Triterpenoids from the Aerial Parts of Origanum Syriacum

2007 ◽  
Vol 2 (11) ◽  
pp. 1934578X0700201
Author(s):  
Iffat Mahmood ◽  
Faryal Vali Mohammad ◽  
Sadiqa Firdous ◽  
Viqar Uddin Ahmad
Keyword(s):  
Oleanolic Acid ◽  
Betulinic Acid ◽  
Spectroscopic Data ◽  
Pentacyclic Triterpenoids ◽  
Aerial Parts

From the aerial parts of Origanum syriacum a new lupane-type triterpenoid aldehyde has been isolated, together with betulinic acid, lupeol, and oleanolic acid. The new compound, origanal (1), was established as 3β-hydroxy-lup-20(29)-ene-30-al-28-oic acid from spectroscopic data.

scholarly journals Chemical Constituents of the Aerial Parts of Euphorbia Nematocypha

2016 ◽  
Vol 11 (2) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Chen Xu ◽  
Hai-Yang Jia ◽  
Bo Zuo ◽  
Zhi-Xin Liao ◽  
Lan-Ju Ji ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Ellagic Acid ◽  
Betulinic Acid ◽  
Methylene Chloride ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Cytotoxic Activities ◽  
Aerial Parts ◽  
Methylene Chloride Extract ◽  
Oleanane Triterpenoid

Chemical constituents of the dried aerial parts of Euphorbia nematocypha were investigated. A new oleanane triterpenoid, trans, trans-2′,4′-hexadienedioicacid-1′-β-amyrin ester (1), together with, β-amyrin (2), β-amyrin acetate (3), betulinic acid (4), ellagic acid (5), oleanolic acid (6), β-sitosterol (7), kaempferol (8), quercetin (9), lupeol (10) and pseudo-taraxasterol (11) were isolated from the methylene chloride extract. Their structures were elucidated on the basis of extensive spectroscopic (1D- & 2D-NMR) and ESI-MS analysis and comparison with data reported in the literature. The new isolated triterpenoid showed moderate cytotoxic activities against HeLa and MCF-7cell lines.

scholarly journals Analysis of Salvia Coccinea from Jamaican Populations

2009 ◽  
Vol 4 (6) ◽  
pp. 1934578X0900400
Author(s):  
Glenroy D. A. Martin ◽  
William F. Reynolds ◽  
Paul B. Reese
Keyword(s):  
Medicinal Plant ◽  
Betulinic Acid ◽  
Spectroscopic Data ◽  
First Report ◽  
Aerial Parts ◽  
Phytochemical Investigation ◽  
Steroid Precursor

This is the first report of a phytochemical investigation of Jamaican populations of a local folk medicinal plant Salvia coccinea (Lamiaceae/Labiatae). Apart from the presence of β-sitosterol, phytochemical profiling of the aerial parts yielded compounds other than those previously reported from Indian and Italian populations. The triterpenes betulinic acid and betulin, the phytosterols β-sitosterol and β-sitosterol-3- O-β-D-glucopyranoside, as well as the steroid precursor squalene were isolated. The structures of the compounds were established by comparison of NMR spectroscopic data with those reported in literature.

New Applications of Oleanolic Acid and its Derivatives as Cardioprotective Agents: A Review of their Therapeutic Perspectives

2019 ◽  
Vol 25 (35) ◽  
pp. 3740-3750 ◽  
Author(s):  
Ning Sun ◽  
Dongli Li ◽  
Xiaoqing Chen ◽  
Panpan Wu ◽  
Yu-Jing Lu ◽  
...  
Keyword(s):  
Oleanolic Acid ◽  
Liver Diseases ◽  
Therapeutic Agent ◽  
Heart Diseases ◽  
Pentacyclic Triterpenoids ◽  
Hepatic Drug ◽  
Approved Drugs ◽  
New Applications ◽  
Functional Mechanisms ◽  
Potent Therapeutic Agent

Oleanolic acid is an analogue of pentacyclic triterpenoids. It has been used as a hepatic drug for over 20 years in China. Currently, there are only five approved drugs derived from pentacyclic triterpenoids, including oleanolic acid (liver diseases), asiaticoside (wound healing), glycyrrhizinate (liver diseases), isoglycyrrhizinate (liver disease) and sodium aescinate (hydrocephalus). To understand more about the bioactivity and functional mechanisms of oleanolic acid, it can be developed as a potent therapeutic agent, in particular, for the prevention and treatment of heart diseases that are the leading cause of death for people worldwide. The primary aim of this mini-review is to summarize the new applications of oleanolic acid and its derivatives as cardioprotective agents reported in recent years and to highlight their therapeutic perspectives in cardiovascular diseases.

ChemInform Abstract: Two New Pentacyclic Triterpenoids from the Aerial Parts of Lantana camara Linn.

ChemInform ◽  
2010 ◽  
Vol 31 (26) ◽  
pp. no-no
Author(s):  
Bina S. Siddiqui ◽  
Aneela Wahab ◽  
Sabira Begum
Keyword(s):  
Lantana Camara ◽  
Pentacyclic Triterpenoids ◽  
Aerial Parts

Antidiabetic and Antioxidant Activities of Major Flavonoids of Cynanchum acutum L. (Asclepiadaceae) Growing in Egypt

2008 ◽  
Vol 63 (9-10) ◽  
pp. 658-662 ◽  
Author(s):  
Ghada A. Fawzy ◽  
Hossam M. Abdallah ◽  
Mohamed S. A. Marzouk ◽  
Fathy M. Soliman ◽  
Amany A. Sleem
Keyword(s):  
Blood Glucose ◽  
Spectroscopic Data ◽  
Methanolic Extract ◽  
Antioxidant Activities ◽  
First Report ◽  
Insulin Levels ◽  
Butanol Fraction ◽  
Aerial Parts ◽  
First Time

Seven flavonoids were isolated from the butanol fraction of the methanolic extract of the aerial parts of Cynanchum acutum L. (Asclepiadaceae). All of which have been isolated for the first time from the genus Cynanchum. Their structures were established as quercetin 3-O-β-galacturonopyranoside (1), quercetin 7-O-β-glucopyranoside (2), tamarixtin 3-O-β-galacturonopyranoside (3), kaempferol 3-O-β-galacturonopyranoside (4), 8-hydroxyquercetin 3-O-β-galactopyranoside (5), tamarixtin 3-O-α-rhamnopyranoside (6), and tamarixtin 7-O-α-arabinopyranoside (7) on the basis of their chromatographic properties, chemical and spectroscopic data. The major isolated flavonoids 1, 2 and 3 were found to exhibit significant antioxidant and antidiabetic activities (by measuring blood glucose and insulin levels). This is the first report about the antioxidant and antidiabetic activities of compounds 1 - 3.

Two New Cyclolignan Glycosides from Acanthus ilicifolius

2004 ◽  
Vol 59 (3) ◽  
pp. 341-344 ◽  
Author(s):  
Jun Wu ◽  
Si Zhang ◽  
Qingxin Li ◽  
Jianshe Huang ◽  
Zhihui Xiao ◽  
...  
Keyword(s):  
Spectroscopic Data ◽  
Structure Elucidation ◽  
Aerial Parts ◽  
Acanthus Ilicifolius

Two new cyclolignan glycosides, (+)-lyoniresinol 3a-O-α-D-galactopyranosyl-(1 → 6)-β -D-glucopyranoside (1) and (+)-lyoniresinol 2a-O-α-D-galactopyranosyl-3a-O-β -D-glucopyranoside (2) were isolated from the aerial parts of Acanthus ilicifolius. Their structure elucidation is based on the analyses of spectroscopic data

scholarly journals Extraction and Determinationof Chemical Structure from flower Dicholomethane Extract of Catharanthus roseus

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shahin Aziza ◽  
Koushik Sahab ◽  
Md. Abdus Satter Miac ◽  
Md. Hemayet Hossaina
Keyword(s):  
Data Analysis ◽  
Oleanolic Acid ◽  
Catharanthus Roseus ◽  
Spectroscopic Data ◽  
Chemical Structure

Catharanthus roseus is considered a cooling medicine. Two compounds: ?-sitosterol (1) and 3?-Hydroxy-lup-20 (29)-en-28-oic acid or Oleanolic acid (2) have been isolated from flowers from Dicholoromethane extract of Catharanthus roseus. By different spectroscopic data analysis the structures of the compounds have been established.

Sign in / Sign up

Export Citation Format

Share Document