scholarly journals Extraction and Determinationof Chemical Structure from flower Dicholomethane Extract of Catharanthus roseus

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shahin Aziza ◽  
Koushik Sahab ◽  
Md. Abdus Satter Miac ◽  
Md. Hemayet Hossaina
Keyword(s):  
Data Analysis ◽  
Oleanolic Acid ◽  
Catharanthus Roseus ◽  
Spectroscopic Data ◽  
Chemical Structure

Catharanthus roseus is considered a cooling medicine. Two compounds: ?-sitosterol (1) and 3?-Hydroxy-lup-20 (29)-en-28-oic acid or Oleanolic acid (2) have been isolated from flowers from Dicholoromethane extract of Catharanthus roseus. By different spectroscopic data analysis the structures of the compounds have been established.

scholarly journals Chemical constituents of Chaenomeles sinensis twigs and their biological activity

2020 ◽  
Vol 16 ◽  
pp. 3078-3085
Author(s):  
Joon Min Cha ◽  
Dong Hyun Kim ◽  
Lalita Subedi ◽  
Zahra Khan ◽  
Sang Un Choi ◽  
...  
Keyword(s):  
Biological Activity ◽  
Data Analysis ◽  
Cell Lines ◽  
Chemical Structure ◽  
Biological Effects ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Nmr Data ◽  
Chaenomeles Sinensis ◽  
Modified Mosher’S Method

A new megastigmane-type norsesquiterpenoid glycoside, chaemeloside (1), was isolated from the twigs of Chaenomeles sinensis together with 11 known phytochemicals through chromatographic methods. The chemical structure of the new isolate 1 was determined by conventional 1D and 2D NMR data analysis, ECD experiment, hydrolysis followed by a modified Mosher’s method, and LC–MS analysis. The characterized compounds’ biological effects including cytotoxicity against cancer cell lines, antineuroinflammatory activity, and potential neurotrophic effect were evaluated.

Predicting skin permeation rate from nuclear magnetic resonance spectra

2016 ◽  
Vol 18 (16) ◽  
pp. 4468-4474 ◽  
Author(s):  
Nan An ◽  
John-Hanson Machado ◽  
Yuechuan Tang ◽  
Jakub Kostal ◽  
Adelina Voutchkova-Kostal
Keyword(s):  
Molecular Weight ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spectroscopic Data ◽  
Chemical Structure ◽  
Skin Permeation ◽  
Permeation Rate ◽  
Organic Chemicals ◽  
Predictive Method ◽  
Nuclear Magnetic Resonance Spectra

A predictive method is reported for estimating skin permeation of organic chemicals exclusively from NMR spectroscopic data and molecular weight, which does not require knowledge of chemical structure.

scholarly journals The Isolation and Characterisation of Seco-phthalide Isoquinoline Alkaloid from Corydalis species

2013 ◽  
Vol 30 ◽  
pp. 165-167 ◽  
Author(s):  
Ram Narayan Jha
Keyword(s):  
Data Analysis ◽  
Spectroscopic Data ◽  
Methanolic Extract ◽  
Chemical Society ◽  
Isoquinoline Alkaloid ◽  
Whole Plant ◽  
Chromatographic Resolution

Chromatographic resolution of crude base fraction of the methanolic extract of the whole plant of Corydalis longipes on Silca-gel column yielded one Seco-phthalide isoquinoline alkaloid, N-methylhydrasteine hydroxyl lactam. Its structure was established on the basis of extensive spectroscopic data analysis and comparison with spectroscopic data reported.DOI: http://dx.doi.org/10.3126/jncs.v30i0.9389Journal of Nepal Chemical Society Vol. 30, 2012 Page:  165-167 Uploaded date: 12/20/2013   

scholarly journals Platelet Antiaggregating Activity and Chemical Constituents of Salvia x Jamensis J. Compton

2008 ◽  
Vol 3 (6) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Angela Bisio ◽  
Giovanni Romussi ◽  
Eleonora Russo ◽  
Nunziatina De Tommasi ◽  
Nicola Mascolo ◽  
...  
Keyword(s):  
Data Analysis ◽  
Platelet Aggregation ◽  
Ursolic Acid ◽  
Betulinic Acid ◽  
Spectroscopic Data ◽  
Chemical Constituents ◽  
Isopimaric Acid ◽  
Phytochemical Study ◽  
Rat Platelets ◽  
Significant Concentration

A phytochemical study has been carried out on the surface exudate of Salvia x jamensis, which showed a significant platelet antiaggregating activity. The known compounds isopimaric acid (2), 14-α-hydroxy-isopimaric acid (3), 3β-hydroxy-isopimaric acid (4), 7,8β-dihydrosalviacoccin (5), betulinic acid (6), and ursolic acid (7) were isolated together with the new diterpene 1. The structure of 1 was determined as 15,16-epoxy-cleroda-3-en-7α,10β-dihydroxy-12,17;19,18-diolide on the basis of spectroscopic data analysis. Among all tested compounds, 2 showed a significant concentration-dependent antiaggregating activity when ADP (3 μM) was used as agonist on rat platelets. Conversely, 1 increased ADP–induced platelet aggregation.

A feature-based soft sensor for spectroscopic data analysis

2019 ◽  
Vol 78 ◽  
pp. 98-107 ◽  
Author(s):  
Devarshi Shah ◽  
Jin Wang ◽  
Q. Peter He
Keyword(s):  
Data Analysis ◽  
Spectroscopic Data ◽  
Soft Sensor ◽  
Feature Based

scholarly journals Lampiran 1F Paper Single production of Kojic acid by Aspergillus flavus and the revision of flufuran

2021 ◽  
Author(s):  
Philiphi de Rozari
Keyword(s):  
Aspergillus Flavus ◽  
Endophytic Fungi ◽  
Catharanthus Roseus ◽  
Spectroscopic Data ◽  
Kojic Acid ◽  
Annona Squamosa ◽  
Nmr Data ◽  
Toxic Metabolites ◽  
Single Production ◽  
Industrial Use

Timor Island is very hot and dry due to the high intensity of sunlight experienced throughout the year. The endophytic fungi Aspergillus flavus had been isolated from medicinal plants such as Catharanthus roseus, Annona squamosa and Curcuma xanthorisa. The endophytic fungi A. flavus from each plant was cultivated on solid rice media and then analyzed for its capability for producing kojic acid. The production of kojic acid was analyzed by HPLC; the highest amount of kojic acid was observed from the endophytic fungi A. flavus, isolated from the stem of Catharanthus roseus, followed by A. flavus from Annona squamosa and Curcuma xanthorisa. Simple VLC fractionation of the extract of A. flavus from C.roseus led to the isolation of around 11.1 g of pure kojic acid. The structure of kojic acid (1) was confirmed by NMR and MS spectroscopic data. A comparison of the NMR data with the literature supported the revision of the natural product flufuran to kojic acid. To the best of our knowledge, this is the first report of a strain of endophytic fungi producing only kojic acid without any other toxic metabolites such as alfatoxins. Therefore, this Aspergillus flavus strain can be applied as a potential producer of kojic acid for industrial use.

Sign in / Sign up

Export Citation Format

Share Document