scholarly journals Bacilohydrin A, a New Cytotoxic Cyclic Lipopeptide of Surfactins Class Produced by Bacillus sp. SY27F from the Indian Ocean Hydrothermal Vent

2019 ◽  
Vol 14 (1) ◽  
pp. 1934578X1901400 ◽  
Author(s):  
Hong Zhou ◽  
Yu He ◽  
Yongqi Tian ◽  
Bailin Cong ◽  
Huanghao Yang
Keyword(s):  
Mass Spectrometry ◽  
Indian Ocean ◽  
Absolute Configuration ◽  
Hydrothermal Vent ◽  
Secondary Ion Mass Spectrometry ◽  
2D Nmr ◽  
Bacillus Sp ◽  
2D Nmr Spectroscopy ◽  
Cyclic Lipopeptide ◽  
The Indian Ocean

Bacilohydrin A, a new cyclic lipopeptide composed of seven mixed D/L-amino acids (L-Ile1—L-Leu2—D-Asp3—L-Val4—L-Leu5—L-Leu6—L-Gln7) and a ( R)-3-hydroxy-12-methyltetradecanoic acid (HMT) residue, was isolated from the crude culture extract of Bacillus sp. SY27F, which was obtained from the Indian Ocean hydrothermal vent. Its planar structure was elucidated by spectroscopic analyses, including 1D and 2D NMR spectroscopy, mass spectrometry (MS), and secondary ion mass spectrometry (MS/MS), whereas its absolute configuration was determined by modified Marfey's analysis. Bacilohydrin A displayed significant cytotoxicities against DU-145, MCF-7 and HepG2 cancer cell lines with IC50 values of 50.3-175.1 nM. Additionally, this is the first time to determine the absolute configuration of a D-aspartic acid residue in surfactin class.

scholarly journals Ambient-Temperature Synthesis of (E)-N-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-1-(pyridin-2-yl)methanimine

Molbank ◽  
10.3390/m1250 ◽  
2021 ◽  
Vol 2021 (3) ◽  
pp. M1250
Author(s):  
Diana Becerra ◽  
Justo Cobo ◽  
Juan-Carlos Castillo
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Ambient Temperature ◽  
Magnesium Sulfate ◽  
Elemental Analysis ◽  
Condensation Reaction ◽  
2D Nmr ◽  
2D Nmr Spectroscopy ◽  
Temperature Synthesis ◽  
Tert Butyl

We report the ambient-temperature synthesis of novel (E)-N-(3-(tert-butyl)-1-methyl-1H-pyrazol-5-yl)-1-(pyridin-2-yl)methanamine 3 in 81% yield by a condensation reaction between 3-(tert-butyl)-1-methyl-1H-pyrazol-5-amine 1 and 2-pyridinecarboxaldehyde 2 in methanol using magnesium sulfate as a drying agent. The N-pyrazolyl imine 3 was full characterized by IR, 1D, and 2D NMR spectroscopy, mass spectrometry, and elemental analysis.

scholarly journals Exploring the Phytochemicals of Acacia melanoxylon R. Br.

Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2698
Author(s):  
Diana Alves ◽  
Sidónio Duarte ◽  
Pedro Arsénio ◽  
Joana Gonçalves ◽  
Cecília M. P. Rodrigues ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Mass Spectrometry ◽  
Methyl Ester ◽  
Nmr Assignments ◽  
2D Nmr ◽  
Human Colorectal Cancer ◽  
2D Nmr Spectroscopy ◽  
Acacia Melanoxylon ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells

Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.

scholarly journals A new species of the genus Smacigastes Ivanenko & Defaye, 2004 (Tegastidae, Harpacticoida, Copepoda) from the Onnuri Vent Field in the Indian Ocean

2020 ◽  
Vol 96 (2) ◽  
pp. 699-714
Author(s):  
Jong Guk Kim ◽  
Jimin Lee
Keyword(s):  
New Species ◽  
Indian Ocean ◽  
Hydrothermal Vent ◽  
Hydrothermal Vents ◽  
First Record ◽  
Cold Seeps ◽  
Dichotomous Key ◽  
The Family ◽  
The Indian Ocean ◽  
A New Species

The genus Smacigastes Ivanenko & Defaye, 2004 (Harpacticoida, Copepoda) is the most primitive genus in the family Tegastidae Sars, 1904, occurring in deep-sea chemosynthetic environments, such as hydrothermal vents, cold seeps, whale falls and wood falls. Our exploration of the Onnuri Vent Field, the sixth active hydrothermal vent system in the Central Indian Ridge, resulted in the discovery of a new species in the genus Smacigastes. A detailed morphological analysis of S. pumilasp. nov. reveals that it most resembles S. barti Gollner, Ivanenko & Martínez Arbizu, 2008, described from a hydrothermal vent in the East Pacific Ridge; the new species can be distinguished from the existing species by the 8-segmented female antennule, the absence of an abexopodal seta on the antennary basis, the mandibular exopod represented by a single seta and the exopod of the first leg with five setae. This is the first record of Smacigastes in the Indian Ocean. A dichotomous key to species of the genus Smacigastes worldwide is provided.

Structural Studies of Chelirubine and Chelilutine Free Bases

1998 ◽  
Vol 63 (7) ◽  
pp. 1045-1055 ◽  
Author(s):  
Jiří Dostál ◽  
Jiří Slavík ◽  
Milan Potáček ◽  
Radek Marek ◽  
Otakar Humpa ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Quantum Chemical ◽  
2D Nmr ◽  
Molecular Symmetry ◽  
Structural Studies ◽  
Free Base ◽  
2D Nmr Spectroscopy ◽  
Sanguinaria Canadensis ◽  
First Time

The structures of chelirubine and chelilutine free bases have been examined by 2D NMR spectroscopy and mass spectrometry. Chelirubine chloride (1a) upon treatment with Na2CO3 yielded free base which possessed the constitution of bis(5,6-dihydrochelirubin-6-yl) ether (2a). The free base of chelilutine (1b) was determined to be bis(5,6-dihydrochelilutin-6-yl) ether (2b). The aqueous NH3 treatment of chelilutine (1b) produced bis(5,6-dihydrochelilutin-6-yl)amine (3b). 6-Hydroxy-5,6-dihydrochelirubine (4a) and 6-hydroxy-5,6-dihydrochelilutine (4b) were detected only in CDCl3 solution by NMR spectroscopy. In CDCl3, the compound 2b underwent hydrolysis to 4b that was immediately followed by the reverse condensation to a diastereomer of 2b. Pseudokinetics of this reaction was followed by NMR spectroscopy and quantum chemical calculations were carried out to support the suggested type of molecular symmetry alteration. The known alkaloid dihydrochelirubine (5) was isolated for the first time from Sanguinaria canadensis.

scholarly journals Description of Barathricola thermophilus, a new species from a deep-sea hydrothermal vent field in the Indian Ocean with redescription of the Barathricola type species (Crustacea, Copepoda, Cyclopoida)

ZooKeys ◽  
2019 ◽  
Vol 865 ◽  
pp. 103-121 ◽  
Author(s):  
Viatcheslav N. Ivanenko ◽  
Jimin Lee ◽  
Cheon Young Chang ◽  
Il-Hoi Kim
Keyword(s):  
New Species ◽  
Indian Ocean ◽  
Deep Sea ◽  
Hydrothermal Vent ◽  
Type Species ◽  
Central Ridge ◽  
The Indian Ocean ◽  
Morphological Differences ◽  
Hydrothermal Vent Field ◽  
Copepoda Cyclopoida

Re-study of the type species of the genus Barathricola Humes, 1999 (Copepoda, Cyclopoida, Schminkepinellidae) described from the Pacific Ocean (Juan de Fuca Ridge), and study of the species Barathricolathermophilussp. nov. from a deep-sea hydrothermal vent field on the Central Ridge in the Indian Ocean revealed a derived feature and widespread geographic distribution of this deep-sea genus of cyclopoids. The derived feature of Barathricola is the sexually dimorphic third endopodal segment of leg 3 possessing a small outer terminal spine together with spine-like outgrowths on this segment. The new species differs from Barathricolarimensis Humes, 1999 in not expressing sexual dimorphism in leg 5, having three spines and one seta on its exopod in both sexes (B.rimensis has three spines and one seta on the female exopod but three spines and two setae on the male exopod) and in having broader caudal rami which are 8.9 times longer than wide in the female (this ratio for B.rimensis is 11). An amended diagnosis of the genus Barathricola, a key and a table of morphological differences for all species of Schminkepinellidae are given.

scholarly journals 2-Oxo-2H-chromen-7-yl 4-chlorobenzoate

Molbank ◽  
10.3390/m1279 ◽  
2021 ◽  
Vol 2021 (3) ◽  
pp. M1279
Author(s):  
Diana Becerra ◽  
Jaime Portilla ◽  
Juan-Carlos Castillo
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
2D Nmr ◽  
Acylation Reaction ◽  
2D Nmr Spectroscopy ◽  
Slight Excess

We describe the synthesis of 2-oxo-2H-chromen-7-yl 4-chlorobenzoate 3 in 88% yield by the O-acylation reaction of 7-hydroxy-2H-chromen-2-one 1 with 4-chlorobenzoyl chloride 2 in dichloromethane using a slight excess of triethylamine at 20 °C for 1 h. The ester 3 was completely characterized by mass spectrometry, IR, UV–Vis, 1D, and 2D NMR spectroscopy.

scholarly journals A New Glucuronolactone Glycoside Phoenixoside B from the Seeds of Phoenix Dactylifera

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800
Author(s):  
Sumbul Azmat ◽  
Rehana Ifzal ◽  
Faryal Vali Mohammad ◽  
Viqar Uddin Ahmad ◽  
Aqib Zahoor
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Soluble Fraction ◽  
2D Nmr ◽  
Phoenix Dactylifera ◽  
2D Nmr Spectroscopy ◽  
High Resolution Mass ◽  
Resolution Mass

A new glucuronolactone glycoside, phoenixoside B (1), has been isolated from the n-butanol soluble fraction of seeds of Phoenix dactylifera. The structure was characterized as 1-(1-ethyl-β-D-glucosyl)-4,5-diethyl-[α-D-glucofuranourono-6,3-lactone] on the basis of 1D and 2D-NMR spectroscopy and high-resolution mass spectrometry.

scholarly journals Struthiolanone: A Flavanone-Resveratrol Adduct from Struthiola Argentea

2008 ◽  
Vol 3 (2) ◽  
pp. 1934578X0800300
Author(s):  
Sloan Ayers ◽  
Deborah L. Zink ◽  
Robert Brand ◽  
Seef Pretorius ◽  
Dennis Stevenson ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Absolute Configuration ◽  
High Resolution Mass Spectrometry ◽  
2D Nmr ◽  
Spectroscopic Techniques ◽  
Cd Spectrum ◽  
High Resolution Mass ◽  
The Absolute ◽  
Resolution Mass

Struthiolanone (1), a flavanone-resveratrol adduct, was isolated from Struthiola argentea. Its structure was determined by high-resolution mass spectrometry and 1D- and 2D-NMR spectroscopic techniques. The absolute configuration was determined by comparison of the CD spectrum of biflavonoids. This compound appears to be the first example of a flavanoid-stilbene adduct.

scholarly journals Marine Reservoir Correction for the Cocos (Keeling) Islands, Indian Ocean

Radiocarbon ◽  
2004 ◽  
Vol 46 (2) ◽  
pp. 603-610 ◽  
Author(s):  
Quan Hua ◽  
Colin D Woodroffe ◽  
Mike Barbetti ◽  
Scott G Smithers ◽  
Ugo Zoppi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Indian Ocean ◽  
Red Sea ◽  
Surface Waters ◽  
Accelerator Mass Spectrometry ◽  
Arabian Sea ◽  
Indonesian Throughflow ◽  
Gulf Of Aden ◽  
The Indian Ocean ◽  
Reservoir Age

Known-age corals from the Cocos (Keeling) Islands, Indian Ocean, have been analyzed by accelerator mass spectrometry (AMS) for radiocarbon to determine marine reservoir age corrections. The ΔR value for the Cocos (Keeling) Islands is 66 ± 12 yr based on the analyses undertaken for this study. When our AMS and previously published dates for Cocos are averaged, they yield a ΔR of 64 ± 15 yr. This is a significant revision of an earlier estimate of the ΔR value for the Cocos (Keeling) Islands of 186 ± 66 yr (Toggweiler et al. 1991). The (revised) lower ΔR for the Cocos (Keeling) Islands is consistent with GEOSECS 14C data for the Indian Ocean, and previously published bomb 14C data for the Red Sea, Gulf of Aden, and Cocos Islands. The revised ΔR is also close to values for the eastern Indian Ocean and adjacent seas. These suggest surface waters that reach the Cocos Islands might be partly derived from the far western Pacific, via the Indonesian throughflow, and might not be influenced by the southeast flow from the Arabian Sea.

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