Trends in cardiovascular diseases burden and vascular risk factors in Italy: The Global Burden of Disease study 1990–2017

2020 ◽  
pp. 204748732094941
Author(s):  
Paolo A Cortesi ◽  
Carla Fornari ◽  
Fabiana Madotto ◽  
Sara Conti ◽  
Mohsen Naghavi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Disease Burden ◽  
European Countries ◽  
Vascular Risk ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study

Aims An exhaustive and updated estimation of cardiovascular disease burden and vascular risk factors is still lacking in European countries. This study aims to fill this gap assessing the global Italian cardiovascular disease burden and its changes from 1990 to 2017 and comparing the Italian situation with European countries. Methods All accessible data sources from the 2017 Global Burden of Disease study were used to estimate the cardiovascular disease prevalence, mortality and disability-adjusted life years and cardiovascular disease attributable risk factors burden in Italy from 1990 to 2017. Furthermore, we compared the cardiovascular disease burden within the 28 European Union countries. Results Since 1990, we observed a significant decrease of cardiovascular disease burden, particularly in the age-standardised prevalence (–12.7%), mortality rate (–53.8%), and disability-adjusted life years rate (–55.5%). Similar improvements were observed in the majority of European countries. However, we found an increase in all-ages prevalence of cardiovascular diseases from 5.75 m to 7.49 m Italian residents. Cardiovascular diseases still remain the first cause of death (34.8% of total mortality). More than 80% of the cardiovascular disease burden could be attributed to known modifiable risk factors such as high systolic blood pressure, dietary risks, high low density lipoprotein cholesterol, and impaired kidney function. Conclusions Our study shows a decline in cardiovascular mortality and disability-adjusted life years, which reflects the success in reducing disability, premature death and early incidence of cardiovascular diseases. However, the burden of cardiovascular diseases is still high. An approach that includes the cooperation and coordination of all stakeholders of the Italian National Health System is required to further reduce this burden.

scholarly journals Global, Regional, and National Death, and Disability-Adjusted Life-Years (DALYs) for Cardiovascular Disease in 2017 and Trends and Risk Analysis From 1990 to 2017 Using the Global Burden of Disease Study and Implications for Prevention

2021 ◽  
Vol 9 ◽  
Author(s):  
Zhiyong Li ◽  
Longfei Lin ◽  
Hongwei Wu ◽  
Lei Yan ◽  
Huanhuan Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Heart Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
The World ◽  
Disease Study ◽  
Cvd Mortality

Background: Cardiovascular disease is the leading cause of death worldwide and a major barrier to sustainable human development. The objective of this study was to evaluate the global, sex, age, region, and country-related cardiovascular disease (CVD) burden, as well as the trends, risk factors, and implications for the prevention of CVD.Methods: Detailed information from 1990 to 2017, including global, regional, and national rates of CVD, and 11 categories of mortality and disability-adjusted life years (DALYs) were collected from the Global Burden of Disease Study 2017. The time-dependent change in the trends of CVD burdens was evaluated by annual percentage change.Results: More than 17 million people died from CVD in 2017, which was approximately two times as many as cancer, and increased nearly 50% compared with 1990. Ischemic heart disease and stroke accounted for 85% of the total age-standardized death rate (ASDR) of CVD. The ASDR and age-standardized DALYs rate (ASYR) of CVD were 1.5 times greater in men compared with women. People over the age of 50 were especially at risk for developing CVD, with the number of cases and deaths in this age group accounting for more than 90% of all age groups. CVD mortality was related to regional economic development and the social demographic index. In regions with a high economic income or socio-demographic index, there was a greater decline in the ASDR of CVD. The ASDR of CVD in high SDI regions decreased more than 50% from 1990 to 2017. Tobacco use, diets low in whole grains, diets high in sodium, and high systolic blood pressure were the important risk factors related to CVD mortality.Conclusions: CVD remains a major cause of death and chronic disability in all regions of the world. Ischemic heart disease and stroke account for the majority of deaths related to CVD. Although the mortality rate for CVD has declined in recent years from a global perspective, the results of CVD data in 2017 suggest that the mortality and DALYs of CVD varied in different ages, sexes, and countries/regions around the world. Therefore, it is necessary to elucidate the specific characteristics of global CVD burden and establish more effective and targeted prevention strategies.

scholarly journals Risk of acute respiratory infection from crop burning in India: estimating disease burden and economic welfare from satellite and national health survey data for 250 000 persons

2019 ◽  
Vol 48 (4) ◽  
pp. 1113-1124 ◽  
Author(s):  
Suman Chakrabarti ◽  
Mohammed Tajuddin Khan ◽  
Avinash Kishore ◽  
Devesh Roy ◽  
Samuel P Scott
Keyword(s):  
Risk Factors ◽  
Respiratory Infection ◽  
Health Survey ◽  
Acute Respiratory Infection ◽  
Disease Burden ◽  
Crop Residue ◽  
Agricultural Crop ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years

Abstract Background Respiratory infections are among the leading causes of death and disability globally. Respirable aerosol particles released by agricultural crop-residue burning (ACRB), practised by farmers in all global regions, are potentially harmful to human health. Our objective was to estimate the health and economic costs of ACRB in northern India. Methods The primary outcome was acute respiratory infection (ARI) from India’s fourth District Level Health Survey (DLHS-4). DLHS-4 data were merged with Moderate-Resolution Imaging Spectroradiometer satellite data on fire occurrence. Mutually adjusted generalized linear models were used to generate risk ratios for risk factors of ARI. Overall disease burden due to ACRB was estimated in terms of disability-adjusted life years. Results Seeking medical treatment for ARI in the previous 2 weeks was reported by 5050 (2%) of 252 539 persons. Living in a district with intense ACRB—the top quintile of fires per day—was associated with a 3-fold higher risk of ARI (mutually adjusted risk ratio 2.99, 95% confidence interval 2.77 to 3.23) after adjustment for socio-demographic and household factors. Children under 5 years of age were particularly susceptible (3.65, 3.06 to 4.34 in this subgroup). Additional ARI risk factors included motor-vehicle congestion (1.96, 1.72 to 2.23), open drainage (1.91, 1.73 to 2.11), cooking with biomass (1.73, 1.58 to 1.90) and living in urban areas (1.35, 1.26 to 1.44). Eliminating ACRB would avert 14.9 million disability-adjusted life years lost per year, valued at US$152.9 billion over 5 years. Conclusions Investments to stop crop burning and offer farmers alternative crop-residue disposal solutions are likely to improve population-level respiratory health and yield major economic returns.

scholarly journals Systematic Analysis of the Global, Regional and National Burden of Cardiovascular Diseases from 1990 to 2017

2021 ◽  
Author(s):  
Zhenkun Wang ◽  
Aihua Du ◽  
Hong Liu ◽  
Ziwei Wang ◽  
Jifa Hu
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Mortality Rate ◽  
Systematic Analysis ◽  
Disability Adjusted Life ◽  
Life Years ◽  
National Burden ◽  
Comparative Risk ◽  
Disease Study ◽  
Standardized Mortality Rate

Abstract Background Previous studies on the burden of cardiovascular diseases (CVDs) were mainly based on limited data of the study period or area, or did not include detailed risk factor analysis. Objective To investigate up-to-date temporal and regional trends and risk factors of mortality and disability-adjusted life years (DALYs) attributed to CVDs by age, sex, and disease throughout the world. Methods Data for the disease burden of CVDs in 195 countries and territories from 1990 to 2017, including mortality, DALYs, age-standardized mortality rates, and age-standardized DALY rates, were estimated from the Global Burden of Disease Study 2017. Risk factors attributable to deaths and DALYs for CVDs were also estimated using the comparative risk assessment framework. Results The number of deaths from CVDs increased by 48.62%, from 11.94 (95% UI 11.78–12.18) million in 1990 to 17.79 (17.53–18.04) million in 2017. However, the age-standardized mortality rate decreased by an average of − 1.45% (− 1.72% to − 1.18%) annually. After fluctuation in the expected age-standardized mortality rate of CVDs in most of the socio-demographic index (SDI) scale, these rates decrease rapidly for SDI values of 0.7 and higher. In 2017, metabolic risks accounted for 73.48% of deaths and 73.25% of DALYs due to CVDs, behavioral factors accounted for 63.23% of deaths and 66.71% of attributable DALYs. Conclusion CVDs remain a major global health burden due to the increment in death numbers and DALYs. Aging and the main risk factors are the main drivers of mortality and health loss. More attention to main risk factors should be paid with supportive health policies.

scholarly journals Mapping the Trends in Esophageal Cancer Disease Burden in the United States: Results from the Global Burden of Disease Study 2017

2021 ◽  
Author(s):  
Di Lu ◽  
jianxue Zhai ◽  
Jintao Zhan ◽  
Xiguang Liu ◽  
Xiaoying Dong ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Burden Of Disease ◽  
Disease Burden ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Cancer Disease ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study ◽  
High Bmi

Abstract Background: Esophageal cancer is the 10th leading cancer in US but given limited research attention. This study aimed to investigate the esophageal cancer disease burden more comprehensively in US. Methods: Having retrieved states-categorized data on esophageal cancer incidence, mortality and disability-adjusted life years from the Global Burden of Disease study online resource, the current trends on esophageal cancer disease burden attributed to different risk factors and their relationship with economic status were analyzed using age-standardized rate and the estimated annual percentage change.Results: In US, the esophageal cancer age-standardized rate of incidence has been stable but age-standardized rates of mortality and disability-adjusted life years trended to decreased with estimated annual percentage changes of -0.237% and -0.471% from 1990 to 2017. Age-standardized rate of incidence was higher in males than in females, but both didn’t increase, so as age-standardized rates of mortality and disability-adjusted life years. The largest increase in age-standardized rates of incidence, mortality and disability-adjusted life years was observed in Oklahoma, whereas the largest decrease was seen in the District of Columbia. Age-standardized rates of mortality and disability-adjusted life years contributed to high BMI or diet low in fruits were growing. per capita disposable personal income trended to negatively correlated with estimated annual percentage changes of incidence, mortality and disability-adjusted life years.Conclusions: The esophageal cancer disease burden in US decreased from 1990 to 2017 but was heavier in males than in females, and increased in economically weaker states and populations with high BMI and low-fruit diet.

scholarly journals Disease Burden and Attributable Risk Factors of Ovarian Cancer From 1990 to 2017: Findings From the Global Burden of Disease Study 2017

2021 ◽  
Vol 9 ◽  
Author(s):  
Zhangjian Zhou ◽  
Xuan Wang ◽  
Xueting Ren ◽  
Linghui Zhou ◽  
Nan Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ovarian Cancer ◽  
Data Exchange ◽  
Disease Burden ◽  
Temporal Trends ◽  
High Body Mass Index ◽  
Disability Adjusted Life Years ◽  
Cancer Data ◽  
Disability Adjusted Life ◽  
Life Years

Aim: We aimed to estimate the disease burden and risk factors attributable to ovarian cancer, and epidemiological trends at global, regional, and national levels.Methods: We described ovarian cancer data on incidence, mortality, and disability-adjusted life-years as well as age-standardized rates from 1990 to 2017 from the Global Health Data Exchange database. We also estimated the risk factors attributable to ovarian cancer deaths and disability-adjusted life-years. Measures were stratified by region, country, age, and socio-demographic index. The estimated annual percentage changes and age-standardized rates were calculated to evaluate temporal trends.Results: Globally, ovarian cancer incident, death cases, and disability-adjusted life-years increased by 88.01, 84.20, and 78.00%, respectively. However, all the corresponding age-standardized rates showed downward trends with an estimated annual percentage change of −0.10 (−0.03 to 0.16), −0.33 (−0.38 to −0.27), and −0.38 (−0.32 to 0.25), respectively. South and East Asia and Western Europe carried the heaviest disease burden. The highest incidence, deaths, and disability-adjusted life-years were mainly in people aged 50–69 years from 1990 to 2017. High fasting plasma glucose level was the greatest contributor in age-standardized disability-adjusted life-years rate globally as well as in all socio-demographic index quintiles and most Global Disease Burden regions. Other important factors were high body mass index and occupational exposure to asbestos.Conclusion: Our study provides valuable information on patterns and trends of disease burden and risk factors attributable to ovarian cancer across age, socio-demographic index, region, and country, which may help improve the rational allocation of health resources as well as inform health policies.

Sign in / Sign up

Export Citation Format

Share Document