scholarly journals Hereditary geniospasm in a mother and son treated with botulinum toxin injection: A case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2199359
Author(s):  
Clare Perkins ◽  
Wei Jia ◽  
James Rainsbury ◽  
Andrew Lux

Hereditary geniospasm is a rare and benign disorder that can cause distress and social embarrassment to patients. There are only a handful of possible treatment options available. Due to the rarity of the condition, practices differ across the world and the results are varied. These include beta-blockers, benzodiazepines and anti-epileptics. These treatments can have significant side-effects when used long term. However, botulinum toxin injections have been successfully used in a handful of cases. We report a successful botulinum treatment of hereditary geniospasm in a mother and son, with the injection protocols.

2012 ◽  
Vol 126 (3) ◽  
pp. 328-330 ◽  
Author(s):  
J van Griethuysen ◽  
C Al Yaghchi ◽  
G Sandhu

AbstractObjective:We report a novel bilateral suture lateralisation technique that allowed permanent tracheostomy decannulation in a patient with severe paradoxical vocal fold movement.Case report:A 45-year-old woman presented to the accident and emergency department with worsening shortness of breath. Flexible nasoendoscopy revealed limited vocal fold abduction and an emergency tracheostomy was sited; this was subsequently changed to a long-term Silver Negus tube. Her tracheostomy care was complicated by discomfort and dislodgement. The diagnosis of paradoxical vocal fold movement was only made when the patient presented to our department. Cognitive behaviour therapy and botulinum toxin injection were tried without success. A right vocal fold lateralisation procedure was performed, which enabled temporary tracheostomy decannulation. A left vocal fold lateralisation procedure was subsequently performed and the patient was successfully decannulated, with significant improvement in quality of life.Conclusion:Paradoxical vocal fold movement is a rare condition that is most commonly managed by biofeedback sessions, relaxation manoeuvres or botulinum toxin injection. However, in cases similar to ours in which these treatments are unsuccessful, we suggest a ‘last resort’ technique to manage this rare condition.


Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
pp. 7418 ◽  
Author(s):  
Panagiotis Katsinelos ◽  
Grigoris Chatzimavroudis ◽  
Kostas Fasoulas ◽  
Ioannis Pilpilidis ◽  
Georgia Lazaraki ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. 133-136
Author(s):  
Courtney Gilbert ◽  
Michelle Sauer ◽  
JenFu Cheng

Lesch-Nyhan syndrome is a genetic metabolic disorder often involving dystonia and self-mutilating behavior. This case report describes a 13-year-old boy with Lesch-Nyhan syndrome and self-mutilating behavior who received botulinum toxin injections to his bilateral masseter muscles after failing multiple other treatments. Following injections, the patient had reduction in self-biting, along with improvements in speech, mastication and feeding observed in speech therapy. Botulinum toxin injections to the masseters may help to improve oromotor function and reduce self-mutilating behaviors in children with Lesch-Nyhan syndrome who have failed more conservative treatments, providing opportunity for improved functional status and patient safety. Further investigation is indicated to establish optimal dosing. Additionally, the mechanism for the reduction of self-mutilating behavior is unclear and justifies additional investigation.


2017 ◽  
Vol 5 (1) ◽  
pp. 41
Author(s):  
Bhuwan Raj Pandey ◽  
Anup Acharya ◽  
Madan Mohan Singh

Introduction: Palatal myoclonus is a rare condition presenting with clicking sound in ear or muscle tremor in pharynx. There are two varieties: essential and symptomatic. Various treatment options exists ranging from watchful observation to botulinum toxin injection. We have not found any reported case of palatal myoclonus from our country. Here we present a case of essential palatal myoclonus managed with clonazepam. Case report: A young female presented in Ear Nose and Throat clinic with complain of auditory click and spontaneous rhythmic movement of throat muscles for eight months. On examination, there was involuntary, rhythmic contraction of bilateral soft-palate, uvula, and base of tongue. Neurological, eye, and peripheral examination were normal. A diagnosis of essential palatal myoclonus was made. It was managed successfully with clonazepam; patient was still on low dose clonazepam at the time of making this report. Conclusion: Essential palatal myoclonus can be clinically diagnosed and managed even in settings where MRI is not available or affordable.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Buket Tuğan Yıldız ◽  
Deniz Tuncel Berktaş

AbstractBackground and objectivesBotulinum toxin injection has been used for many years for various indications such as cervical dystonia, blepharospasm, oromandibular dystonia, hemifacial spasm in neurology. Botulinum toxin injections have been made in our clinic for about ten years. We want to report our experiences about botulinum toxin treatment in neurologic disease.MethodsIn this study, the data of the patients receiving BoNT injection between January 2018 and December 2019 was retrospectively analyzed. Age, gender, botulinum toxin indications, and mean dose, duration of efficacy, side effects noted for each injection were recorded.ResultsThere were 122 patients who received botulinum toxin injections between January 2018 and December 2019. Of the 122 patients identified, 28 had cervical dystonia, 61 had HFS, 21 had blepharospasm, 4 had generalized dystonia, 1 had hemidystonia following thalamic bleeding, 1 had tardive dystonia, 4 had migraine, 1 had bruxism and 1 had both migraine and bruxism.ConclusionBoNT injection is a treatment that has been used for various indications in neurology for almost 40 years. Side effects are limited and temporary with appropriate injections. We also had a wide range of indication profiles and high numbers of patients to whom we administered the BoNT treatment.


2010 ◽  
Vol 28 (2) ◽  
pp. 94-96 ◽  
Author(s):  
Ravindran Deepak ◽  
Hans Mathew ◽  
Mathew Koshy

This case describes the successful addition of acupuncture to treat a patient with cervical dystonia previously managed with Botox (botulinum toxin) injections. This resulted in reduced pain and muscle spasm relief and to the authors’ knowledge is the first case to be reported using this treatment combination. The patient was diagnosed with the idiopathic variant of cervical dystonia and had been treated with regular Botox injections for almost a year and half. She was then referred for a course of acupuncture to manage pain and reduce excessive muscle tone. She had excellent benefit from the acupuncture and she continued to get top-ups of acupuncture every 8–10 weeks. Requirement for Botox injections had decreased thus reducing its long-term side effects.


2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Min Woo Kim ◽  
Sihyeok Jang ◽  
Hyun-sun Yoon ◽  
Soyun Cho ◽  
Hyun-sun Park

<p>Botulinum toxin blocks the release of the neurotransmitter acetylcholine and helps to treat wrinkles. The efficacy and safety of botulinum toxin injection for upper facial wrinkles were established in several previous studies. Common side effects include transient headache, bruising, eyebrow ptosis and eyelid swelling. No adverse life threatening events or long-term complications have been reported. However, there have been a few reports on site-specific side effects, except for eyebrow ptosis or eyelid swelling. Two previous cases showing exaggerated glabellar wrinkles after botulinum toxin injection for forehead horizontal lines reported that no specific treatment for the exaggeration of wrinkles were done and it was left to slowly recede. In the present report, we highlighted a patient, whose significant glabellar protrusion was rapidly and effectively corrected with the use of botulinum toxin injection.</p>


2019 ◽  
Author(s):  
BA Högerle ◽  
EL Bulut ◽  
L Klotz ◽  
F Eichhorn ◽  
M Eichhorn ◽  
...  

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