scholarly journals Successful treatment of multifocal pedal Prototheca wickerhamii infection in a feline immunodeficiency virus-positive cat with multiple Bowenoid in situ carcinomas containing papillomaviral DNA sequences

2017 ◽  
Vol 3 (1) ◽  
pp. 205511691668859 ◽  
Author(s):  
Allan E Kessell ◽  
Derek McNair ◽  
John S Munday ◽  
Richard Savory ◽  
Catriona Halliday ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Feline Immunodeficiency Virus ◽  
Skin Lesions ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
First Case ◽  
Immunodeficiency Virus ◽  
Prototheca Wickerhamii

Case summary A 16-year-old, castrated male, feline immunodeficiency virus (FIV)-positive, domestic shorthair cat developed multiple skin lesions. Most of these were Bowenoid carcinoma in situ and contained DNA sequences consistent with Felis catus papillomavirus type 2. Two additional lesions that developed in the skin and subcutaneous tissues between the digital and carpal pads on the left forelimb and right hindlimb were shown by cytology, histology and culture to be caused by Prototheca wickerhamii. These lesions failed to improve in response to systemic therapy treatment with itraconazole, but excision by sharp en bloc resection with follow-up oral itraconazole therapy proved curative for one lesion, although the other lesion recurred, necessitating a second surgery. Relevance and novel information This is only the second reported case of feline protothecosis from Australia and the first case that has been cultured and identified to the species level. Also of great interest was the presence of multiple papillomavirus-associated neoplastic lesions, which may have afforded a portal of entry for the algal pathogen and the cat’s positive FIV status; the latter might have impacted on both viral and algal pathogenesis by effects on immunocompetence.

Pediatric Malignant Glomus Tumor of the Cervical Paraspinal Tissue: Case Report and Review of the Literature

2020 ◽  
Author(s):  
Andrea Ziegler ◽  
Eric Thorpe
Keyword(s):  
Glomus Tumor ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
The Body ◽  
Long Term Outcomes ◽  
Mesenchymal Tumors ◽  
En Bloc ◽  
Glomus Tumors ◽  
First Case

AbstractGlomus tumors are mesenchymal tumors that arise from glomus bodies and most frequently occur in the distal extremities. These tumors can occur throughout the body and are typically benign. However, a very small fraction of glomus tumors displays aggressive features and are considered atypical or malignant. We report on our experience and management of the first case in the literature of a malignant glomus tumor in a child originating in the paraspinal region with involvement of the cervical spine. Malignant glomus tumors tend to be locally aggressive, and en bloc resection is difficult, especially when the tumors occur in the head and neck. Additional studies on disease progression and adjuvant treatment outcomes are necessary to determine the best treatment approach and long-term outcomes in patients with malignant glomus tumors.

scholarly journals Primary Leiomyosarcoma of the Lumbar Spine: A Case Report and Literature Review

2021 ◽  
pp. 1-6
Author(s):  
Eric Luis ◽  
Eric Luis ◽  
Vasanthie Balakrishnan ◽  
Zainur Anuar bin Kamarul Bahrin ◽  
Han Sim Lim ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Literature Review ◽  
Immunohistochemical Staining ◽  
Tumor Recurrence ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
First Case ◽  
Staining Techniques

Primary vertebral leiomyosarcoma of the spine is extremely rare. Due to its rarity, the number of studies on pathology, treatment and prognosis is limited. Tissue Biopsy and Immunohistochemical staining techniques provide unequivocal diagnosis of leiomyosarcoma. The mainstay of treatment of spinal leiomyosarcoma is surgery, with or without radiotherapy and embolization. The principles of surgery comprise resection of tumor, decompression and stabilisation of the spinal cord and prevention of tumor recurrence. The Tomita total en-bloc resection is the preferred surgical technique. We hereby present a literature review of spinal leiomyosarcoma and a case report of the first case of a 56-year-old lady in Malaysia who was diagnosed with L3 vertebral leiomyosarcoma and lung metastasis.

scholarly journals Parathyromatosis: a very rare cause of recurrent primary hyperparathyroidism – case report and review of the literature

2019 ◽  
Vol 101 (8) ◽  
pp. e178-e183 ◽  
Author(s):  
M Haciyanli ◽  
S Karaisli ◽  
S Gucek Haciyanli ◽  
A Atasever ◽  
D Arikan Etit ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Subcutaneous Tissue ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Pathological Examination ◽  
Rare Entity ◽  
Review Of The Literature ◽  
En Bloc ◽  
First Case ◽  
History Of

Parathyromatosis is a rare entity and usually appears as a consequence of the seeding on previous parathyroid surgery which was applied for the secondary hyperparathyroidism. A 63-year-old woman presented with a history of subtotal thyroidectomy 20 years ago and parathyroidectomy due to primary hyperparathyroidism (PHPT) four years ago. Imaging methods revealed multiple parathyromatosis foci on subcutaneous tissue of the neck. En-bloc resection was performed and pathological examination confirmed the diagnosis of parathyromatosis. After an uneventful 10 months, biochemical and radiological tests revealed recurrence on bilateral thyroid lodges. En-bloc resection was performed. The patient has remained well for 24 months after the second operation and has been followed-up with normal parathormone and serum calcium values. To the best of our knowledge, this report describes the twenty-first case of parathyromatosis in PHPT setting in the literature. It should be kept in mind that parathyromatosis may recur at different sites in the neck even in patients with PHPT.

scholarly journals Safe Transanal Tumor Resection Using a Harmonic Scalpel

2014 ◽  
Vol 99 (1) ◽  
pp. 17-22
Author(s):  
Yuji Inoue ◽  
Takeshi Ohki ◽  
Ryousuke Nakagawa ◽  
Masakazu Yamamoto
Keyword(s):  
Harmonic Scalpel ◽  
Hyperplastic Polyp ◽  
Tumor Resection ◽  
Muscularis Propria ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Intraoperative Bleeding ◽  
Submucosal Invasive Cancer

Abstract We performed a safe and simple transanal tumor resection involving total layer resection using a harmonic scalpel as a resecting device. Here we report the results of our experience with this technique between 2005 and 2011. This study involved 32 patients who underwent transanal tumor resection using a harmonic scalpel. The subjects comprised 18 men and 14 women ranging in age from 34 to 87 years (mean: 64.5 years). The tumors measured 8 to 70 mm (mean: 31 mm) in diameter. The operation took 7 to 86 minutes (mean: 29 minutes), and the amount of bleeding was 0 to 165 mL (mean: 16.2 mL). There was no intraoperative blood loss that necessitated hemostatic procedures. Histopathologically, the lesions included hyperplastic polyp in 1 case, adenoma in 9, carcinoma in situ in 7, submucosal invasive cancer in 6, muscularis propria cancer in 4, carcinoid in 1, malignant lymphoma in 1, gastrointestinal stromal tumor in 1, mucosal prolapsed syndrome in 1, and mucosa-associated lymphoid tissue lymphoma in 1. With our technique, en bloc resection was achieved in all patients, and the use of a harmonic scalpel enabled us to complete the operation within 30 minutes, on average, without intraoperative bleeding.

En bloc resection of a pheochromocytoma metastatic to the spine for local tumor control and for treatment of chronic catecholamine release and related hypertension

2013 ◽  
Vol 18 (6) ◽  
pp. 611-616 ◽  
Author(s):  
Paul E. Kaloostian ◽  
Patricia L. Zadnik ◽  
Ahmed J. Awad ◽  
Edward McCarthy ◽  
Jean-Paul Wolinsky ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Vertebral Body ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Adrenergic Blockade ◽  
Angiographic Embolization ◽  
En Bloc ◽  
First Case

Resection of metastatic pheochromocytomas may be complicated by transient postoperative neurological deficits due to hypotension. The authors report the first case of en bloc excision of a spinal pheochromocytoma with associated long-term hypertensive management off all medication. Interestingly, this is the first case of transient hypotension following en bloc resection of pheochromocytoma associated with temporary hypotension-associated neurological decline that resolved completely after correction of hypotension postoperatively. A 23-year-old man with a prior adrenalectomy for pheochromocytoma presented with focal thoracic pain. He had a known T-10 vertebral body lesion for which he received chemotherapy and radiation therapy. Imaging demonstrated increased destruction of the T-10 vertebral body, which was concerning for tumor growth. The patient underwent angiographic embolization followed by single-stage posterior en bloc vertebrectomy with placement of a cage and posterior instrumentation and fusion without event. However, approximately 24 hours after surgery, the patient's systolic blood pressure was consistently no higher than 70 mm Hg. During this time, he began suffering from severe bilateral lower-extremity weakness. His systolic blood pressure increased with dopamine, and his strength immediately improved. The patient's oral regimen of adrenergic blockade was stopped, and he recovered without event. Since that time, the patient has been symptom free and requires no antihypertensive medication. The role of en bloc resection for metastatic lesions of the spine is controversial but may be warranted in cases of metastatic pheochromocytoma. En bloc resection avoids intralesional tumor resection and thus may help prevent complications of hypertensive crisis associated with hormonal secretion and extensive blood loss, which are not uncommon with pheochromocytoma resection surgeries. Additionally, the role of en bloc spondylectomy in this setting may allow for metabolic treatment as patients with actively secreting tumors may no longer require antiadrenergic medications.

scholarly journals SPINE METASTASIS OF INTRACRANIAL HEMANGIOPERICYTOMA: CASE REPORT OF TWO TREATMENTS

2019 ◽  
Vol 27 (2) ◽  
pp. 108-112 ◽  
Author(s):  
Fernando Flores de Araujo ◽  
Douglas Kenji Narazaki ◽  
William Gemio Jacobsen Teixeira ◽  
Raphael Martus Marcon ◽  
Alexandre Fogaça Cristante ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Case Series ◽  
En Bloc Resection ◽  
Metastatic Lesion ◽  
Bloc Resection ◽  
En Bloc ◽  
Level Of Evidence ◽  
First Case

ABSTRACT Objective: To report the use of two techniques (radiosurgery and en bloc vertebrectomy) on the same patient for the treatment of two metastases in different sites of the spine arising from intracranial hemangiopericytoma. Intracranial hemangiopericytomas are rare, comprising approximately 2.4% of meningeal tumors and <1% of all tumors of the central nervous system. Metastases to the spine are even rarer: The largest case series reported in the literature has 5 and 7 cases. Methods: A 37-year-old man diagnosed with intracranial hemangiopericytoma was referred for a metastatic lesion in T12 and underwent en bloc resection using the Tomita technique. Results: The disease evolved with a metastasis to T2 treated by radiosurgery with 1600 cGy. The patient died 1,706 days after the en bloc resection of T12 and 1324 days after the radiosurgery of T2, and no recurrence occurred in these locations due to progression of the systemic diseases (liver and central nervous system). Conclusion: This is the first case reported in the literature in which two different techniques were used to treat metastatic lesions in the spine from an intracranial hemangiopericytoma and is unique for its use of two treatments in the same patient. Level of evidence: V, case report

scholarly journals En bloc resection of a thoracic chordoma is possible using minimally invasive anterior access: An 8-year follow-up

2016 ◽  
Vol 7 (01) ◽  
pp. 138-140 ◽  
Author(s):  
Anand Goomany ◽  
Jake Timothy ◽  
Craig Robson ◽  
Abhay Rao
Keyword(s):  
Minimally Invasive ◽  
Thoracic Spine ◽  
Interbody Fusion ◽  
Traditional Approach ◽  
Tumor Resection ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
En Bloc ◽  
Perioperative Morbidity ◽  
First Case

ABSTRACTThoracic spine chordomas are a rare clinical entity and present several diagnostic and management challenges. Posterior debulking techniques are the traditional approach for the resection of thoracic tumors involving the vertebral body. Anterior approaches to the thoracic spine enable complete tumor resection and interbody fusion. However, this approach has previously required a thoracotomy incision, which is associated with significant perioperative morbidity, pain, and the potential for compromised ventilation and subsequent respiratory sequelae. The extreme lateral approach to the anterior spine has been used to treat degenerative disorders of the lower thoracic and lumbar spine, and reduces the potential complications compared with the anterior transperitoneal/transpleural approach. However, such an approach has not been utilized in the treatment of thoracic chordomas. We describe the first case of an en bloc resection of a thoracic chordoma via a minimally invasive eXtreme lateral interbody fusion approach.

5-Level Spondylectomy for En Bloc Resection of Thoracic Chordoma: Case Report

2011 ◽  
Vol 69 (suppl_2) ◽  
pp. onsE248-onsE256 ◽  
Author(s):  
Daniel M. Sciubba ◽  
Ziya L. Gokaslan ◽  
James H. Black ◽  
Oliver Simmons ◽  
Ian Suk ◽  
...  
Keyword(s):  
Case Report ◽  
Local Control ◽  
Percutaneous Biopsy ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Chest Wall Resection ◽  
En Bloc ◽  
Primary Tumors ◽  
First Case ◽  
Wire Saw

Abstract BACKGROUND AND IMPORTANCE Primary tumors of the spine are considered for en bloc resection to improve local control and even obtain cure. Anatomic restrictions often prohibit extensive resections with negative margins that are safe and feasible. We report the first case involving a patient with a large chordoma of the thoracic spine who underwent a successful 5-level spondylectomy with bilateral chest wall resection for en bloc resection without neurologic compromise. CLINICAL PRESENTATION A 26-year-old woman with a chest mass was found to have a T1-5 chordoma via a percutaneous biopsy. En bloc resection of the mass was thought to be the best option for long-term local control and possible cure. She presented without neurologic or pulmonary dysfunction. The patient underwent a 3-stage procedure. The first stage involved a posterior C2-T8 exposure, allowing release of posterior elements from C7 to T6 and instrumented stabilization from C2 to T8. T1-5 ribs were cut bilaterally, and 2 wire saws were placed ventral to the thecal sac at the C7-T1 and T5-6 disc levels. The second stage involved a right-sided thoracotomy, and the T5-6 wire saw was used to complete the lower osteotomy. The third stage involved completion of the C7-T1 osteotomy with the wire saw, delivery of the tumor specimen en bloc, ventral reconstruction of the spine with a titanium mesh cage, and bilateral thoracoplasty. CONCLUSION This is the first case report of a 5-level spondylectomy for en bloc resection of an extensive thoracic chordoma via a bilateral thoractomy without neurologic compromise.

Sign in / Sign up

Export Citation Format

Share Document