scholarly journals Technetium-99m Ciprofloxacin Imaging in the Diagnosis of Postsurgical Bony Infection and Evaluation of the Response to Antibiotic Therapy: A Case Report

2005 ◽  
Vol 13 (2) ◽  
pp. 190-194 ◽  
Author(s):  
B Singh ◽  
BR Mittal ◽  
A Bhattacharya ◽  
A Aggarwal ◽  
ON Nagi ◽  
...  

The use of radiolabelled antibiotics is fast emerging as a promising diagnostic test for the detection of infective lesions, because of their specific binding to the bacterial component. Ciprofloxacin is a broad-spectrum antibiotic that has been used as a radiolabelled antibiotic in both the diagnosis of infections in rabbits and in clinical trials on humans. The diagnosis of skeletal microbial infections remains a challenge, especially in orthopaedic patients with implants. We present a case report of a patient with undiagnosed and unrelenting pain in the lower third of the left leg, which had persisted for 6 months. A novel scintigraphy, which was developed in-house using a 99mTc ciprofloxacin single vial kit, was used for diagnosing the active bacterial infection. A 99mTc methylene diphosphonate bone scan was also performed to locate precisely the site of the lesion. Gradually increasing concentrations of both the radiotracers confirmed the presence of active bacterial infection in the distal third of the left tibia. Follow-up scanning after antibiotic therapy showed the disappearance of the pooling of 99mTc ciprofloxacin, indicating a good response. Therefore, 99mTc ciprofloxacin has good diagnostic and prognostic applications in deep-seated covert skeletal microbial infections. However, the persistence of a focal concentration detected by the 99mTc methylene diphosphonate scan was attributed to the inflammatory and not the infective pathology.

Author(s):  
Guilherme Finger ◽  
Maria Eduarda Conte Gripa ◽  
Tiago Paczko Bozko Cecchini ◽  
Tobias Ludwig do Nascimento

AbstractNocardia brain abscess is a rare clinical entity, accounting for 2% of all brain abscesses, associated with high morbidity and a mortality rate 3 times higher than brain abscesses caused by other bacteria. Proper investigation and treatment, characterized by a long-term antibiotic therapy, play an important role on the outcome of the patient. The authors describe a case of a patient without neurological comorbidities who developed clinical signs of right occipital lobe impairment and seizures, whose investigation demonstrated brain abscess caused by Nocardia spp. The patient was treated surgically followed by antibiotic therapy with a great outcome after 1 year of follow-up.


2018 ◽  
Vol 36 (77) ◽  
Author(s):  
Pablo Emilio Molano Valencia ◽  
Bibiana Inés Yepes Ramírez ◽  
Alix María Varela Peñaranda

RESUMEN. Antecedentes: La técnica en rollo modificado se ha utilizado ampliamente para mejorar el aspecto estético de las deficiencias de rebordes alveolares durante el tratamiento de rehabilitación y disminuir dolor posoperatorio. Objetivo: Describir un caso clínico en el que se realizó un aumento del reborde alveolar por medio de técnica en rollo modificada y se presentó un absceso durante las primeras semanas posoperatorias. Se describe también manejo clínico del caso. Resultados: Después del diagnóstico clínico y microbiológico, se realizó tratamiento antibiótico. En el control a los cuatro meses se observó resolución completa del absceso.ABSTRACT. Background: The modified roll technique has been widely used to improve the aesthetic appearance of alveolar ridge deficiencies during the oral rehabilitation treatments and to reduce postoperative pain. Purpose: To describe a case of alveolar ridge increase through modified roll technique and an abscess that occurred during the initial postoperative weeks. The clinical treatment of the case is also described. Results: After clinical and microbiological diagnosis, the patient underwent antibiotic therapy. Four-month follow-up showed complete resolution of the abscess. 


2018 ◽  
Vol 1 (11) ◽  
pp. 334-338
Author(s):  
Shweta Bansal ◽  
Ruchi Juneja ◽  
Gyanendra Mishra ◽  
Akshay Nambiar

Cutaneous draining sinus tracts of odontogenic origin often are a diagnostic challenge. A delay in correctly diagnosing these types of lesions can result in unnecessary antibiotic therapy and surgical treatment. This case report presents the clinical course of two cases with extra-oral sinus tract formation, from diagnosis and treatment to short-term follow-up and evaluation. These facial lesions were initially misdiagnosed as lesions of non-odontogenic origin. Later on an odontogenic cause was identified and endodontic intervention resulted in resolution of the problem, confirming the initial misdiagnosis.


Author(s):  
Poornima Jalawadi ◽  
Aiyanna PP

Pilonidal Sinus (PNS) is a commonest presentation in surgical practice with a high prevalence rate at more than 1 million cases per year in India, where as incidence is about 26 per 1,00,000 population. A 30-year-old male patient presented with PNS after an unsuccessful excision followed by antibiotic therapy. The challenge in this case was not only to excise the tract but also preventing its recurrence. Adopting the principles of Vranopakramas using Ksharakarma, Utsadana karma described in Ayurveda helped to manage the PNS effectively without any recurrence after 32 months of follow-up.


2020 ◽  
Vol 8 ◽  
Author(s):  
Lamiae Hallab ◽  
Bouchra Taleb

Erysipelas is a superficial cutaneous process that is usually restricted to the dermis, but with prominent lymphatic involvement commonly caused by streptococci. We present a patient who was admitted for swelling and erythema of his left cheek. We diagnosed facial erysipelas, the curative treatment was based on the prescription of effective antibiotic therapy against streptococci and bacteria producing β-lactamase (staphylococci). Removal of the remaining teeth was scheduled during medical treatment. At a 4-month follow-up after dental removal, there has been no recurrence of erysipelas.Through a clinical case of facial erysipelas, this work allows illustrating the specificities of this pathology.


2011 ◽  
Vol 15 (02) ◽  
pp. 241-244
Author(s):  
Raquel Crisostomo Lima Verde ◽  
Bruno Farias Lessa ◽  
Clara Mônica Figueiredo de Lima ◽  
Marcus Miranda Lessa ◽  
Helio Andrade Lessa ◽  
...  

Summary Introduction: Among the rhinosinusitis complications, the orbital are the most frequent ones, occurring mostly in the youngsters and children. Simultaneous complications involving the intracranial orbit and space are extremely rare, but they must be severely treated for they have a high rate of morbidity and mortality. Case report: In this work, the authors report a case of a patient who appeared to have preseptal cellulites and epidural abscess, in the form of simultaneous complications of an acute rhinosinusitis. In the patient of this case, choice was made for a clinic treatment associated with a nasosinusal endoscopic surgery and neurosurgical drainage of the intracranial abscess. CT was enough to achieve the diagnosis of this case. Final commentaries: However, it is recommended that, in cases where patients have rhinosinusitis complications, an extensive intracranial investigation needs to be deepened even when this is not so evident in the beginning. Given the polymicrobial nature of these infections, an aggressive culture-guided antibiotic therapy and a multidisciplinary follow-up significantly increase the likelihood of success.


2021 ◽  
Vol 11 (3) ◽  
pp. 170-173
Author(s):  
Chandrakanth HV ◽  
Hemanth Kumar RG ◽  
Smitha Rani

Necrotizing fasciitis is an uncommon lethal bacterial infection that involves the subcutaneous tissue and fascia. It can be mono or polymicrobial infection. The diagnosis is mainly dependent on clinical signs and symptoms. Trauma is the commonest cause for it. The early signs and symptoms may mimic cellulitis. We present a case of necrotizing fasciitis following an assault. The patient was received in a state of shock. Despite all measures, the patient could not be saved. Early debridement and antibiotic therapy have a key role in the prognosis of the disease. Medicolegal issues can arise when the disease develops post-assault because of the vague and unpredictable nature of the disease and its challenging prognosis.


2021 ◽  
Vol 12 (Supp 1) ◽  
pp. 21-25
Author(s):  
Khadim Diop ◽  
Boubacar Ahy Diatt ◽  
Saer Diadie

Mycetoma is a rare and neglected tropical disease among children. Extrapodal forms, in particular the buttock, are serious because they expose to visceral extension. We are reporting an observation remarkable for its clinical tumor presentation in a child. An 11-year-old boy was admitted at to the dermatology department for a buttock tumor that has been evolving for 2 years. Physical examination showed a multinodular, polyfistulized, and inflammatory tumor emitting red granules located in the buttocks. Mycological examination isolated Actinomadure pelletieri that confirms the diagnosis of actinomicotic mycetoma. The evolution, after a two-year follow-up, was positive under antibiotic therapy combining cotrimoxazol, clavulanic acid amoxicillin and streptomycin. Our observation is specific by the occurrence of a pseudotumoral actinomycotic buttock mycetoma in a child, the diagnostic delay and the favorable evolution without recurrence after a follow-up of 24-month.


2011 ◽  
Vol 21 (1) ◽  
pp. 11-21 ◽  
Author(s):  
Farzan Irani ◽  
Rodney Gabel

This case report describes the positive outcome of a therapeutic intervention that integrated an intensive, residential component with follow-up telepractice for a 21 year old male who stutters. This therapy utilized an eclectic approach to intensive therapy in conjunction with a 12-month follow-up via video telepractice. The results indicated that the client benefited from the program as demonstrated by a reduction in percent stuttered syllables, a reduction in stuttering severity, and a change in attitudes and feelings related to stuttering and speaking.


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