scholarly journals An Equipment-Free, Paper-Based Electrochemical Sensor for Visual Monitoring of Glucose Levels in Urine

2019 ◽  
Vol 24 (5) ◽  
pp. 499-505
Author(s):  
Maedeh Mohammadifar ◽  
Mehdi Tahernia ◽  
Seokheun Choi
Keyword(s):  
Glucose Sensor ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Glucose Sensing ◽  
Glucose Biosensor ◽  
Paper Strip ◽  
Visual Responses ◽  
Free Paper ◽  
Light Emitting ◽  
Glucose Levels

A novel electrochemical glucose sensor was created for a simple but semiquantitative visual screening of specific glucose concentrations in urine. This noninvasive glucose biosensor integrated a disposable, paper-based sensing strip and a simple amplifier circuit with a visual readout. The paper strip consisted of five enzyme-activated electrodes. Each electrode was connected to a specific indicator circuit that triggered a light-emitting diode (LED) when a predefined glucose concentration was reached. The device features (1) low-cost, disposable, paper-based glucose oxidase (GOx)/poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) sensing electrodes, (2) simple signal amplification, and (3) on-site, rapid, and visual detection. The sensor generated reliable, discrete visual responses to determine five glucose levels (1, 2, 3, 4, and higher than 4 mM) in urine in less than 2 min. This innovative approach will provide a simple but powerful glucose sensing paradigm for use in POC diagnostics.

Porphyrin doping of dichloride-bis(5,7-dichloroquinolin-8-olato)tin(IV) complex for electroluminescence

2013 ◽  
Vol 17 (05) ◽  
pp. 351-358 ◽  
Author(s):  
Mohammad Janghouri ◽  
Ezeddin Mohajerani ◽  
Mostafa M. Amini ◽  
Naser Safari
Keyword(s):  
Molecular Orbital ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Energy Levels ◽  
Orbital Energy ◽  
Homogeneous Layer ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Fundamental Structure ◽  
Organic Light

A method for obtaining red emission from an organic-light emitting diode has been developed by dissolving red and yellow dyes in a common solvent and thermally evaporating the mixture in a single furnace. Dichlorido-bis(5,7-dichloroquinolin-8-olato)tin(IV) complex ( Q2SnCl2 , Q = 5,7-dichloro-8-hydroxyquinoline) has been synthesized for using as a fluorescent material in organic light-emitting diodes (OLEDs). The electronic states HOMO (Highest Occupied Molecular Orbital)/LUMO (Lowest Occupied Molecular Orbital) energy levels explored by means of cyclic voltammetry measurements. A device with fundamental structure of ITO/PEDOT:PSS (55nm)/PVK (90nm)/ Q2SnCl2/Al (180nm) was fabricated and its electroluminescence performance at various thicknesses of light emitting layer (LEL) of Q2SnCl2 is reported. By following this step, an optimal thickness for the doping effect was also identified and explained. Finally a device with fundamental structure of ITO/PEDOT:PSS (55nm)/PVK (90nm)/meso-tetraphenylporphyrin (TPP): Q2SnCl2 (75nm)/ Al (180nm) was fabricated and its electroluminescence performance at various concentrations of dye has been investigated. It is shown that this new method is promising candidate for fabrication of low cost OLEDs at more homogeneous layer.

scholarly journals Two glucose sensing/signaling pathways stimulate glucose-induced inactivation of maltose permease in Saccharomyces.

1997 ◽  
Vol 8 (7) ◽  
pp. 1293-1304 ◽  
Author(s):  
H Jiang ◽  
I Medintz ◽  
C A Michels
Keyword(s):  
Signaling Pathways ◽  
Glucose Transport ◽  
Glucose Sensor ◽  
Constitutive Expression ◽  
Glucose Sensing ◽  
Regulation Of Transcription ◽  
Carbohydrate Utilization ◽  
Maltose Permease ◽  
Glucose Levels ◽  
Dependent Signal

Glucose is a global metabolic regulator in Saccharomyces. It controls the expression of many genes involved in carbohydrate utilization at the level of transcription, and it induces the inactivation of several enzymes by a posttranslational mechanism. SNF3, RGT2, GRR1 and RGT1 are known to be involved in glucose regulation of transcription. We tested the roles of these genes in glucose-induced inactivation of maltose permease. Our results suggest that at least two signaling pathways are used to monitor glucose levels. One pathway requires glucose sensor transcript and the second pathway is independent of glucose transport. Rgt2p, which along with Snf3p monitors extracellular glucose levels, appears to be the glucose sensor for the glucose-transport-independent pathway. Transmission of the Rgt2p-dependent signal requires Grr1p. RGT2 and GRR1 also play a role in regulating the expression of the HXT genes, which appear to be the upstream components of the glucose-transport-dependent pathway regulating maltose permease inactivation. RGT2-1, which was identified as a dominant mutation causing constitutive expression of several HXT genes, causes constitutive proteolysis of maltose permease, that is, in the absence of glucose. A model of these glucose sensing/signaling pathways is presented.

Low Cost Cooling Device for High Power LED Lamps

2020 ◽  
Author(s):  
Pamela Martinez-Vega ◽  
Araceli Lopez-Badillo ◽  
J. Luis Luviano-Ortiz ◽  
Abel Hernandez-Guerrero ◽  
Jaime G. Cervantes
Keyword(s):  
Reference Model ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Cost Effective ◽  
Heat Sinks ◽  
Modern World ◽  
Type Model ◽  
Light Emitting

Abstract The modern world progressively demands more energy; according to forecasts energy consumption will grow at an average annual rate of 3 percent. Therefore, it is necessary to purchase products or devices that are efficient and environmentally friendly. Technology in LED (Light Emitting Diode) lighting is presented as an alternative to energy saving, since LEDs have proven to be extremely efficient, have a long service life and their cost-effective ratio is very good. However, the heat emitted by the LED chip must be dissipated effectively, since the overheating of the chip reduces the efficiency and lifetime of the lamp. Therefore, heat sinks that are reliable, efficient and inexpensive should be designed and built. The present work proposes new designs for heat sinks in LED lamps, some of the models in the design of the fins refer to the Fibonacci series. The models proposed in the present work that have a significant advantage are the Type 1E Model (5.2% mass savings and better thermal efficiency of 8.33%), GR Type 1 Model (3.12% lighter and 3.33% more efficient) and the GRL Type Model (4. 51% mass savings and 5.55% thermally more efficient) compared to the Type 2 Reference Model proposed by Jang et al. [12].

scholarly journals Preparation of Organic Light-Emitting Diode Using Coal Tar Pitch, a Low-Cost Material, for Printable Devices

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e62903 ◽  
Author(s):  
Miki Yamaoka ◽  
Shun-suke Asami ◽  
Nayuta Funaki ◽  
Sho Kimura ◽  
Liao Yingjie ◽  
...  
Keyword(s):  
Light Emitting Diode ◽  
Low Cost ◽  
Coal Tar ◽  
Coal Tar Pitch ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Organic Light

1.331μm Narrow-Bandwidth Light Source Based on Polymer Micro-Blazed Grating

2008 ◽  
Author(s):  
Hairong Wang ◽  
Xianni Gao ◽  
Guoliang Sun ◽  
Yulong Zhao ◽  
Zhuangde Jiang
Keyword(s):  
Light Source ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Diffraction Order ◽  
Blazed Grating ◽  
Light Emitting ◽  
Led Light ◽  
Narrow Bandwidth ◽  
Narrow Width ◽  
The Cost

In order to detect methane (CH4) accurately and reliably, this paper presents a sensor which consists of infrared diode, fixtures, blazed grating, to realize the extremely narrow-bandwidth light at wavelength of 1.331μm. Based on factors such as compatibility with the transmission characteristics of silica fiber and the cost, a LED (light-emitting diode) with center wavelength of 1.3μm is selected. The LED light is modulated as the parallel light beam. As the light is incident in a micro-blazed grating with certain angle, by diffraction and interference, the light will output the maximum light intensity of its diffraction order at 1.331 μm, which just is an absorption peak of CH4. Micro-blazed grating applied here is low cost and easy replication by various ways, which makes extreme narrow width wavelength possible. Simulation and analysis indicate the designed prototype can output 1.331μm with bandwidth from 1.32907μm to 1.332495μm. With the light source basing on light dividing system, more reliable and higher sensitive measurement of the dangerous gases such as methane and carbon monoxide (CO) can be realized.

scholarly journals Light-Emitting-Diode-Based Multispectral Photoacoustic Computed Tomography System

Sensors ◽  
2019 ◽  
Vol 19 (22) ◽  
pp. 4861 ◽  
Author(s):  
Sumit Agrawal ◽  
Christopher Fadden ◽  
Ajay Dangi ◽  
Xinyi Yang ◽  
Hussain Albahrani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Molecular Imaging ◽  
Photoacoustic Imaging ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Tunable Laser ◽  
Cost Effective ◽  
Light Emitting ◽  
Multi Wavelength ◽  
Human Finger

Photoacoustic computed tomography (PACT) has been widely explored for non-ionizing functional and molecular imaging of humans and small animals. In order for light to penetrate deep inside tissue, a bulky and high-cost tunable laser is typically used. Light-emitting diodes (LEDs) have recently emerged as cost-effective and portable alternative illumination sources for photoacoustic imaging. In this study, we have developed a portable, low-cost, five-dimensional (x, y, z, t, λ ) PACT system using multi-wavelength LED excitation to enable similar functional and molecular imaging capabilities as standard tunable lasers. Four LED arrays and a linear ultrasound transducer detector array are housed in a hollow cylindrical geometry that rotates 360 degrees to allow multiple projections through the subject of interest placed inside the cylinder. The structural, functional, and molecular imaging capabilities of the LED–PACT system are validated using various tissue-mimicking phantom studies. The axial, lateral, and elevational resolutions of the system at 2.3 cm depth are estimated as 0.12 mm, 0.3 mm, and 2.1 mm, respectively. Spectrally unmixed photoacoustic contrasts from tubes filled with oxy- and deoxy-hemoglobin, indocyanine green, methylene blue, and melanin molecules demonstrate the multispectral molecular imaging capabilities of the system. Human-finger-mimicking phantoms made of a bone and blood tubes show structural and functional oxygen saturation imaging capabilities. Together, these results demonstrate the potential of the proposed LED-based, low-cost, portable PACT system for pre-clinical and clinical applications.

Dual Fiber-Optic Fabry–Perot Interferometer Temperature Sensor with Low-Cost Light-Emitting Diode Light Source

2008 ◽  
Vol 47 (4) ◽  
pp. 3236-3239 ◽  
Author(s):  
Mu-Chun Wang ◽  
Zhen-Ying Hsieh ◽  
Yuan-Tai Tseng ◽  
Fan-Gang Tseng ◽  
Heng-Sheng Huang ◽  
...  
Keyword(s):  
Light Source ◽  
Temperature Sensor ◽  
Fiber Optic ◽  
Light Emitting Diode ◽  
Low Cost ◽  
Light Emitting ◽  
Fabry Perot
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