scholarly journals Immunohistochemistry as a valuable tool to assess CD30 expression in peripheral T-cell lymphomas: high correlation with mRNA levels

Blood ◽  
2014 ◽  
Vol 124 (19) ◽  
pp. 2983-2986 ◽  
Author(s):  
Céline Bossard ◽  
Maria Pamela Dobay ◽  
Marie Parrens ◽  
Laurence Lamant ◽  
Edoardo Missiaglia ◽  
...  
Keyword(s):  
T Cell ◽  
Protein Expression ◽  
Mrna Levels ◽  
Clinical Tool ◽  
T Cell Lymphomas ◽  
Key Points ◽  
Mrna And Protein Expression ◽  
Highly Correlated ◽  
Peripheral T Cell Lymphomas

Key Points IHC is a valuable clinical tool for assessing CD30+ PTCL patients who may respond to CD30-targeting treatment. CD30 mRNA and protein expression are highly correlated.

scholarly journals Five-year outcomes for frontline brentuximab vedotin with CHP for CD30-expressing peripheral T-cell lymphomas

Blood ◽  
2018 ◽  
Vol 131 (19) ◽  
pp. 2120-2124 ◽  
Author(s):  
Michelle A. Fanale ◽  
Steven M. Horwitz ◽  
Andres Forero-Torres ◽  
Nancy L. Bartlett ◽  
Ranjana H. Advani ◽  
...  
Keyword(s):  
T Cell ◽  
Response Rate ◽  
Brentuximab Vedotin ◽  
T Cell Lymphomas ◽  
Key Points ◽  
Peripheral T Cell Lymphomas

Key Points 100% response rate (92% CR) in 26 patients treated with frontline BV+CHP. After ∼5 years, 50% remained in CR (PFS 37.8+ to 66.0+ months). 18 of 19 patients (95%) with treatment-emergent PN reported resolution or improvement in symptoms; 9 had resolution of all PN events.

scholarly journals Central nervous system relapse in peripheral T-cell lymphomas: a Swedish Lymphoma Registry study

Blood ◽  
2015 ◽  
Vol 126 (1) ◽  
pp. 36-41 ◽  
Author(s):  
Fredrik Ellin ◽  
Jenny Landström ◽  
Mats Jerkeman ◽  
Thomas Relander
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
T Cell ◽  
B Cell ◽  
Central Nervous System Relapse ◽  
Registry Study ◽  
Cns Involvement ◽  
T Cell Lymphomas ◽  
Key Points ◽  
Peripheral T Cell Lymphomas

Key Points CNS involvement at relapse/progression in PTCL occurred at a frequency similar to what is seen in aggressive B-cell lymphomas. Outcome after relapse is generally very poor in patients with PTCL and is not significantly altered by presence of CNS involvement at relapse.

Real-world data on prognostic factors and treatment in peripheral T-cell lymphomas: a study from the Swedish Lymphoma Registry

Blood ◽  
2014 ◽  
Vol 124 (10) ◽  
pp. 1570-1577 ◽  
Author(s):  
Fredrik Ellin ◽  
Jenny Landström ◽  
Mats Jerkeman ◽  
Thomas Relander
Keyword(s):  
Stem Cell ◽  
Prognostic Factors ◽  
T Cell ◽  
Stem Cell Transplantation ◽  
Real World ◽  
Population Based ◽  
Real World Data ◽  
T Cell Lymphomas ◽  
Key Points ◽  
Peripheral T Cell Lymphomas

Key Points Population-based data show a favorable outcome with upfront autologous stem cell transplantation in PTCL. The addition of etoposide to CHOP was associated with favorable PFS in patients ≤60 years with PTCL.

Cytotoxic protein expression in natural killer cell lymphomas and in αβ and γδ peripheral T-cell lymphomas

1997 ◽  
Vol 183 (4) ◽  
pp. 432-439 ◽  
Author(s):  
Marie-Laure Boulland ◽  
Panagiotis Kanavaros ◽  
Janine Wechsler ◽  
Odile Casiraghi ◽  
Philippe Gaulard
Keyword(s):  
T Cell ◽  
Natural Killer Cell ◽  
Protein Expression ◽  
Natural Killer ◽  
Killer Cell ◽  
Cytotoxic Protein ◽  
T Cell Lymphomas ◽  
Peripheral T Cell Lymphomas
Sign in / Sign up

Export Citation Format

Share Document