scholarly journals THROMBOCYTOPENIC PURPURA COMPLICATING GOLD THERAPY FOR RHEUMATOID ARTHRITIS

Blood ◽  
1948 ◽  
Vol 3 (10) ◽  
pp. 1105-1111 ◽  
Author(s):  
STACY R. METTIER ◽  
ALICE Mc BRIDE ◽  
JONAH LI
Keyword(s):  
Rheumatoid Arthritis ◽  
Blood Platelets ◽  
Spontaneous Remission ◽  
Gold Salt ◽  
Gold Therapy ◽  
Thrombocytopenic Purpura ◽  
Fourth Patient ◽  
Dramatic Rise ◽  
Hemorrhagic Tendency

Abstract Of 160 patients treated with gold salt therapy, four developed thrombocytopenia with mild purpuric manifestations. In three patients there was a spontaneous remission and the hemorrhagic tendency disappeared in about one week’s time. In the fourth patient there was a second occurrence of thrombocytopenia which persisted over a period of four months, and finally failed to respond to transfusions. Splenectomy was followed by a dramatic rise in the blood platelets and recovery of the patient.

Effect of gold therapy on CD5+ B-cells and TCR ?? + T-cells in patients with rheumatoid arthritis

1991 ◽  
Vol 11 (4-5) ◽  
pp. 175-178 ◽  
Author(s):  
J. Hassan ◽  
C. Feighery ◽  
B. Bresnihan ◽  
A. Whelan
Keyword(s):  
Rheumatoid Arthritis ◽  
T Cells ◽  
B Cells ◽  
Gold Therapy

Gold therapy in rheumatoid arthritis

The Lancet ◽  
1991 ◽  
Vol 338 (8767) ◽  
pp. 642
Author(s):  
A. Samanta ◽  
S. Roy ◽  
K.L. Woods
Keyword(s):  
Rheumatoid Arthritis ◽  
Gold Therapy

scholarly journals Adverse events with ayurvedic medicines- possible adulteration and some inherent toxicities

2019 ◽  
Vol 4 ◽  
pp. 23 ◽  
Author(s):  
Buddhi Paudyal ◽  
Astha Thapa ◽  
Keshav Raj Sigdel ◽  
Sudeep Adhikari ◽  
Buddha Basnyat
Keyword(s):  
Rheumatoid Arthritis ◽  
Nephrotic Syndrome ◽  
Side Effects ◽  
Liver Injury ◽  
Adverse Events ◽  
Indian Subcontinent ◽  
Ayurvedic Medicine ◽  
Gold Salt ◽  
Traditional System ◽  
Wide Range

Ayurvedic medicine, a traditional system of medicine practiced in the Indian subcontinent is considered to be devoid of adverse events. We report three cases which highlight the possibility of adverse events related with the use of ayurvedic products. A 35 year old woman with hepatitis took ayurvedic powder medicine and swarnabhasma (gold salt) and had her liver injury worsened, possibly due to alkaloids, and developed nephrotic syndrome, possibly due to gold salt. A 57 year old hypertensive man was taking ayurvedic medicine containing reserpine which had long been withdrawn from the allopathic system of medicine due to wide range of side effects. A 47 year old woman with rheumatoid arthritis was taking an unknown tablet containing steroid as an adulterant for 2 years and developed side effects typical of steroid excess. We would like to highlight the fact that ayurvedic medicines do have propensity to cause adverse events due to adulteration or inherent constituents like alkaloids, and hence may not always be completely safe.

scholarly journals A Case of Rheumatoid Arthritis Accompanied by Thrombotic Thrombocytopenic Purpura

2015 ◽  
Vol 89 (1) ◽  
pp. 122
Author(s):  
Sung Min Kang ◽  
Ji Hyun Lee ◽  
In Hye Ku ◽  
Hae Koo Kim ◽  
Kyoung Sik Nam ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura

scholarly journals Early treatment of rituximab combined with eltrombopag for secondary thrombocytopenic purpura in rheumatoid arthritis

Medicine ◽  
2022 ◽  
Vol 101 (2) ◽  
pp. e28417
Author(s):  
Naidan Zhang ◽  
Chaixia Ji ◽  
Xiao Bao ◽  
Chengliang Yuan
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Treatment ◽  
Thrombocytopenic Purpura

scholarly journals Prevalence of Cytomegalovirus (CMV) and Epstein-Barr Virus (EBV) Subclinical Infection in Patients with Acute Immune Thrombocytopenic Purpura (ITP)

2021 ◽  
Author(s):  
Farshad Abbasi ◽  
Gholam Abbas Kaydani ◽  
Zari Tahannezhad ◽  
Mohsen Nakhaie ◽  
Ali Amin Asnafi ◽  
...  
Keyword(s):  
Immune Thrombocytopenic Purpura ◽  
Epstein Barr Virus ◽  
Blood Platelets ◽  
Control Group ◽  
Thrombocytopenic Purpura ◽  
Barr Virus ◽  
Causative Agents ◽  
Exact Etiology ◽  
Epstein Barr ◽  
Acute Itp

Background: Immune thrombocytopenic purpura (ITP) defined as a bleeding disorder in which the number and production of platelets reduced by the immune system; however, the destruction of peripheral blood platelets also occurs. Although its exact etiology and pathogenesis not already know, several studies have shown that Epstein-Barr virus (EBV) and cytomegalovirus (CMV) known as possible causative agents of ITP. This investigation aims to evaluate the presence of CMV and EBV in two groups of case and control by polymerase chain reaction (PCR). Materials and Methods: We considered the presence of CMV and EBV in 48 acute ITP patients and 48 healthy people. Study participants were recruited from Ahvaz Shafa Hospital between 2017 and 2018 and the presence of two viruses was investigated by (PCR). Results: Out of 48 acute ITP patients, the CMV DNA was detected from the blood of 12 (25%) patients and the EBV DNA from the blood of 2 (4.2%) other patients. In addition, only one patient was (2.1%) co-infected with CMV and EBV. In contrast, in 48 healthy subjects, 3 (6.6%) had CMV and none of the control group was infected with EBV. Conclusion: Due to the presence of both EBV and CMV in the acute ITP patients in Ahvaz, they can be considered as factors in the progression of this disease. Therefore, consideration of the methods of elimination and treatment of these two viruses in these patients may be used as a treatment strategy in ITP patients in the future.  

scholarly journals Remarkably similar response to gold therapy in HLA identical sibs with rheumatoid arthritis.

1986 ◽  
Vol 45 (12) ◽  
pp. 1004-1006 ◽  
Author(s):  
L B van de Putte ◽  
F Speerstra ◽  
P L van Riel ◽  
A M Boerbooms ◽  
P J van't Pad Bosch ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Similar Response ◽  
Gold Therapy
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