Feasibility of a cardiopulmonary exercise test (CPET) derived high-intensity interval training programme (HIIT) in idiopathic pulmonary fibrosis (IPF)

Author(s):  
Tim Wallis ◽  
Katarina Pontoppidan ◽  
Kerry Gove ◽  
David Hill ◽  
James Cullinane ◽  
...  
2020 ◽  
Vol 19 (1) ◽  
pp. 40
Author(s):  
Francisco Tiago Oliveira De Oliveira ◽  
Paula Guerra Duplat ◽  
Cristiane Maria Carvalho Costa Dias

Background: Cardiovascular rehabilitation has the objective of reducing the risks of mortality and within this intervention there are two training modalities: high intensity interval training (HIIT) and moderate continuous intensity training (MIT). The exercise prescription is performed by cardiopulmonary exercise test. There are differences about which one is the best training for this patient. Aim: To compare the effects of HIIT and moderate continuous training on the variables of the cardiopulmonary exercise test (CPX) in patients with coronary artery disease. Methods: This is a systematic review of randomized clinical trials on coronary artery disease. This study was registered on PROSPERO. The search was executed on the databases: Medline, Scielo, Lilacs and Pedro. The selection of studies was a two-phase process: Reading of title and abstract and reading of full article. The data extraction was performed by the transcription of information. The methodological quality was evaluated by the PEDro scale and the risk of bias scale. The statistical analysis was performed using the RStudio software by random effect model and was applied the Q-Cochran test to evaluate the statistical heterogeneity. Results: 10 clinical trials were included. The methodological quality assessed by PEDro generated scores of four to nine, and the bias risk scale detected a low risk of bias. For the variables:  VO2 peak (p = 0.04), Ventilatory Threshold (p = 0.05), HR max (p = 0.01), SBP max (p = 0.02), the HIIT proved to be more effective. The other variables did not present differences between the two modalities. Conclusion: HIIT showed to be the most effective training modality for the increase of VO2 max, Ventilatory Threshold, SBP max and HR max.Keywords: coronary heart disease, high intensity interval training, moderate continuous training.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Farouk Chrif ◽  
Tobias Nef ◽  
Kenneth J Hunt

Abstract Background Leg-press devices are one of the most widely used training tools for musculoskeletal strengthening of the lower-limbs, and have demonstrated important cardiopulmonary benefits for healthy and patient populations. Further engineering development was done on a dynamic leg-press for work-rate estimation by integrating force and motion sensors, power calculation and a visual feedback system for volitional work-rate control. This study aimed to assess the feasibility of the enhanced dynamic leg press for cardiopulmonary exercise training in constant-load training and high-intensity interval training. Five healthy participants aged 31.0±3.9 years (mean ± standard deviation) performed two cardiopulmonary training sessions: constant-load training and high-intensity interval training. Participants carried out the training sessions at a work rate that corresponds to their first ventilatory threshold for constant-load training, and their second ventilatory threshold for high-intensity interval training. Results All participants tolerated both training protocols, and could complete the training sessions with no complications. Substantial cardiopulmonary responses were observed. The difference between mean oxygen uptake and target oxygen uptake was 0.07±0.34 L/min (103 ±17%) during constant-load training, and 0.35±0.66 L/min (113 ±27%) during high-intensity interval training. The difference between mean heart rate and target heart rate was −7±19 bpm (94 ±15%) during constant-load training, and 4.2±16 bpm (103 ±12%) during high-intensity interval training. Conclusions The enhanced dynamic leg press was found to be feasible for cardiopulmonary exercise training, and for exercise prescription for different training programmes based on the ventilatory thresholds.


2020 ◽  
Vol 30 (10) ◽  
pp. 1409-1416
Author(s):  
Michael Khoury ◽  
Devin B. Phillips ◽  
Peter W. Wood ◽  
William R. Mott ◽  
Michael K. Stickland ◽  
...  

AbstractIntroduction:We evaluated the safety and feasibility of high-intensity interval training via a novel telemedicine ergometer (MedBIKE™) in children with Fontan physiology.Methods:The MedBIKE™ is a custom telemedicine ergometer, incorporating a video game platform and live feed of patient video/audio, electrocardiography, pulse oximetry, and power output, for remote medical supervision and modulation of work. There were three study phases: (I) exercise workload comparison between the MedBIKE™ and a standard cardiopulmonary exercise ergometer in 10 healthy adults. (II) In-hospital safety, feasibility, and user experience (via questionnaire) assessment of a MedBIKE™ high-intensity interval training protocol in children with Fontan physiology. (III) Eight-week home-based high-intensity interval trial programme in two participants with Fontan physiology.Results:There was good agreement in oxygen consumption during graded exercise at matched work rates between the cardiopulmonary exercise ergometer and MedBIKE™ (1.1 ± 0.5 L/minute versus 1.1 ± 0.5 L/minute, p = 0.44). Ten youth with Fontan physiology (11.5 ± 1.8 years old) completed a MedBIKE™ high-intensity interval training session with no adverse events. The participants found the MedBIKE™ to be enjoyable and easy to navigate. In two participants, the 8-week home-based protocol was tolerated well with completion of 23/24 (96%) and 24/24 (100%) of sessions, respectively, and no adverse events across the 47 sessions in total.Conclusion:The MedBIKE™ resulted in similar physiological responses as compared to a cardiopulmonary exercise test ergometer and the high-intensity interval training protocol was safe, feasible, and enjoyable in youth with Fontan physiology. A randomised-controlled trial of a home-based high-intensity interval training exercise intervention using the MedBIKE™ will next be undertaken.


Sports ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 92
Author(s):  
Timo Kirchenberger ◽  
Sascha Ketelhut ◽  
Reinhard G. Ketelhut

The effects of moderate-intensity continuous training (MICT) and a combination of MICT and high-intensity interval training (HIIT) on rowing performance and VO2peak were investigated in young athletes. Seventeen well-trained rowers (aged 15 ± 1.3 years) were randomly allocated to an intervention (IG) (n = 10) and control group (CG) (n = 7). During 8 weeks, both groups took part in the regular rowing training (3×/week MICT, 70–90 min, 65–70% of HRpeak + 2×/week resistance training). The IG completed an additional high-intensity interval training twice weekly (2 × 4 × 2 min at ≈95% of HRpeak, 60 s rest). Instead of the HIIT, the CG completed two more MICT sessions (70–90 min, 65–70% of HRpeak). Before and after the intervention, a 2000 m time trial and an exercise test were performed. The IG showed a significant improvement (p = 0.001) regarding the absolute rowing time in the graded exercise test. Furthermore, the intervention group showed a significant increase in relative VO2peak (p = 0.023), a significant increase in absolute VO2peak (p = 0.036), and a significant improvement in the 2000 m time trail (p = 0.003). No significant changes could be detected in the CG. The interaction effects were not significant. A mixed-intensity training, including HIIT, was beneficial on rowing performance and VO2peak in highly trained athletes.


2020 ◽  
Vol 41 (06) ◽  
pp. 365-372
Author(s):  
Omar Andrade-Mayorga ◽  
Rodrigo Mancilla ◽  
Erik Díaz ◽  
Cristian Alvarez

AbstractTo describe and compare the acute heart rate changes during an incremental exercise test and high-intensity interval training (HIIT) in subjects of different glucose control. Seventy-five adults were allocated into three groups: Normoglycaemic (NG, n=32), Pre- (PreT2D, n=30) and Type 2 diabetic (T2D, n=13) subjects. Subjects performed an incremental cycling test to determine cardiorespiratory fitness (VO2max), maximum heart rate (HRmax) and HR recovery post maximal effort, as well as a HIIT cycling session. HR variations are reported as HR pre (HR-preINT), and post interval (HR-postINT), percentage of maximum HR (%HRmax), delta of HR increased (∆HRINT), and delta HR recovery after each interval (∆HRR). By groups, there was a significant difference for the %HRmax in 1st and 2nd, but not in intervals 3rd to 10th between Pre-T2D and T2D groups. There were significant differences for the %HRmax in 1st to 2nd intervals between Pre-T2D and T2D groups. Significant (P<0.05) differences at some intervals were found for ΔHRINT, and ΔHRR. These findings suggest that the HR during an incremental exercise test, and from a typical 10-intervals based HIIT protocol could be used as an intensity marker for individuals independent of their glycaemic control.


2021 ◽  
Author(s):  
Yuan-Yang Cheng ◽  
Shih-Yi Lin ◽  
Shin-Tsu Chang ◽  
Chu-Hsing Lin ◽  
Pin-Kuei Fu

Abstract Idiopathic pulmonary fibrosis (IPF) is a rare lung disease with high mortality. Finding an effective predictor of survival is therefore important for both clinicians and patients. In this prospective observational study, we evaluated the prognostic value of the parameters of cardiopulmonary exercise test (CPET), pulmonary function test (PFT), 6-min walk test (6MWT), and certain questionnaires on mortality in Asian patients with IPF. A total of 34 patients diagnosed with IPF were enrolled and followed up for 12 months, during which 6 patients died. The non-survivors had significantly higher minute ventilation to carbon dioxide output (VE/VCO2) slope, more oxygen desaturation during CPET and 6MWT, less heart rate recovery one minute after CPET, higher dead space, higher Gender-Age-Physiology (GAP) index and Modified Medical Research Council (mMRC) score. GAP index, mMRC score, VE/VCO2 slope, and end-tidal partial pressure of carbon dioxide (PETCO2) at maximal exercise demonstrated an area under curve (AUC) of >0.7, and the corresponding cutoff values were 4, 2, 35.1 and 3.6 kPa. Therefore, GAP index, mMRC scores, VE/VCO2 slope, and PETCO2 at maximal exercise could be important predictors for mortality in Asian patients with IPF.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 743-P
Author(s):  
ANGELA S. LEE ◽  
KIMBERLEY L. WAY ◽  
NATHAN A. JOHNSON ◽  
STEPHEN M. TWIGG

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 553-P
Author(s):  
GIDON J. BÖNHOF ◽  
ALEXANDER STROM ◽  
MARIA APOSTOLOPOULOU ◽  
DOMINIK PESTA ◽  
MICHAEL RODEN ◽  
...  

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