scholarly journals The impact of childhood acute rotavirus gastroenteritis on the parents’ quality of life: prospective observational study in European primary care medical practices

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Javier Diez Domingo ◽  
Marian Patrzalek ◽  
Luigi Cantarutti ◽  
Benoit Arnould ◽  
Juliette Meunier ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Care ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Medical Practices ◽  
Rotavirus Gastroenteritis ◽  
The Impact

scholarly journals P.045 Quality of life and treatment satisfaction in onabotulinumtoxinA-treated cervical dystonia patients: multicentre, prospective, observational study, posture

2016 ◽  
Vol 43 (S2) ◽  
pp. S32-S32
Author(s):  
M Petitclerc ◽  
M Bhogal ◽  
S Dhani ◽  
L Belle Blagrove
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Cervical Dystonia ◽  
Treatment Satisfaction ◽  
Prospective Observational Study ◽  
Rating Scale ◽  
Numeric Rating Scale ◽  
Post Treatment ◽  
The Impact

Background: Health-related quality of life (HRQoL) data is valuable, but limited. This analysis describes the impact of onabotulinumtoxinA treatment on HRQoL and level of treatment satisfaction in cervical dystonia (CD) patients. Methods: A multicenter, prospective, observational study in CD patients initiating onabotulinumtoxinA treatment (NCT01655862); ≤8 treatments administered at the physician’s discretion. Primary measures (baseline, 4/8 weeks post-treatment, and before final treatment): pain numeric rating scale (PNRS) and cervical dystonia impact profile questionnaire (CDIP-58). Secondary measures (8 weeks post-treatment): patient/physician treatment satisfaction. Results: 61 patients (31.3-86.3 years old) were enrolled (efficacy cohort); majority had moderately severe CD (77.0%) and were female (77%). CDIP-58 domain and PNRS scores decreased from baseline, with significant changes (p<.0001) by 4 weeks post-treatment 3 (mean±SD): symptoms (-18.8±16.1), daily activities (-7.2±13.7), psychosocial sequelae (-17.4±13.4), and PNRS (-1.8±3.3). Most patients (78.0% and 94.4%) felt their condition was improved and majority of physicians (68.9% and 75.0%) indicated satisfaction with patients’ responses following treatments 1 and 2, respectively. 27 patients reported 56 treatment-related adverse events (52 resolved, 4 ongoing); none were serious. Conclusions: No new safety signals were identified. Patients and physicians appear to be satisfied with onabotulinumtoxinA treatment for CD. Results suggest that onabotulinumtoxinA treatment may help improve HRQoL.

scholarly journals Implementing spirometry and fractional exhaled nitric oxide testing in childhood asthma management in UK primary care: an observational study to examine training and implementation cost and impact on patient’s health use and outcome

2021 ◽  
pp. archdischild-2020-319310
Author(s):  
Yaling Yang ◽  
David KH Lo ◽  
Caroline Beardsmore ◽  
Damian Roland ◽  
Matthew Richardson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nitric Oxide ◽  
Primary Care ◽  
Health Status ◽  
Observational Study ◽  
Healthcare Utilisation ◽  
Exhaled Nitric Oxide ◽  
Related Quality ◽  
The Impact

ObjectivesImplementation of guidelines into clinical practice is challenging and complex. This study aims to (1) identify the training needs and capacity requirements, and (2) explore the impact on healthcare utilisation and asthma-related quality of life of implementing both spirometry and fraction of exhaled nitric oxide in diagnosis of asthma among children in the UK primary care.MethodsTen UK general practitioner practices and a total of 612 children (5–16 years) with diagnosed or suspected asthma were invited to participate in this prospective observational study. The total times that the trainer and trainee clinical staff spent on developing the training package, providing and receiving, and performing and interpreting the two tests as part of routine child asthma review were collected, and costs were calculated. We compared healthcare utilisation and asthma-related and general health-related quality of life data between the 6 months before and after the asthma review guided by objective tests.ResultsThe average training cost for the 27 primary care clinical members was £1395. The average cost to implement and deliver the test-guided asthma review among the 612 included children was £22. In the 6 months following the tests-guided asthma review, both unplanned primary care attendance, and hospital admissions were reduced, and the asthma-related health status increased significantly.ConclusionThis study provides robust cost estimates of the resources needed to implement the National Institute for Health and Care Excellence asthma guideline. It also demonstrates the potential to save healthcare costs and improve health status among asthmatic children by implementing this guideline.

scholarly journals Evaluation of drug utilization pattern, quality of life and pharmaco-economics in patients of contact dermatitis: a prospective observational study

2021 ◽  
Vol 8 (1) ◽  
pp. 39
Author(s):  
Jolly M. Harkhani ◽  
Ashish Jagati ◽  
Hemant Tiwari ◽  
Shikha V. Sood ◽  
Supriya D. Malhotra
Keyword(s):  
Quality Of Life ◽  
Contact Dermatitis ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Health Care Facilities ◽  
Average Score ◽  
Total Cost ◽  
The Impact

<p class="abstract"><strong>Background: </strong>Contact dermatitis (CD) is a common inflammatory skin condition due to T-cell mediated immune reaction on exposure to different allergens. The disease significantly affects Quality of Life (QoL) and all over impact can be seen in Pharmacoeconomics.</p><p class="abstract"><strong>Methods: </strong>This is the prospective observational study done between October 2019 to February 2020 at Dermatology outpatient department (OPD) of a tertiary care teaching hospital. Patients diagnosed with CD aged eighteen years or older of either gender and willing to give written consent were included in study. The impact of CD on the QoL of affected persons was assessed using the Dermatology Life Quality Index (DLQI). Direct, indirect and total cost as well as percentage variation in cost of individual drugs was calculated for Pharmacoeconomics analysis.</p><p class="abstract"><strong>Results:</strong> The study population consisted of 180 patients. The most commonly prescribed drugs were corticosteroids (47.44%). The average score of DLQI at baseline was 8.97±4.85. The DLQI score was significantly more impaired in women as compared to men (12.91versus 4.93) (p=0.0001). Average income per month was 11,611.11±230.34₹. The average direct, indirect and total cost was 131.55±70.55 ₹, 136.44±16.93 ₹ and 168.11±74.08₹ respectively. The percentage variation of cost was largest for prednisolone 5 mg tablet and least for clobetasol cream (0.05%).</p><p class="abstract"><strong>Conclusions: </strong>The impact of CD on QoL and Pharmacoeconomic burden is significant and requires specific attention in health care facilities.  </p>

scholarly journals Quality of Life in Patients with Nasal Obstruction after Septoplasty: A Single Institution Prospective Observational Study

2021 ◽  
Author(s):  
Justyna Dąbrowska-Bień ◽  
Henryk Skarżyński ◽  
Sebastian Filip Górski ◽  
Piotr Henryk Skarżyński
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Nasal Obstruction ◽  
Prospective Observational Study ◽  
Common Symptom ◽  
Single Institution ◽  
High Satisfaction ◽  
Symptom Evaluation ◽  
The Individual

Abstract Introduction Nasal obstruction is a common symptom in otorhinolaryngological practice. It can impact significantly on the quality of life of the individual. Objective The primary goal of the present study was to evaluate quality of life after septoplasty in adults with nasal obstruction. A secondary goal was to assess the effectiveness of septoplasty. Methods This was a single institution prospective observational study. Patients had experienced septal deviation and symptomatic nasal obstruction with no benefit from medical treatment. There were 51 patients who completed the Nasal Obstruction Symptom Evaluation (NOSE-POL) scale as well as theVisual Analogue Scale (VAS) before undergoing septoplasty, 3 months later, and finally 7 months after surgery. Patients evaluated changes in their nasal obstruction and changes in their quality of life using the Clinical Global Impression Scale (CGI-S). Results There was a significant improvement in nasal obstruction after septoplasty. Before septoplasty, the mean score on NOSE was 60.3 ± 20.4; 3 months after surgery, it was 32.9 ± 16.8; and 7 months after surgery it was 39.6 ± 33.2. The VAS results also proved a significant enhancement in nasal obstruction after septoplasty. Patients reported an improvement in nasal obstruction as well as a positive change in quality of life, confirming the effectiveness of septoplasty. Conclusions In patients with deformed septum, septoplasty contributes to high satisfaction of the patient and a compelling improvement in disease-specific quality of life. The NOSE-POL questionnaire is a useful tool for measuring the outcomes of this procedure.

scholarly journals Epidemiology of injuries, treatment (costs) and outcome in burn patients admitted to a hospital with or without dedicated burn centre (Burn-Pro): protocol for a multicentre prospective observational study

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e023709 ◽  
Author(s):  
Esther MM Van Lieshout ◽  
Daan T Van Yperen ◽  
Margriet E Van Baar ◽  
Suzanne Polinder ◽  
Doeke Boersma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Burn Injury ◽  
Treatment Costs ◽  
Burn Patients ◽  
Severe Burns ◽  
Referral Criteria ◽  
Age Limit

IntroductionThe Emergency Management of Severe Burns (EMSB) referral criteria have been implemented for optimal triaging of burn patients. Admission to a burn centre is indicated for patients with severe burns or with specific characteristics like older age or comorbidities. Patients not meeting these criteria can also be treated in a hospital without burn centre. Limited information is available about the organisation of care and referral of these patients. The aims of this study are to determine the burn injury characteristics, treatment (costs), quality of life and scar quality of burn patients admitted to a hospital without dedicated burn centre. These data will subsequently be compared with data from patients with<10% total bodysurface area (TBSA) burned who are admitted (or secondarily referred) to a burn centre. If admissions were in agreement with the EMSB, referral criteria will also be determined.Methods and analysisIn this multicentre, prospective, observational study (cohort study), the following two groups of patients will be followed: 1) all patients (no age limit) admitted with burn-related injuries to a hospital without a dedicated burn centre in the Southwest Netherlands or Brabant Trauma Region and 2) all patients (no age limit) with<10% TBSA burned who are primarily admitted (or secondarily referred) to the burn centre of Maasstad Hospital. Data on the burn injury characteristics (primary outcome), EMSB compliance, treatment, treatment costs and outcome will be collected from the patients’ medical files. At 3 weeks and at 3, 6 and 12 months after trauma, patients will be asked to complete the quality of life questionnaire (EuroQoL-5D), and the patient-reported part of the Patient and Observer Scar Assessment Scale (POSAS). At those time visits, the coordinating investigator or research assistant will complete the observer-reported part of the POSAS.Ethics and disseminationThis study has been exempted by the medical research ethics committee Erasmus MC (Rotterdam, The Netherlands). Each participant will provide written consent to participate and remain encoded during the study. The results of the study are planned to be published in an international, peer-reviewed journal.Trial registration numberNTR6565.

Sign in / Sign up

Export Citation Format

Share Document