scholarly journals Evaluation of the nasal microbiota in slaughter-age pigs and the impact on nasal methicillin-resistant Staphylococcus aureus (MRSA) carriage

2014 ◽  
Vol 10 (1) ◽  
pp. 69 ◽  
Author(s):  
J Weese ◽  
Mackenzie Slifierz ◽  
Mohammad Jalali ◽  
Robert Friendship
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Slaughter Age ◽  
The Impact ◽  
Nasal Microbiota

Methicillin-Resistant Staphylococcus aureus: An Emerging Pathogen in Small Animals

2005 ◽  
Vol 41 (3) ◽  
pp. 150-157 ◽  
Author(s):  
J. Scott Weese
Keyword(s):  
Staphylococcus Aureus ◽  
Disease Surveillance ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Diagnostic Testing ◽  
Small Animals ◽  
Emerging Pathogen ◽  
Methicillin Resistant ◽  
Mild Disease ◽  
Life Threatening ◽  
The Impact

Methicillin-resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen in humans and is increasingly implicated in community-associated infections in people. In household pets, MRSA infections are uncommon but are on the rise, possibly because of the increased prevalence of human MRSA in the community. Clinical MRSA infections in some animals can be life threatening and difficult to treat; however, other animals may develop mild disease or only become colonized. Veterinarians should be aware of the concerns regarding MRSA and should develop an understanding of appropriate disease surveillance, diagnostic testing, and infection control in order to lessen the impact of MRSA on small animals.

The Impact of AUC-Based Monitoring on Pharmacist-Directed Vancomycin Dose Adjustments in Complicated Methicillin-Resistant Staphylococcus aureus Infection

2018 ◽  
Vol 32 (4) ◽  
pp. 442-446 ◽  
Author(s):  
Andrew M. Stoessel ◽  
Cory M. Hale ◽  
Robert W. Seabury ◽  
Christopher D. Miller ◽  
Jeffrey M. Steele
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Area Under The Curve ◽  
Monitoring Method ◽  
Methicillin Resistant ◽  
Vancomycin Dose ◽  
Monitoring Group ◽  
Mrsa Infection ◽  
Auc Estimation ◽  
The Impact

Objective: This study aimed to assess the impact of area under the curve (AUC)-based vancomycin monitoring on pharmacist-initiated dose adjustments after transitioning from a trough-only to an AUC-based monitoring method at our institution. Methods: A retrospective cohort study of patients treated with vancomycin for complicated methicillin-resistant Staphylococcus aureus (MRSA) infection between November 2013 and December 2016 was conducted. The frequency of pharmacist-initiated dose adjustments was assessed for patients monitored via trough-only and AUC-based approaches for trough ranges: 10 to 14.9 mg/L and 15 to 20 mg/L. Results: Fifty patients were included: 36 in the trough-based monitoring and 14 in the AUC-based-monitoring group. The vancomycin dose was increased in 71.4% of patients when troughs were 10 to 14.9 mg/L when a trough-only approach was used and in only 25% of patients when using AUC estimation ( P = .048). In the AUC group, the dose was increased only when AUC/minimum inhibitory concentration (MIC) <400; unchanged regimens had an estimated AUC/MIC ≥400. The AUC-based monitoring did not significantly increase the frequency of dose reductions when trough concentrations were 15 to 20 mg/L (AUC: 33.3% vs trough: 4.6%; P = .107). Conclusions: The AUC-based monitoring resulted in fewer patients with dose adjustments when trough levels were 10 to 14.9 mg/L. The AUC-based monitoring has the potential to reduce unnecessary vancomycin exposure and warrants further investigation.

The impact of methicillin-resistant Staphylococcus aureus on ENT practice

2006 ◽  
Vol 120 (9) ◽  
pp. 713-717 ◽  
Author(s):  
I J Nixon ◽  
B J G Bingham
Keyword(s):  
Staphylococcus Aureus ◽  
Infection Control ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistance ◽  
Resistant Bacteria ◽  
Antibiotic Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Methicillin Resistant ◽  
The Impact

Antibiotic-resistant bacteria are increasingly common and present a major problem for the modern day ENT surgeon. This article reviews the development of methicillin resistance in Staphylococcus aureus and how it has come to affect ENT practice. We look at the evidence behind measures taken to help deal with methicillin-resistant Staphylococcus aureus (MRSA) and to prevent its spread. We go on to suggest a departmental guideline for infection control, which we hope can be implemented to help deal with the problems created by MRSA.

Sign in / Sign up

Export Citation Format

Share Document