scholarly journals Recent progress of graphene oxide-based multifunctional nanomaterials for cancer treatment

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Lijun Liu ◽  
Qingming Ma ◽  
Jie Cao ◽  
Yang Gao ◽  
Shangcong Han ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Cancer Treatment ◽  
Recent Progress ◽  
High Surface ◽  
High Surface Area ◽  
Antitumor Therapy ◽  
Reduced Graphene ◽  
Potential Applications ◽  
Multifunctional Nanomaterials ◽  
Biomolecules Detection

Abstract Background In the last decade, graphene oxide-based nanomaterials, such as graphene oxide (GO) and reduced graphene oxide (rGO), have attracted more and more attention in the field of biomedicine. Due to the versatile surface functionalization, ultra-high surface area, and excellent biocompatibility of graphene oxide-based nanomaterials, which hold better promise for potential applications than among other nanomaterials in biomedical fields including drug/gene delivery, biomolecules detection, tissue engineering, especially in cancer treatment. Results Here, we review the recent progress of graphene oxide-based multifunctional nanomaterials for cancer treatment. A comprehensive and in-depth depiction of unique property of graphene oxide-based multifunctional nanomaterials is first interpreted, with particular descriptions about the suitability for applying in cancer therapy. Afterward, recently emerging representative applications of graphene oxide-based multifunctional nanomaterials in antitumor therapy, including as an ideal carrier for drugs/genes, phototherapy, and bioimaging, are systematically summarized. Then, the biosafety of the graphene oxide-based multifunctional nanomaterials is reviewed. Conclusions Finally, the conclusions and perspectives on further advancing the graphene oxide-based multifunctional nanomaterials toward potential and versatile development for fundamental researches and nanomedicine are proposed. Graphic abstract

A one-step electrochemically reduced graphene oxide based sensor for sensitive voltammetric determination of furfural in milk products

2021 ◽  
Vol 13 (1) ◽  
pp. 56-63
Author(s):  
Qiuqiu Wang ◽  
Juanhua Zhang ◽  
Yanbo Xu ◽  
Yingyi Wang ◽  
Liang Wu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
High Surface ◽  
High Surface Area ◽  
Milk Products ◽  
Reduced Graphene ◽  
Electrochemically Reduced Graphene Oxide ◽  
One Step ◽  
Dairy Milk

One-step electrochemically reduced graphene oxide with high surface area and improved electron transfer kinetics shows great performances in the determination of furfural in dairy milk.

scholarly journals Graphene-Based Nanomaterials for Theranostic Applications

2017 ◽  
Vol 01 (04) ◽  
pp. 1750011 ◽  
Author(s):  
Shounak Roy ◽  
Amit Jaiswal
Keyword(s):  
Graphene Oxide ◽  
High Surface ◽  
Graphene Quantum Dots ◽  
High Surface Area ◽  
Nucleic Acid Delivery ◽  
Efficient Detection ◽  
Reduced Graphene ◽  
Theranostic Applications

Graphene and graphene-based nanomaterials such as graphene oxide (GO), reduced graphene oxide (rGO) and graphene quantum dots (GQDs) have gained a lot of attention from diverse scientific fields for applications in sensing, catalysis, nanoelectronics, material engineering, energy storage and biomedicine due to its unique structural, optical, electrical and mechanical properties. Graphene-based nanomaterials emerge as a novel class of nanomedicine for cancer therapy for several reasons. Firstly, its structural properties like high surface area and aromaticity enables easy loading of hydrophobic drugs. Secondly, presence of oxygen containing functional groups improve its physiological stability and also act as site for biofunctionalization. Thirdly, its optical absorption in the NIR region enable them to act as photoagents for photothermal and photodynamic therapies of cancer, both in vitro and in vivo. Finally, its intrinsic fluorescence property helps in bioimaging of cancer cells. Overall, graphene-based nanomaterials can act as agents for developing multifunctional theranostic platforms for carrying out more efficient detection and treatment of cancers. This review provides a detailed summary of the different applications of graphene-based nanomaterials in drug delivery, nucleic acid delivery, phototherapy, bioimaging and theranostics.

scholarly journals Graphene: A Versatile Carbon-Based Material for Bone Tissue Engineering

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Nileshkumar Dubey ◽  
Ricardo Bentini ◽  
Intekhab Islam ◽  
Tong Cao ◽  
Antonio Helio Castro Neto ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Stem Cell ◽  
Cell Attachment ◽  
High Surface ◽  
High Surface Area ◽  
Reduced Graphene ◽  
Proliferation And Differentiation ◽  
Cell Growth And Differentiation ◽  
Large Bone ◽  
Carbon Based

The development of materials and strategies that can influence stem cell attachment, proliferation, and differentiation towards osteoblasts is of high interest to promote faster healing and reconstructions of large bone defects. Graphene and its derivatives (graphene oxide and reduced graphene oxide) have received increasing attention for biomedical applications as they present remarkable properties such as high surface area, high mechanical strength, and ease of functionalization. These biocompatible carbon-based materials can induce and sustain stem cell growth and differentiation into various lineages. Furthermore, graphene has the ability to promote and enhance osteogenic differentiation making it an interesting material for bone regeneration research. This paper will review the important advances in the ability of graphene and its related forms to induce stem cells differentiation into osteogenic lineages.

scholarly journals High-Surface-Area Nitrogen-Doped Reduced Graphene Oxide for Electric Double-Layer Capacitors

ChemSusChem ◽  
2015 ◽  
Vol 8 (11) ◽  
pp. 1875-1884 ◽  
Author(s):  
Hee-Chang Youn ◽  
Seong-Min Bak ◽  
Myeong-Seong Kim ◽  
Cherno Jaye ◽  
Daniel A. Fischer ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Surface Area ◽  
Double Layer ◽  
Electric Double Layer ◽  
High Surface ◽  
High Surface Area ◽  
Nitrogen Doped ◽  
Reduced Graphene ◽  
Double Layer Capacitors

scholarly journals Detection of Microorganisms Using Graphene-Based Nanobiosensors

2021 ◽  
Vol 59 (4) ◽  
Author(s):  
Mehrab Pourmadadi ◽  
Fatemeh Yazdian ◽  
Sara Hojjati ◽  
Kianoush Khosravi-Darani
Keyword(s):  
Graphene Oxide ◽  
Electrochemical Behavior ◽  
High Surface ◽  
Graphene Quantum Dots ◽  
High Surface Area ◽  
Bacterial Cells ◽  
Design Strategies ◽  
Reduced Graphene ◽  
Graphene Derivatives ◽  
High Elasticity

Having an insight into graphene and graphene derivatives such as graphene oxide, reduced graphene oxide, and graphene quantum dots structures is necessary since it can help scientists to suspect the possible properties and features that using these carbon materials in preparation of a nanocomposite could bring out. In recent years, graphene and its derivatives are attractive with extensive applications in biosensors due to fascinating properties, such as high surface area, optical and magnetic properties, and high elasticity for the detection of microorganisms can be modified with some other materials such as macromolecules, oxide metals, and metals to improve the electrochemical behavior of the biosensor, and also can be modified with some other materials such as macromolecules, oxide metals, and metals to improve the electrochemical behavior of the biosensor. In this review paper, biosensors design strategies based on graphene and its derivatives (graphene-based nanocomposites in biosensors) are introduced. Then their application for the detection of microorganisms including Prions, Viroids, viral and bacterial cells as well as fungi, protozoa, microbial toxins, and even microbial-derived antibiotics are reviewed.

Inside Cover: High-Surface-Area Nitrogen-Doped Reduced Graphene Oxide for Electric Double-Layer Capacitors (ChemSusChem 11/2015)

ChemSusChem ◽  
2015 ◽  
Vol 8 (11) ◽  
pp. 1822-1822
Author(s):  
Hee-Chang Youn ◽  
Seong-Min Bak ◽  
Myeong-Seong Kim ◽  
Cherno Jaye ◽  
Daniel A. Fischer ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Surface Area ◽  
Double Layer ◽  
Electric Double Layer ◽  
High Surface ◽  
High Surface Area ◽  
Nitrogen Doped ◽  
Reduced Graphene ◽  
Double Layer Capacitors
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