scholarly journals Delays to anti-tuberculosis treatment intiation among cases on directly observed treatment short course in districts of southwestern Ethiopia: a cross sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Abyot Asres ◽  
Degu Jerene ◽  
Wakgari Deressa
Keyword(s):  
Cross Sectional Study ◽  
Tuberculosis Treatment ◽  
Sectional Study ◽  
Cross Sectional ◽  
Southwestern Ethiopia ◽  
Short Course ◽  
Directly Observed Treatment

scholarly journals Socio-demographic determinants of tuberculosis patients attending directly observed treatment short course centre in urban Ghaziabad, Uttar Pradesh

2020 ◽  
Vol 7 (5) ◽  
pp. 1756
Author(s):  
Manoj Kumar Yadav ◽  
Mohit Raghav ◽  
S. S. Chaudhary ◽  
Manisha .
Keyword(s):  
Nuclear Family ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Short Course ◽  
Directly Observed Treatment ◽  
Multistage Sampling

Background: Tuberculosis was the first infectious disease declared by the WHO as a global health emergency. Men are more commonly affected than women. The case notifications were higher in males than in females most countries. The objective of the study was to assess socio-demographic determinants of tuberculosis patients attending directly observed treatment short course (DOTS) centre in Urban Ghaziabad.Methods: This was an observational cross-sectional study. The study was carried out in selected DOTS centres of district Ghaziabad. 850 study subjects age group more than 15 years were included.  Multistage sampling was done. Numbers and percentage were used. SPSS version 13 was used for statistical analysis.Results: Majority 41.17% of tuberculosis (TB) patients belonged to 15-25 years age group. 30.58% patients were in 26-35 years age group followed by 23.52% in 36-45 years age group and least 4.70% were in >45 years age group. Majority 54.1% of TB patients were females that compared to 45.9% were males. Among tuberculosis patients majority 58.82% were married as compared to 40% were unmarried and least 1.18% were widow. 75.29% tuberculosis patients were Hindus as compared to 22.35 were Muslims and least 2.35% were Sikh/Christian. Among tuberculosis patients majority 44.71% were from nuclear family. 31.76% had joint family and least 23.53% had 3rd generation family.Conclusions: It was concluded that socio-demographic determinants were low. It was recommended to raise socioeconomic standard of population, give health education to improve personal habit and stop TB transmission. 

scholarly journals Multimorbidity among Tuberculosis Cases’ Bangladesh Perspective

2019 ◽  
Vol 46 (3) ◽  
pp. 74-79 ◽  
Author(s):  
Atiya Tasnim Muna ◽  
Kazi Shafiqul Halim ◽  
Bushra E Zannat Khan ◽  
Kazi Fardana Mostary ◽  
Md Safikul Islam ◽  
...  
Keyword(s):  
Chronic Conditions ◽  
Family Income ◽  
Cross Sectional Study ◽  
Multiple Chronic Conditions ◽  
Chronic Medical Conditions ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Short Course ◽  
Directly Observed Treatment

Globally tuberculosis (TB) has become the leading cause of death from infectious diseases. Tuberculosis is a chronic infection and a person may suffer from tuberculosis and other chronic medical conditions at the same time. Co-occurrence of multiple chronic conditions in the same individual, known as multimorbidity (MM) is increasing worldwide. This cross-sectional study was carried out from January 2017 to December 2017 to reveal the extent of multimorbidity among tuberculosis cases. A TB case with multimorbidity was defined as TB with multimorbidity (TB-MM) subject. By convenient sampling, 227 tuberculosis cases from 8 Directly Observed Treatment, Short Course (DOTS) centers from Dhaka, Mymensingh and Netrokona districts were enrolled in this study. Among 227 tuberculosis cases 29 (12.8%) cases had multimorbidity (TB-MM subjects). Prevalence of multimorbidity was significantly higher in age group ≥40 years (p<0.001), male cases (p=0.034) and cases who had family income >30000 BDT/month (p=0.001), were currently smoker (p=0.028) and whose BCG scars were not seen (p<0.001). This study recommends that each TB case should be investigated for other chronic conditions to reveal the actual national magnitude of multimorbidity. Bangladesh Med J. 2017 Sep; 46 (3): 74-79

scholarly journals Adverse drug reactions in patients taking anti tuberculosis therapy from directly observed treatment short course centre at Mandya Institute of Medical Sciences, Mandya: a cross sectional study

2020 ◽  
Vol 7 (2) ◽  
pp. 620
Author(s):  
Shambhulinga Kambale ◽  
P. Subhas Babu ◽  
Nagaraja Goud B. ◽  
Harish B. R.
Keyword(s):  
Adverse Drug Reactions ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Drug Reactions ◽  
Chi Square ◽  
Cross Sectional ◽  
Short Course ◽  
Directly Observed Treatment ◽  
Compliance To Treatment ◽  
Anti Tubercular Therapy

Background: Ending the tuberculosis (TB) epidemic by 2030 is among the health targets of the sustainable development goals. Side effects to anti-TB drugs are common and may lead to reduced compliance to treatment. These adverse effects must be recognized early to reduce associated morbidity and mortality. Objective of this study was to determine the adverse drug reactions (ADR) to anti-tubercular therapy among patients visiting directly observed treatment, short-course (DOTS) centre MIMS, Mandya.Methods: A cross sectional study was conducted at DOTS Centre MIMS, Mandya. TB patients registered at DOTS Centre during the year 2018 were selected for the study. Verbal informed consent was taken from the TB patients and interviewed using pretested semi-structured questionnaire. Data analysis was done using descriptive statistics and chi square test.Results: Among the study population (n=90), 67 (74.4%) experienced ADR among which 47.7% took treatment for ADR and the remaining 52.3% patients were given reassurance. In this study, gastrointestinal manifestations (42.3%) were the most common adverse drug reaction (ADR). Of the TB patients who experienced ADR, 9.0% of them had interrupted ATT, however they completed full course of ATT.Conclusions: A considerable number of TB patients taking ATT experience ADRs and some of them may have to interrupt treatment. However, they need to be counselled or supervised with caution to complete their course of treatment to reduce the chances of treatment default and also reduce the occurrence of drug resistance.

scholarly journals Nonadherence to tuberculosis treatment and associated factors among patients using directly observed treatment short-course in north-west Nigeria: A cross-sectional study

2021 ◽  
Vol 9 ◽  
pp. 205031212198949
Author(s):  
Cylia Nkechi Iweama ◽  
Olaoluwa Samson Agbaje ◽  
Prince Christian Ifeanachor Umoke ◽  
Chima Charles Igbokwe ◽  
Eyuche Lawretta Ozoemena ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Cross Sectional Study ◽  
Medication Nonadherence ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
North West ◽  
Short Course ◽  
Directly Observed Treatment

Introduction: Tuberculosis is a public health problem in Nigeria. One of the most effective ways of controlling tuberculosis is the directly observed treatment short-course. However, some factors influence tuberculosis patients’ treatment nonadherence via directly observed treatment short-course. The study objective was to assess medication nonadherence and associated factors among tuberculosis patients in north-west Nigeria. Methods: A cross-sectional study enrolled tuberculosis patients using directly observed treatment short-course in public health facilities in Kano and Kaduna States from January 2015 to June 2016. The sample selection was conducted via a multistage sampling procedure. Data were collected using tuberculosis patients’ demographic and clinical characteristics forms, well-validated structured instruments, and medical records. SPSS version 20 was used for data analysis. Logistic and multivariable logistic regression analyses to determine factors of medication nonadherence ( P < 0.05) Results: Complete responses from 390 patients out of the 460 patients recruited for the study were used for data analyses. The mean age was 51.5 (standard deviation = ±13.8) years. The mean tuberculosis medication adherence questionnaire score was 4.35 ± 1.12. The prevalence of nonadherence to tuberculosis medication was 30.5%. Multivariable logistic regression analysis showed that having a monthly income between #100,000 and #199, 000 (adjusted odds ratio = 0.01; 95% confidence interval: 0.00–0.13), being widowed (adjusted odds ratio = 26.74, 95% confidence interval: 2.92–232.9), being married (adjusted odds ratio = 120.49, 95% confidence interval: 5.38–271.1), having a distance <5 km to directly observed treatment short-course center from home (adjusted odds ratio = 0.06, 95% confidence interval: 0.00–0.01), having a tuberculosis/HIV co-infection (adjusted odds ratio = 0.01, 95% confidence interval: 0.12–0.35), use of antiretroviral treatment and cotrimoxazole prophylaxis therapy medications (adjusted odds ratio = 24.9, 95% confidence interval: 19.6–304.3) were associated with tuberculosis medication nonadherence. Conclusion: Tuberculosis medication nonadherence was high among the patients. Thus, patient-specific adherence education, attenuation of potential factors for tuberculosis medication nonadherence, and continual resource support for tuberculosis patients are needed to improve treatment outcomes.

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