Using a hepatitis B surveillance system evaluation in Fujian, Hainan, and Gansu provinces to improve data quality and assess program effectiveness, China, 2015

Abstract Background: Monitoring hepatitis B surveillance data is important for evaluating progress towards global hepatitis B elimination goals. Accurate classification of acute and chronic hepatitis infections is essential for assessing program effectiveness. Methods: We evaluated hepatitis B case-reporting at six hospitals in Fujian, Hainan and Gansu provinces in 2015 to assess the accuracy of case classification. We linked National Notifiable Disease Reporting System (NNDRS) HBV case-reports with hospital information systems and extracted information on age, gender, admission ward and viral hepatitis diagnosis from medical records. To assess accuracy, we compared NNDRS reported case-classifications with the national HBV case definitions. Multivariable logistic regression was used to identify factors associated with misclassification. Results: Of the 1,420 HBV cases reported to NNDRS, 23 (6.5%) of the 352 acute reports and 648 (60.7%) of the 1,068 chronic reports were correctly classified. Of the remaining, 318 (22.4%) were misclassified and 431 (30.4%) could not be classified due to the lack of supporting information. Based on the multivariable analysis, HBV cases reported from Hainan (aOR=1.8; 95% CI: 1.3-2.4) and Gansu (aOR=12.7; 95% CI: 7.7-20.1) along with reports from grade 2 hospitals (aOR=1.6; 95% CI:1.2-2.2) and those from non-HBV related departments (aOR=5.3; 95% CI: 4.1-7.0) were independently associated with being ‘misclassified’ in NNDRS. Conclusions: We identified discrepancies in the accuracy of HBV case-reporting in the project hospitals. Onsite training on the use of anti-HBc IgM testing as well as on HBV case definitions and reporting procedures are needed to accurately assess program effectiveness and ensure case-patients are referred to appropriate treatment and care. Routine surveillance evaluations such as this can be useful for improving data quality and monitoring program effectiveness.

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Using a Hepatitis B surveillance system evaluation in Fujian, Hainan, and Gansu Provinces to improve data quality and assess program effectiveness, China, 2015

10.21203/rs.2.9646/v2 ◽

2019 ◽

Author(s):

Hui Zheng ◽

Alexander J. Millman ◽

Jeanette J. Rainey ◽

Fuzhen Wang ◽

Rui Zhang ◽

...

Keyword(s):

Hepatitis B ◽

Data Quality ◽

Program Effectiveness ◽

Case Reports ◽

Multivariable Analysis ◽

Monitoring Program ◽

Case Definitions ◽

Admission Ward ◽

Appropriate Treatment ◽

Routine Surveillance

Abstract Background: Monitoring hepatitis B surveillance data is important for evaluating progress towards global hepatitis B elimination goals. Accurate classification of acute and chronic hepatitis infections is essential for assessing program effectiveness. Methods: We evaluated hepatitis B case-reporting at six hospitals in Fujian, Hainan and Gansu provinces in 2015 to assess the accuracy of case classification. We linked National Notifiable Disease Reporting System (NNDRS) HBV case-reports with hospital information systems and extracted information on age, gender, admission ward and viral hepatitis diagnosis from medical records. To assess accuracy, we compared NNDRS reported case-classifications with the national HBV case definitions. Multivariable logistic regression was used to identify factors associated with misclassification. Results: Of the 1,420 HBV cases reported to NNDRS, 23 (6.5%) of the 352 acute reports and 648 (60.7%) of the 1,068 chronic reports were correctly classified. Of the remaining, 318 (22.4%) were misclassified and 431 (30.4%) could not be classified due to the lack of supporting information. Based on the multivariable analysis, HBV cases reported from Hainan (aOR=1.8; 95% CI: 1.3-2.4) and Gansu (aOR=12.7; 95% CI: 7.7-20.1) along with reports from grade 2 hospitals (aOR=1.6; 95% CI:1.2-2.2) and those from non-HBV related departments (aOR=5.3; 95% CI: 4.1-7.0) were independently associated with being ‘misclassified’ in NNDRS. Conclusions: We identified discrepancies in the accuracy of HBV case-reporting in the project hospitals. Onsite training on the use of anti-HBc IgM testing as well as on HBV case definitions and reporting procedures are needed to accurately assess program effectiveness and ensure case-patients are referred to appropriate treatment and care. Routine surveillance evaluations such as this can be useful for improving data quality and monitoring program effectiveness.

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Using a Hepatitis B surveillance system evaluation in Fujian, Hainan, and Gansu Provinces to improve data quality and assess program effectiveness, China, 2015

10.21203/rs.2.9646/v4 ◽

2020 ◽

Author(s):

Hui Zheng ◽

Alexander J. Millman ◽

Jeanette J. Rainey ◽

Fuzhen Wang ◽

Rui Zhang ◽

...

Keyword(s):

Hepatitis B ◽

Data Quality ◽

Program Effectiveness ◽

Case Reports ◽

Multivariable Analysis ◽

Monitoring Program ◽

Case Definitions ◽

Admission Ward ◽

Appropriate Treatment ◽

Routine Surveillance

Abstract Background: Monitoring hepatitis B surveillance data is important for evaluating progress towards global hepatitis B elimination goals. Accurate classification of acute and chronic hepatitis infections is essential for assessing program effectiveness. Methods: We evaluated hepatitis B case-reporting at six hospitals in Fujian, Hainan and Gansu provinces in 2015 to assess the accuracy of case classification. We linked National Notifiable Disease Reporting System (NNDRS) HBV case-reports with hospital information systems and extracted information on age, gender, admission ward and viral hepatitis diagnosis from medical records. To assess accuracy, we compared NNDRS reported case-classifications with the national HBV case definitions. Multivariable logistic regression was used to identify factors associated with misclassification. Results: Of the 1,420 HBV cases reported to NNDRS, 23 (6.5%) of the 352 acute reports and 648 (60.7%) of the 1,068 chronic reports were correctly classified. Of the remaining, 318 (22.4%) were misclassified and 431 (30.4%) could not be classified due to the lack of supporting information. Based on the multivariable analysis, HBV cases reported from Hainan (aOR=1.8; 95% CI: 1.3-2.4) and Gansu (aOR=12.7; 95% CI: 7.7-20.1) along with reports from grade 2 hospitals (aOR=1.6; 95% CI:1.2-2.2) and those from non-HBV related departments (aOR=5.3; 95% CI: 4.1-7.0) were independently associated with being ‘misclassified’ in NNDRS. Conclusions: We identified discrepancies in the accuracy of HBV case-reporting in the project hospitals. Onsite training on the use of anti-HBc IgM testing as well as on HBV case definitions and reporting procedures are needed to accurately assess program effectiveness and ensure case-patients are referred to appropriate treatment and care. Routine surveillance evaluations such as this can be useful for improving data quality and monitoring program effectiveness.

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Using a Hepatitis B surveillance system evaluation in Fujian, Hainan, and Gansu Provinces to improve data quality and assess program effectiveness, China, 2015

10.21203/rs.2.9646/v1 ◽

2019 ◽

Author(s):

Hui Zheng ◽

Alexander J. Millman ◽

Jeanette J. Rainey ◽

Fuzhen Wang ◽

Rui Zhang ◽

...

Keyword(s):

Hepatitis B ◽

Data Quality ◽

Program Effectiveness ◽

Case Reports ◽

Multivariable Analysis ◽

Monitoring Program ◽

Case Definitions ◽

Appropriate Treatment ◽

Routine Surveillance ◽

Report System

Abstract Abstract Background: Monitoring hepatitis B surveillance data is important for evaluating progress towards global hepatitis B elimination goals. Accurate classification of acute and chronic hepatitis infections is essential for assessing program effectiveness. Methods: We evaluated hepatitis B case-reporting at six hospitals in Fujian, Hainan and Gansu provinces in 2015 to assess the accuracy of case classification. We linked national notifiable disease report system (NNDRS) HBV case-reports with hospital information systems and extracted information on age, gender, admitting ward and viral hepatitis diagnosis from medical records. To assess accuracy, we compared NNDRS reported case-classifications with the national HBV case definitions. Multivariable logistic regression was used to identify factors associated with misclassification. Results: Of the 1,420 HBV cases reported to NNDRS, 23 (6.5%) of the 352 acute reports and 648 (60.7%) of the 1,068 chronic reports were correctly classified. Of the remaining, 318 (22.4%) were misclassified and 431 (30.4%) could not be classified due to the lack of supporting information. According to the multivariable analysis, HBV cases reported from Hainan (aOR=1.8; 95% CI: 1.3-2.4) and Gansu (aOR=12.7; 95% CI: 7.7-20.1) along with reports from grade 2 hospitals (aOR=1.6; 95% CI:1.2-2.2) and those from non-HBV related departments (aOR=5.3; 95% CI: 4.1-7.0) were independently associated with being ‘misclassified’ in NNDRS. Conclusions: We identified discrepancies in the accuracy of HBV case-reporting in the project hospitals. Onsite training on the use of anti-HBc IgM testing as well as on HBV case definitions and reporting procedures are needed to accurately assess program effectiveness and ensure case-patients are referred to appropriate treatment and care. Routine surveillance evaluations such as this can be useful for improving data quality and monitoring program effectiveness.

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Correction to: Using a hepatitis B surveillance system evaluation in Fujian, Hainan, and Gansu provinces to improve data quality and assess program effectiveness, China, 2015

BMC Infectious Diseases ◽

10.1186/s12879-020-05708-x ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Hui Zheng ◽

Alexander J. Millman ◽

Jeanette J. Rainey ◽

Fuzhen Wang ◽

Rui Zhang ◽

...

Keyword(s):

Hepatitis B ◽

Data Quality ◽

Surveillance System ◽

Program Effectiveness ◽

System Evaluation ◽

Improve Data Quality ◽

Surveillance System Evaluation

An amendment to this paper has been published and can be accessed via the original article.

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Role of Radiotherapy in Recurrent Intra-Abdominal Yolk Sac Tumor

Case Reports in Oncology ◽

10.1159/000517022 ◽

2021 ◽

pp. 1010-1018

Author(s):

Marhendra Satria Utama ◽

Andi Kurniadi ◽

A.A. Citra Yunda Prahastiwi ◽

Antony A. Adibrata

Keyword(s):

Case Reports ◽

Yolk Sac ◽

Yolk Sac Tumor ◽

Appropriate Treatment ◽

Curative Radiotherapy ◽

Chief Complaints ◽

Abdominal Mri ◽

Malignant Germ Cell Tumor

Yolk sac tumor (YST) is a rare malignant germ cell tumor with no appropriate treatment strategy to date. However, patients are treated on a case-to-case basis as per various case reports that have been published. Here, we present a case of 27-year-old female patient who presented to us with chief complaints of severe abdominal pain associated with leucorrhea. She previously had a similar pain episode, which was then evaluated by a multidisciplinary team. She was diagnosed with YST. After that, she underwent 6 cycles of chemotherapy, but there was no improvement. Then the medical oncologist referred her to performed radiotherapy. Then, the radiation oncologist decided to give her curative radiotherapy of 3D-CRT. After completing her sessions, she felt better and clinically improving. After that, she was discharged and scheduled a follow-up visit for first evaluation. At her follow-up visit, she was feeling well, and we decided to have an abdominal MRI.

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Author self-citation in orthodontics is associated with author origin and gender

Progress in Orthodontics ◽

10.1186/s40510-020-00348-y ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Christos Livas ◽

Konstantina Delli ◽

Nikolaos Pandis

Keyword(s):

Negative Binomial ◽

Case Reports ◽

Citation Rate ◽

Multivariable Analysis ◽

Negative Binomial Regression ◽

Original Research ◽

Journal Citation Reports ◽

Citation Counts ◽

And Gender ◽

Study Type

Abstract Background The aims of this bibliometric study were to determine author self-citation trends in high-impact orthodontic literature and to investigate possible association between self-citation and publication characteristics. Methods Six orthodontic journals with the highest impact factor as ranked by 2017 Journal Citation Reports were screened for a full publication year (2018) for original research articles, reviews, and case reports. Eligible articles were scrutinized for article and author characteristics and citation metrics. Univariable and multivariable negative binomial regression was used to examine associations between self-citation incidence and publication characteristics. Results Medians for author self-citation rate of the most self-citing authors and self-citations were 3.03% (range 0–50) and 1 (range 0–19), respectively. In the univariable analysis, there was no association between self-citation counts and study type (P = 0.41), article topic (P = 0.61), number of authors (P = 0.62), and rank of authors (P = 0.56). Author origin (P = 0.001), gender (P = 0.001) and journal (P = 0.05) were associated with self-citation counts and in the multivariable analysis only origin and gender remained strong self-citation predictors. Asian authors and females self-cited significantly less often than all other regions and male authors. Conclusions Authors in orthodontics do not self-cite at a frequency that suggests potential citation manipulation. Author origin and gender were the only variables associated with citations counts. More bibliometric research is necessary to draw solid conclusions about author self-citation trends in orthodontic literature.

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A New Automatic Monitoring Network of Surface Waters in Greece: Preliminary Data Quality Checks and Visualization

Hydrology ◽

10.3390/hydrology8010033 ◽

2021 ◽

Vol 8 (1) ◽

pp. 33

Author(s):

Yiannis Panagopoulos ◽

Anna Konstantinidou ◽

Konstantinos Lazogiannis ◽

Anastasios Papadopoulos ◽

Elias Dimitriou

Keyword(s):

Data Quality ◽

Surface Waters ◽

Data Dissemination ◽

Monitoring Program ◽

Monitoring Network ◽

Automatic Monitoring ◽

Water Monitoring ◽

Marine Research ◽

Management Actions ◽

Quality Checks

The monitoring of surface waters is of fundamental importance for their preservation under good quantitative and qualitative conditions, as it can facilitate the understanding of the actual status of water and indicate suitable management actions. Taking advantage of the experience gained from the coordination of the national water monitoring program in Greece and the available funding from two ongoing infrastructure projects, the Institute of Inland Waters of the Hellenic Centre for Marine Research has developed the first homogeneous real-time network of automatic water monitoring across many Greek rivers. In this paper, its installation and maintenance procedures are presented with emphasis on the data quality checks, based on values range and variability tests, before their online publication and dissemination to end-users. Preliminary analyses revealed that the water pH and dissolved oxygen (DO) sensors and produced data need increased maintenance and quality checks respectively, compared to the more reliably recorded water stage, temperature (T) and electrical conductivity (EC). Moreover, the data dissemination platform and selected data visualization options are demonstrated and the need for both this platform and the monitoring network to be maintained and potentially expanded after the termination of the funding projects is highlighted.

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Surveillance for Transmission of Hepatitis B in Child Day Care

PEDIATRICS ◽

10.1542/peds.94.6.1002 ◽

1994 ◽

Vol 94 (6) ◽

pp. 1002-1004

Author(s):

Hjordis M. Foy ◽

Paul D. Swenson ◽

M. Jayne Freitag-Koontz ◽

Janice Boase ◽

Tianji-Yu ◽

...

Keyword(s):

Hepatitis B ◽

Day Care ◽

Case Reports ◽

Hepatitis B Surface Antigen ◽

Horizontal Transmission ◽

Acute Infection ◽

Venous Blood ◽

Core Antigen ◽

Day Care Centers ◽

Blood Specimens

Relatively little is known about the risk of transmission of hepatitis B virus (HBV) in day-care centers; the virus is primarily spread by blood and other body secretions. Gradual horizontal transmission of hepatitis B has been observed in homes for the mentally retarded.1-3 Horizontal spread in children appears to be of equal importance with vertical transmission in countries where hepatitis B is endemic.4 These infections, which usually are asymptomatic, may result in chronic carriage and may go undetected unless children are tested for hepatitis B markers. Studies in day-care centers in Okinawa, where HBV carriage is relatively common, suggest that transmission may occur in day-care centers.5 Case reports of HBV transmission in school or day-care settings in the US6 and Italy7 have been published. Our study was undertaken to determine whether there is evidence of horizontal transmission of HBV infections in US day-care facilities. To evaluate this, we screened for the antibody to hepatitis B core antigen (anti-HBc), a marker which is seen both in those who have recovered from hepatitis B and those who are carriers.8 Capillary blood specimens, obtained by finger prick, were used. Children who tested positive had venous blood specimens drawn and their families were approached for consent to draw venous specimens also from the household members to evaluate if the infection may have originated in the family. The venous specimens were tested also for additional markers, especially for hepatitis B surface antigen (HBsAg), which is found during acute infection and in carriers, and antibody to HBsAg (anti-HBs) which develops after infection and immunization.

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Use of Particulated Juvenile Articular Cartilage Allograft for Osteochondral Lesions of the Wrist

Hand ◽

10.1177/1558944716673047 ◽

2016 ◽

Vol 12 (5) ◽

pp. NP62-NP67 ◽

Cited By ~ 3

Author(s):

Daniel E. Hess ◽

Brian C. Werner ◽

D. Nicole Deal

Keyword(s):

Articular Cartilage ◽

Case Reports ◽

New Technology ◽

Full Range ◽

Osteochondral Lesions ◽

Appropriate Treatment ◽

Cartilage Injuries ◽

Articular Cartilage Injuries ◽

Outerbridge Grade ◽

Active Patients

Background: Articular cartilage injuries are a common injury among young, active patients, and the most appropriate treatment for these injuries remains controversial. A promising new technology in the treatment of high-grade cartilage injuries is particulated juvenile articular cartilage (PJAC) allograft (DeNovo NT, Zimmer, Warsaw, Indiana). This has been shown to be successful in multiple joints including the knee, talus, and elbow. No studies or case reports exist in supporting or discouraging its use in injuries of the wrist, in specific, the scaphoid. Methods: The use of PJAC allograft is described for the treatment of an active 21-year-old male with an Outerbridge Grade IV chondral lesion on the proximal pole of his right scaphoid and right distal radius scaphoid facet who had failed conservative management. The patient was followed clinically and radiographically for 21 months. Results: The patient had return to full sport (jujutsu) and full range-of-motion, both of which represented an improvement from his preoperative exam. Radiographically, the chondral lucency seen had decreased in size and was almost completely absent on radiographs after 21 months. Conclusions: The results of this case suggest that PJAC can be used safely and effectively in the wrist thereby potentially broadening the indications for its use.

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