E-Report System to Help Monitor Student Academic Progress Using Forward Chaining for Grade Promotion According to Student Development Level

The COVID-19 pandemic that has occurred in the world and Indonesia is one of the affected countries. To limit the rate of transmission of COVID-19, the Ministry of Education issued regulations relating to online schools. With this online school, both parents and teachers need media to be able to monitor students' academic progress as long as online schools are implemented. Therefore, we need a system that can assist teachers and parents in monitoring students' academic progress. In this study, an e-report was designed by incorporating the components of students' academic aspect and students' character aspect. This system is supported by a decision support system using forward chaining to determine the feasibility of a grade increase according to the level of development of the student. The output of this system is student grade reports, advice given to parents and grade promotion decisions based on academic and character aspect.

A New Legal Design for the Credit Reporting Industry

Under the traditional and well-established conception, credit bureaus are understood as being little more than vessels storing customer data that has been furnished by specific suppliers, such as banks, intermediaries and, more generally, lenders. Accordingly, credit bureaus are deemed to play a ‘neutral’ role in the credit market. Hence, in Europe and the US, they are generally not responsible for any inaccuracies in the information they put into circulation, despite data quality being crucial for the proper functioning of the market and for a fair allocation of resources. This circumstance engenders, however, a conflict between the market interest in accurate data and the ‘endogenous’ for-profit interest of credit bureaus. More specifically, despite their performing an important activity in an oligopolistic environment, credit bureaus are presently allowed to pursue their for-profit interest without any substantial accountability as regards their ‘exogenous’ function of transmitting accurate data. This disequilibrium oftentimes results in under-performance and a low level of data quality. The analysis points out, also through a comparative analysis with the rules governing the US credit report system, how these circumstances in the credit market sector can imperil some pivotal objectives of the EU legal policy, which aims at ensuring equal levels of protection among citizens of Member States within a unique environment dependent on the cross-border exchange of information.

280 Descriptive Characteristics of Preweaned Heifer Raising Practices on China Dairy Farms: Colostrum Quality, Passive Transfer Status and Growth Performance

Few data are available on the descriptive characteristics of colostrum quality, passive transfer status and growth performance within a national population in China. This study included 110 dairy operations in 23 provinces, and data were obtained from management software, report system and questionnaires from 2015 to 2019. Data were analyzed using SAS (version 9.0, SAS Institute Inc., Cary, NC, USA). The results showed that colostrum quality was measured in 96.4% of farms and colostrum was pasteurized in 91.8% of farms. 83.6% of colostrum was excellent (Brix > 22%). Colostrum could be fed to calves within 1 hour after birth in 86.4% of farms. Besides, calves that experienced failure of passive transfer (serum total protein < 5.2 g/dl) decreased from 2015 to 2019 and accounted for 0.75% of calves in 2019. Most farms (48.8%) feed 400 kg - 600 kg milk during the preweaning period and whole milk was the main type of liquid diet accounting for 70.6% of farms. Meanwhile, 22.0% of farms chose to feed forage before weaning, and 90.1% of these farms fed oat hay. The average birth weight of calves was 37.8 kg and the average daily gain of preweaning calves was 848.3 g/d. For preweaning calves, the proportion of single housing was more than 60%, whereas postweaning calves were mainly raised in groups. The morbidity of preweaning calves in China decreased annually, from 43.3% in 2015 to 25.4% in 2019. Digestive diseases and respiratory diseases were two main diseases, and accounted for 46.0% and 38.4%, respectively. This study provides an overview on dairy calves raising practices in China.

Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting Nlrp3 Expression

The aim of this study is to compare the regulatory abilities of citrus flavonoids on the oscillating expression of circadian genes. Seven varieties of citrus fruits and twenty-five citrus flavonoids were selected and evaluated. Per2 luciferase bioluminescence report system and serum shock were used to induce circadian gene expression in mouse microglia BV-2 cells. In vivo experiments were carried out using C57BL6/J mice to evaluate the regulation of flavonoids on the oscillatory expression of liver biorhythm genes. Lipopolysaccharide was used to interfere the gene oscillating expression. QRT-PCR was performed to detect the expression of circadian rhythm-related genes, including Clock, Bmal1, Per1, Per2, Per3, Cry1, Cry2, Rev-erbα, Rev-erbβ, Rorα, Dbp, and Npas2. The results show that the polymethoxyflavones (PMFs) exerted stronger circadian gene regulatory capability, while the flavonoids containing glycosides showed no biological activity. Also, all tested flavonoids decreased LPS-induced nitric oxide release, but only polymethoxyflavones inhibited circadian rhythm disorder. PMFs inhibited Nlrp3 inflammasome-related genes and proteins, including Nlrp3, IL-1β, ASC, and Caspase1, while other flavonoids only affected IL-1β and Caspase1 expression. This mechanism was preliminarily verified using the Nlrp3 inhibitor INF39.

MaRRS : a software system for generating multimedia radiology reports using Adobe Acrobat

Despite the proliferation of multimedia software technologies, radiology reports continue to lack image content that would improve the ability of referring clinicians to fully interpret and analyze radiological findings. This thesis demonstrates that it is possible to construct a radiology reporting software system that contains both text and image content using only "off-the-shelf" multimedia software. Specifically, a software system is presented that provides enhanced visual multimedia capabilities, structured content, and reduced report production time, using a well-known PDF program, Adobe Acrobat. The system, which we call the Multimedia Radiology Report System, or MaRRs, allows radiologists to quickly and simply create and deliver effective interactive multimedia medical reports. A detailed analysis describing the unique structure and functionality of MaRRS will be presented to demonstrate its advantages for both radiologists and referring clinicians.

MaRRS : a software system for generating multimedia radiology reports using Adobe Acrobat

Despite the proliferation of multimedia software technologies, radiology reports continue to lack image content that would improve the ability of referring clinicians to fully interpret and analyze radiological findings. This thesis demonstrates that it is possible to construct a radiology reporting software system that contains both text and image content using only "off-the-shelf" multimedia software. Specifically, a software system is presented that provides enhanced visual multimedia capabilities, structured content, and reduced report production time, using a well-known PDF program, Adobe Acrobat. The system, which we call the Multimedia Radiology Report System, or MaRRs, allows radiologists to quickly and simply create and deliver effective interactive multimedia medical reports. A detailed analysis describing the unique structure and functionality of MaRRS will be presented to demonstrate its advantages for both radiologists and referring clinicians.

Safety of SGLT2 Inhibitors: A Pharmacovigilance Study From 2015 to 2020 Based on FDA Adverse Event Report System Database

Aim: With the widespread use of SGLT2i, various adverse events (AEs) have been reported. This study aimed to describe the distribution of SGLT2i-related AEs in different systems, quantify the association of important medical events (IMEs) and SGLT2i regimens, and build a signal profile of SGLT2i- induced IMEs. Methods: Data from 2015 Q1 to 2020 Q4 in the FDA Adverse Event Reporting System database (FAERS) were selected to conduct disproportionality analysis. Two signal indicators, the reported odds ratio (ROR) and information component (IC), were used to evaluate the correlation between SGLT2i and IMEs. The lower end of the 95% confidence interval of IC (IC025) exceeding zero was deemed a signal. For ROR, it was defined a signal if ROR025 over one, with at least 3 cases. Results: A total of 45,771,436 records were involved, including 111,564 records related to SGLT2i, with 38,366 records of SGLT2i-induced IMEs. Overall, SGLT2i was significantly associated with IMEs (IC=0.36, 95% CI: 0.35-0.38; ROR=1.44, 95% CI: 1.42-1.46). Most SGLT2i-related adverse events occurred in monotherapy (92.93%). Diabetic ketoacidosis was the most IMEs. Specifically, acute osteomyelitis has the strongest signal of all SGLT2i (IC025=7.83), and it was unique to canagliflozin. Diabetic ketoacidosis, acute kidney injury, ketoacidosis, Fournier’s gangrene, and euglycemic diabetic ketoacidosis were common to the four FDA-approved SGLT2i. Conclusion: Our study demonstrated that different SGLT2i regimens lead to different important adverse events, but there are overlapping events. Early identification and management of SGLT2i-associated IMEs are essential for clinical practice.