scholarly journals Secondary hypogonadism following hand, foot, and mouth disease in an adult: a case report and review of literature

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Zhaoying Chen ◽  
Chen Jiang ◽  
Xiaoyu Cheng ◽  
Lidan Ma ◽  
Ying Xin ◽  
...  

Abstract Background Previous reports have described hypogonadism associated with virus infection such as hantavirus, human immunodeficiency virus (HIV) or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). However, to our best knowledge there has been no case report of secondary hypogonadism following hand, foot, and mouth disease (HFMD). Case presentation A previously healthy 28-year-old man with no history of major physical and psychological trauma, presented with bilateral gynecomastia and erectile dysfunction 2 weeks after HFMD. Laboratory testament showed the level of gonadotropin hormones declined. Imaging examination demonstrated no major abnormal change in pituitary or reproductive system. The diagnosis of hypogonadism was established. Then the patient was ordered to maintain mental health outward of hospital without drug intervention. One month after presentation, his gonadotropin hormone level and sexual desire had recovered, while bilateral gynecomastia and erectile dysfunction symptoms disappeared. Conclusions Physicians should notice the possibility for hypogonadism in adult patients with a recent history of HFMD.

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Ivanildo Pedro de Sousa ◽  
Heloísa Ihle Giamberardino ◽  
Sonia Mara Raboni ◽  
Maria Carmo Debur ◽  
Maria de Lourdes Aguiar Oliveira ◽  
...  

Abstract Background Although most enterovirus (EV) infections can be asymptomatic, these viral agents can cause serious conditions associated with central nervous system, respiratory disease and uncommon manifestations of hand, foot and mouth disease (HFMD). EV-coinfections have been rarely reported with development of complications and severe clinical outcome. An atypical case of a child presenting HFMD and severe acute respiratory syndrome, co-infected with EV-D68 and CVA6, is reported herein. Case presentation A 3-year-old boy was admitted in the emergency department unit showing fever, abdominal pain and tachycardia. Twenty-four hours after hospitalization the child developed severe clinical symptoms associated with HFMD and was discharged after recovery. Two days later, the child was readmitted with fever, cough and respiratory distress. RT-PCR and Sanger sequencing confirmed positivity for EV-D68 and CVA6 in oro and nasopharynges swabs and vesicles fluid, respectively. Phylogenetic analysis based on VP1 gene sequences suggested that CVA6 was closely related with HFMD viruses circulating in Turkey, while EV-D68 was genetically related to a Chinese strain. Conclusions To the best of our knowledge, this case is the first report of a double infection caused by CVA6 and EV-D68, which shed light on the pathogenesis of enterovirus infections. Further studies must be conducted to ascertain the role and clinical significance of EV co-infections, as well as a potential synergistic pathway between these viruses.


2016 ◽  
Vol 9 (1) ◽  
Author(s):  
Carlos Omaña-Cepeda ◽  
Andrea Martínez-Valverde ◽  
María del Mar Sabater- Recolons ◽  
Enric Jané-Salas ◽  
Antonio Marí-Roig ◽  
...  

Medwave ◽  
2019 ◽  
Vol 19 (07) ◽  
pp. e7683-e7683
Author(s):  
Janett Velástegui ◽  
Ligia Cova ◽  
Yomaira Galarza ◽  
Pablo Fierro ◽  
Lenier León Baryolo ◽  
...  

2013 ◽  
Vol 2 (1) ◽  
pp. 75
Author(s):  
Shruthi Hegde ◽  
Reema Rao ◽  
Reshma Suvarna ◽  
Subhas Babu

2020 ◽  
pp. 112067212098252
Author(s):  
Pietro Maria Talli ◽  
Edlira Bendo ◽  
Emilio Pedrotti ◽  
Alberto Pazzaglia

Purpose: To report the case of a 33-year old man who disclosed the first case of bilateral ocular involvement of hand, foot, and mouth disease (HFMD) with a different stage of the disease in each eye. Methods: Retrospective case report. Results: The study included a patient who incurred in a bilateral HFMD maculopathy. During 6 months follow-up period persistent abnormalities in fundus examination and in OCT scans were reported. Conclusion: We consider that our case shows that choriocapillaris is the primary target of HFMD maculopathy, for this reason we consider that ICGA is mandatory for early diagnosis and an effective treatment.


2020 ◽  
Vol 55 (4) ◽  
pp. 764-792
Author(s):  
Thomas Rath

This article explores how the Mexican state gathered, archived and destroyed information. It focuses on the US–Mexico campaign against foot-and-mouth disease between 1947 and 1952, whose paper archive Mexican officials burned near the successful conclusion of the campaign. This article argues that several factors shaped the context for this documentary bonfire and made the 1940s a key point of inflection in Mexico’s history of official information-gathering: the dominant party’s system of elite power-sharing, the growth of a reading public and the regime’s drift rightward. At the same time, the nature of the foot-and-mouth disease campaign itself ensured that, despite its possible uses, the archive was particularly sensitive, providing evidence of the embarrassing gaps that began to yawn between the state’s language of revolutionary nationalism and its political practise. Indeed, the bonfire represented the culmination of practises Mexican officials had already developed throughout the campaign to reconcile the demands of legibility and deniability, hemispheric integration and nationalism, political stability and state capacity. More broadly, the case illustrates the uneven effects of US assistance on the development of state capacity, the authoritarian but institutionally weak character of the early PRIísta state, and the role of archives in maintaining a coherent image of state sovereignty.


PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49650 ◽  
Author(s):  
Begoña Valdazo-González ◽  
Lilyana Polihronova ◽  
Tsviatko Alexandrov ◽  
Preben Normann ◽  
Nick J. Knowles ◽  
...  

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