scholarly journals Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome – results from the Norwegian Mother and Child Cohort Study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Dominika Modzelewska ◽  
Rino Bellocco ◽  
Anders Elfvin ◽  
Anne Lise Brantsæter ◽  
Helle Margrete Meltzer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Neonatal Outcome ◽  
Mother And Child ◽  
Exposure During Pregnancy ◽  
Caffeine Exposure

scholarly journals Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study

2013 ◽  
Vol 17 (9) ◽  
pp. 2071-2080 ◽  
Author(s):  
Kristine Vejrup ◽  
Anne Lise Brantsæter ◽  
Helle K Knutsen ◽  
Per Magnus ◽  
Jan Alexander ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Dietary Exposure ◽  
Increased Risk ◽  
Mother And Child ◽  
Multivariable Regression Models ◽  
Infant Birth ◽  
In Pregnancy

AbstractObjectiveTo examine the association between calculated maternal dietary exposure to Hg in pregnancy and infant birth weight in the Norwegian Mother and Child Cohort Study (MoBa).DesignExposure was calculated with use of a constructed database of Hg in food items and reported dietary intake during pregnancy. Multivariable regression models were used to explore the association between maternal Hg exposure and infant birth weight, and to model associations with small-for-gestational-age offspring.SettingThe study is based on data from MoBa.SubjectsThe study sample consisted of 62 941 women who answered a validated FFQ which covered the habitual diet during the first five months of pregnancy.ResultsMedian exposure to Hg was 0·15 μg/kg body weight per week and the contribution from seafood intake was 88 % of total Hg exposure. Women in the highest quintile compared with the lowest quintile of Hg exposure delivered offspring with 34 g lower birth weight (95 % CI −46 g, −22 g) and had an increased risk of giving birth to small-for-gestational-age offspring, adjusted OR = 1·19 (95 % CI 1·08, 1·30). Although seafood intake was positively associated with increased birth weight, stratified analyses showed negative associations between Hg exposure and birth weight within strata of seafood intake.ConclusionsAlthough seafood intake in pregnancy is positively associated with birth weight, Hg exposure is negatively associated with birth weight. Seafood consumption during pregnancy should not be avoided, but clarification is needed to identify at what level of Hg exposure this risk might exceed the benefits of seafood.

Early-Onset Thrombocytopenia in Small-for-Gestational-Age Neonates: A Retrospective Cohort Study

2016 ◽  
Vol 33 (S 01) ◽  
Author(s):  
S. Fustolo-Gunnink ◽  
R. Vlug ◽  
V. Smits-Wintjens ◽  
E. Heckman ◽  
A. Te Pas ◽  
...  
Keyword(s):  
Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Retrospective Cohort Study ◽  
Early Onset ◽  
Retrospective Cohort

126. Sex and growth specific characteristics of small for gestational age neonates: A prospective cohort study

2018 ◽  
Vol 13 ◽  
pp. S24-S25
Author(s):  
Eva van der Vlugt ◽  
Petra Verburg ◽  
Shalem Leemaqz ◽  
Lesley Mccowan ◽  
Lucilla Poston ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Prospective Cohort

scholarly journals Reduced prevalence of small-for-gestational-age and preterm birth for women of low socioeconomic position: a population-based cohort study comparing antenatal midwifery and physician models of care

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e022220 ◽  
Author(s):  
Daphne N McRae ◽  
Patricia A Janssen ◽  
Saraswathi Vedam ◽  
Maureen Mayhew ◽  
Deborah Mpofu ◽  
...  
Keyword(s):  
British Columbia ◽  
Cohort Study ◽  
Preterm Birth ◽  
Gestational Age ◽  
Socioeconomic Position ◽  
Small For Gestational Age ◽  
Models Of Care ◽  
Midwifery Care ◽  
Low Socioeconomic ◽  
Lower Odds

ObjectiveOur aim was to investigate if antenatal midwifery care was associated with lower odds of small-for-gestational-age (SGA) birth, preterm birth (PTB) or low birth weight (LBW) compared with general practitioner (GP) or obstetrician (OB) models of care for women of low socioeconomic position.SettingThis population-level, retrospective cohort study used province-wide maternity, medical billing and demographic data from British Columbia, Canada.ParticipantsOur study included 57 872 pregnant women, with low socioeconomic position, who: were residents of British Columbia, Canada, carried a singleton fetus, had low to moderate medical/obstetric risk, delivered between 2005 and 2012 and received medical insurance premium assistance.Primary and secondary outcome measuresWe report rates, adjusted ORs (aOR), and 95% CIs for the primary outcome, SGA birth (<the 10th percentile), and secondary outcomes, PTB (<37 weeks’ completed gestation) and LBW (<2500 g).ResultsOur sample included 4705 midwifery patients, 45 114 GP patients and 8053 OB patients. Odds of SGA birth were reduced for patients receiving antenatal midwifery versus GP (aOR 0.71, 95% CI 0.62 to 0.82) or OB care (aOR 0.59, 95% CI 0.50 to 0.69). Odds of PTB were lower for antenatal midwifery versus GP (aOR 0.74, 95% CI 0.63 to 0.86) or OB patients (aOR 0.53, 95% CI 0.45 to 0.62). Odds of LBW were reduced for midwifery versus GP (aOR 0.66, 95% CI 0.53 to 0.82) or OB patients (aOR 0.43, 95% CI 0.34 to 0.54).ConclusionAntenatal midwifery care in British Columbia, Canada, was associated with lower odds of SGA birth, PTB and LBW, for women of low socioeconomic position, compared with physician models of care. Results support the development of policy to ensure antenatal midwifery care is available and accessible for women of low socioeconomic position. Future research is needed to determine the underlying mechanisms linking midwifery care to better birth outcomes for women of low socioeconomic position.

scholarly journals Early-Onset Thrombocytopenia in Small-For-Gestational-Age Neonates: A Retrospective Cohort Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0154853 ◽  
Author(s):  
S. F. Fustolo-Gunnink ◽  
R. D. Vlug ◽  
V. E. H. J. Smits-Wintjens ◽  
E. J. Heckman ◽  
A. B. te Pas ◽  
...  
Keyword(s):  
Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Retrospective Cohort Study ◽  
Early Onset ◽  
Retrospective Cohort

scholarly journals Longitudinal changes of cardiotocographic parameters throughout pregnancy: a prospective cohort study comparing small-for-gestational-age and normal fetuses from 24 to 40 weeks

2017 ◽  
Vol 45 (4) ◽  
Author(s):  
Célia Amorim-Costa ◽  
A. Rita Gaio ◽  
Diogo Ayres-de-Campos ◽  
João Bernardes
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Prospective Cohort ◽  
Parallel Increase ◽  
Fetal Malformations ◽  
First Time

AbstractObjective:To compare longitudinal trends of cardiotocographic (CTG) parameters between small-for-gestational-age (SGA) and normal fetuses, from 24 to 41 weeks of pregnancy.Methods:A prospective cohort study was carried out in singleton pregnancies without fetal malformations. At least one CTG was performed in each of the following intervals: 24–26 weeks+6 days, 27–29 weeks+6 days, 30–32 weeks+6 days, 33–35 weeks+6 days, 36–38 weeks+6 days and ≥39 weeks. Tracings were analyzed using the Omniview-SisPortoResults:A total of 176 fetuses (31 SGA) and 1256 tracings (207 from SGA fetuses) were evaluated. All CTG parameters changed significantly throughout pregnancy in the three groups, with a decreasing baseline and probability of decelerations, and an increasing average long-term variability (LTV), average short-term variability (STV) and accelerations. Baseline showed a more pronounced decrease (steeper slope) in SGA fetuses, being higher in these cases at earlier gestational ages and lower later in pregnancy. Average LTV was significantly lower in SGA<p3 fetuses, but a parallel increase occurred in all groups. There was a considerable inter-fetal variability within each group.Conclusion:A unique characterization of CTG trends throughout gestation in SGA fetuses was provided. A steeper descent of the baseline was reported for the first time. The findings raise the possibility of clinical application of computerized CTG analysis in screening and management of fetal growth restriction.

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