High starchy food intake may increase the risk of adverse pregnancy outcomes: a nested case-control study in the Shaanxi province of Northwestern China

Abstract Background There was a wider disparity in the diet characterization among most studies on diet and pregnancy outcomes in different countries, and the research in northern China is limited. Therefore, the purpose of the present study that was conducted in northwest China was to understand the dietary characteristics of periconceptional women and to explore the relationship between and specific dietary patterns with adverse pregnancy outcomes. Methods A nested case-control study was conducted from October 2017 to November 2018 in Shaanxi, China. Based on a prospective cohort of 368 women who were pregnant or prepared for pregnancy, 63 participants who developed the outcomes of gestational hypertension, gestational diabetes, preterm birth, low birth weight, and birth defects were included in the case group. A total of 237 healthy pregnant women were included during the same period in the control group. Dietary intake was assessed using a validated food frequency questionnaire for the three months before pregnancy and the first trimester. Information on delivery details and antenatal pregnancy complications was obtained from the hospital maternity records. Dietary patterns were derived using factor analysis. Stratified analysis was performed on the overall, single and multiple adverse pregnancy outcomes categories. Adjustment was made for sociodemographic characteristics and nutritional supplement status. Results Six major dietary patterns were identified. The ‘starchy’ dietary pattern, composed of high intake in noodle and flour products and/or rice and its products, was associated with the odds of developing of adverse pregnancy outcomes (OR: 2.324, 95% CI: 1.293–4.178). This risk remained significant following adjustment for potential confounders of maternal demographic characteristics and nutritional status (aOR: 2.337, 95% CI:1.253–4.331). Strong association were found during the first trimester of pregnancy, but showed no association during the three months before pregnancy (aOR:1.473, 95% CI: 0.682–3.234). Conclusions High starchy food intake was associated with adverse pregnancy outcomes, particularly during the first trimester of pregnancy. Health education focusing on periconceptional dietary patterns could be a practical strategy for preventing adverse pregnancy outcomes.

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Determinants of Adverse Pregnancy Outcomes among mothers who gave birth from Jan 1-Dec 31/2015 in Jimma University Specialized Hospital, Case control study, 2016

Medical & Clinical Reviews ◽

10.21767/2471-299x.1000063 ◽

2017 ◽

Vol 03 (04) ◽

Cited By ~ 1

Author(s):

Eyosiyas Yeshialem ◽

Nigus Alemnew ◽

Mulumebet Abera ◽

Amanuel Tesfay

Keyword(s):

Pregnancy Outcomes ◽

Case Control Study ◽

Case Control ◽

Adverse Pregnancy Outcomes ◽

Hospital Case ◽

Specialized Hospital ◽

Adverse Pregnancy ◽

Jimma University ◽

Control Study

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Serum placental growth factor in late first trimester of pregnancy for prediction of preeclampsia in primigravida - a case control study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20164641 ◽

2016 ◽

Vol 6 (1) ◽

pp. 106

Author(s):

Rachna Agarwal ◽

Shweta Chaudhary ◽

Rajarshi Kar ◽

Gita Radhakrishnan ◽

Richa Sharma

Keyword(s):

Case Control Study ◽

Gestational Hypertension ◽

Final Analysis ◽

First Trimester ◽

Case Control ◽

Placental Growth Factor ◽

Serum Samples ◽

First Trimester Of Pregnancy ◽

Nested Case Control ◽

Control Study

Background: We studied the correlation of serum PLGF levels at 11-14 weeks in primigravida for prediction of future preeclampsia in a prospective nested case control study and estimated the critical levels of PLGF for possible use as screening test.Methods: Subjects with preeclampsia/gestational hypertension were taken as cases with an equal number of controls.Results: Out of 300 participants, final analysis was possible in 291 subjects. Thirty five were cases; two had early PE, 15 late PE and 18 had GH. PLGF level was lower in cases (20 pg/ml) compared to controls (79 pg/ml). PLGF was significantly lower in PE cases (15 pg/ml) compared to GH cases (34 pg/ml). PLGF had maximum area under the ROC curve (AUC) for PE with value of 0.867. Further, late PE had more AUC (0.853) as compared to GH (0.759). The cut off value for prediction of PE was found to be <30 pg/ml with 88.2% sensitivity and 71.4% specificity.Conclusions: PLGF levels were significantly lower in first trimester serum samples of subjects who later developed either preeclampsia or gestational hypertension. PLGF had better detection rate for PE and late PE as compared to GH.

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P125 Inherited thrombophilias and adverse pregnancy outcomes: a case-control study in an Australian population

Pregnancy Hypertension ◽

10.1016/s2210-7789(10)60291-7 ◽

2010 ◽

Vol 1 ◽

pp. S75

Author(s):

Joanne Said ◽

John Higgins ◽

Eric Moses ◽

Susan Walker ◽

Paul Monagle ◽

...

Keyword(s):

Pregnancy Outcomes ◽

Case Control Study ◽

Case Control ◽

Adverse Pregnancy Outcomes ◽

Australian Population ◽

Adverse Pregnancy ◽

Control Study

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Angiopoietin 1 and 2 serum concentrations in first trimester of pregnancy as biomarkers of adverse pregnancy outcomes

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2013.11.012 ◽

2014 ◽

Vol 210 (4) ◽

pp. 345.e1-345.e9 ◽

Cited By ~ 13

Author(s):

Francisco J. Schneuer ◽

Christine L. Roberts ◽

Anthony W. Ashton ◽

Cyrille Guilbert ◽

Vitomir Tasevski ◽

...

Keyword(s):

Pregnancy Outcomes ◽

First Trimester ◽

Adverse Pregnancy Outcomes ◽

Serum Concentrations ◽

First Trimester Of Pregnancy ◽

Adverse Pregnancy ◽

Angiopoietin 1

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A comparative study of pregnancy outcomes among women with and without threatened miscarriage in the first trimester in Abakaliki Southeast Nigeria

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193789 ◽

2019 ◽

Vol 8 (9) ◽

pp. 3639

Author(s):

Johnbosco Ifunanya Nwafor ◽

Victor Jude Uchenna Onuchukwu ◽

Vitus Okwuchukwu Obi ◽

Darlinghton-Peter Chibuzor Ugoji ◽

Blessing Idzuinya Onwe ◽

...

Keyword(s):

Pregnancy Outcomes ◽

Neonatal Intensive Care ◽

First Trimester ◽

Adverse Pregnancy Outcomes ◽

University Teaching ◽

Retrospective Case ◽

Threatened Miscarriage ◽

Increased Risk ◽

Adverse Pregnancy ◽

Control Study

Background:Threatened miscarriage is the commonest complication of pregnancy and has been aBackground: Threatened miscarriage is the commonest complication of pregnancy and has been associated with adverse pregnancy outcomes. Therefore, the aim of this study is to determine the association between threatened miscarriage and adverse maternal and perinatal outcomes.Methods: This was a retrospective case-control study undertaken at the Alex Ekwueme Federal University Teaching Hospital, Abakaliki. The study involved 228 women presenting with threatened miscarriage in the first trimester and 228 asymptomatic matched controls. The statistical analysis was done using Epi info version 7.1.5, March 2015 (CDC, Atlanta, Georgia, USA).Results: Women with threatened miscarriage were more likely to have preterm delivery (OR = 7.1, 95% CI = 3.51-14.32, P <0.0001), placenta praevia (OR = 2.4, 95% CI = 1.13 - 5.26, P = 0.03), placental abruption (OR = 3.6, 95% CI = 1.40 - 9.03, P = 0.01) and retained placenta (OR = 2.9, 95% CI = 1.18 - 6.97, P = 0.02). Similarly, women with first trimester threatened miscarriage were more likely to develop postpartum haemorrhage (OR = 2.4, 95% CI = 1.17 - 5.06, P = 0.02). There was no significant differences in the stillbirth rate, Apgar scores at 5 minutes less than 7, admission into neonatal intensive care unit and early neonatal death. Threatened miscarriage was associated with intrauterine growth restriction (OR = 3.5, 95% CI = 1.77 - 6.88, P <0.0001) and low birth weight <2.kg (OR = 3.2, 95% CI = 1.33 - 7.69, P = 0.01).Conclusions: Women with threatened miscarriage in the first trimester are at increased risk of adverse pregnancy outcomes and the risk factors should be taken into consideration when deciding upon antenatal surveillance and management of their pregnancies.

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