Perinatal outcomes of frequent attendance in midwifery care in the Netherlands: a retrospective cohort study

Abstract Background Racial disparities in adverse perinatal outcomes have been studied in other countries, but little has been done for the Canadian population. In this study, we sought to examine the disparities in adverse perinatal outcomes between Asians and Caucasians in Ontario, Canada. Methods We conducted a population-based retrospective cohort study that included all Asian and Caucasian women who attended a prenatal screening and resulted in a singleton birth in an Ontario hospital (April 1st, 2015-March 31st, 2017). Generalized estimating equation models were used to estimate the independent adjusted relative risks and adjusted risk difference of adverse perinatal outcomes for Asians compared with Caucasians. Results Among 237,293 eligible women, 31% were Asian and 69% were Caucasian. Asians were at an increased risk of gestational diabetes mellitus, placental previa, early preterm birth (< 32 weeks), preterm birth, emergency cesarean section, 3rd and 4th degree perineal tears, low birth weight (< 2500 g, < 1500 g), small-for-gestational-age (<10th percentile, <3rd percentile), neonatal intensive care unit admission, and hyperbilirubinemia requiring treatment, but had lower risks of preeclampsia, macrosomia (birth weight > 4000 g), large-for-gestational-age neonates, 5-min Apgar score < 7, and arterial cord pH ≤7.1, as compared with Caucasians. No difference in risk of elective cesarean section was observed between Asians and Caucasians. Conclusion There are significant differences in several adverse perinatal outcomes between Asians and Caucasians. These differences should be taken into consideration for clinical practices due to the large Asian population in Canada.

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Community-acquired bacteraemia in COVID-19 in comparison to influenza A and influenza B: a retrospective cohort study

BMC Infectious Diseases ◽

10.1186/s12879-021-05902-5 ◽

2021 ◽

Vol 21 (1) ◽

Cited By ~ 1

Author(s):

Julinha M. Thelen ◽

A. G. ( Noud) Buenen ◽

Marjan van Apeldoorn ◽

Heiman F. Wertheim ◽

Mirjam H. A. Hermans ◽

...

Keyword(s):

Cohort Study ◽

Blood Culture ◽

The Netherlands ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Influenza A ◽

Blood Cultures ◽

Influenza B ◽

Significant Difference ◽

All Cause Mortality

Abstract Background During the coronavirus disease 2019 (COVID-19) pandemic in the Netherlands it was noticed that very few blood cultures from COVID-19 patients turned positive with clinically relevant bacteria. This was particularly evident in comparison to the number of positive blood cultures during previous seasonal epidemics of influenza. This observation raised questions about the occurrence and causative microorganisms of bacteraemia in COVID-19 patients, especially in the perspective of the widely reported overuse of antibiotics and the rising rate of antibiotic resistance. Methods We conducted a retrospective cohort study on blood culture results in influenza A, influenza B and COVID-19 patients presenting to two hospitals in the Netherlands. Our main outcome consisted of the percentage of positive blood cultures. The percentage of clinically relevant blood cultures, isolated bacteria and 30-day all-cause mortality served as our secondary outcomes. Results A total of 1331 viral episodes were analysed in 1324 patients. There was no statistically significant difference (p = 0.47) in overall occurrence of blood culture positivity in COVID-19 patients (9.0, 95% CI 6.8–11.1) in comparison to influenza A (11.4, 95% CI 7.9–14.8) and influenza B patients (10.4, 95% CI 7.1–13.7,). After correcting for the high rate of contamination, the occurrence of clinically relevant bacteraemia in COVID-19 patients amounted to 1.0% (95% CI 0.3–1.8), which was statistically significantly lower (p = 0.04) compared to influenza A patients (4.0, 95% CI 1.9–6.1) and influenza B patients (3.0, 95% CI 1.2–4.9). The most frequently identified bacterial isolates in COVID-19 patients were Escherichia coli (n = 2) and Streptococcus pneumoniae (n = 2). The overall 30-day all-cause mortality for COVID-19 patients was 28.3% (95% CI 24.9–31.7), which was statistically significantly higher (p = <.001) when compared to patients with influenza A (7.1, 95% CI 4.3–9.9) and patients with influenza B (6.4, 95% CI 3.8–9.1). Conclusions We report a very low occurrence of community-acquired bacteraemia amongst COVID-19 patients in comparison to influenza patients. These results reinforce current clinical guidelines on antibiotic management in COVID-19, which only advise utilization of antibiotics when a bacterial co-infection is suspected.

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Persistence after treatment of pharyngeal gonococcal infections in patients of the STI clinic, Amsterdam, the Netherlands, 2012–2015: a retrospective cohort study

Sexually Transmitted Infections ◽

10.1136/sextrans-2017-053147 ◽

2017 ◽

Vol 93 (7) ◽

pp. 467-471 ◽

Cited By ~ 11

Author(s):

I Putu Yuda Hananta ◽

Henry John Christiaan De Vries ◽

Alje P van Dam ◽

Martijn Sebastiaan van Rooijen ◽

Hardyanto Soebono ◽

...

Keyword(s):

Cohort Study ◽

The Netherlands ◽

Retrospective Cohort Study ◽

Retrospective Cohort

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Re: Perinatal outcomes after open fetal surgery for myelomeningocele repair: a retrospective cohort study

BJOG An International Journal of Obstetrics & Gynaecology ◽

10.1111/1471-0528.15464 ◽

2018 ◽

Vol 126 (1) ◽

pp. 131-132 ◽

Cited By ~ 1

Author(s):

Antonio Fernandes Moron ◽

Mauricio Mendes Barbosa ◽

Herbene José Figuinha Milani ◽

Stephanno Gomes Sarmento ◽

Eduardo Felix Martins Santana ◽

...

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Fetal Surgery ◽

Perinatal Outcomes ◽

Myelomeningocele Repair

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Perinatal outcomes after open fetal surgery for myelomeningocele repair: a retrospective cohort study

BJOG An International Journal of Obstetrics & Gynaecology ◽

10.1111/1471-0528.15312 ◽

2018 ◽

Vol 125 (10) ◽

pp. 1280-1286 ◽

Cited By ~ 20

Author(s):

AF Moron ◽

MM Barbosa ◽

HJF Milani ◽

SG Sarmento ◽

EFM Santana ◽

...

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Fetal Surgery ◽

Perinatal Outcomes ◽

Myelomeningocele Repair

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Perinatal Outcomes of Monochorionic-Diamniotic Twin Pregnancies Uncomplicated at 28 Weeks of Gestation

Japanese Clinical Medicine ◽

10.4137/jcm.s38895 ◽

2016 ◽

Vol 7 ◽

pp. JCM.S38895 ◽

Cited By ~ 3

Author(s):

Shunji Suzuki

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Perinatal Outcomes ◽

Second Trimester ◽

Perinatal Complications ◽

Third Trimester ◽

The Third ◽

Perinatal Center ◽

Twin Pregnancies

We examined the prevalence of specific perinatal complications of monochorionic-diamniotic twin pregnancies in cases without any abnormal findings until the second trimester of pregnancy. This was a retrospective cohort study performed at a tertiary perinatal center in Tokyo, Japan. There were 88 cases of uncomplicated monochorionic-diamniotic twin pregnancies at 28 weeks of gestation. In five of them (5.7%), there were serious complications associated with placental circulatory imbalance between the twins during the third trimester of pregnancy. Two cases were complicated by twin–twin transfusion syndrome, two cases were complicated by twin anemia–polycythemia sequence, and one case was complicated by acute twin–twin transfusion syndrome. In the five cases, no abnormal ultrasonographic findings or symptoms were recognized one or two weeks prior to the diagnosis. Fifty-eight cases (65.9%) were delivered at term uneventfully. Serious complications due to placental circulatory imbalance between twins occurred in about 6% of cases during the third trimester of pregnancy.

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