Diet and endometrial cancer: a focus on the role of fruit and vegetable intake, Mediterranean diet and dietary inflammatory index in the endometrial cancer risk

AbstractThe relation between inflammation deriving from diet and endometrial cancer risk has not yet been investigated. In this study, we explored the association between the dietary inflammatory index (DII) and endometrial cancer risk in an Italian case–control study. Cases comprised 454 patients with incident, histologically confirmed carcinoma of the endometrium, and controls comprised 908 subjects admitted to the same network of hospitals as cases for a wide spectrum of acute, non-neoplastic conditions. DII scores were computed on the basis of dietary intake assessed using a reproducible and valid seventy-eight-item FFQ. OR were calculated through logistic regression models conditioned on age and study centre and adjusted for recognised confounding factors, including total energy intake. Women with the most pro-inflammatory diet had a higher risk for endometrial cancer compared with women with the most anti-inflammatory diet (ORQuartile 4 v. 1 1·46; 95 % CI 1·02, 2·11; Ptrend=0·04). A pro-inflammatory diet may increase the risk for endometrial cancer.

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Insights about urinary hippuric and citric acid as biomarkers of fruit and vegetable intake in patients with kidney stones: The role of age and sex

Nutrition ◽

10.1016/j.nut.2018.07.112 ◽

2019 ◽

Vol 59 ◽

pp. 83-89 ◽

Cited By ~ 2

Author(s):

Angela Guerra ◽

Andrea Ticinesi ◽

Franca Allegri ◽

Antonio Nouvenne ◽

Beatrice Prati ◽

...

Keyword(s):

Citric Acid ◽

Kidney Stones ◽

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable ◽

Age And Sex

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Allium vegetables intake and endometrial cancer risk

Public Health Nutrition ◽

10.1017/s1368980008003820 ◽

2009 ◽

Vol 12 (9) ◽

pp. 1576-1579 ◽

Cited By ~ 25

Author(s):

Carlotta Galeone ◽

Claudio Pelucchi ◽

Luigino Dal Maso ◽

Eva Negri ◽

Maurizio Montella ◽

...

Keyword(s):

Endometrial Cancer ◽

Cancer Risk ◽

Case Control Study ◽

Wide Spectrum ◽

Protective Role ◽

Case Control ◽

Endometrial Cancer Risk ◽

Allium Vegetables ◽

Control Study

AbstractObjectiveThe potential role of allium vegetables on endometrial cancer risk has been scarcely investigated and the results of previous Chinese studies are not easily applicable to Western populations. Therefore, we evaluated the relationship between onion and garlic intake and endometrial cancer, using data from an Italian case–control study.SettingWe analysed data from a multi-centre case–control study of 454 endometrial cancer cases and 908 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions. Information was collected by trained interviewers using a validated and reproducible FFQ. Multivariate odds ratios and 95 % confidence intervals were obtained after allowance for recognized confounding factors.ResultsCompared with non-users, the OR of endometrial cancer for successive categories of onion intake were 0·94 (95 % CI 0·72, 1·21) for <2 portions/week and 0·40 (95 % CI 0·22, 0·72) for ≥2 portions/week, with a significant inverse trend in risk (P = 0·01). The OR for an increment of one portion (i.e. 80 g) of onions per week was 0·81 (95 % CI 0·70, 0·95). For garlic, the OR for successive categories of intake were 0·89 (95 % CI 0·68, 1·15) for intermediate use and 0·62 (95 % CI 0·42, 0·92) for high use, with a significant inverse trend in risk (P = 0·02).ConclusionsOur study found a moderate protective role of allium vegetables on the risk of endometrial cancer.

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Fruit and Vegetable Intake is Inversely Associated with Cancer Risk in Mexican-Americans

Nutrition and Cancer ◽

10.1080/01635581.2019.1603315 ◽

2019 ◽

Vol 71 (8) ◽

pp. 1254-1262 ◽

Cited By ~ 1

Author(s):

Shenghui Wu ◽

Susan P. Fisher-Hoch ◽

Belinda M. Reininger ◽

Miryoung Lee ◽

Joseph B. McCormick

Keyword(s):

Cancer Risk ◽

Mexican Americans ◽

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable

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Role of Organizational Support on Implementation of an Environmental Change Intervention to Improve Child Fruit and Vegetable Intake: a Randomized Cross-Over Design

Prevention Science ◽

10.1007/s11121-019-01043-z ◽

2019 ◽

Vol 20 (8) ◽

pp. 1211-1218 ◽

Cited By ~ 1

Author(s):

Jennifer L. Gay ◽

Ruth P. Saunders ◽

Erika Rees-Punia ◽

Marsha Dowda ◽

Alexandra E. van den Berg

Keyword(s):

Environmental Change ◽

Organizational Support ◽

Vegetable Intake ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable

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A case–control study in Shanghai of fruit and vegetable intake and endometrial cancer

British Journal of Cancer ◽

10.1038/sj.bjc.6602609 ◽

2005 ◽

Vol 92 (11) ◽

pp. 2059-2064 ◽

Cited By ~ 21

Author(s):

M H Tao ◽

W H Xu ◽

W Zheng ◽

Y T Gao ◽

Z X Ruan ◽

...

Keyword(s):

Endometrial Cancer ◽

Case Control Study ◽

Vegetable Intake ◽

Case Control ◽

Fruit And Vegetable Intake ◽

Fruit And Vegetable ◽

Control Study

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Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies

Molecular Psychiatry ◽

10.1038/s41380-018-0237-8 ◽

2018 ◽

Vol 24 (7) ◽

pp. 965-986 ◽

Cited By ~ 90

Author(s):

Camille Lassale ◽

G. David Batty ◽

Amaria Baghdadli ◽

Felice Jacka ◽

Almudena Sánchez-Villegas ◽

...

Keyword(s):

Systematic Review ◽

Relative Risk ◽

Longitudinal Studies ◽

Mediterranean Diet ◽

Meta Analysis ◽

Healthy Diet ◽

Dietary Inflammatory Index ◽

Cross Sectional ◽

Inflammatory Index

AbstractWith depression being the psychiatric disorder incurring the largest societal costs in developed countries, there is a need to gather evidence on the role of nutrition in depression, to help develop recommendations and guide future psychiatric health care. The aim of this systematic review was to synthesize the link between diet quality, measured using a range of predefined indices, and depressive outcomes. Medline, Embase and PsychInfo were searched up to 31st May 2018 for studies that examined adherence to a healthy diet in relation to depressive symptoms or clinical depression. Where possible, estimates were pooled using random effect meta-analysis with stratification by observational study design and dietary score. A total of 20 longitudinal and 21 cross-sectional studies were included. These studies utilized an array of dietary measures, including: different measures of adherence to the Mediterranean diet, the Healthy Eating Index (HEI) and Alternative HEI (AHEI), the Dietary Approaches to Stop Hypertension, and the Dietary Inflammatory Index. The most compelling evidence was found for the Mediterranean diet and incident depression, with a combined relative risk estimate of highest vs. lowest adherence category from four longitudinal studies of 0.67 (95% CI 0.55–0.82). A lower Dietary Inflammatory Index was also associated with lower depression incidence in four longitudinal studies (relative risk 0.76; 95% CI: 0.63–0.92). There were fewer longitudinal studies using other indices, but they and cross-sectional evidence also suggest an inverse association between healthy diet and depression (e.g., relative risk 0.65; 95% CI 0.50–0.84 for HEI/AHEI). To conclude, adhering to a healthy diet, in particular a traditional Mediterranean diet, or avoiding a pro-inflammatory diet appears to confer some protection against depression in observational studies. This provides a reasonable evidence base to assess the role of dietary interventions to prevent depression. This systematic review was registered in the PROSPERO International Prospective Register of Systematic Reviews under the number CRD42017080579.

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