Mutational spectrum of acquired resistance to reversible versus irreversible EGFR tyrosine kinase inhibitors

10.1186/s12885-020-06920-3 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Svenja Wagener-Ryczek ◽

Carina Heydt ◽

Juliane Süptitz ◽

Sebastian Michels ◽

Markus Falk ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Mutational Spectrum ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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Mutational spectrum of acquired resistance to reversible versus irreversible EGFR tyrosine kinase inhibitors

Annals of Oncology ◽

10.1093/annonc/mdz063.032 ◽

2019 ◽

Vol 30 ◽

pp. ii51 ◽

Author(s):

S. Wagener-Ryczek ◽

C. Heydt ◽

J. Sueptitz ◽

S. Michels ◽

M. Falk ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Mutational Spectrum ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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P76.85 Afatinib and Necitumumab in EGFR mutant NSCLC with Acquired Resistance to 1st or 3rd Generation EGFR Tyrosine Kinase Inhibitors

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2021.01.1142 ◽

2021 ◽

Vol 16 (3) ◽

pp. S626

Author(s):

S. Padda ◽

J. Whisenant ◽

J. Neal ◽

S. York ◽

W. Iams ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

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Abstract 742: Effect of Hsp90 inhibitor NVP-AUY922 with radiation on lung adenocarcinoma cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors

10.1158/1538-7445.am2015-742 ◽

2015 ◽

Author(s):

Yuho Maki ◽

Shinsuke Hashida ◽

Hiromasa Yamamoto ◽

Kazuhiko Shien ◽

Tomoaki Ohtsuka ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Hsp90 Inhibitor ◽

Adenocarcinoma Cell ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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An activation of LC3A-mediated autophagy contributes tode novoand acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma

The Journal of Pathology ◽

10.1002/path.4354 ◽

2014 ◽

pp. n/a-n/a ◽

Author(s):

Kaito Nihira ◽

Yasuhiro Miki ◽

Shinya Iida ◽

Sodai Narumi ◽

Katsuhiko Ono ◽

...

Keyword(s):

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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Acquired Resistance to EGFR Tyrosine Kinase Inhibitors is Associated With Low Efficacy of Radiation Therapy for Brain Metastases From EGFR-mutant Lung Adenocarcinoma

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2012.07.166 ◽

2012 ◽

Vol 84 (3) ◽

pp. S102

Author(s):

H. Hirata ◽

K. Nakamura ◽

N. Kunitake ◽

Y. Shioyama ◽

T. Sasaki ◽

...

Keyword(s):

Radiation Therapy ◽

Brain Metastases ◽

Tyrosine Kinase ◽

Lung Adenocarcinoma ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

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Abstract 77: Therapeutic potential of ERK inhibitors in overcoming acquired resistance to third generation EGFR tyrosine kinase inhibitors

10.1158/1538-7445.am2019-77 ◽

2019 ◽

Author(s):

Yiting Li ◽

Guoqing Qian ◽

Taofeek K. Owonikoko ◽

Suresh S. Ramalingam ◽

Shi-Yong Sun

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Therapeutic Potential ◽

Acquired Resistance ◽

Third Generation ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors

Annals of Oncology ◽

10.1093/annonc/mdx703 ◽

2018 ◽

Vol 29 ◽

pp. i10-i19 ◽

Author(s):

D. Westover ◽

J. Zugazagoitia ◽

B.C. Cho ◽

C.M. Lovly ◽

L. Paz-Ares

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Second Generation ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

First And Second Generation

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Clinical course of patients (pts) with acquired resistance (AR) to EGFR tyrosine kinase inhibitors (TKI).

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.7520 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 7520-7520 ◽

Author(s):

G. R. Oxnard ◽

G. J. Riely ◽

M. H. Arcila ◽

M. G. Kris ◽

W. Pao ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Clinical Course ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors

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BRAF Fusion — Another Mechanism of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.03.003 ◽

2019 ◽

Vol 14 (5) ◽

pp. 764-765 ◽

Author(s):

Tetsuya Mitsudomi

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

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Loss of Activating EGFR Mutant Gene Contributes to Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0041017 ◽

2012 ◽

Vol 7 (7) ◽

pp. e41017 ◽

Author(s):

Keisuke Tabara ◽

Rina Kanda ◽

Kahori Sonoda ◽

Takuya Kubo ◽

Yuichi Murakami ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Acquired Resistance ◽

Mutant Gene ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

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