scholarly journals Association between atopic disease and anemia in pediatrics: a cross-sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kiyon Rhew ◽  
Jung Mi Oh
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Logistic Regression ◽  
Pediatric Patients ◽  
Inflammatory Diseases ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Atopic Diseases ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Atopic diseases, such as atopic dermatitis, allergic rhinitis, and asthma, are inflammatory diseases common in pediatric patients. This study investigated whether these inflammatory atopic diseases were associated with anemia in pediatrics. Methods A cross-sectional study was conducted using a pediatric dataset from the Health Insurance Review and Assessment Service (HIRA) of South Korea in 2016. Multivariable logistic regression, adjusting for demographic covariates was used for analyse the association between atopic disease and iron deficiency anemia (IDA). Results A total of 846,718 pediatric patients were included in the study. Of these, 19,594 (2.31%) had a diagnosis of IDA. The logistic regression analyses including covariates revealed there were association between atopic disease and IDA. The adjusted OR (aOR) of IDA was 1.42 (95% CI, 1.37–1.47) for atopic dermatitis, 1.25 (95% CI, 1.21–1.29) for allergic rhinitis, and 1.71 (95% CI, 1.65–1.76) for asthma. IDA was more prevalent in patients with multiple comorbid atopic diseases, with aOR of 1.30 (95% CI, 1.25–1.35), 1.81 (95% CI, 1.73–1.89), and 2.58 (95% CI, 2.43–2.73) for 1, 2, or 3 atopic diagnoses. There was no evidence of multicollinearity among covariates. Conclusions Our findings suggest that atopic disease was associated with IDA. Further study is needed to clarify the distinction between IDA and/or AI to better understand the cause of anemia in patients with inflammatory diseases.

scholarly journals Atopic Disease and Anemia in Korean Patients: Cross-Sectional Study with Propensity Score Analysis

2020 ◽  
Vol 17 (6) ◽  
pp. 1978
Author(s):  
Kiyon Rhew ◽  
Joshua D Brown ◽  
Jung Mi Oh
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Propensity Score ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Propensity Score Weighting ◽  
Increased Risk

Atopic disease is associated with chronic inflammation, and anemia has been reported in patients with inflammatory disorders such as rheumatoid arthritis, chronic obstructive pulmonary disease, and irritable bowel disease. The objective of this study was to determine whether atopic disease is associated with an increased risk of anemia. A cross-sectional study with propensity score weighting was conducted using a health insurance review agency claims dataset comprised of randomized patients who used the Korean national health system at least once in 2016. The association between atopic disease (asthma, atopic dermatitis, allergic rhinitis) and anemia (iron deficiency anemia (IDA) and/or anemia of inflammation (AI)) was examined. A total of 1,468,033 patients were included in this study. The IDA/AI prevalence was 3.1% (45,681 patients). After propensity score weighting, there were 46,958 and 45,681 patients in the non-anemic and anemic groups, respectively. The prevalence of IDA/AI in patients with atopic dermatitis, allergic rhinitis, or asthma had an odds ratio (OR) of 1.40 (95% confidence interval (CI), 1.33–1.48; p < 0.001), 1.17 (95% CI, 1.14–1.21; p < 0.001), and 1.32 (95% CI, 1.28–1.36; p < 0.001), respectively. In addition, the prevalence of IDA increased with higher numbers of atopic diseases. In conclusion, the prevalence of IDA/AI was higher in patients with atopic disease, even after adjusting for demographic characteristics and other risk factors. Further study is needed to distinguish between IDA and AI and to enhance understanding of the etiology of anemia in patients with inflammatory conditions.

Author response for "Clinical oral profile of pediatric patients with Atopic Dermatitis: A cross‐sectional study"

2020 ◽  
Author(s):  
Camila Stofella Sodré ◽  
Dennis de Carvalho Ferreira ◽  
Mayra Stambovsky Vieira ◽  
Fernanda Sampaio Calvalcante ◽  
Beatriz Stofel Braga ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pediatric Patients ◽  
Cross Sectional Study ◽  
Author Response ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Prevalence of atopic diseases in children with papular urticaria

2021 ◽  
Vol 49 (1) ◽  
pp. 62-67
Author(s):  
Mehmet Halil Celiksoy ◽  
Abdullah Hakan Ozmen ◽  
Erdem Topal
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Hypersensitivity Reaction ◽  
Medical Records ◽  
Pediatric Patients ◽  
Atopic Disease ◽  
Control Group ◽  
Atopic Diseases ◽  
Bed Bugs ◽  
Recurrent Wheezing

Background: Papular urticaria is a hypersensitivity reaction characterized by chronic and recurrent papular erythema. It occurs as a result of the bites of mosquitoes, fleas, bed bugs, and other insects; and it is generally seen in children. This study examines the prevalence of atopic diseases in patients with papular urticaria. Methods: The medical records of 130 pediatric patients with the diagnosis of papular urticaria between August 2017 and August 2019, whose disease progression was followed in two ter-tiary care centers, were reviewed retrospectively. The patients were divided into two groups: under 5 and above 5 years old. The prevalence of the atopic disease in children with papular urticaria was compared with those in age-matched controls without papular urticaria. Results: The study included 130 patients who were diagnosed with papular urticaria (64 males, 66 females, median age: 60 months). The prevalences of atopic disease, recurrent wheezing, and atopic dermatitis were higher in the group under 5 years old with papular urticaria than in the same-age control group (p = 0.001, 0.002, and 0.001, respectively). The prevalences of atopic disease, asthma, allergic rhinitis, and atopic dermatitis were higher in the group above 5 years old with papular urticaria than in the same-age control group (p = 0.001, 0.001, 0.001, and 0.007, respectively). Conclusions: Many children with papular urticaria are atopic children. These patients should be assessed not only in terms of papular urticaria but also in terms of comorbid atopic diseases.

scholarly journals Relationship Between Concomitant Atopic Diseases With Atopic Dermatitis Severity And Persistence.

2021 ◽  
Vol 6 (2) ◽  
pp. 43-47
Author(s):  
Adawiyah Jamil ◽  
Siew Wen Goh ◽  
Chon Sian Lee ◽  
Mohan Arumugam
Keyword(s):  
Atopic Dermatitis ◽  
Family History ◽  
Demographic Data ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Atopic Diseases ◽  
Cross Sectional ◽  
Face To Face ◽  
Tertiary Hospitals ◽  
History Of

Introduction: The atopic march consists of atopic dermatitis (AD), allergic rhinitis or sinusitis (AR), allergic conjunctivitis (AC) and bronchial asthma (BA). The influence of concomitant atopic diseases on AD is under-explored. We determined the relationship between personal and family history of atopic diseases with AD severity and persistence. Methods: A cross sectional study involving AD patients was performed at dermatology clinics of two tertiary hospitals. Inclusion criterion was all patients diagnosed with AD. Demographic data, personal and family history of atopy (BA, AR and AC) were obtained by face-to-face interview. AD severity was evaluated using Investigator’s Global Assessment (IGA). AD was considered persistent if continued beyond age 12 years. Results: Sixty patients aged 21.6±17.2 participated. There were 25(41.7%) with concomitant AR, 16(26.7%) BA and 12(20%) AC. Forty seven (78.3%) patients had family history of atopy, 25(41.7%) had eczema, 24(40%) AR, 19(31.7%) BA and 2(3.3%) AC. Patients with BA [OR=3.8, 95%CI 1.04 to 14.4)], BA and AR [OR=9.74, 95%CI 1.13 to 83.67) and family history of BA [OR= 4.00, 95%CI 1.20 to 13.27) were more likely to exhibit moderate-severe AD. Personal AR, AC and family history of AD and BA were significantly more prevalent in patients with persistent AD. Conclusions: AR was the most common atopic disease associated with AD. Family history of eczema and AR were common. Personal BA, BA with AR and family history of BA were predictors of severe AD. Personal AR, AC and family history of AD and BA were associated with AD persistence.

Clinical oral profile of pediatric patients with atopic dermatitis: A cross‐sectional study

Oral Diseases ◽  
2020 ◽  
Author(s):  
Camila Stofella Sodré ◽  
Dennis de Carvalho Ferreira ◽  
Mayra Stambovsky Vieira ◽  
Fernanda Sampaio Cavalcante ◽  
Beatriz Stofel Braga ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pediatric Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional
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