scholarly journals Prevalence of atopic diseases in children with papular urticaria

2021 ◽  
Vol 49 (1) ◽  
pp. 62-67
Author(s):  
Mehmet Halil Celiksoy ◽  
Abdullah Hakan Ozmen ◽  
Erdem Topal
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Hypersensitivity Reaction ◽  
Medical Records ◽  
Pediatric Patients ◽  
Atopic Disease ◽  
Control Group ◽  
Atopic Diseases ◽  
Bed Bugs ◽  
Recurrent Wheezing

Background: Papular urticaria is a hypersensitivity reaction characterized by chronic and recurrent papular erythema. It occurs as a result of the bites of mosquitoes, fleas, bed bugs, and other insects; and it is generally seen in children. This study examines the prevalence of atopic diseases in patients with papular urticaria. Methods: The medical records of 130 pediatric patients with the diagnosis of papular urticaria between August 2017 and August 2019, whose disease progression was followed in two ter-tiary care centers, were reviewed retrospectively. The patients were divided into two groups: under 5 and above 5 years old. The prevalence of the atopic disease in children with papular urticaria was compared with those in age-matched controls without papular urticaria. Results: The study included 130 patients who were diagnosed with papular urticaria (64 males, 66 females, median age: 60 months). The prevalences of atopic disease, recurrent wheezing, and atopic dermatitis were higher in the group under 5 years old with papular urticaria than in the same-age control group (p = 0.001, 0.002, and 0.001, respectively). The prevalences of atopic disease, asthma, allergic rhinitis, and atopic dermatitis were higher in the group above 5 years old with papular urticaria than in the same-age control group (p = 0.001, 0.001, 0.001, and 0.007, respectively). Conclusions: Many children with papular urticaria are atopic children. These patients should be assessed not only in terms of papular urticaria but also in terms of comorbid atopic diseases.

scholarly journals Nasal Cytology as a Marker of Atopy in Children

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Anna Mierzejewska ◽  
Anna Jung ◽  
Bolesław Kalicki
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Atopic Disease ◽  
Diagnostic Value ◽  
Control Group ◽  
Healthy Children ◽  
Atopic Diseases ◽  
Significant Group ◽  
Children With Asthma ◽  
Nasal Cytology

The aim of this study was to evaluate the cytological picture of nasal mucosa in children with atopic diseases and to determine the diagnostic value of the test for the diagnosis of atopic diseases. The study included 140 children from 4 months to 17 years old. Among children with a history of atopy, there were 30 children with atopic dermatitis, 30 children with asthma, and 46 children with allergic rhinitis. The control group consisted of 34 healthy children. The nasal scraping technique has been used to collect samples from the nasal cavity. The samples were evaluated under light microscope. Epithelial cells as well as infiltrating cells were assessed. The only statistically significant group of cells differentiating children with atopic disease and without atopy were eosinophils, which in children with atopy were significantly more common. Assuming a significant eosinophilia value of at least 5% of all cells in cytogram, the sensitivity of nasal cytology in allergic rhinitis was 52.2%, in asthma 33.3%, and in atopic dermatitis 13.3%. The specificity of the test in atopic diseases was 94.1%. It can be concluded that nasal cytology with eosinophilia assessment can be a useful tool for an early diagnosis of atopic disease in children.

scholarly journals Association between atopic disease and anemia in pediatrics: a cross-sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kiyon Rhew ◽  
Jung Mi Oh
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Logistic Regression ◽  
Pediatric Patients ◽  
Inflammatory Diseases ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Atopic Diseases ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Atopic diseases, such as atopic dermatitis, allergic rhinitis, and asthma, are inflammatory diseases common in pediatric patients. This study investigated whether these inflammatory atopic diseases were associated with anemia in pediatrics. Methods A cross-sectional study was conducted using a pediatric dataset from the Health Insurance Review and Assessment Service (HIRA) of South Korea in 2016. Multivariable logistic regression, adjusting for demographic covariates was used for analyse the association between atopic disease and iron deficiency anemia (IDA). Results A total of 846,718 pediatric patients were included in the study. Of these, 19,594 (2.31%) had a diagnosis of IDA. The logistic regression analyses including covariates revealed there were association between atopic disease and IDA. The adjusted OR (aOR) of IDA was 1.42 (95% CI, 1.37–1.47) for atopic dermatitis, 1.25 (95% CI, 1.21–1.29) for allergic rhinitis, and 1.71 (95% CI, 1.65–1.76) for asthma. IDA was more prevalent in patients with multiple comorbid atopic diseases, with aOR of 1.30 (95% CI, 1.25–1.35), 1.81 (95% CI, 1.73–1.89), and 2.58 (95% CI, 2.43–2.73) for 1, 2, or 3 atopic diagnoses. There was no evidence of multicollinearity among covariates. Conclusions Our findings suggest that atopic disease was associated with IDA. Further study is needed to clarify the distinction between IDA and/or AI to better understand the cause of anemia in patients with inflammatory diseases.

scholarly journals Risk factors for atopic diseases and recurrent respiratory tract infections in children

2020 ◽  
Author(s):  
Hannah Maria Kansen ◽  
Melanie A. Lebbink ◽  
Joeri Mul ◽  
Francine C. van Erp ◽  
Martine van Engelen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Atopic Disease ◽  
Atopic Diseases ◽  
Tract Infections ◽  
Shared Risk ◽  
Recurrent Respiratory Tract Infections

Abstract Background The simultaneous increased prevalence of atopic diseases and decreased prevalence of infectious diseases might point to a link between the two entities. Past work mainly focused on either atopic diseases or recurrent infections. We aim to investigate whether risk factors for atopic diseases (i.e. asthma, allergic rhinitis, atopic dermatitis and/or food allergy) differ from risk factors for recurrent respiratory tract infections (RRTIs) in children. Methods Cross-sectional data were used from 5516 children aged 1-18 years who participated in an Electronic Portal for children between 2011 and 2019. Univariable/multivariable logistic regression analyses were performed to determine risk factors for any atopic disease and RRTIs. Results Children aged ≥5 years were more likely to have any atopic disease (adjusted Odds Ratio, OR, 1.49-2.80) and less likely to have RRTIs (OR 0.77-0.82) compared to children aged <5 years. Female sex (OR 0.72; 95% CI 0.64-0.82), low birth weight (OR 0.74; 95% CI 0.56-0.98) and dog ownership (OR 0.79; 95% CI 0.66-0.95) reduced the odds of any atopic disease, but not of RRTIs. Day care attendance (OR 1.31; 95% CI 1.09-1.58) was associated with RRTIs, but not with atopic diseases. A family history of asthma, allergic rhinitis, atopic dermatitis and RRTIs was significantly associated with the same entity in children, with OR varying from 1.58 (95% CI 1.36-1.84) in allergic rhinitis to 2.19 (95% CI 1.85-2.60) in asthma. Conclusions Risk factors for atopic diseases are distinct from risk factors for RRTIs, suggesting that the changing prevalence of both entities is not related to shared risk factors.

scholarly journals Distribution of atopic conditions among attendants to specialized allergy center/ Kirkuk/ Iraqi

2020 ◽  
Vol 3 (2) ◽  
pp. 139-153
Author(s):  
Chinar Kanbar ◽  
Abdulameer Samad ◽  
Ali Galleb
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Environmental Factors ◽  
Skin Prick Test ◽  
House Dust ◽  
House Dust Mite ◽  
Atopic Disease ◽  
Atopic Diseases ◽  
Prick Test ◽  
Dust Mite

Atopy is a syndrome characterized by genetic tendency to develop allergic diseases, such as asthma, allergic rhinitis and atopic dermatitis. The risk factors of atopic diseases can be placed in two categories, namely host and environmental factors. The host factors of allergy include genetics, race, gender, age… etc. The environmental factors include exposure to environmental pollution and allergens. To define the distribution of atopic conditions (asthma, allergic rhinitis and atopic dermatitis) according to age, residence and available skin prick test. This cross-sectional study included (100) patients, representing research sample. It was conducted in specialized allergy center in Kirkuk city during the period from first January .2016 to the end of December 2016 All patients included in this study were referred from primary health centers, complaining from signs and symptoms of atopic diseases. Depending on medical history and clinical examinations, the sample was classified into (3) groups (asthma, allergic rhinitis and atopic dermatitis). Skin prick test was used to identify patients allergy to house dust mite and pollen. Regarding the distribution of samples according to residence, most patients (about 91%) were from urban areas compared with (9%) of them were from rural areas. Also, it was found that the frequency of atopic diseases decreases by age advancement. The frequency distribution of asthma, allergic rhinitis and atopic dermatitis was 49%, 26% and 25%, respectively. The skin test data revealed the frequency of 2 aeroallergen mite and pollen in all patients under study. .Hence, 65% were sensitive to house dust mite, 26% to pollen and 9% to both mite and pollen In conclusion this study confirmed that most patients complaining from atopic disease were from urban area. Also, the frequency of atopic diseases decreased by age advancement. The most common atopic disease was asthma followed by allergic rhinitis and atopic dermatitis. Most patients were sensitive to house dust mite.

scholarly journals Complementary feeding and food allergy, atopic dermatitis/eczema, asthma, and allergic rhinitis: a systematic review

2019 ◽  
Vol 109 (Supplement_1) ◽  
pp. 890S-934S ◽  
Author(s):  
Julie E Obbagy ◽  
Laural K English ◽  
Yat Ping Wong ◽  
Nancy F Butte ◽  
Kathryn G Dewey ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Food Allergy ◽  
Complementary Feeding ◽  
Atopic Disease ◽  
Study Data ◽  
Reverse Causality ◽  
Diet Diversity ◽  
Diagnostic Measures ◽  
Department Of Health

ABSTRACTBackgroundNutrition during infancy and toddlerhood may influence health and disease prevention across the life span. Complementary feeding (CF) starts when human milk or infant formula is complemented by other foods and beverages, beginning during infancy and continuing to age 24 mo.ObjectivesThe aim of this study was to describe systematic reviews conducted for the USDA and the Department of Health and Human Services Pregnancy and Birth to 24 Months Project to answer the following question: What is the relationship between the timing of the introduction of complementary foods and beverages (CFBs), or types and amounts of CFBs consumed, and the development of food allergy, atopic dermatitis/eczema, asthma, and allergic rhinitis?MethodsThe literature was searched using 4 databases (CINAHL, Cochrane, Embase, PubMed) to identify articles published from January 1980 to February 2017 that met predetermined inclusion criteria. For each study, data were extracted and risk of bias was assessed. The evidence was qualitatively synthesized to develop a conclusion statement, and the strength of the evidence was graded.ResultsThirty-one included articles addressed the timing of CFB introduction, and 47 articles addressed the types and amounts of CFBs consumed.ConclusionsModerate evidence suggests that there is no relationship between the age at which CF first begins and the risk of developing food allergy, atopic dermatitis/eczema, or childhood asthma. Limited to strong evidence, depending on the specific food, suggests that introducing allergenic foods in the first year of life (after 4 mo) does not increase the risk of food allergy and atopic dermatitis/eczema but may prevent peanut and egg allergy. There is not enough evidence to determine a relationship between diet diversity or dietary patterns and atopic disease. Research is needed to address gaps and limitations in the evidence on CF and atopic disease, including research that uses valid and reliable diagnostic measures and accounts for key confounders and potential reverse causality.

scholarly journals Atopic Disease and Anemia in Korean Patients: Cross-Sectional Study with Propensity Score Analysis

2020 ◽  
Vol 17 (6) ◽  
pp. 1978
Author(s):  
Kiyon Rhew ◽  
Joshua D Brown ◽  
Jung Mi Oh
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Propensity Score ◽  
Atopic Disease ◽  
Cross Sectional Study ◽  
Deficiency Anemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Propensity Score Weighting ◽  
Increased Risk

Atopic disease is associated with chronic inflammation, and anemia has been reported in patients with inflammatory disorders such as rheumatoid arthritis, chronic obstructive pulmonary disease, and irritable bowel disease. The objective of this study was to determine whether atopic disease is associated with an increased risk of anemia. A cross-sectional study with propensity score weighting was conducted using a health insurance review agency claims dataset comprised of randomized patients who used the Korean national health system at least once in 2016. The association between atopic disease (asthma, atopic dermatitis, allergic rhinitis) and anemia (iron deficiency anemia (IDA) and/or anemia of inflammation (AI)) was examined. A total of 1,468,033 patients were included in this study. The IDA/AI prevalence was 3.1% (45,681 patients). After propensity score weighting, there were 46,958 and 45,681 patients in the non-anemic and anemic groups, respectively. The prevalence of IDA/AI in patients with atopic dermatitis, allergic rhinitis, or asthma had an odds ratio (OR) of 1.40 (95% confidence interval (CI), 1.33–1.48; p < 0.001), 1.17 (95% CI, 1.14–1.21; p < 0.001), and 1.32 (95% CI, 1.28–1.36; p < 0.001), respectively. In addition, the prevalence of IDA increased with higher numbers of atopic diseases. In conclusion, the prevalence of IDA/AI was higher in patients with atopic disease, even after adjusting for demographic characteristics and other risk factors. Further study is needed to distinguish between IDA and AI and to enhance understanding of the etiology of anemia in patients with inflammatory conditions.

scholarly journals Role of Predatory Mites in Persistent Nonoccupational Allergic Rhinitis

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Paloma Poza Guedes ◽  
Inmaculada Sánchez Machín ◽  
Víctor Matheu ◽  
Víctor Iraola ◽  
Ruperto González Pérez
Keyword(s):  
Allergic Rhinitis ◽  
Provocation Test ◽  
Atopic Disease ◽  
Control Group ◽  
Clinical Role ◽  
Prick Test ◽  
Ige Response ◽  
Cheyletus Eruditus ◽  
Predator Mite

Mites can sensitize and induce atopic disease in predisposed individuals and are an important deteriorating factor in patients with allergic rhinitis, asthma, and atopic dermatitis. Although Pyroglyphidae mites have been extensively studied, very scarce reports are available on Cheyletidae spp. especially regarding human respiratory pathology. The main objective of the present study is to investigate the clinical role of this predator mite (Cheyletus eruditus) as a respiratory antigen in a selected sensitized human population. Fifty-two adult patients were recruited from the outpatient allergy clinic to assess their eligibility for the study. The thirty-seven subjects with persistent allergic rhinitis (PAR) who fulfilled the ARIA criteria had a positive IgE response confirmed by skin prick test (SPT) toC. eruditus. Only those individuals (37/47) with a positive SPT toC. eruditusshowed a positive nasal provocation test (NPT), while 10 patients with nonallergic mild-to-moderate persistent rhinitis,control group, had a negative NPT withC. eruditus. The present paper describes a new role for the predator miteCheyletus eruditusas a respiratory allergen in a selected subset of patients in a subtropical environment afflicted with persistent nonoccupational allergic rhinitis.

scholarly journals Clinical manifestations of childhood asthma persisting until the age of seven

2016 ◽  
Vol 44 (1) ◽  
pp. 1
Author(s):  
Rini Asterina ◽  
Sjawitri P Siregar ◽  
Bambang Madiyono ◽  
Bambang Supriyatno
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Childhood Asthma ◽  
Clinical Symptoms ◽  
Age Of Onset ◽  
Clinical Manifestations ◽  
Persistent Asthma ◽  
Cigarette Smoke Exposure ◽  
Atopic Diseases ◽  
Inclusion Criteria

Background Asthma is a chronic illness commonly found in chil-dren. We aimed to find out the clinical manifestations of childhoodasthma persisting until the age of seven and the influencing factors.Methods A review was performed at the outpatient clinic of theDepartment of Child Health Cipto Mangunkusumo Hospital Jakarta,from January 1992 to December 2001, on children with asthmawho still had symptoms until the age of seven.Results During the period of 10 years, there were 322 childrenwith clinical symptoms of asthma persisting until the age of 7. Onehundred and forty-six (45.3%) met the inclusion criteria, consistingof 75 (51.4%) boys and 71 (48.6%) girls. The average age was11.7 years. There were 101 (69.2%) patients with rare episodicasthma, 26.0% with frequent episodic asthma, and 4.8% with per-sistent asthma. Age of onset was mostly beyond 3 year-old (51%).Besides asthma, atopic diseases noted in these patients were al-lergic rhinitis in 85 (58.2%) and atopic dermatitis in 42 (28.8%).Logistic regression found that cigarette smoke exposure (adjustedOR 4.72, 95%CI 2.05;10.87, p=0.000), allergic rhinitis (adjustedOR 3.44, 95%CI 1.40;8.45, p=0.007), and atopic dermatitis (ad-justed OR 2.37, 95%CI 1.01;5.72, p=0.048) had significant asso-ciation with the degree of asthma.Conclusion Of 146 children who still had asthma until the age ofseven, there were 69% with rare episodic asthma, 26% with fre-quent episodic asthma, and 4.8% with persistent asthma. Factorspresumably influencing this manifestations were cigarette smokeexposure, allergic rhinitis, and atopic dermatitis

scholarly journals The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyo-Eun Kwon ◽  
Hye-Jin Ahn ◽  
Su Jin Jeong ◽  
Min Kyung Shin
Keyword(s):  
Atopic Dermatitis ◽  
Medical Records ◽  
Dermal Fibroblast ◽  
Allergic Diseases ◽  
Control Group ◽  
T Helper ◽  
Logistic Regression Models ◽  
Adolescents And Adults ◽  
Allergic Contact ◽  
Information Database

AbstractAtopic dermatitis (AD) is associated with allergic comorbidities, such as asthma, allergic rhinitis (AR), and allergic contact dermatitis (ACD). The etiology of keloid is largely unknown; however, AD and keloid share inflammatory pathways characterized by T-helper cell 2 cytokines and increased dermal fibroblast activity. The prevalence of keloids has been reported to increase in patients with AD, but it remains controversial. This study aimed to estimate the prevalence of keloids in patients with AD, and compare it with the prevalence of other comorbidities of AD. We assessed the Korean National Health Information Database and medical records including coexisting asthma, AR, and ACD. Single and multiple logistic regression models were created for keloids and each allergic disease. The prevalence of keloids was higher in the AD group than in the control group. Among patients with AD, adolescents and adults had a higher prevalence of keloids than infants and children. The risk of keloids was high with AD alone, and coexisting asthma significantly increased the risk. Similarly, the risk of keloids was higher in AR associated with AD and ACD associated with AD than in AD alone. Thus, among Koreans, patients with AD have a higher risk of keloid development, with coexisting allergic diseases increasing the risk.

scholarly journals Qualitative signs of digital dermatoglyphics as markers of diseases of atopic nature

2019 ◽  
pp. 5-12
Author(s):  
V. G. Cherkasov ◽  
О. Ye. Маievskyi ◽  
I. V. Serheta ◽  
I. M. Makarchuk ◽  
N. M. Smolko
Keyword(s):  
Allergic Rhinitis ◽  
Atopic Dermatitis ◽  
Bronchial Asthma ◽  
Young Women ◽  
Young Men ◽  
Statistical Processing ◽  
Random Pattern ◽  
Healthy Population ◽  
Atopic Diseases ◽  
Polygenic Inheritance

The lawfulness of the application of the method of dermatoglyphics in the study of atopic diseases is ensured by the polygenic inheritance of signs of dermatoglyphics, on the one hand, and the pathogenetic heterogeneity of these diseases, on the other hand, as well as high informative ability of signs of dermatoglyphics as markers of diseases of hereditary and multifactorial nature. The purpose of the study is to detect differences in qualitative signs of digital dermatoglyphics between patients with atopic dermatitis, allergic rhinitis and bronchial asthma. Primary indicators of digital dermatoglyphics of sick young men and young women of the Podillia region are taken from the data bank of the research center of the National Pirogov Memorial Medical University, Vinnytsya and were used in previous studies when compared with the practically healthy population of this region. Imprints were obtained by the method of “printing ink” by Gladkova T. D. By the method of Cummins H. and Midlo Ch. a dermatological study was performed for 320 young men and young women with allergic rhinitis (n=69), bronchial asthma (n=108) and atopic dermatitis (n=143). The frequency and location of 8 types of finger patterns were subject to analysis. Statistical processing of the obtained results was carried out in the package “Statistica 6.1” using nonparametric methods. The reliability of the difference in values between independent qualitative values was determined by the formula of Weber E. (1961). The specificity of the digital typology of atopic diseases is established, which is based on the differences in the frequency and location of the whorl, central pocket and arches between the young men, except those indicated - a random pattern between young women, patients with atopic dermatitis, bronchial asthma, allergic rhinitis. Additionally, when comparing young men, patients with allergic rhinitis with patients with bronchial asthma and atopic dermatitis - ulnar loop; for bronchial asthma with patients with allergic rhinitis and atopic dermatitis - lateral pocket loop (in young men) and ulnar, lateral pocket and double loops (in young women); when comparing young men, patients with atopic dermatitis with patients with bronchial asthma, and allergic rhinitis - a random pattern.

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