scholarly journals A 8- year Bangladeshi girl with disseminated histoplasmosis, presented as chronic liver disease with portal hypertension: a rare case report

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Luthfun Nahar ◽  
Md Benzamin ◽  
Naznin Sarkar ◽  
Urmi Roy ◽  
Kamrun Nahar ◽  
...  

Abstract Background Histoplasmosis is a rare infectious condition with mainly pulmonary involvement. Disseminated histoplasmosis may occur in immunocompromised condition. It can present in different ways but jaundice and ascites is very uncommon. Case presentation A 8- year old girl visited to department of pediatric gastroenterology & nutrition, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Child presented with fever, jaundice and abdominal distension for 2 ½ months. There was no history of contact with tuberculosis patient and travelling to kala-azar, malaria endemic zone and no history of previous jaundice, blood or blood product transfusion, history of sib death, family history of jaundice or neuropsychiatric disorder, significant weight loss. On general examination she was fretful, febrile, moderately icteric, mildly pale, vitally stable, severely wasted and moderately stunted, skin survey revealed infected scabies, BCG vaccine mark was absent, generalized lymphadenopathy, hepato-splenomegaly and ascites present. After evaluating the physical findings, several investigations was done including lymphnode biopsy, then the case was finally diagnosed as Disseminated histoplasmosis with portal hypertension. Child was treated with injectable Deoxycholate Amphotericin B for 28 days and improved on follow up. Conclusion We suggest that children presenting with fever, jaundice, lymphadenopathy and hepatosplenomegaly and portal hypertension, disseminated histoplasmosis can be one differential.

2012 ◽  
Vol 69 (7) ◽  
pp. 623-626
Author(s):  
Dusan Popovic ◽  
Milan Spuran ◽  
Lazar Davidovic ◽  
Tamara Alempijevic ◽  
Milenko Ugljesic ◽  
...  

Introduction. Arteriovenous fistula of the superior mesenteric blood vessels is a rare complicaton in abdominal surgery. Case report. We presented a 49-year-old man with cramplike abdominal pain, abdominal distension and weight loss symptoms, with a history of previous small bowel resection and right colectomy, due to Crohn disease, 16 years ago. Clinical examination revealed a paraumbilical pulsation with systolic murmur and thrill. Ultrasonography and computed tomography revealed cystic dilatation of the superior mesenteric vein, hepatomegaly and ascites. Upper endoscopy revealed grade I esophageal varices with portal hypertensive gastropathy. The diagnosis of arteriovenous fistula between superior mesenteric artery and vein was confirmed by angiogram of the superior mesenteric vessels and resection of the fistula was performed. Control examination after nine months showed no signs of portal hypertension. Conclusion. Early diagnosis and treatment of mesenteric blood vessel arteriovenous fistula prevents portal hypertension development and its complications.


2017 ◽  
Vol 4 (2) ◽  
pp. 669
Author(s):  
Kamal Nain Rattan ◽  
Gurupriya J. ◽  
Shruti Bansal ◽  
Rohit Kapoor ◽  
Roomi Yadav

Acquired colonic atresias are very rare but, are known in association with necrotizing enterocolitis. We report a case of a 4-month term male infant with recurrent episodes of abdominal distension, bilious vomiting and constipation off and on, without the history of necrotizing enterocolitis. Exploratory laparotomy was performed, an inflammatory mass with multiple dense interloop adhesions were found in the mid-transverse colon. These adhesions were lysed to identify the proximal dilated and distal blind end of the colon.  Rest of the gut was normal.  This case is unique for the fact that, it is a case of acquired colonic atresia without history of necrotizing enterocolitis, unlike other reported cases of acquired colonic atresia.


2020 ◽  
Vol 56 (5) ◽  
pp. 285
Author(s):  
Harry Cridge ◽  
Erin Brinkman ◽  
Patty Lathan

ABSTRACT A 4 mo old intact male Labrador retriever was referred to the authors’ institution for a 3 wk history of weight loss and progressive abdominal distension. Thoracic radiographs revealed sternal lymphadenopathy and a diffuse unstructured interstitial and bronchial pulmonary pattern. An abdominal ultrasound revealed multifocal lymphadenopathy, hepatosplenomegaly, and biliary duct dilation. Fine-needle aspirates of the spleen and liver revealed Histoplasma capsulatum organisms. Antifungal therapy was initiated with itraconazole and terbinafine. Repeat ultrasound examinations revealed resolving hepatosplenomegaly and resolving cystic duct dilation. Ultrasonographic findings mirrored a decrease in urine H capsulatum antigen levels. Histoplasmosis should be considered as a differential for unexplained biliary duct dilation or obstruction in dogs. Dogs with disseminated histoplasmosis should be monitored for this potential complication.


2018 ◽  
Vol 11 (4) ◽  
pp. 304-309
Author(s):  
Sayma Rahman Munmun ◽  
A. S. M. Bazlul Karim ◽  
Rezina Parveen ◽  
Md. Benazamin ◽  
Md. Shafikul Alam Tanim ◽  
...  

This article has no abstract. The first 100 words appear below: A 17-month-old girl, only issue of non-consanguineous parents, hailing from Sirajgonj, Bangladesh immunized as per EPI schedule got admitted to the inpatient department with the history of abdominal distension, jaundice, not growing well along with scaly skin lesion over scalp, chest, palm and sole for 9 months. She was reasonably well 9 months back. Then she developed abdominal distention which was increasing day-by-day associated with gradually deepening jaundice. There was also a history of irregular fever and cough for 1 month. Fever was high-grade irregular in nature, subsided by taking antipyretics in conjunction with non-productive cough. There was no history of contact with the tuberculosis patient, any surgery or dental procedure, family history of liver disease, but the history of one unit blood transfusion.


2018 ◽  
Vol 11 (2) ◽  
pp. 139
Author(s):  
Luthfun Nahar ◽  
A. S. M. Bazlul Karim ◽  
Md. Wahiduzzaman Mazumder ◽  
Zannatul Ferdous Sonia

<p>This article has no abstract. The first 100 words appear below:</p><p>A 5½ month old girl, 2<sup>nd</sup> issue of non-consanguineous parents from Jamalpur immunized as per EPI schedule, presented at the outpatient department with the history of abdominal distension since 2 months of her age which gradually increased day by day (Figure 1). She also had  a history of fever for 1 month which was low-grade, intermittent in nature but not documented and subsided after taking antipyretic. She had no history of cough, contact with tuberculosis patient, jaundice, pale stool, diarrhea, scanty micturition,  abdominal trauma or any history of surgery. Her elder brother was healthy and there was no family history of such type illness.</p>


2019 ◽  
Vol 12 (4) ◽  
pp. 204-210
Author(s):  
Nazmul Hassan ◽  
Mahmudul Hasan ◽  
Kaniz Fathema ◽  
Khondaker Mobasher ◽  
Fahmida Begum ◽  
...  

This article has no abstract. The first 100 words appear below: A 14-year-old boy, 4th issue of his non-consanguineous parents got admitted in the Department with the complaints of gradual abdominal distension and occasional abdominal pain since two years of his age. There was no history of jaundice, upper gastrointestinal bleeding, fever, contact with a known case of tuberculosis patient or family history of such type of illness. On examination, he was alert, anicteric, no facial dysmorphism, vitally stable, no stigmata of chronic liver disease and anthropometrically well thrived.


2018 ◽  
Vol 11 (4) ◽  
pp. 300-303
Author(s):  
Parisa Marjan ◽  
Md. Rukunuzzaman ◽  
A. S. M. Bazlul Karim ◽  
Mohuya Mondal ◽  
Hazera Akter

This article has no abstract. The first 100 words appear below: A 9-year-old girl of non-consanguineous parents presented at the outpatient department with the history of jaundice and abdominal distension for 20 days and respiratory distress for 7 days. She also complained of bloody vomiting without any melena. The mother gave the history of abdominal pain for 2 days which was diffuse in nature. Her menarche had not started yet. Her younger sister is healthy. She had no history of fever, constipation, family history of liver disease, sib death, contact with known tuberculosis patient, blood transfusion or parenteral medication. On examination, she was afebrile, moderately pale, dyspnea and leukonychia. Bilateral pedal edema was present.


2014 ◽  
Vol 14 (2) ◽  
pp. 201-203
Author(s):  
Chayan Kumar Singha ◽  
Eshita Biswas ◽  
Ferdous Jahan ◽  
Prodip Kumar Biswas

A case of disseminated histoplasmosis in a 62-year immunocompetent healthy male presenting as compressive myelopahty without any pulmonary involvement or travel to endemic zone is described. The patient presented with fever, dull ache pain in the back of the lower chest, weakness of both lower limbs with impairment of emptying of bowel and bladder, physical findings include raised temperature, generalized lymphadenopathy, nontender mild hepatomegaly, spastic paraplegia with sensory level up to D8 and local tenderness over D7 vertebra without any gibbus. Diagnosis was confirmed by presence of histoplasmacapsulatum in the lymph node and soft tissue from the spine. The particular interest of this paper is to present a case of disseminated histoplasmosis especially presenting as spastic paraplegia in an immunocompetent host without pulmonary involvement and illustrates the importance of recognizing the possibility of histoplasmosis in Bangladesh where mimickers of histoplasmosis like tuberculosis is extremely common.DOI: http://dx.doi.org/10.3329/jom.v14i2.19688 J Medicine 2013, 14(2): 201-203


2019 ◽  
Vol 98 (8) ◽  
pp. 326-327 ◽  

Introduction: The umbilical vein can become recanalised due to portal hypertension in patients with liver cirrhosis but the condition is rarely clinically significant. Although bleeding from this enlarged vein is a known complication, the finding of thrombophlebitis has not been previously described. Case report: We report the case of a 62-year-old male with a history of liver cirrhosis due to alcoholic liver disease presenting to hospital with epigastric pain. A CT scan of the patient’s abdomen revealed a thrombus with surrounding inflammatory changes in a recanalised umbilical vein. The patient was managed conservatively and was discharged home the following day. Conclusion: Thrombophlebitis of a recanalised umbilical vein is a rare cause of abdominal pain in patients with liver cirrhosis.


Author(s):  
M. A. Samad

Background: Ascites is one of the most important clinical syndromes, caused by multiple organ disorders, characterized by abdominal distension with accumulation of fluid of various colors and consistencies depending on the etiology that are encountered commonly in canine practice worldwide. Although it has been reported from different countries including India but it has not yet been documented from Bangladesh. Objectives: To evaluate the successful therapeutic management of a clinical case of ascites in dog supported with its brief review for its appropriate application Materials and Methods: A female Spitz dog two and half years old brought for treatment with the history of abdominal distension on 1st November 2009. Clinical examination, abdominocentesis and laboratory examination of ascitic fluid were used for the diagnosis of ascites in dog. Results: Clinical examination revealed dyspnea, discomfort, lethargy, weakness, pale mucous membrane, normal rectal temperature 103.2 0F and distended abdomen with fluid thrill on palpation. Examination of ascitic fluid revealed clear white fluid (pure transudate) which is mainly hepatic origin resulting portal hypertension and hypoproteinaemia. Treatment with restricted sodium diet, antibiotic (amoxicillin), diuretic (furosemide; Lasix, Sanofi Aventis) and vitamin B-complex and C- vitamin supplement with regular monitoring assisted in successful recovery. The recovered dog survived for next five years up to 2014 and then died due to other reasons. Conclusions: This clinical case record on canine ascites with successful treatment along with review especially on the methods of diagnosis and cause-wise treatment would certainly help the clinician for proper management of the clinical cases of canine ascites. Keywords: Ascites, Spitz dog, Diagnosis, SAAG, Therapeutic management, Brief review


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