scholarly journals Factors associated with intensive care admission in patients with lung cancer: a population-based observational study of 26, 731 patients

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Kathryn Puxty ◽  
Christopher H. Grant ◽  
Philip McLoone ◽  
Billy Sloan ◽  
Tara Quasim ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Intensive Care ◽  
Observational Study ◽  
Population Based ◽  
Intensive Care Admission ◽  
Factors Associated

scholarly journals What are the barriers to the completion of a home-based rehabilitation programme for patients awaiting surgery for lung cancer: a prospective observational study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e041907
Author(s):  
Heloise Catho ◽  
Sebastien Guigard ◽  
Anne-Claire Toffart ◽  
Gil Frey ◽  
Thibaut Chollier ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Living Alone ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Factors Associated ◽  
Home Based ◽  
Registration Number

ObjectivesHome-based rehabilitation programmes (H-RPs) could facilitate the implementation of pulmonary rehabilitation prior to resection for non-small cell lung cancer (NSCLC), but their feasibility has not been evaluated. The aim of this study was to identify determinants of non-completion of an H-RP and the factors associated with medical events occurring 30 days after hospital discharge.DesignA prospective observational study.InterventionAll patients with confirmed or suspected NSCLC were enrolled in a four-component H-RP prior to surgery: (i) smoking cessation, (ii) nutritional support, (iii) physiotherapy (at least one session/week) and (iv) home cycle-ergometry (at least three times/week).OutcomesThe H-RP was defined as ‘completed’ if the four components were performed before surgery.ResultsOut of 50 patients included, 42 underwent surgery (80% men; median age: 69 (IQR 25%–75%; 60–74) years; 64% Chronic Obstructive Pulmonary Disease (COPD); 29% type 2 diabetes). Twenty patients (48%) completed 100% of the programme. The median (IQR) duration of the H-RP was 32 (19; 46) days. Multivariate analysis showed polypharmacy (n=24) OR=12.2 (95% CI 2.0 to 74.2), living alone (n=8) (single vs couple) OR=21.5 (95% CI 1.4 to >100) and a long delay before starting the H-RP (n=18) OR=6.24 (95% CI 1.1 to 36.6) were independently associated with a risk of non-completion. In univariate analyses, factors associated with medical events at 30 days were H-RP non-completion, diabetes, polypharmacy, social precariousness and female sex.ConclusionFacing multiple comorbidities, living alone and a long delay before starting the rehabilitation increase the risk of not completing preoperative H-RP.Trial registration numberNCT03530059.

A Population-Based Observational Study of Intensive Care Unit–Related Outcomes. With Emphasis on Post-Hospital Outcomes

2015 ◽  
Vol 12 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Allan Garland ◽  
Kendiss Olafson ◽  
Clare D. Ramsey ◽  
Marina Yogendran ◽  
Randall Fransoo
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Observational Study ◽  
Population Based ◽  
Hospital Outcomes

scholarly journals P2.14-009 Assessing the Value of Radiotherapy for Lung Cancer in the Intensive Care Unit – A Population-based analysis

2017 ◽  
Vol 12 (11) ◽  
pp. S2178
Author(s):  
A. Louie ◽  
L. Li ◽  
K. Bray Jenkyn ◽  
B. Allen ◽  
A. Warner ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Population Based

scholarly journals Characteristics and outcomes of lung cancer patients after intensive care admission

2015 ◽  
Vol 16 (3) ◽  
pp. 239-239 ◽  
Author(s):  
K Hulse ◽  
T Quasim ◽  
D Morrison ◽  
P MacLoone ◽  
B Sloane ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Intensive Care ◽  
Cancer Patients ◽  
Intensive Care Admission ◽  
Lung Cancer Patients

scholarly journals CMET-42. USE OF STEREOTACTIC RADIOSURGERY AND OUTCOMES FOLLOWING RADIOTHERAPY FOR BRAIN METASTASES IN PATIENTS WITH PRIMARY LUNG CANCER – AN AUSTRALIAN POPULATION-BASED STUDY

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi60-vi61
Author(s):  
Wee Loon Ong ◽  
Morikatsu Wada ◽  
Farshad Foroudi
Keyword(s):  
Lung Cancer ◽  
Brain Metastases ◽  
Stereotactic Radiosurgery ◽  
Cox Regression ◽  
Primary Lung Cancer ◽  
Population Based ◽  
Mortality Data ◽  
Factors Associated ◽  
Geographical Variations ◽  
The Impact

Abstract INTRODUCTION We aim to evaluate the use of stereotactic radiosurgery (SRS) among lung cancer (LC) patients who received radiotherapy (RT) for brain metastases (BM), and the associated outcomes. METHODS This is a population-based cohort of LC patients who received RT for BM between 2013 and 2016, as captured in the Victorian Radiotherapy Minimum Dataset. Brain RT was classified as SRS (including multi-fraction stereotactic RT) and non-SRS. Mortality data was captured through data linkage with the Victorian Cancer Registry (VCR). The primary outcomes were: proportion of patients who had SRS for BM, and overall survival (OS) following brain RT. Multivariable logistic regression was used to evaluate factors associated with SRS use. Kaplan-Meier method was used to estimate OS. Multivariable Cox regression was used to evaluate factors associated with OS. RESULTS 1,002 LC patients were included in the study. 1,395 courses of RT for BM were delivered, of which one quarter (362/1,395) were SRS. Almost all SRS were delivered in metropolitan centres (347/362), and two-third in public institutions (235/362). In multivariate logistic regressions, increasing age (OR=0.91;95%CI=0.82–0.99;P=0.04) and treatment in regional centres (OR=0.13;95%CI=0.06–0.28;P< 0.001) were independently associated with lower likelihood of SRS use. Median follow-up was 3.3 months (IQR=1.3–7.8 months). 876 deaths were observed with 12-month OS of 16%. The 12-month OS for patients who had SRS were 38% vs. 12% in patient did not have SRS (P< 0.001). In multivariable Cox regressions, the use of SRS (HR=0.44,95%CI=0.37–0.54;P< 0.001) and female (HR=0.76;95%CI=0.67–0.87;P< 0.001) were associated with improved OS, while increasing age was associated with worse OS (HR=1.02;95%CI=1.01–1.03;P< 0.001). CONCLUSION This is the largest Australian study reporting on SRS use for BM in LC patients. We observed geographical variations in SRS use. We believe the impact of SRS use on OS is most likely due to patient selection for SRS.

scholarly journals Synchronous peritoneal metastases from lung cancer: incidence, associated factors, treatment and survival: a Dutch population-based study

2021 ◽  
Author(s):  
Robin J. Lurvink ◽  
Anouk Rijken ◽  
Checca Bakkers ◽  
Mieke J. Aarts ◽  
Peter W. A. Kunst ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Regression Analysis ◽  
Associated Factors ◽  
Population Based ◽  
Peritoneal Metastases ◽  
Tumour Stage ◽  
Population Based Study ◽  
Cox Regression Analysis ◽  
Factors Associated ◽  
Nodal Stage

AbstractPeritoneal metastases (PM) from lung cancer are rare and it is unknown how they affect the prognosis of patients with lung cancer. This population-based study aimed to assess the incidence, associated factors, treatment and prognosis of PM from lung cancer. Data from the Netherlands Cancer Registry were used. All patients diagnosed with lung cancer between 2008 and 2018 were included. Logistic regression analysis was performed to identify factors associated with the presence of PM. Cox regression analysis was performed to identify factors associated with the overall survival (OS) of patients with PM. Between 2008 and 2018, 129,651 patients were diagnosed with lung cancer, of whom 2533 (2.0%) patients were diagnosed with PM. The European Standardized Rate of PM increased significantly from 0.6 in 2008 to 1.4 in 2018 (p < 0.001). Age between 50 and 74 years, T3–4 tumour stage, N2–3 nodal stage, tumour morphology of a small cell lung cancer or adenocarcinoma, and the presence of systemic metastases were associated with the presence of PM. The median OS of patients with PM was 2.5 months. Older age, male sex, T3–4 tumour stage, N2–3 nodal stage, not receiving systemic treatment, and the presence of systemic metastases were associated with a worse OS. Synchronous PM were diagnosed in 2.0% of patients with lung cancer and resulted in a very poor survival.

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