scholarly journals Exertional intolerance and dyspnea with preserved lung function: an emerging long COVID phenotype?

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Grace Y. Lam ◽  
A. Dean Befus ◽  
Ronald W. Damant ◽  
Giovanni Ferrara ◽  
Desi P. Fuhr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Exercise Tolerance ◽  
Walk Test ◽  
Health Related Quality ◽  
Exertional Dyspnea ◽  
Distinct Phenotype ◽  
Related Quality ◽  
Health Related ◽  
Poor Functional Status

AbstractThe COVID-19 pandemic has resulted in significant acute morbidity and mortality worldwide. There is now a growing recognition of the longer-term sequelae of this infection, termed “long COVID”. However, little is known about this condition. Here, we describe a distinct phenotype seen in a subset of patients with long COVID who have reduced exercise tolerance as measured by the 6 min walk test. They are associated with significant exertional dyspnea, reduced health-related quality of life and poor functional status. However, surprisingly, they do not appear to have any major pulmonary function abnormalities or increased burden of neurologic, musculoskeletal or fatigue symptoms.

scholarly journals Efek program manajemen diri pada pasien penyakit paru obstruktif kronik : Systematis review

2019 ◽  
Vol 4 (2) ◽  
Author(s):  
Harni Harniati ◽  
Syahrul Syahrul ◽  
Takdir Tahir
Keyword(s):  
Quality Of Life ◽  
Exercise Capacity ◽  
Self Management ◽  
Walk Test ◽  
Health Related Quality ◽  
Lung Capacity ◽  
Copd Patients ◽  
Related Quality ◽  
Health Related

ABSTRACTBackground: Self-management programs are very important in the care of patients with COPD as an independent intervention in an effort to improve health status. Aim: Of this systematic review is to find out the form of self-management intervention in COPD patients, an instrument to measure the outcomes of self-management and the effects of self-management programs in COPD patients. Methods: Used are electronic data bases from journals published through ProQuest, PubMed., And ScienceDirect. Results: Of a review of 9 selected journals stated that self-management programs had an influence on increasing lung capacity, exercise capacity and health-related quality of life compared to patients who experienced standard care. The research instrument was used to measure lung capacity using spirometry, Exercise capacity used a six-minute walking distance (6MWD), Incremental Shuttle Walk Test (ISWT) and the Endurance Shuttle Walk Test (ESWT), and health-related quality of life measured by St George Respiratory Questionnaire (SGRQ). The results showed that the effects of self-management programs benefited in the quality of care, reduced the number of days of hospital care and did not increase the number of deaths. Conclusion: Self-management programs in COPD patients provide the ability to manage disease so that it can increase lung capacity, exercise capacity and quality of life related to health. Keywords: Chronic obstructive pulmonary disease, exercise capasity, lung   capacity self management program, quality of life

scholarly journals Diaphragmatic ultrasound findings correlate with dyspnea, exercise tolerance, health-related quality of life and lung function in patients with fibrotic interstitial lung disease

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Pauliane Vieira Santana ◽  
Leticia Zumpano Cardenas ◽  
André Luis Pereira de Albuquerque ◽  
Carlos Roberto Ribeiro de Carvalho ◽  
Pedro Caruso
Keyword(s):  
Quality Of Life ◽  
Interstitial Lung Disease ◽  
Lung Function ◽  
Exercise Tolerance ◽  
Healthy Controls ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Lower Hrqol

Abstract Background Fibrotic interstitial lung disease (FILD) patients are typically dyspneic and exercise-intolerant with consequent impairment of health-related quality of life (HRQoL). Respiratory muscle dysfunction is among the underlying mechanisms of dyspnea and exercise intolerance in FILD but may be difficult to diagnose. Using ultrasound, we compared diaphragmatic mobility and thickening in FILD cases and healthy controls and correlated these findings with dyspnea, exercise tolerance, HRQoL and lung function. Methods We measured diaphragmatic mobility and thickness during quiet (QB) and deep breathing (DB) and calculated thickening fraction (TF) in 30 FILD cases and 30 healthy controls. We correlated FILD cases’ diaphragmatic findings with dyspnea, exercise tolerance (six-minute walk test), lung function and HRQoL (St. George’s Respiratory Questionnaire). Results Diaphragmatic mobility was similar between groups during QB but was lower in FILD cases during DB when compared to healthy controls (3.99 cm vs 7.02 cm; p <  0.01). FILD cases showed higher diaphragm thickness during QB but TF was lower in FILD when compared to healthy controls (70% vs 188%, p <  0.01). During DB, diaphragmatic mobility and thickness correlated with lung function, exercise tolerance and HRQoL, but inversely correlated with dyspnea. Most FILD cases (70%) presented reduced TF, and these patients had higher dyspnea and exercise desaturation, lower HRQoL and lung function. Conclusion Compared to healthy controls, FILD cases present with lower diaphragmatic mobility and thickening during DB that correlate to increased dyspnea, decreased exercise tolerance, worse HRQoL and worse lung function. FILD cases with reduced diaphragmatic thickening are more dyspneic and exercise-intolerant, have lower HRQoL and lung function.

OC03_04 Relationship Between Six Minute Walk Test and Health-Related Quality of Life of Heart Failure Patients

Global Heart ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e4
Author(s):  
V. Peláez-Hernández ◽  
R. Pablo-Santiago ◽  
A. Orea-Tejeda ◽  
E. Pérez-Cabañas ◽  
J. Pineda-Juárez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Walk Test ◽  
Health Related Quality ◽  
Heart Failure Patients ◽  
Six Minute Walk Test ◽  
Related Quality ◽  
Health Related ◽  
Minute Walk

scholarly journals Διαταραχές της αναπνοής στον ύπνο και ποιότητα ζωής σε ασθενείς με διάχυτες διάμεσες πνευμονοπάθειες

2017 ◽  
Author(s):  
Μαρία Μαυρουδή
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Walk Test ◽  
Health Related Quality ◽  
Short Form 36 ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Οι ΔΔΠ είναι χρόνιες και περιοριστικού τύπου πνευμονοπάθειες με υψηλή νοσηρότητα, θνησιμότητα και κακή ποιότητα ζωής. Η συχνότητα και οι συνέπειες των διαταραχών του ύπνου καθώς και οι αλλαγές στη ποιότητα ζωής των ασθενών αυτών αποτελεί έναν τομέα έρευνας σε εξέλιξη, ωστόσο υπάρχουν σημαντικές αλληλοσυγκρουόμενες απόψεις μεταξύ παλαιότερων και πιο πρόσφατων μελετών.Σκοπός της παρούσας μελέτης ήταν η διερεύνηση της ύπαρξης των διαταραχών του ύπνου στην ΙΠΙ και τη σαρκοείδωση καθώς και η αξιολόγηση της ποιότητας ζωής των ασθενών αυτών. Επίσης πραγματοποιήθηκε συσχέτιση των παραμέτρων του ύπνου με τις παραμέτρους τις ποιότητας ζωής, με σκοπό να αξιολογηθεί κατά πόσο οι διαταραχές του ύπνου επηρεάζουν την ποιότητα ζωής και την καθημερινότητα των ασθενών αυτών. Συμπεριλήφθηκαν σαράντα ασθενείς, 19 με ΙΠΙ (11 άντρες και 8 γυναίκες) και 21 ασθενείς με σαρκοείδωση σταδίου II / III (7 άντρες και 14 γυναίκες). Έγινε σύγκριση με 15 υγιή άτομα χωρίς διαταραχές στον ύπνο, αντίστοιχης ηλικίας και ΒΜΙ με τους ασθενείς. Κατά τη διάρκεια της επίσκεψής τους καταγράφηκε πλήρες ιστορικό και έγινε κλινική εξέταση. Tα δεδομένα των ασθενών περιλάμβαναν στοιχεία από το ατομικό και ιατρικό ιστορικό του ασθενούς, φύλο, ηλικία, ΒΜΙ, κλινικά σημεία, συνοδά νοσήματα και φαρμακευτική αγωγή και τα αποτελέσματα της μελέτης ύπνου. Όλοι οι ασθενείς προσκόμισαν πρόσφατη σπιρομέτρηση με διάχυση η οποία εμφάνιζε περιοριστικού τύπου πνευμονοπάθεια και μείωση της διάχυσης, ιδιαίτερα στους ασθενείς με ΙΠΙ, και υποβλήθηκαν σε δοκιμασία βάδισης 6 λεπτών (6 min walk test 6MWT). Οι ασθενείς και οι μάρτυρες πραγματοποίησαν νυχτερινή πολυπνογραφία και συμπλήρωσαν τα ερωτηματολόγια Epworth, Berlin και Stop-Bang. Προκειμένου να αξιολογηθεί η ποιότητα ζωής, όλοι οι συμμετέχοντες συμπλήρωσαν το ερωτηματολόγιο Short-Form 36 (SF-36). Από τους ασθενείς με ΙΠΙ, το 68% διαγνώστηκε με ήπια αποφρακτική άπνοια ύπνου 5,2% με μέτρια έως σοβαρή, 5,2% με σοβαρό ΣΑΑΥ και 21% χωρίς αποφρακτική άπνοια ύπνου. Από τους ασθενείς με σαρκοείδωση, 52,4% διαγνώστηκαν με ήπιο ΣΑΑΥ και 4,8% με μέτριο. Το υπόλοιπο 42,8% δεν παρουσίασε ΣΑΑΥ. Η ποιότητα ζωής που σχετίζεται με την υγεία (Health Related Quality of Life HRQL) τόσο στους ασθενείς με ΙΠΙ όσο και στους ασθενείς με σαρκοείδωση παρουσίασε διαταραχές ειδικά στους τομείς της σωματικής υγείας και του βαθμού ανεξαρτησίας στην καθημερινότητά τους, σε σύγκριση με την ομάδα ελέγχου. Οι ασθενείς με ΙΠΙ παρουσίασαν θετική συσχέτιση του ΑΗΙ με το ερωτηματολόγιο Epworth, γεγονός που υποδεικνύει ότι η ημερήσια υπνηλία, που παρουσιάζουν οι ασθενείς αυτοί, οφείλεται στην κακή ποιότητα ύπνου. Στους ασθενείς με ΙΠΙ και σαρκοείδωση που ελέγχθηκαν στη παρούσα μελέτη, η αποφρακτική άπνοια στον ύπνο ήταν συχνή και ήπιας βαρύτητας. Η έγκαιρη και αξιόπιστη διάγνωση των διαταραχών του ύπνου και ιδιαίτερα του ΣΑΑΥ σε ασθενείς με ΙΠΙ και σαρκοείδωση και η βελτίωση της ποιότητας ζωής τους πρέπει να αποτελεί πρωταρχικό στόχο των θεραπόντων ιατρών. Το ερωτηματολόγιο SF-36, μόνο του ή σε συνδυασμό με άλλα ερωτηματολόγια ειδικά σχεδιασμένα για τις ασθένειες αυτές, αποτελεί ένα χρήσιμο και επικυρωμένο εργαλείο για την αξιολόγηση της ποιότητας ζωής των ασθενών αυτών.

Physical Fitness and Health-related Quality of Life in Patients with Colorectal Cancer

2021 ◽  
Author(s):  
Luisa Soares-Miranda ◽  
Alejandro Lucia ◽  
Marco Silva ◽  
Armando Peixoto ◽  
Rosa Ramalho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Health Status ◽  
Walk Test ◽  
Health Related Quality ◽  
Chair Stand ◽  
Related Quality ◽  
Health Related ◽  
Colorectal Cancer Patients

AbstractColorectal cancer is now a frequently treatable illness for most and a chronic disease for many. The number of people living with a diagnosis of colorectal cancer is thus expected to rise. Yet even after successful treatment, colorectal cancer survivors, mostly the elderly, frequently experience health problems and impaired health-related quality of life. We investigated the cross-sectional association between physical fitness, measured with the 6-min walk test, 30-second chair-stand test, and isometric handgrip strength, as well as health-related quality of life, in a cohort of colorectal cancer patients (n=71, mean [SD] age 67±10 years, 63% men; 35, 39 and 25% in stages I, II and III, respectively). Greater performance in the 6-minute walk test and 30-second chair-stand test was associated with higher levels of global health status (p<0.001, p=0.001 respectively), higher functioning (p<0.001) and lower levels of symptomatology (p<0.001; pain and fatigue). Additionally, greater 6-min walk test performance was associated with a better cognitive function (p=0.005). Our results suggest that greater aerobic fitness and lower-extremity muscle strength are cross-sectionally associated with higher levels of global health status, higher functioning and lower levels of symptomatology such as pain and fatigue in colorectal cancer patients.

scholarly journals Effect of home based pulmonary rehabilitation on health related quality of life in COPD patients

2018 ◽  
Vol 6 (11) ◽  
pp. 3731
Author(s):  
John Mathew ◽  
Jayaprakash Balakrishnan ◽  
Sanjeev Nair
Keyword(s):  
Quality Of Life ◽  
Pulmonary Rehabilitation ◽  
Exercise Tolerance ◽  
Research Work ◽  
Pulmonary Medicine ◽  
Health Related Quality ◽  
Home Based ◽  
Related Quality ◽  
Health Related

Background: Pulmonary rehabilitation is a proven strategy in the management of COPD, it’s a neglected area in our part of world and there are very few studies on home based pulmonary rehabilitation in COPD in our scenario and hence we evaluated the effectiveness of such a strategy. Aim of the research work was to study the effectiveness of home based pulmonary rehabilitation on health related quality of life, exercise tolerance, depression levels and perceived dyspnea as assessed by SGRQ (St. George Respiratory Questionnaire), 6MWTD (Six-Minute Walk Test distance), PHQ-9 (Patient Health Questionnaire-9), Modified Borg scale respectively.Methods: Patients attending the Department of Pulmonary Medicine, Medical College Trivandrum, diagnosed as COPD based on GOLD guidelines who fulfil the inclusion and exclusion criteria were studied from January 2013 to June 2014. Patients were educated about the disease and need for rehabilitation, advised smoking cessation, nutritional modification. Breathing exercise, upper limb and lower limb exercises given for 6 weeks in a structured manner and followed up in every second week and analyzed using paired t- test. Pre and post rehabilitation assessment included the SGRQ, 6MWTD, PHQ-9, Modified Borg dyspnea scale was done.Results: Around 40 patients had completed 6weeks of rehabilitation. There was a statistically and clinically significant improvement in quality of life, exercise tolerance, perceived dyspnoea was seen along with decrease in level of depression.Conclusions: Home based pulmonary rehabilitation is a feasible alternative to institution based rehabilitation in the management of COPD and is associated with significant benefit.

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