scholarly journals Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Svetlana Skolekova ◽  
Miroslava Matuskova ◽  
Martin Bohac ◽  
Lenka Toro ◽  
Erika Durinikova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Antitumor Effect

scholarly journals Erratum to: Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells

2016 ◽  
Vol 14 (1) ◽  
Author(s):  
Svetlana Skolekova ◽  
Miroslava Matuskova ◽  
Martin Bohac ◽  
Lenka Toro ◽  
Erika Durinikova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Antitumor Effect

Bone Marrow/Bone Pre-Metastatic Niche For Breast Cancer Cells Colonization: The Role Of Mesenchymal Stromal Cells

2021 ◽  
pp. 103416
Author(s):  
M.C. Sanmartin ◽  
F.R. Borzone ◽  
M.B. Giorello ◽  
N. Pacienza ◽  
G. Yannarelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Metastatic Niche

Interaction of human adipose tissue-derived mesenchymal stromal cells with breast cancer cells

Neoplasma ◽  
2011 ◽  
Vol 58 (5) ◽  
pp. 361-370 ◽  
Author(s):  
L. KUCEROVA ◽  
M. KOVACOVICOVA ◽  
S. POLAK ◽  
M. BOHAC ◽  
J. FEDELES ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adipose Tissue ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Human Adipose Tissue

Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell–cell interaction

2013 ◽  
Vol 319 (18) ◽  
pp. 2770-2780 ◽  
Author(s):  
Mika Pietilä ◽  
Petri Lehenkari ◽  
Paula Kuvaja ◽  
Mika Kaakinen ◽  
Sunil C. Kaul ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quantum Dot ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Cell Interaction ◽  
Human Mesenchymal Stromal Cells ◽  
Cell Cell

Breast cancer cells and bone marrow mesenchymal stromal cells: a regulated modulation of the breast tumor in the context of immune response

2016 ◽  
Vol 66 (2) ◽  
pp. 129-139 ◽  
Author(s):  
Mehdi Najar ◽  
Hussein Fayyad-Kazan ◽  
Wissam H. Faour ◽  
Bassam Badran ◽  
Fabrice Journe ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Immune Response ◽  
Cancer Cells ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Breast Tumor ◽  
Breast Cancer Cells

A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructures reveals complex tumour–stroma interactions

Lab on a Chip ◽  
2017 ◽  
Vol 17 (16) ◽  
pp. 2852-2860 ◽  
Author(s):  
Qihui Fan ◽  
Ruchuan Liu ◽  
Yang Jiao ◽  
Chunxiu Tian ◽  
James D. Farrell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Invasive Breast Cancer ◽  
Stromal Cells ◽  
Breast Cancer Cells ◽  
Microfluidic System ◽  
Tumour Stroma ◽  
Collagen Hydrogel

A 3-D microfluidic system consisting of microchamber arrays embedded in a collagen hydrogel with tunable biochemical gradients was constructed for investigating interactions between invasive breast cancer cells and stromal cells.

Application of digital holographic tumography in antitumor effect of cantharides complex on 4T1 breast cancer cells

2021 ◽  
Vol 60 (12) ◽  
pp. 3365
Author(s):  
Chen-Wen Lu ◽  
Andrey V. Belashov ◽  
Anna A. Zhikhoreva ◽  
Irina V. Semenova ◽  
Chau-Jern Cheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Antitumor Effect ◽  
4T1 Breast Cancer

scholarly journals Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257298
Author(s):  
Joohyun Woo ◽  
Jong Bin Kim ◽  
Taeeun Cho ◽  
Eun Hye Yoo ◽  
Byung-In Moon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Cell Lines ◽  
Combination Treatment ◽  
Breast Cancer Cells ◽  
Antitumor Effect ◽  
Beclin 1 ◽  
Her2 Positive ◽  
Phosphorylated Akt ◽  
Positive Breast Cancer

The response rate to treatment with trastuzumab (Tz), a recombinant humanized anti-HER2 monoclonal antibody, is only 12–34% despite demonstrated effectiveness on improving the survival of patients with HER2-positive breast cancers. Selenium has an antitumor effect against cancer cells and can play a cytoprotective role on normal cells. This study investigated the effect of selenium on HER2-positive breast cancer cells and the mechanism in relation to the response of the cells to Tz. HER2-positive breast cancer cell lines, SK-BR-3 as trastuzumab-sensitive cells, and JIMT-1 as Tz-resistant cells were treated with Tz and sodium selenite (selenite). Cell survival rates and expression of Her2, Akt, and autophagy-related proteins, including LC3B and beclin 1, in both cell lines 72 h after treatment were evaluated. Significant cell death was induced at different concentrations of selenite in both cell lines. A combined effect of selenite and Tz at 72 h was similar to or significantly greater than each drug alone. The expression of phosphorylated Akt (p-Akt) was decreased in JIMT-1 after combination treatment compared to that after only Tz treatment, while p-Akt expression was increased in SK-BR-3. The expression of beclin1 increased particularly in JIMT-1 after only Tz treatment and was downregulated by combination treatment. These results showed that combination of Tz and selenite had an antitumor effect in Tz-resistant breast cancer cells through downregulation of phosphorylated Akt and beclin1-related autophagy. Selenite might be a potent drug to treat Tz-resistant breast cancer by several mechanisms.

scholarly journals Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells

Oncogene ◽  
2009 ◽  
Vol 28 (30) ◽  
pp. 2745-2755 ◽  
Author(s):  
M Walter ◽  
S Liang ◽  
S Ghosh ◽  
P J Hornsby ◽  
R Li
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Stromal Cells ◽  
Interleukin 6 ◽  
Breast Cancer Cells ◽  
Migration And Invasion ◽  
Adipose Stromal Cells
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