scholarly journals Aerobic exercise training prevents impairment in renal parameters and in body composition of rats fed a high sucrose diet

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Jaqueline A. de Souza ◽  
Angélica B. Gonçalves Pinto ◽  
Emerson C. de Oliveira ◽  
Daniel B. Coelho ◽  
Nádia L. Totou ◽  
...  
Keyword(s):  
Body Composition ◽  
Creatinine Clearance ◽  
The Body ◽  
Aerobic Exercise Training ◽  
Renal Cells ◽  
Swimming Training ◽  
Urinary Creatinine ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

Abstract Objective This study aimed to evaluate the effect of swimming training (T) on the renal system and body composition parameters in young animals treated with a high sucrose diet (SUD) during 12 weeks. Results The SUD impaired the physical performance, increased the body adiposity index (BAI), Lee index (LI) and retroperitoneal adipose tissue (RAT) weight, plasma creatinine and number renal cells nuclei, decreased urinary volume and urinary creatinine excretion besides creatinine clearance. The T reversed the increased the BAI, LI, RAT weight, plasma and urinary creatinine, creatinine clearance and number renal cells nuclei in addition to promoting decrease in urinary protein excretion. This study found that eight weeks of swimming physical training protected renal function and restored normal glomerular filtration rate (GFR) values. Swimming training also contributed to prevention of the onset of a renal inflammatory process and caused a decrease in the risk of development of obesity promoted by SUD decreasing the body composition parameters (BAI, LI, and RAT weight).

scholarly journals Aerobic Exercise Training Prevents Impairment in Renal Parameters and in Body Composition of Rats Fed a High Sucrose Diet.

2021 ◽  
Author(s):  
Jaqueline Aparecida Souza ◽  
Angélica Barbosa Gonçalves Pinto ◽  
Emerson Cruz Oliveira ◽  
Daniel B. Coelho ◽  
Nádia Lúcia Totou ◽  
...  
Keyword(s):  
Body Composition ◽  
Creatinine Clearance ◽  
The Body ◽  
Aerobic Exercise Training ◽  
Renal Cells ◽  
Swimming Training ◽  
Retroperitoneal Adipose Tissue ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

Abstract Objective: This study aimed to evaluate the effect of swimming training (T) on the renal system and body composition parameters in young animals treated with a high sucrose diet (SUD) during 12 weeks.Results: The SUD impaired the physical performance, increased the body adiposity index (BAI), Lee index (LI) and retroperitoneal adipose tissue (RAT) weight, proteinuria, plasma creatinine and number renal cells nuclei, decreased urinary volume and creatinine besides creatinine clearance. The T reversed the increased the BAI, LI, RAT weight, plasma and urinary creatinine, creatinine clearance and number renal cells nuclei. This study found that eight weeks of swimming physical training protected renal function and restored normal glomerular filtration rate (GFR) values. Swimming training also contributed to prevention of the onset of a renal inflammatory process and caused a decrease in the risk of development of obesity promoted by SUD decreasing the body composition parameters (BAI, LI, and RAT weight).

scholarly journals Impact of MR on mature adipocytes in high-fat/high-sucrose diet-induced obesity

2018 ◽  
Vol 239 (1) ◽  
pp. 63-71 ◽  
Author(s):  
Tomoaki Hayakawa ◽  
Tomomi Minemura ◽  
Toshiharu Onodera ◽  
Jihoon Shin ◽  
Yosuke Okuno ◽  
...  
Keyword(s):  
Liver Weight ◽  
The Body ◽  
Minor Role ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
A Minor ◽  
High Sucrose

Active glucocorticoid levels are elevated in the adipose tissue of obesity due to the enzyme 11 beta-hydroxysteroid dehydrogenase type 1. Glucocorticoids can bind and activate both glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), and pharmacological blockades of MR prevent high-fat diet-induced obesity and glucose intolerance. To determine the significance of MR in adipocytes, we generated adipocyte-specific MR-knockout mice (AdipoMR-KO) and fed them high-fat/high-sucrose diet. We found that adipocyte-specific deletion of MR did not affect the body weight, fat weight, glucose tolerance or insulin sensitivity. While liver weight was slightly reduced in AdipoMR-KO, there were no significant differences in the mRNA expression levels of genes associated with lipogenesis, lipolysis, adipocytokines and oxidative stress in adipose tissues between the control and AdipoMR-KO mice. The results indicated that MR in mature adipocytes plays a minor role in the regulation of insulin resistance and inflammation in high-fat/high-sucrose diet-induced obese mice.

scholarly journals Maternal exercise modifies body composition and energy substrates handling in male offspring fed a high-fat/high-sucrose diet

2017 ◽  
Vol 595 (23) ◽  
pp. 7049-7062 ◽  
Author(s):  
Charline Quiclet ◽  
Hervé Dubouchaud ◽  
Phanélie Berthon ◽  
Hervé Sanchez ◽  
Guillaume Vial ◽  
...  
Keyword(s):  
Body Composition ◽  
Male Offspring ◽  
High Fat ◽  
Energy Substrates ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
Maternal Exercise ◽  
High Sucrose

Hepatic Transcriptomic Signature of High-Sucrose Diet in Nonobese Model of Metabolic Syndrome and Prediabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1723-P
Author(s):  
IRENA MARKOVÁ ◽  
MARTINA HÜTTL ◽  
HANA MALINSKA ◽  
ONDREJ SEDA ◽  
LUDMILA KAZDOVA
Keyword(s):  
Metabolic Syndrome ◽  
Sucrose Diet ◽  
Transcriptomic Signature ◽  
High Sucrose Diet ◽  
High Sucrose

Motor learning impairment in rats under a high sucrose diet

2021 ◽  
Vol 234 ◽  
pp. 113384
Author(s):  
Nayely Flores-Fuentes ◽  
Carolina Hernandez-Cruz ◽  
Karina Bermeo ◽  
Antonio Barajas-Martinez ◽  
Valeria Nayely Hernandez-Serratos ◽  
...  
Keyword(s):  
Motor Learning ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
Learning Impairment ◽  
High Sucrose

scholarly journals Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Sang Hyuk Lee ◽  
Eunjoo Cho ◽  
Sung-Eun Yoon ◽  
Youngjoon Kim ◽  
Eun Young Kim
Keyword(s):  
Locomotor Behavior ◽  
Sensory Inputs ◽  
Sucrose Diet ◽  
High Nutrient ◽  
Intracellular Ca ◽  
High Sucrose Diet ◽  
Locomotor Activities ◽  
Locomotor Behaviors ◽  
High Sucrose ◽  
Over Time

AbstractMetabolism influences locomotor behaviors, but the understanding of neural curcuit control for that is limited. Under standard light-dark cycles, Drosophila exhibits bimodal morning (M) and evening (E) locomotor activities that are controlled by clock neurons. Here, we showed that a high-nutrient diet progressively extended M activity but not E activity. Drosophila tachykinin (DTk) and Tachykinin-like receptor at 86C (TkR86C)-mediated signaling was required for the extension of M activity. DTk neurons were anatomically and functionally connected to the posterior dorsal neuron 1s (DN1ps) in the clock neuronal network. The activation of DTk neurons reduced intracellular Ca2+ levels in DN1ps suggesting an inhibitory connection. The contacts between DN1ps and DTk neurons increased gradually over time in flies fed a high-sucrose diet, consistent with the locomotor behavior. DN1ps have been implicated in integrating environmental sensory inputs (e.g., light and temperature) to control daily locomotor behavior. This study revealed that DN1ps also coordinated nutrient information through DTk signaling to shape daily locomotor behavior.

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