scholarly journals Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Mi Kyeong Lee ◽  
◽  
Cheng-Jian Xu ◽  
Megan U. Carnes ◽  
Cody E. Nichols ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Air Pollution ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Korean Adults ◽  
Genome Wide ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals Long-term low-level ambient air pollution exposure and risk of lung cancer – A pooled analysis of 7 European cohorts

2021 ◽  
Vol 146 ◽  
pp. 106249 ◽  
Author(s):  
Ulla Arthur Hvidtfeldt ◽  
Gianluca Severi ◽  
Zorana Jovanovic Andersen ◽  
Richard Atkinson ◽  
Mariska Bauwelinck ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Air Pollution ◽  
Ambient Air ◽  
Pooled Analysis ◽  
Ambient Air Pollution ◽  
Low Level ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals Air Pollution Exposure and Cognitive Function in Taiwanese Older Adults: A Repeated Measurement Study

2019 ◽  
Vol 16 (16) ◽  
pp. 2976 ◽  
Author(s):  
Yuan-Ting C. Lo ◽  
Ya-Chi Lu ◽  
Yu-Hung Chang ◽  
Senyeong Kao ◽  
Han-Bin Huang
Keyword(s):  
Older Adults ◽  
Air Pollution ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Ambient Air ◽  
Community Dwelling ◽  
Ambient Air Pollution ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Studies related to air pollution exposure and neurocognitive disorders, specifically cognitive impairment, among older adults are limited. We investigated the association between short-term and long-term exposure to ambient air pollution (i.e., particulate matter with an aerodynamic diameter of <10 μm and ozone) and the effects of their interaction on cognitive function in a community-dwelling, free-living elderly population. Study participants were in a multiple-wave representative sample, namely the Taiwan Longitudinal Study on Aging (n = 2241). In four surveys between 1996 and 2007, their cognitive function was assessed using the Short Portable Mental Status Questionnaire (SPMSQ). We estimated air pollution from 1993 to 2007, including daily concentrations of PM10 and O3 from air quality monitoring stations, based on the administrative zone of each participant’s residence. Generalized linear mixed models were used to examine these associations after adjusting for covariates. We found that long-term exposure to PM10 and O3 was significantly associated with cognitive impairment (OR = 1.094, 95% CI: 1.020, 1.174 for PM10; OR = 1.878, 95% CI: 1.363, 2.560 for O3). The joint effect of exposure to PM10 and O3 was associated with cognitive impairment (p < 0.001). Co-exposure to ambient PM10 and O3 may deteriorate cognitive function in older adults.

scholarly journals Long-term Air Pollution Exposure, Genome-wide DNA Methylation and Lung Function in the LifeLines Cohort Study

2018 ◽  
Vol 126 (2) ◽  
pp. 027004 ◽  
Author(s):  
Ana Julia de F.C. Lichtenfels ◽  
Diana A. van der Plaat ◽  
Kim de Jong ◽  
Cleo C. van Diemen ◽  
Dirkje S. Postma ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Air Pollution ◽  
Cohort Study ◽  
Lung Function ◽  
Genome Wide ◽  
Air Pollution Exposure ◽  
Pollution Exposure

The Association between Long-term Exposure to Ambient Air Pollution and Bone Strength in China

2021 ◽  
Author(s):  
Jialong Wu ◽  
Bing Guo ◽  
Han Guan ◽  
Fei Mi ◽  
Jingru Xu ◽  
...  
Keyword(s):  
Air Pollution ◽  
Bone Strength ◽  
Quantitative Ultrasound ◽  
Linear Models ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Middle Income ◽  
Air Pollution Exposure ◽  
Pollution Exposure

Abstract Context Evidence regarding the association of long-term exposure to air pollution on bone strength or osteoporosis is rare, especially in high polluted low- and middle-income countries. Little is known about whether the association between air pollution and bone strength changes at different bone strength distributions. Objective Using the baseline data from the China Multi-Ethnic Cohort, we investigated the association between long-term air pollution exposure and bone strength. Methods We used multiple linear models to estimate the association between air pollution and bone strength. And we conducted quantile regression models to investigate the variation of this association in the distribution of bone strength. The 3-year concentrations of PM1, PM2.5, PM10, and NO2 for each participant were assessed using spatial statistical models. Bone strength was expressed by the calcaneus quantitative ultrasound index (QUI) measured by quantitative ultrasound, with higher QUI values indicating greater bone strength. Result A total of 66,598 participants were included. Our analysis shows that every 10 μg/m 3 increase in 3-year average PM1, PM2.5, PM10, and NO2 was associated with -5.38 units (95% CI: -6.17, -4.60), -1.89 units (95% CI: -2.33, -1.44), -0.77 units (95% CI: -1.08, -0.47), and -2.02 units (95% CI: -2.32, -1.71) changes in the QUI, respectively. In addition, populations with higher bone strength may more susceptible to air pollution. Conclusions Long-term exposure to PM1, PM2.5, PM10, and NO2 was significantly associated with decreased bone strength in southwestern China adults. Air pollution exposure has a more substantial adverse effect on bones among populations with higher bone strength.

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