scholarly journals Global stability analysis for a generalized delayed SIR model with vaccination and treatment

2019 ◽  
Vol 2019 (1) ◽  
Author(s):  
A. Elazzouzi ◽  
A. Lamrani Alaoui ◽  
M. Tilioua ◽  
A. Tridane
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Distributed Delay ◽  
Vaccination Strategy ◽  
Asymptotically Stable ◽  
Sir Epidemic Model ◽  
Globally Asymptotically Stable ◽  
Susceptible Population ◽  
Sir Epidemic ◽  
The Basic Reproduction Number

AbstractIn this work, we investigate the stability of an SIR epidemic model with a generalized nonlinear incidence rate and distributed delay. The model also includes vaccination term and general treatment function, which are the two principal control measurements to reduce the disease burden. Using the Lyapunov functions, we show that the disease-free equilibrium state is globally asymptotically stable if $\mathcal{R}_{0} \leq 1 $R0≤1, where $\mathcal{R}_{0} $R0 is the basic reproduction number. On the other hand, the disease-endemic equilibrium is globally asymptotically stable when $\mathcal{R}_{0} > 1 $R0>1. For a specific type of treatment and incidence functions, our analysis shows the success of the vaccination strategy, as well as the treatment depends on the initial size of the susceptible population. Moreover, we discuss, numerically, the behavior of the basic reproduction number with respect to vaccination and treatment parameters.

scholarly journals Transmission Dynamics of a Two-City SIR Epidemic Model with Transport-Related Infections

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Yao Chen ◽  
Mei Yan ◽  
Zhongyi Xiang
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Sufficient Conditions ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Sir Epidemic Model ◽  
Globally Asymptotically Stable ◽  
Sir Epidemic ◽  
The Basic Reproduction Number

A two-city SIR epidemic model with transport-related infections is proposed. Some good analytical results are given for this model. If the basic reproduction numberℜ0γ≤1, there exists a disease-free equilibrium which is globally asymptotically stable. There exists an endemic equilibrium which is locally asymptotically stable if the basic reproduction numberℜ0γ>1. We also show the permanence of this SIR model. In addition, sufficient conditions are established for global asymptotic stability of the endemic equilibrium.

scholarly journals Stability Analysis of a Delayed SIR Epidemic Model with Stage Structure and Nonlinear Incidence

2009 ◽  
Vol 2009 ◽  
pp. 1-17 ◽  
Author(s):  
Xiaohong Tian ◽  
Rui Xu
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Sufficient Conditions ◽  
Stage Structure ◽  
Sir Epidemic Model ◽  
Globally Asymptotically Stable ◽  
Sir Epidemic ◽  
The Stability ◽  
The Basic Reproduction Number

We investigate the stability of an SIR epidemic model with stage structure and time delay. By analyzing the eigenvalues of the corresponding characteristic equation, the local stability of each feasible equilibrium of the model is established. By using comparison arguments, it is proved when the basic reproduction number is less than unity, the disease free equilibrium is globally asymptotically stable. When the basic reproduction number is greater than unity, sufficient conditions are derived for the global stability of an endemic equilibrium of the model. Numerical simulations are carried out to illustrate the theoretical results.

Dynamics of a delayed epidemic model with varying immunity period and nonlinear transmission

2015 ◽  
Vol 08 (02) ◽  
pp. 1550027 ◽  
Author(s):  
Aadil Lahrouz
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Sufficient Conditions ◽  
Distributed Delay ◽  
Incidence Rates ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Nonlinear Incidence ◽  
The Basic Reproduction Number

An epidemic model with a class of nonlinear incidence rates and distributed delay is analyzed. The nonlinear incidence is used to describe the saturated or the psychological effect of certain serious epidemics on the community when the number of infectives is getting larger. The distributed delay is derived to describe the dynamics of infectious diseases with varying immunity. Lyapunov functionals are used to show that the disease-free equilibrium state is globally asymptotically stable when the basic reproduction number is less than or equal to one. Moreover, it is shown that the disease is permanent if the basic reproduction number is greater than one. Furthermore, the sufficient conditions under which the endemic equilibrium is locally and globally asymptotically stable are obtained.

scholarly journals Partial Differential Equations of an Epidemic Model with Spatial Diffusion

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
El Mehdi Lotfi ◽  
Mehdi Maziane ◽  
Khalid Hattaf ◽  
Noura Yousfi
Keyword(s):  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Reaction Diffusion ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Sir Epidemic Model ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

The aim of this paper is to study the dynamics of a reaction-diffusion SIR epidemic model with specific nonlinear incidence rate. The global existence, positivity, and boundedness of solutions for a reaction-diffusion system with homogeneous Neumann boundary conditions are proved. The local stability of the disease-free equilibrium and endemic equilibrium is obtained via characteristic equations. By means of Lyapunov functional, the global stability of both equilibria is investigated. More precisely, our results show that the disease-free equilibrium is globally asymptotically stable if the basic reproduction number is less than or equal to unity, which leads to the eradication of disease from population. When the basic reproduction number is greater than unity, then disease-free equilibrium becomes unstable and the endemic equilibrium is globally asymptotically stable; in this case the disease persists in the population. Numerical simulations are presented to illustrate our theoretical results.

scholarly journals Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies

Mathematics ◽  
2018 ◽  
Vol 6 (12) ◽  
pp. 328 ◽  
Author(s):  
Yanli Ma ◽  
Jia-Bao Liu ◽  
Haixia Li
Keyword(s):  
Lyapunov Function ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number R 0 , which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when R 0 < 1 , and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when R 0 > 1 . Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when R 0 > 1 . Finally, some numerical simulations are presented to illustrate the analysis results.

Global dynamics for a live-virus-blood model with distributed time delay

2017 ◽  
Vol 10 (05) ◽  
pp. 1750067 ◽  
Author(s):  
Ding-Yu Zou ◽  
Shi-Fei Wang ◽  
Xue-Zhi Li
Keyword(s):  
Steady State ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Live Virus ◽  
Number Formula ◽  
Distributed Time Delay ◽  
The Basic Reproduction Number

In this paper, the global properties of a mathematical modeling of hepatitis C virus (HCV) with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number [Formula: see text] is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number [Formula: see text] is larger than unity, then the infected steady state is globally asymptotically stable.

scholarly journals On the Global Dynamics of a Vector-Borne Disease Model with Age of Vaccination

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Stanislas Ouaro ◽  
Ali Traoré
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Mass Action ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Vector Borne Disease ◽  
Special Cases ◽  
Vector Borne ◽  
The Basic Reproduction Number

We study a vector-borne disease with age of vaccination. A nonlinear incidence rate including mass action and saturating incidence as special cases is considered. The global dynamics of the equilibria are investigated and we show that if the basic reproduction number is less than 1, then the disease-free equilibrium is globally asymptotically stable; that is, the disease dies out, while if the basic reproduction number is larger than 1, then the endemic equilibrium is globally asymptotically stable, which means that the disease persists in the population. Using the basic reproduction number, we derive a vaccination coverage rate that is required for disease control and elimination.

scholarly journals Dynamics Analysis of a Viral Infection Model with a General Standard Incidence Rate

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Yu Ji ◽  
Muxuan Zheng
Keyword(s):  
Viral Infection ◽  
Incidence Rate ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Infection Model ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Reproduction Numbers ◽  
The Basic Reproduction Number ◽  
General Standard

The basic viral infection models, proposed by Nowak et al. and Perelson et al., respectively, have been widely used to describe viral infection such as HBV and HIV infection. However, the basic reproduction numbers of the two models are proportional to the number of total cells of the host's organ prior to the infection, which seems not to be reasonable. In this paper, we formulate an amended model with a general standard incidence rate. The basic reproduction number of the amended model is independent of total cells of the host’s organ. When the basic reproduction numberR0<1, the infection-free equilibrium is globally asymptotically stable and the virus is cleared. Moreover, ifR0>1, then the endemic equilibrium is globally asymptotically stable and the virus persists in the host.

An age-structured epidemic model with waning immunity and general nonlinear incidence rate

2018 ◽  
Vol 11 (05) ◽  
pp. 1850069 ◽  
Author(s):  
Xia Wang ◽  
Ying Zhang ◽  
Xinyu Song
Keyword(s):  
Steady State ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Threshold Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Waning Immunity ◽  
Age Structured ◽  
The Basic Reproduction Number

In this paper, a susceptible-vaccinated-exposed-infectious-recovered epidemic model with waning immunity and continuous age structures in vaccinated, exposed and infectious classes has been formulated. By using the Fluctuation lemma and the approach of Lyapunov functionals, we establish a threshold dynamics completely determined by the basic reproduction number. When the basic reproduction number is less than one, the disease-free steady state is globally asymptotically stable, and otherwise the endemic steady state is globally asymptotically stable.

The impact of media coverage with a piecewise transmission rate in the spread of diseases

2016 ◽  
Vol 10 (01) ◽  
pp. 1750003
Author(s):  
Maoxing Liu ◽  
Lixia Zuo
Keyword(s):  
Basic Reproduction Number ◽  
Media Coverage ◽  
Reproduction Number ◽  
Transmission Rate ◽  
Three Dimensional ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Contact Transmission ◽  
The Impact ◽  
The Basic Reproduction Number

A three-dimensional compartmental model with media coverage is proposed to describe the real characteristics of its impact in the spread of infectious diseases in a given region. A piecewise continuous transmission rate is introduced to describe that media coverage exhibits its effect only when the number of the infected exceeds a certain critical level. Further, it is assumed that the impact of media coverage on the contact transmission is described by an exponential decreasing factor. Stability analysis of the model shows that the disease-free equilibrium is globally asymptotically stable if the basic reproduction number is less than unity. On the other hand, when the basic reproduction number is greater than unity and media coverage impact is sufficiently small, a unique endemic equilibrium exists, which is globally asymptotically stable.

Sign in / Sign up

Export Citation Format

Share Document