scholarly journals Changes in newly notified cases and control of tuberculosis in China: time-series analysis of surveillance data

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Ye-Sheng Wang ◽  
Wen-Long Zhu ◽  
Tao Li ◽  
Wei Chen ◽  
Wei-Bing Wang

Abstract Background China has made progress in tuberculosis control, but this disease remains a burden in many regions of China. We performed time-series analysis to examine changes in the rates of newly notified and newly smear-positive cases of tuberculosis in different regions of China from 1997 to 2018 and assessed the effect of the current control program. Methods National and provincial notification data on tuberculosis from 1997 to 2018, which covers 31 provinces in the mainland of China, were extracted from the Chinese public health science data center. The annual percentage changes in newly notified and smear-positive cases were analyzed using a joinpoint regression method. Results There were 18 646 672 newly notified tuberculosis cases from 1997 to 2018, with the greatest number in 2005. A total of 6 605 414 of these cases (35.42%) were smear-positive cases. The number of newly notified cases in China overall decreased (96.88–59.27 cases per 100 000) significantly during the most recent years. The decline during this period ranged from −3.9% (95% CI −5.7 to −2.9) in the western region to −4.3% (95% CI −4.8 to −3.7) in the eastern region. Most provinces had significant declines in newly notified and smear-positive cases, whereas the decline of newly smear-positive cases in Xinjiang was about half of that observed during the same period in China overall (−4.1% vs −9.9%). In addition to disparities in annual percentage changes, the rate of newly notified cases was higher in the western region than in the eastern and central regions. Conclusions The burden of tuberculosis has been on declining throughout China during recent years, but tuberculosis in western China continues to be a public health emergency that needs to be urgently addressed. Effective prevention and control strategies are needed for regions with high disease burdens and those with increasing or unchanging numbers of newly notified and smear-positive cases of tuberculosis.

2020 ◽  
Author(s):  
Yesheng Wang ◽  
Wenlong Zhu ◽  
Tao Li ◽  
Wei Chen ◽  
Wei-bing Wang

Abstract Background: China has made progress in tuberculosis control, but this disease remains a burden in many regions of China. We performed time-series analysis to examine changes in the rates of newly notified and newly smear-positive cases of tuberculosis in different regions of China from 1997 to 2018 and assessed the effect of the current control program. Methods: National and provincial notification data on tuberculosis from 1997 to 2018, which covers 31 provinces in mainland China, were extracted from the Chinese public health science data center. The annual percentage changes in newly notified and smear-positive cases were analyzed using a joinpoint regression method. Results: There were 18,646,672 newly notified tuberculosis cases from 1997 to 2018, with the greatest number in 2005. A total of 6,605,414 of these cases (35.42%) were smear-positive cases. Most provinces had significant declines in newly notified and smear-positive cases during the most recent years. The declines in newly notified cases were faster in the eastern and central provinces than in the western provinces. Conclusions: The burden of tuberculosis has been declining throughout China during recent years, but tuberculosis in western China continues to be a public health emergency that needs to be urgently addressed. Effective prevention and control strategies are needed for regions with high disease burdens and those with increasing or unchanging numbers of newly notified and smear-positive cases of tuberculosis.


2020 ◽  
Author(s):  
Yesheng Wang ◽  
Wenlong Zhu ◽  
Tao Li ◽  
Wei Chen ◽  
Wei-bing Wang

Abstract Background China has made progress in tuberculosis control, but this disease remains a burden in many regions of China. We performed time-series analysis to examine changes in the rates of newly notified and newly smear-positive cases of tuberculosis in different regions of China from 1997 to 2017 and assessed the effect of the current control program. Methods National and provincial notification data on tuberculosis from 1997 to 2017, which covers 31 provinces in mainland China, were extracted from the Chinese public health science data center. The annual percentage changes in newly notified and smear-positive cases were analyzed using a joinpoint regression method. Results There were 17,823,330 newly notified tuberculosis cases from 1997 to 2017, with the greatest number in 2005. A total of 6,378,785 of these cases (35.79%) were smear-positive cases. Most provinces had significant declines in newly notified and smear-positive cases during the most recent years. The declines in newly notified cases were faster in the eastern and central provinces than in the western provinces. Conclusions The burden of tuberculosis has been declining throughout China during recent years, but tuberculosis in western China continues to be a public health emergency that needs to be urgently addressed. Effective prevention and control strategies are needed for regions with high disease burdens and those with increasing or unchanging numbers of newly notified and smear-positive cases of tuberculosis.


Author(s):  
Cristiano Ialongo ◽  
Antonella Farina ◽  
Raffaella Labriola ◽  
Antonio Angeloni ◽  
Emanuela Anastasi

We read with great interest the paper by Gaudio and colleagues on vitamin D and on the state of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the time of admission [...]


1971 ◽  
Vol 134 (3) ◽  
pp. 450 ◽  
Author(s):  
M. G. Kendall ◽  
G. E. P. Box ◽  
G. M. Jenkins

Econometrica ◽  
1972 ◽  
Vol 40 (5) ◽  
pp. 970 ◽  
Author(s):  
J. N. K. Rao ◽  
G. E. P. Box ◽  
G. M. Jenkins

CJEM ◽  
2018 ◽  
Vol 20 (S1) ◽  
pp. S39-S39
Author(s):  
J. Moe ◽  
C. Camargo ◽  
S. E. Jelinski ◽  
S. Erdelyi ◽  
J. Brubacher ◽  
...  

Introduction: Substance and opioid misuse are growing public health concerns in Canada. Substance use disorders affect 21.6% of Canadians and accounted for $267 million in healthcare costs in 2011. Opioid misuse is a current public health crisis. The extent of the rise in substance and opioid misuse-related Emergency Department (ED) visits in Canada and the demographic groups in which the rise is concentrated have not been elaborated. Alberta has one of the most complete provincial ED visit records and provides an important understanding of national trends. The objective of this study was to evaluate trends in substance and opioid misuse-related ED visits in Alberta from 2010/11 to 2014/5 within demographic cross-sections of the population using administrative ED visit data from the National Ambulatory Care Reporting System (NACRS). Methods: All visits made by adult patients (18 years old) to any of more than 100 Albertan EDs for a substance misuse-related presentation between 2010/11 and 2014/15 were analyzed. Visits were classified as being related to substance or opioid misuse if the primary and/or secondary visit diagnoses were among an a priori determined group of ICD-10 codes. Annual substance misuse-related visits were compared as visits per 100,000 adult population in Alberta to standardize for population growth. Linear regression was used to assess whether ED visits increased significantly over time. A cross-sectional time-series analysis was employed to examine trends within subgroups defined by sex and age categories (18-29, 30-39, 40-49, 50-59, and 60 years) over a 60-month period. Results: 149,719 substance misuse-related visits were made by 65,089 patients and 8768 opioid misuse-related visits were made by 5763 patients. From 2010/11 to 2014/15, substance misuse-related ED visits in Alberta increased by 38% from 811 to 1119 visits per 100,000 population. Opioid misuse-related ED visits increased significantly (64%) from 44 to 72 per 100,000 population. Conversely, total ED visits per 100,000 population did not increase significantly. Substance and opioid misuse-related visits rose more in non-rural than rural areas. Cross-sectional time-series analysis showed that the greatest increase in substance and opioid misuse-related ED visits occurred in males and in the 18-29 year age category, in which visit increases for opioid misuse appeared exponential. Conclusion: Substance and opioid misuse-related ED visits increased significantly from 2010/11 to 2014/15 in Alberta, with the most dramatic increases occurring in young patients and males. These findings have important implications for targeting urgent preventative public health interventions to stem the rise of this epidemic.


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