scholarly journals TOX as a potential target for immunotherapy in lymphocytic malignancies

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Chaofeng Liang ◽  
Shuxin Huang ◽  
Yujie Zhao ◽  
Shaohua Chen ◽  
Yangqiu Li
Keyword(s):  
T Cell ◽  
Potential Role ◽  
Hematological Malignancies ◽  
High Mobility ◽  
High Mobility Group ◽  
Biological Functions ◽  
Hmg Box ◽  
Cell Exhaustion ◽  
Potential Target

AbstractTOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing studies have shown that TOX is involved in maintaining tumors and promoting T cell exhaustion. In this review, we summarized the biological functions of TOX and its contribution as related to lymphocytic malignancies. We also discussed the potential role of TOX as an immune biomarker and target in immunotherapy for hematological malignancies.

Role of Receptors for Advanced Glycation End Products and High-Mobility Group Box 1 in the Outcome of Human T Cell Lymphotropic Type 1 Infection

2019 ◽  
Vol 32 (2) ◽  
pp. 89-94 ◽  
Author(s):  
Nafise Yaghouti ◽  
Reza Boostani ◽  
Asadollah Mohamamdi ◽  
Zohreh Poursina ◽  
Seyed Abdolrahim Rezaee ◽  
...  
Keyword(s):  
T Cell ◽  
Advanced Glycation End Products ◽  
High Mobility ◽  
High Mobility Group ◽  
Advanced Glycation ◽  
Human T Cell ◽  
Glycation End Products ◽  
End Products

Role, function and regulation of the thymocyte selection-associated high mobility group box protein in CD8+ T cell exhaustion

2021 ◽  
Vol 229 ◽  
pp. 1-7
Author(s):  
Yanmin Cheng ◽  
Zhaozhao Shao ◽  
Li Chen ◽  
Qiaoyu Zheng ◽  
Qiqi Zhang ◽  
...  
Keyword(s):  
T Cell ◽  
High Mobility ◽  
Cd8 T Cell ◽  
High Mobility Group ◽  
T Cell Exhaustion ◽  
Cell Exhaustion ◽  
Role Function

scholarly journals The Role of High-Mobility Group I(Y) Proteins in Expression of IL-2 and T Cell Proliferation

2000 ◽  
Vol 164 (6) ◽  
pp. 3157-3168 ◽  
Author(s):  
S. Roy Himes ◽  
Raymond Reeves ◽  
Joanne Attema ◽  
Mark Nissen ◽  
Ying Li ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
T Cell ◽  
High Mobility ◽  
High Mobility Group ◽  
T Cell Proliferation ◽  
Group I

A potential role of high mobility group box-1 (HGMB1) in inflammatory vascular remodelling

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
H Xu ◽  
D Zabini ◽  
A Olschewski ◽  
G Kwapiszewska ◽  
LM Marsh
Keyword(s):  
Potential Role ◽  
High Mobility ◽  
High Mobility Group ◽  
Vascular Remodelling

scholarly journals Potential role of high-mobility group box 1 protein in the pathogenesis of influenza H5N1 virus infection

2014 ◽  
Vol 58 (01) ◽  
pp. 69-75 ◽  
Author(s):  
X. Q. HOU ◽  
J. L. QIN ◽  
X. X. ZHENG ◽  
L. WANG ◽  
S. T. YANG ◽  
...  
Keyword(s):  
Virus Infection ◽  
H5n1 Virus ◽  
Potential Role ◽  
High Mobility ◽  
High Mobility Group ◽  
Influenza H5n1

scholarly journals Potential Role of High Mobility Group Box 1 in Viral Infectious Diseases

2006 ◽  
Vol 19 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Haichao Wang ◽  
Mary F. Ward ◽  
Xue-Gong Fan ◽  
Andrew E. Sama ◽  
Wei Li
Keyword(s):  
Infectious Diseases ◽  
Potential Role ◽  
High Mobility ◽  
High Mobility Group

scholarly journals Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease

2008 ◽  
Vol 178 (8) ◽  
pp. 822-831 ◽  
Author(s):  
Steven M. Rowe ◽  
Patricia L. Jackson ◽  
Gang Liu ◽  
Mathew Hardison ◽  
Alessandra Livraghi ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Potential Role ◽  
High Mobility ◽  
Airway Disease ◽  
High Mobility Group ◽  
Cystic Fibrosis Airway

scholarly journals Sterile Inflammatory Role of High Mobility Group Box 1 Protein: Biological Functions and Involvement in Disease

2018 ◽  
Vol 55 (4) ◽  
pp. 244-254
Author(s):  
Sera Gonelevue ◽  
Abhirup Bandyopadhyay ◽  
Saumya Bhagat ◽  
Md Iqbal Alam ◽  
Gausal A. Khan
Keyword(s):  
High Mobility ◽  
High Mobility Group ◽  
Biological Functions
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