scholarly journals Epidemiological trends of urinary tract infections, urolithiasis and benign prostatic hyperplasia in 203 countries and territories from 1990 to 2019

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Cong Zhu ◽  
Dan-Qi Wang ◽  
Hao Zi ◽  
Qiao Huang ◽  
Jia-Min Gu ◽  
...  

Abstract Background Urinary tract infections (UTI), urolithiasis, and benign prostatic hyperplasia (BPH) are three of the most common nonmalignant conditions in urology. However, there is still a lack of comprehensive and updated epidemiological data. This study aimed to investigate the disease burden of UTI, urolithiasis, and BPH in 203 countries and territories from 1990 to 2019. Methods Data were extracted from the Global Burden of Disease 2019, including incident cases, deaths, disability-adjusted life-years (DALYs) and corresponding age-standardized rate (ASR) from 1990 to 2019. Estimated annual percentage changes (EAPC) were calculated to evaluate the trends of ASR. The associations between disease burden and social development degrees were analyzed using a sociodemographic index (SDI). Results Compared with 1990, the incident cases of UTI, urolithiasis, and BPH increased by 60.40%, 48.57%, and 105.70% in 2019, respectively. The age-standardized incidence rate (ASIR) of UTI increased (EAPC = 0.08), while urolithiasis (EAPC = − 0.83) and BPH (EAPC = − 0.03) decreased from 1990 to 2019. In 2019, the age-standardized mortality rate (ASMR) of UTI and urolithiasis were 3.13/100,000 and 0.17/100,000, respectively. BPH had the largest increase (110.56%) in DALYs in the past three decades, followed by UTI (68.89%) and urolithiasis (16.95%). The burden of UTI was mainly concentrated in South Asia and Tropical Latin America, while the burden of urolithiasis and BPH was recorded in Asia and Eastern Europe. Moreover, the ASIR and SDI of urolithiasis in high-SDI regions from 1990 to 2019 were negatively correlated, while the opposite trend was seen in low-SDI regions. In 2019, the ASIR of UTI in females was 3.59 times that of males, while the ASIR of urolithiasis in males was 1.96 times higher than that in females. The incidence was highest in the 30–34, 55–59, and 65–69 age groups among the UTI, urolithiasis, and BPH groups, respectively. Conclusion Over the past three decades, the disease burden has increased for UTI but decreased for urolithiasis and BPH. The allocation of medical resources should be based more on the epidemiological characteristics and geographical distribution of diseases.

2021 ◽  
Author(s):  
Cong Zhu ◽  
Dan-Qi Wang ◽  
Hao Zi ◽  
Qiao Huang ◽  
Jia-Min Gu ◽  
...  

Abstract BackgroundTo investigate the disease burden of urinary tract infections (UTI), urolithiasis, and benign prostatic hyperplasia (BPH) in 204 countries and territories from 1990 to 2019.MethodsData were extracted from the Global Burden of Disease 2019, including incident cases, deaths, disability-adjusted life-years (DALYs) and corresponding age-standardized rate (ASR) from 1990 to 2019. Estimated annual percentage changes (EAPC) were calculated to evaluate the trends of ASR. The associations between disease burden and social development degrees were analyzed by socio-demographic index (SDI).ResultsCompared with 1990, the incident cases of UTI, urolithiasis, and BPH increased by 60.40%, 48.57%, and 105.70% in 2019, respectively. The age-standardized incidence rate (ASIR) of UTI increased (EAPC = 0.08), while urolithiasis (EAPC = -0.83) and BPH (EAPC = -0.03) decreased from 1990 to 2019. In 2019, the age-standardized mortality rate (ASMR) of UTI and urolithiasis was 3.13/100,000 and 0.17/100,000, respectively. BPH had the largest increase (110.56%) in DALYs in past three decades, followed by UTI (68.89%) and urolithiasis (16.95%). The burden of UTI mainly concentrated in South Asia and Tropical Latin America while the burden of urolithiasis and BPH was recorded in Asia and Eastern Europe. Moreover, the ASIR and SDI of urolithiasis in high SDI regions from 1990 to 2019 were negatively correlated, while the opposite trend was in low SDI regions. In 2019, the ASIR of UTI in female was 3.59 times that of male, while the ASIR of urolithiasis in male was 1.96 times higher than female. The incidence was highest in 30-34, 55-59, and 65-69 age group among UTI, urolithiasis, and BPH, respectively. ConclusionsOver the past three decades, the disease burden remains increased in UTI, while decreased in urolithiasis and BPH. The allocation of medical resources should be more based on the epidemiological characteristics and geographical distribution of diseases.


2021 ◽  
Author(s):  
Cong Zhu ◽  
Qiao Huang ◽  
Li-Sha Luo ◽  
Tong Deng ◽  
Jia-Min Gu ◽  
...  

Abstract BackgroundUrinary tract infections (UTIs) are some of the most common infections worldwide and consume a lot of medical resources every year. However, there were a lack of available data on its incidence and disease burden. We armed to investigate incidence, mortality, and disability adjusted life-years (DALYs) of urinary tract infections (UTIs) from 1990 to 2017.MethodsWe extracted data from the Global Burden of Disease Study 2017, then calculated estimated annual percentage changes (EAPC) of age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), and age-standardized DALYs rate at global, national, regional, and socio-demographic index (SDI) level.ResultsFrom 1990 to 2017, the globally incident cases (+52.09%), death cases (+140.10%), and DALYs (+69.65%) of UTIs all increased. The ASIR, ASDR, and age-standardized DALYs rate showed upward trends with the EAPC of +0.10 (95%CI: 0.07 to 0.12), +0.72 (95%CI: 0.65-0.78), and +0.06 (95%CI: -0.05 to 0.16), respectively. The ASIR decreased only in the high-middle SDI quantile (-0.26, 95%CI: -0.3 to -0.23). United Arab Emirates had the largest increase of DALYs (+835.04%), but Bulgaria had the largest decrease (-80.74%). EAPC for incidence and mortality were below 0 mainly in Europe and East Asia. In 2017, the incident cases (+3.44 times), the deaths (+1.31 times), and DALYs (+1.21 times) were all higher in females than males. The incident cases were mainly concentrated in 15-49 years old; DALYs and mortality were higher in over 80 age groups.ConclusionsGlobally, the burden of UTIs increased from 1990 to 2017, especially in females; however, distinct varies were observed in different regions and countries. The infants and elders are easier to die when they suffer from UTIs.


2013 ◽  
Vol 33 (4) ◽  
pp. 177 ◽  
Author(s):  
Christine Bradway ◽  
M. Biran Bixby ◽  
Karen B. Hirschman ◽  
Kathleen McCauley ◽  
Mary D. Naylor

2016 ◽  
Vol 64 (4) ◽  
pp. 938.2-939
Author(s):  
A Al-khazraji ◽  
H Alkhawam ◽  
B Garrido

Case presentationThis is a 25 years old Pilipino male with no past medical history who presented with fever, rigors, fatigue and night sweats for 3 days. His symptoms progressively getting worse which made him seek medical attention. Patient travelled to Philippines five months ago which he stayed for a month.Upon presentation, patient was febrile with Temp 104 F and tachycardic 139 BPM, BP113/76. He appeared to be diaphoretic and tachypnic on physical exam. Abdomen was soft and non-tender, no hepatomegaly or splenomegaly on palpation.Pertinent laboratory findings included leukocytosis of 14,000 and bandemia 12, lactate of 3.6, Liver function tests – AST 62/ALT 61/ ALK 52 GGT 48 LDH 347 Total bilirubin 2.5 and direct Bilirubin 1.6 – Hepatitis serology revealed immunity against Hepatitis B (HBV). Coagulation panel and renal function were normal. Abdominal imaging revealed diffuse hepatic changes suggestive of cirrhosis and complex avascular slightly lobulated hypoechoic mass with mild posterior enhancement measuring 7.2×6.8 cm noted in the anteromedial portion of posterior segment of the right lobe (figure 1A and B).Further tests including HIV testing, urine analysis, blood and urine cultures, Echinococcosis and Amoebic serology were none revealing. Empirical broad spectrum antibiotics with 3rd generation cephalosporin and metronidazole for possible amoebic verus pyogenic liver abscess.After 3–4 days from admission date, he developed persistent rigors, tachycardia, and appeared to have respiratory distress which required an urgent intubation for acute respiratory failure and transferred to ICU. Urgent drainage attempted for pyogenic liver abscess. Abscess fluid culture was positive for Klebsiella pneumonia.Patient received an intravenous ceftriaxone 2 gm daily with continuous Jackson-Pratt liver drain suction for 3–4 weeks which was curative with resolution and decrease in the size of liver abscess on repeat imaging (figure 1c).DiscussionKlebsiella pneumoniae, a member of the Enterobacteriaceae family, is a pathogen with worldwide distribution. Most community-acquired Klebsilla pneumoniae infections cause pneumonia or urinary tract infections. Invasive liver abscess syndrome is very rare in western countries. For the past 2 decades, a distinct clinical syndrome has been emerging in Southeast Asia that is characterized by bacteremia, liver abscesses, and metastatic infections. In the past decade, few patients were diagnosed as having a liver abscess caused by K pneumoniae in two case series in the USA.Most community-acquired Klebsilla pneumoniae infections cause pneumonia or urinary tract infections. Invasive liver abscess syndrome is very rare in western countries. Clinicians should be aware about invasive klebsiella pneumonia liver abscess especially in patients with Asian background presented with liver abscess failed the treatment with antibiotics. Treatment of invasive klebsiella pneumonia liver abscess requires dual approach medical and surgical as we approached our patient which he subsequently improved after CT-guided liver abscess drainage and four weeks of antibiotics therapy.Abstract ID: 29 Figure 1


2019 ◽  
Vol 68 (5) ◽  
pp. 115-122
Author(s):  
Alexandra M. Khudovekova ◽  
Elena V. Mozgovaya

A urinary tract infection (UTI) during pregnancy remains one of the most important problems of obstetrics, urology, and nephrology. Pregnancy as physiological process contributes to UTI. This is caused by urinary clinical signs changing during pregnancy, approaches to diagnosis and treatment, as well as to the risk of developing urological, obstetric and neonatal complications. This article analyzes contemporary literature over the past 10 years.


2014 ◽  
Vol 28 (5) ◽  
pp. 621-626 ◽  
Author(s):  
Shengsheng Yu ◽  
Alex Z. Fu ◽  
Ying Qiu ◽  
Samuel S. Engel ◽  
Ravi Shankar ◽  
...  

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Navin Shrestha ◽  
Huanchun Hu ◽  
Le Zhou ◽  
Bo Wang

Benign prostatic hyperplasia, which can be abbreviated as prostatic hyperplasia, is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China. The incidence of benign prostatic hyperplasia is increasing year by year. Patients with benign prostatic hyperplasia are prone to have bladder outlet obstruction, which in turn leads to an increase in residual urine volume in the bladder and impurities in the urine, such as upper urinary calculi that enter the bladder, urine crystals, various exfoliated cells, etc. If these substances stay in the bladder for a long time, stones in the bladder will be generated. Benign prostatic hyperplasia with bladder stones can severely obstruct the urinary tract, causing clinical symptoms such as urinary tract infections, urinary urgency, frequent urination, and dysuria. These symptoms seriously affects the physical and mental health of patients, leading to low levels of normal work and quality of life. With the development of medical technology, surgical treatment is commonly used in clinical practice. Among them, transurethral prostatectomy is widely used in clinical treatment, and has achieved good results.


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