scholarly journals Complete atrio-ventricular block with coronary artery spasm due to direct laryngoscopy in a pediatric patient with laryngeal papillomatosis: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Katsuyuki Matsushita ◽  
Risa Arai ◽  
Tetsuzo Nakayama ◽  
Toshiaki Nakagaki ◽  
Tadashi Kandabashi ◽  
...  

Abstract Background Coronary artery spasm has rarely been reported in pediatric patients. Previous studies have reported comorbidities and risk factors for coronary artery spasms. We present the case of a complete atrio-ventricular (AV) block that occurred in the absence of other risk factors immediately after direct laryngoscopy. Case presentation A 2-year-old girl developed severe coronary artery spasm after direct laryngoscopy for elective laryngeal papillomatosis resection. Immediately after the initiation of laryngoscopy, complete AV block and ST elevation on lead II of the electrocardiogram were observed. These findings indicated that the complete AV block was caused by a right coronary artery spasm. Conclusion Coronary artery spasm resulting in lethal arrhythmia rarely occurs in healthy pediatric patients. To the best of our knowledge, this is the first pediatric case of a severe coronary artery spasm resulting in a complete AV block due to direct laryngoscopy in a healthy patient.

CHEST Journal ◽  
2021 ◽  
Vol 160 (4) ◽  
pp. A110
Author(s):  
Jasmine Sandhu ◽  
Andres Cordova Sanchez ◽  
Matthew Kovach ◽  
Markus Gutsche

1995 ◽  
Vol 25 (6) ◽  
pp. 1122
Author(s):  
Chang Gyu Park ◽  
Dong Kyu Jin ◽  
Do Sun Yim ◽  
Young Hoon Kim ◽  
Hong Seog Suh ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Victor Wakim ◽  
Elie Abi Khalil ◽  
Angelique K. Salloum ◽  
Georges Khazen ◽  
Michella Ghassibe-Sabbagh ◽  
...  

Abstract Background Coronary Artery Disease (CAD) is the narrowing or blockage of the coronary arteries. It is closely associated with numerous genetics and environmental factors that have been extensively evaluated in various populations. In recent studies, severe phenotypes have been strongly linked to genetic risk factors. Methods This study investigated the association of clinical, demographic, and genetic factors with severe coronary artery stenosis phenotypes in our population composed of 1734 individuals with severe coronary stenosis (≥ 50% in coronary vessels) and comparing them to 757 controls with no evidence of stenosis on angiography. We performed generalized linear model (GLM) genome-wide association studies to evaluate three stratification models and their associations to characteristics of the clinical disease. In model 1, patients were not stratified. In model 2, patients were stratified based on presence or absence of CAD family history (FxCAD). In model 3, patients were stratified by young age of CAD onset. Results Eight SNPs (single nucleotide polymorphism) were significantly associated with severe CAD phenotypes in the various models $$\left( {p < 5 \times 10^{ - 7} } \right)$$ p < 5 × 10 - 7 , four of these SNPs were associated with severe CAD and the four others were specifically significant for young CAD patients. While these SNPs were not previously reported for association with CAD, six of them are present in genes that have already been linked to coronary disease. Conclusion In conclusion, this study presents new genetic factors associated with severe stenosis and highlights different risk factors associated with a young age at diagnosis of CAD.


2015 ◽  
Vol 21 (2) ◽  
pp. 95-98
Author(s):  
Seung Hyun Hong ◽  
Kyung Ae Lee ◽  
Tae Sun Park ◽  
Hong Sun Baek ◽  
Heung Yong Jin ◽  
...  

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