scholarly journals ACUTE CORONARY SYNDROME AMONG YOUNG ADULTS WITH MODIFIABLE RISK FACTORS LINKED TO SEVERE CORONARY ARTERY DISEASE IN TRINIDAD & TOBAGO

2020 ◽  
Vol 75 (11) ◽  
pp. 3608
Author(s):  
Ravi Ramlal ◽  
Nicholas Taklalsingh ◽  
Ronan Ali ◽  
Risshi Rampersad ◽  
Ronald E. Henry ◽  
...  
Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 595
Author(s):  
Mircea Bajdechi ◽  
Cosmin Mihai ◽  
Alexandru Scafa-Udriste ◽  
Ali Cherry ◽  
Diana Zamfir ◽  
...  

The pathophysiology of accelerated atherosclerosis in people living with Human Immunofediciency virus (HIV) is complex. Coronary artery disease (CAD) has become an important cause of mortality in these patients. They often have atypical symptoms, leading to frequently missed diagnoses. We report a case of a 51-year-old male undergoing antiretroviral therapy who was admitted for acute coronary syndrome. He had severe coronary artery disease that involved difficult management.


2003 ◽  
Vol 42 (148) ◽  
Author(s):  
Man B KC ◽  
S Rajbhandari ◽  
D Sharma ◽  
R Malla ◽  
YR Limbu ◽  
...  

A total of 230 patients admitted in coronary care unit of Shahid Gangalal National Heart Centre in betweenNovember 2001 and October 2002 were studied. 157 (68.2%) were male, with mean age of 62.8±11.8 years.Majority of acute coronary syndrome (ACS) events were observed in males with advanced age (> 65 years).About 68% patients with ACS were smoker, the most common modifiable risk factor followed by hypertension,dyslipidaemia and diabetes. A strong trend towards development of coronary artery disease (CAD) wasfound in subjects with positive family history of CAD. Multiple risk factors (2 or more) were present in vastmajority of patients. Modifiable risk factors, with smoking at number one position are more common inacute coronary syndrome patients. Appropriate management of modifiable risk factors is advisable to reducethe incidence of coronary artery disease.Key Words: Coronary Artery Disease, Risk Factors.


2017 ◽  
Vol 69 (11) ◽  
pp. 254 ◽  
Author(s):  
Amar N. Patnaik ◽  
Pankajkumar A. Kasar ◽  
Raju V.R.C. Pusapati ◽  
K. Jagadishbabu ◽  
Naveenkrishna Kamana ◽  
...  

2020 ◽  
Author(s):  
GZK Niazi ◽  
F Adnan ◽  
MS Saleemi ◽  
A Akhtar ◽  
N Ahmed ◽  
...  

Background: Hypertension, dyslipidemia, and disturbed glucose metabolism associated with central obesity are often referred to as Metabolic Syndrome (MetS) and patients of MetS have a two- to three-fold increased risk for the development of cardiovascular diseases. Objective: Objectives were to determine the frequency of MetS in patients presenting with acute coronary syndromes and to compare the frequencies of severe coronary artery disease in patients with and without MetS. Methods: This descriptive cross-sectional study included 200 patients with acute coronary syndromes over a period of six months. Frequency of MetS was calculated. The frequencies of severe coronary artery disease were compared between patients having MetS and not having MetS using chi-square chart. Results: Total 200 patients with the mean age of 54.24 ± 9.41 years were included. 131 (65.5%) patients with acute coronary syndrome had MetS. Total 112 patients (56%) had severe coronary artery disease. 63.35% with MetS and 42.03% without MetS had severe coronary artery disease (p=0.003). Conclusion: The frequency of metabolic syndrome was high (65.5%) in patients with acute coronary syndromes and severe coronary artery disease was found to be associated with the presence of metabolic syndrome in these patients.


2020 ◽  
Author(s):  
Gul Zaman Khan Niazi ◽  
Syed Tahseen Shehzad ◽  
Ammar Akhtar ◽  
Muhammad Sohail Saleemi

ABSTRACT Background: Hypertension, dyslipidemia, and disturbed glucose metabolism associated with central obesity are often referred to as Metabolic Syndrome (MetS) and patients of MetS have a two- to three-fold increased risk for the development of cardiovascular diseases. Objective: Objectives were to determine the frequency of MetS in patients presenting with acute coronary syndromes and to compare the frequencies of severe coronary artery disease in patients with and without MetS. Methods: This descriptive cross-sectional study included 200 patients with acute coronary syndromes over a period of six months. Frequency of MetS was calculated. The frequencies of severe coronary artery disease were compared between patients having MetS and not having MetS using chi-square chart. Results: Total 200 patients with the mean age of 54.24 ± 9.41 years were included. 131 (65.5%) patients with acute coronary syndrome had MetS. Total 112 patients (56%) had severe coronary artery disease. 63.35% with MetS and 42.03% without MetS had severe coronary artery disease (p=0.003). Conclusion: The frequency of metabolic syndrome was high (65.5%) in patients with acute coronary syndromes and severe coronary artery disease was found to be associated with the presence of metabolic syndrome in these patients


2018 ◽  
Vol 33 (1) ◽  
pp. 10-15
Author(s):  
Mohsin Ahmed ◽  
Khandaker Abu Rubaiyat ◽  
Mohammed Abaye Deen Saleh ◽  
Abdul Wadud Chowdhury ◽  
CM Khudrate E Khuda ◽  
...  

Aims: Coronary artery disease is a devastating disease precisely because an otherwise healthy person in the prime of life may die or become disabled without warning. The objectives were to study the clinical profile, risk factors prevalence, angiographic distribution and severity of coronary artery stenosis in acute coronary syndrome (ACS) patients admitted in Cardiology Department of Dhaka Medical College Hospital, Dhaka.Materials and Methods: A total of 800 patients of ACS were analyzed for various risk factors, angiographic patterns and severity of coronary artery disease at DMCH, Dhaka, Bangladesh.Results: Mean age of presentation was 51.27±8.80 years. Majority were male 628 (78.5%) and rest were females (21.5%). Most patients had ST elevated myocardial infarction (STEMI) 509 (63.6%) followed by non-STEMI (NSTEMI) 207 (25.9%) and Unstable Angina (UA) 84 (10.5%). Risk factors: smoking was present in 388 (48.5%), hypertension in 289 (36.13%), diabetes in 235 (29.38%), dyslipidaemia in 169 (21.13%) and obesity in 356 (44.5%) patients. Singlevessel disease was present in 30.32% patients, Doublevessel disease was present in 23.23% patients and Triple vessel disease was present in 27.15% patients.Conclusion: STEMI was the most common presentation. ACS occurred earlier in comparison to Western population. Smoking was most prevalent risk factor. Diabetic patients had more multivessel disease.Bangladesh Heart Journal 2018; 33(1) : 10-15


Author(s):  
Negar Omidi ◽  
Saeed Sadeghian ◽  
Mojtaba Salarifar ◽  
Arash Jalali ◽  
Seyed Hesameddin Abbasi ◽  
...  

Background: Acute coronary syndrome (ACS) is one of the main causes of mortality worldwide. We sought to evaluate the correlation between the severity of coronary artery disease (CAD) and conventional coronary artery risk factors in a large cohort of patients with ACS. Methods: This study included all patients admitted to the coronary care unit with a diagnosis of ACS between 2003 and 2017. The patients were divided into 2 groups: 1) unstable angina and 2) myocardial infarction. The aims of this study were to evaluate the effects of the risk factors and extension of coronary artery stenosis in patients with ACS according to the Gensini score. Results: Of a total 40 319 patients who presented with ACS, 18 862 patients (mean age =60.4±11.14 y, male: 67.2%) underwent conventional coronary angiography and met our criteria to enter the final analysis. The median of the Gensini score was 50 (25–88) in the study population. The multivariable analysis showed that age, sex, diabetes mellitus, hypertension, dyslipidemia, family history, cigarette smoking, opium consumption, and myocardial infarction increased the risk of positive Gensini scores. All the aforementioned risk factors, except cigarette smoking and opium consumption, increased the severity of stenosis in those with positive Gensini scores. The strongest relationship was seen vis-à-vis myocardial infarction, sex, and diabetes mellitus. Conclusion: Our findings suggest that age, sex, diabetes mellitus, dyslipidemia, hypertension, family history, and myocardial infarction have significant effects on the severity of CAD. The obesity paradox in relation to CAD should be taken into consideration and needs further investigation in patients with ACS.


2014 ◽  
Vol 15 (2) ◽  
pp. 135-140
Author(s):  
NS Neki

Coronary artery disease (CAD) - which includes coronary atherosclerotic disease, myocardial infarction (MI), acute coronary syndrome and angina - is the most prevalent form of cardiovascular disease and is the largest subset of this mortality. Coronary artery disease (CAD) is a leading cause of death of women and men  worldwide. CAD’s impact on women traditionally has been underappreciated due to higher rates at younger ages in men. Microvascular coronary disease disproportionately affects women. Women have unique risk factors for CAD, including those related to pregnancy and autoimmune disease.DOI: http://dx.doi.org/10.3329/jom.v15i2.20687 J MEDICINE 2014; 15 : 135-140


2021 ◽  
Vol 14 (4) ◽  
pp. e239232
Author(s):  
Deeksha Kundapur ◽  
Siddarth Nosib ◽  
Shravan Nosib

The simultaneous occurrence of Takotsubo syndrome, congenital coronary artery anomaly and severe coronary artery disease is a rare clinical triad. This case report highlights the intricacies of management of this ‘triple jeopardy’ scenario.


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