scholarly journals The prospective mathematical idea satisfying both radiation hormesis under low radiation doses and linear non-threshold theory under high radiation doses

2020 ◽  
Vol 42 (1) ◽  
Author(s):  
Katsuhito Kino
Challenges ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 33
Author(s):  
Katsuhito Kino ◽  
Takayuki Ohshima ◽  
Hajime Takeuchi ◽  
Takanobu Kobayashi ◽  
Taishu Kawada ◽  
...  

The linear no-threshold (LNT) theory describes the linear relationship between a radiation dose and its effects. However, whether the linear relationship is maintained at low radiation doses has yet to be determined. Many previous studies support the radiation hormesis theory, which states that radiation has beneficial effects on health. In this viewpoint, we propose a mathematical function fitted to a model consistent with both the LNT at ≥100 mSv and radiation hormesis theories at <100 mSv, and the model requires a factor whose amount or activity takes a mountain-like shape versus the radiation dose and have one maximum value at 40.9 mSv. We searched a wide range of factors with these features based on searches on PubMed, and then evaluated whether these factors were suitable candidates consistent with both the LNT and radiation hormesis theories. Our consideration indicated that these factors did not completely follow the equation suggested at this time. Of course, other theories do not deny that these factors are involved in hormesis. However, based on our theory, still unknown factors may be involved in radiation hormesis, and then such unknown factors which are activated at <100 mSv should be searched.


1975 ◽  
Vol 149 (1) ◽  
pp. 289-291 ◽  
Author(s):  
G M Blackburn ◽  
P E Taussig

Anthracene becomes covalently bound to high-molecular-weight DNA in mammalian tissue culture as a result of irradiation at 365 nm after the incubation of cells with the hydrocarbon. At high radiation doses, the extent of binding exceeds one hydrocarbon molecule per 103 bases, and is lethal. At low radiation doses, much decreased binding is observed, but a majority of cells remain viable and can be recultured.


2002 ◽  
Vol 8 (5-6) ◽  
pp. 58-61
Author(s):  
V.V. Tsetlin ◽  
◽  
E.A. Deshevaya ◽  
N.D. Novikova ◽  
N.A. Polikarpov ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Zhonghua Sun ◽  
Aini AbAziz ◽  
Ahmad Khairuddin Md Yusof

Concerns about ionizing radiation during interventional cardiology have been increased in recent years as a result of rapid growth in interventional procedure volumes and the high radiation doses associated with some procedures. Noncancer radiation risks to cardiologists and medical staff in terms of radiation-induced cataracts and skin injuries for patients appear clear potential consequences of interventional cardiology procedures, while radiation-induced potential risk of developing cardiovascular effects remains less clear. This paper provides an overview of the evidence-based reviews of concerns about noncancer risks of radiation exposure in interventional cardiology. Strategies commonly undertaken to reduce radiation doses to both medical staff and patients during interventional cardiology procedures are discussed; optimisation of interventional cardiology procedures is highlighted.


2021 ◽  
Vol 94 (1126) ◽  
pp. 20210436 ◽  
Author(s):  
Beth A. Schueler ◽  
Kenneth A Fetterly

Data suggest that radiation-induced cataracts may form without a threshold and at low-radiation doses. Staff involved in interventional radiology and cardiology fluoroscopy-guided procedures have the potential to be exposed to radiation levels that may lead to eye lens injury and the occurrence of opacifications have been reported. Estimates of lens dose for various fluoroscopy procedures and predicted annual dosages have been provided in numerous publications. Available tools for eye lens radiation protection include accessory shields, drapes and glasses. While some tools are valuable, others provide limited protection to the eye. Reducing patient radiation dose will also reduce occupational exposure. Significant variability in reported dose measurements indicate dose levels are highly dependent on individual actions and exposure reduction is possible. Further follow-up studies of staff lens opacification are recommended along with eye lens dose measurements under current clinical practice conditions.


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