scholarly journals Sleep pattern in a group of patients undergoing hemodialysis compared to control

2022 ◽  
Vol 29 (1) ◽  
Author(s):  
Reem El Sayed Hashem ◽  
Tarek Asaad Abdo ◽  
Iman Ibrahim Sarhan ◽  
Amr Mohammed Mansour

Abstract Background Patients with chronic kidney disease progress regularly every year to end-stage renal disease and have to undergo dialysis. Sleep disturbances have been reported to be frequent among patients receiving dialysis and contributing to the increase of their mortality and morbidity. The present research aimed to study the sleep pattern in hemodialysis patients and the risk factors associated. This cross-sectional case-control study included 40 subjects divided into 2 groups: 20 cases recruited from Ain Shams University Hospital’s dialysis unit and 20 in the control group with normal Pittsburgh Sleep Quality Index score matched for age and sex. Both groups were subjected to overnight polysomnography, and the cases group was assessed by the Pittsburgh Sleep Quality Index to determine their sleep quality. Results Nearly all polysomnographic parameters were significantly abnormal in the cases group except for sleep onset latency (P > 0.05), showing obstructive sleep apnea and periodic limb movement (P value 0.001). Based on their Pittsburgh Sleep Quality Index score, 30% were classified as good sleepers and 70% as bad sleepers. On comparing both groups, a significant difference was found. Poor sleepers had more worse sleep efficiency (62.9%), spent longer time during their sleep in stage 1 (26.6%) with shorter REM onset latency (113.5 ± 99.5), and had a longer duration of illness with lower serum creatinine level compared to good sleepers. Conclusions The prevalence of obstructive sleep apnea and periodic limb movement in hemodialysis patients is high; patients with longer time on dialysis are at more risk of sleep disorders, whereas hemoglobin levels, BUN, and other demographic factors do not seem to play a role in sleep disorder. Hence, patients on hemodialysis need to be screened for sleep disorders so as to improve their mortality and morbidity.

2020 ◽  
Vol 26 (2) ◽  
Author(s):  
Mohamad Naim Bin Hasan ◽  
William William ◽  
Flora Rumiati

Kelebihan berat badan merupakan faktor independen yang berkontribusi terhadap kualitas tidur yang buruk. Sleep apnea merupakan timbulnya episode abnormal pada frekuensi napas yang berhubungan dengan penyempitan saluran napas atas pada saat tidur. Sleep apnea dapat berupa henti napas (apnea) atau menurunnya ventilasi yang akan menyebabkan gangguan bernapas saat tidur. Semakin besar nilai Indeks Massa Tubuh (IMT) atau bertambahnya berat badan, kemungkinan untuk mengalami Obstructive Sleep Apnea (OSA) semakin tinggi. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara IMT dengan kualitas tidur pada mahasiswa kedokteran angkatan 2016 FKIK Ukrida. Jenis penelitian yang digunakan adalah penelitian cross sectional dengan menggunakan studi komparatif, yaitu untuk mengetahui hubungan antara IMT dengan kualitas tidur pada mahasiswa golongan berat badan lebih dan berat badan normal. Teknik sampling yang digunakan dalam penelitian ini adalah purposive sampling. Sebanyak  88 responden berpartisipasi dalam penelitian ini, terdiri dari 44 mahasiswa yang mempunyai berat badan normal dan 44 mahasiswa yang mempunyai berat badan lebih. Responden mengisi kuesioner Pittsburgh Sleep Quality Index (PSQI).   Hasil penelitian menunjukkan sebanyak 64 responden (72,7%) mempunyai kualitas tidur buruk, dan 24 responden (27,3%) memiliki kualitas tidur yang baik, serta durasi tidur terbanyak adalah < 6 jam.  Berdasarkan uji Chi-Square, disimpulkan adanya hubungan antara berat badan dengan kualitas tidur (p = 0,000, p < 0,05) pada mahasiswa Fakultas Kedokteran angkatan 2016 FKIK Ukrida.


Respiration ◽  
2020 ◽  
pp. 1-8
Author(s):  
Kengo Ohtsuka ◽  
Rie Baba ◽  
Wakako Yamasawa ◽  
Ryutaro Shirahama ◽  
Yoichiro Hattori ◽  
...  

<b><i>Background:</i></b> Patients with obstructive sleep apnea syndrome (OSAS) experience excessive daytime sleepiness and insomnia and they are at risk of developing cardiovascular disease and stroke. Continuous positive airway pressure therapy could improve symptoms and decrease these risks; however, adherence is problematic. Although the oral appliance is another therapeutic option, patient satisfaction is limited and the effect of the nasal airway stent – a new device – remains unclear. <b><i>Objectives:</i></b> The aim of this study was to evaluate the effect of NAS therapy in patients with mild-to-moderate OSAS in a prospective, single-arm, interventional pilot study. <b><i>Method:</i></b> Patients with mild/moderate sleep apnea (<i>n</i> = 71; Apnea-Hypopnea Index [AHI], 5–20 events/h on polysomnography) were recruited. Sleep-associated events were measured using a portable device (WatchPAT200) pre- and immediately post-treatment and at 1 month follow-up. AHI (including supine and non-supine AHI), Oxygen Desaturation Index (ODI), Respiratory Disturbance Index (RDI), percutaneous oxygen saturation, heart rate, and snore volume were evaluated. Symptoms were assessed using the Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, and Hospital Anxiety and Depression Scale. <b><i>Results:</i></b> NAS use significantly improved AHI, supine AHI, RD, ODI, and snore volume compared to pre-intervention (<i>r</i> = 0.44, 0.48, 0.3, 0.42, and 0.34; <i>p</i> &#x3c; 0.001, <i>p</i> &#x3c; 0.001, <i>p</i> = 0.011, <i>p</i> &#x3c; 0.001, and <i>p</i> = 0.048, respectively). Additionally, 25 and 10% of patients showed complete and partial response for AHI, respectively; these improvements remained significant 1 month later. Pittsburgh Sleep Quality Index scores improved from 6.0 to 5.3 (<i>r</i> = 0.46, <i>p</i> = 0.022). <b><i>Conclusions:</i></b> NAS therapy reduced severity and snoring in patients with mild-to-moderate OSAS. Approximately 30% of patients did not tolerate NAS due to side effects.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A170-A171
Author(s):  
Kanlaya Panjapornpon ◽  
Narumol Luekitinun ◽  
Puncharat Luengwattanakit ◽  
Manatsanan Denthet ◽  
Tanadol Wonsa-Ardsakul ◽  
...  

Abstract Introduction The rate of positive airway pressure (PAP) adherences in obstructive sleep apnea (OSA) patients with PAP therapy has remains persistently low. Telemonitoring is a promising wireless technology to early detect of usage trouble and solve them simultaneously. We compare PAP compliance, Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ-10), Pittsburgh Sleep Quality Index (PSQI), heart rate and blood pressure in OSA patients with PAP therapy for 12 weeks between telemonitoring and protocol-based groups. Methods This is a prospective simple randomization (1:1) study, allocated into the telemonitoring and protocol-based groups, at Central Chest Institute of Thailand since June to November 2020. We recruited adult patients, who underwent split-night polysomnography (PSG), met diagnostic criteria of OSA by ICSD-3 and achieved optimal or good pressure. Demographics data, physiological sleep parameters and differences between groups were analyzed by using descriptive, paired t-test, and ANOVA. Results A total of ten OSA patients with PAP therapy were attended. Baseline characteristics between groups were compared, and it is apparent that among telemonitoring and protocol-based groups, most patients were male (60% in each group), the average age of patients were (45.60 ± 9.86 vs 41.60 ± 12.38, p = 0.588) years, body mass index (BMI) (24.66 ± 3.39 vs 30.21 ± 6.13, p = 0.114) km/m2, Epworth Sleepiness Scale (ESS) was (10.00 ± 2.92 vs 9.40 ± 3.57, p = 0.779), apnea-hypopnea index (AHI) of (60.06 ± 31.08 vs 77.98 ± 43.17, p = 0.473) events/hour, and PAP pressure usage (10.20 ± 3.71 vs 10.00 ± 3.67, p = 0.933) cmH2O. There was no significant difference between groups in clinical parameters, sleep questionnaires and PAP compliance of obstructive sleep apnea (OSA) patients with PAP therapy for 12 weeks. However, in telemonitoring group, PSQI compared among baseline, fourth and twelfth week were significantly improved (7.60 ± 2.71 vs 5.00 ± 2.00 vs 4.00 ± 1.00 respectively, p = 0.041). Conclusion Using telemonitoring-guided intervention causes significantly improved in Pittsburgh Sleep Quality Index in severe obstructive sleep apnea patients with PAP therapy for 12 weeks. There was no significant difference in PAP compliance between telemonitoring and protocol-based groups. Support (if any):


2018 ◽  
Vol 13 (2) ◽  
pp. 46
Author(s):  
Putwi Rizki Sakinah ◽  
Cecep Eli Kosasih ◽  
Eka Afrima Sari

AbstractPeople with hypertension experience symptoms of dizziness, headache, obstructive sleep apnea, shortness of breath, nocturia, and restless legs syndrome which disturb sleep and reduce its quality. This research’s objective was to describe the sleep quality overview of Puskesmas Rancaekek’s hypertension patients. Using descriptive quantitative method with purposive sampling technique, this research aimed at 79 Puskesmas Rancaekek’s patients who had been diagnosed with hypertension for at least one month long. The data were collected using the Pittsburgh Sleep Quality Index (PSQI) questionnaire and analysed using the total score resulted; ≤5 was good while >5 was poor. Results showed 94.6% of respondents had poor sleep quality. The dimensions that contribute to the poor sleep quality included >30 minutes sleep latency, <5 hours sleep duration, <65% of sleep efficiency, sleep disturbance due to waking up at midnight or early morning and waking up to toilet, and activity disturbance at daylight. The conclusion was that Puskesmas need to develop preventive and promotive efforts to minimize the complication of hypertension patients and optimize their quality of life by helping them improve their quality of sleep. Meanwhile, the self-management that should be done by the patients were avoiding the consumption of coffee and cigarettes, limiting physical activities, and doing physical exercise and relaxation therapies. Key Words: Hypertension, Sleep Quality, PSQI  AbstrakPenderita hipertensi mengalami gejala pusing, nyeri kepala, obstructive sleep apnea, sesak napas, nokturia, restless legs syndrome yang mengganggu tidur dan berdampak pada kualitas tidur serta mempengaruhi kualitas hidup dan tekanan darah. Penelitian bertujuan untuk melihat gambaran kualitas tidur pada penderita hipertensi di Puskesmas Rancaekek. Metode penelitian menggunakan deskriptif kuantitatif dengan teknik purposive sampling sebanyak 79 penderita hipertensi di Puskesmas Rancaekek yang telah didiagnosis dokter minimal 1 bulan. Pengambilan data menggunakan kuesioner Pittsburgh Sleep Quality Index (PSQI) dan dianalisis menggunakan total skor, jika skor ≤ 5 baik dan skor > 5 buruk. Hasil menunjukan 94,6% responden memiliki kualitas tidur buruk. Dimensi yang berkontribusi terhadap kualitas tidur buruk yaitu latensi tidur tidak dapat tertidur dalam waktu 30 menit, durasi tidur <5 jam, efisiensi kebiasaan tidur <65%, gangguan tidur karena terbangun tengah malam atau pagi sekali dan terbangun karena ingin ke toilet, serta gangguan aktivitas pada siang hari. Puskesmas perlu mengembangkan upaya preventif dan promotif untuk meminimalisir komplikasi penderita hipertensi dan pencapaian kualitas hidup optimal salah satunya dengan membantu meningkatkan kualitas tidur. Dengan mengedukasi penderita untuk menghindari konsumsi kopi dan rokok, membatasi aktivitas fisik, melakukan latihan fisik, dan terapi relaksasi. Kata Kunci: Hipertensi, Kualitas Tidur, PSQI


2020 ◽  
Vol 9 (6) ◽  
pp. 1821 ◽  
Author(s):  
Tetsuro Hoshino ◽  
Ryujiro Sasanabe ◽  
Kenta Murotani ◽  
Reiko Hori ◽  
Mamiko Mano ◽  
...  

Rapid eye movement (REM)-related obstructive sleep apnea (OSA), a polysomnographic phenotype that affects 12–36% of OSA patients, is defined by apnea and hypopnea events that predominantly or exclusively occur during REM sleep. Recent studies indicated that REM-related OSA was associated with the development of nocturnal non-dipping of systolic and diastolic blood pressure, metabolic syndrome, diabetes, and depressive symptoms. However, to date, the association between REM-related OSA and insomnia still remains unclear. We investigated whether there was a difference between REM- and non-REM-related OSA in terms of insomnia-related sleep disturbance as measured by the Pittsburgh Sleep Quality Index (PSQI) in 1736 patients with OSA. REM-related OSA showed a significant association with increased PSQI in all adjusted models. In the subgroup analysis, the coefficients of all models were higher in female than in male patients with REM-related OSA. Insomnia should be considered an important complaint in patients with REM-related OSA, and its indicators, such as the PSQI, should be included in routine diagnostic testing.


Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 211
Author(s):  
Faiza Kalam ◽  
Kelsey Gabel ◽  
Sofia Cienfuegos ◽  
Mark Ezpeleta ◽  
Eric Wiseman ◽  
...  

Background: Alternate day fasting combined with a low carbohydrate diet (ADF-LC) is an effective weight loss regimen. Whether the weight loss induced by ADF-LC can improve sleep, remains unknown. Objective: This study examined the effect an ADF-LC diet on sleep quality, duration, insomnia severity and the risk of obstructive sleep apnea. Methods: Adults with obesity (n = 31) participated in ADF (600 kcal “fast day”; ad libitum intake “feast day”) with a low-carbohydrate diet (30% carbohydrates, 35% protein, and 35% fat). The 6-month trial consisted of a 3-month weight loss period followed by a 3-month weight maintenance period. Results: Reductions in body weight (−5 ± 1 kg, p < 0.001) and fat mass (−4 ± 1 kg, p < 0.01) were noted during the weight loss period, and these reductions were sustained during the weight maintenance period. Lean mass and visceral fat remained unchanged. The Pittsburgh Sleep Quality Index (PSQI) score indicated poor sleep quality at baseline (6.4 ± 0.7) with no change by month 3 or 6, versus baseline. ISI score indicated subthreshold insomnia at baseline (8.5 ± 1.0), with no change by month 3 or 6, versus baseline. The percent of subjects with high risk of obstructive sleep apnea at baseline was 45%, with no change by month 3 or 6. Wake time, bedtime, and sleep duration remained unchanged. Conclusion: The ADF-LC diet does not impact sleep quality, duration, insomnia severity or the risk of obstructive sleep apnea in adults with obesity.


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