Leucotomy in the Periodic Psychoses

1949 ◽  
Vol 95 (398) ◽  
pp. 101-114 ◽  
Author(s):  
G. N. Jones ◽  
P. K. McCowan
Keyword(s):  
Prefrontal Cortex ◽  
Large Body ◽  
Endocrine System ◽  
Small Contribution ◽  
Animal Kingdom ◽  
Body Of Knowledge ◽  
Human Economy ◽  
Similar Report ◽  
Made In

Periodicity as a phenomenon in nature has been known and studied from time immemorial, Astronomy and other sciences have built up a large body of knowledge which goes a long way towards explaining periodicity in the spheres with which they concern themselves. As it appears in the animal kingdom, however, the mechanisms underlying the phenomenon are still largely unrevealed. Of late years the hypothesis has been advanced that many of the periodic happenings in the human economy are subserved by the hypothalamus. Thus menstrual periodicity is held to be due to the hypothalamus acting in conjunction with the endocrine system. This paper is a small contribution to this hypothesis, maintaining as it does that the periodicity observed in certain psychoses is due to the influence of the hypothalamus on the prefrontal cortex. So far no similar report has been made in the large literature dealing with leucotomy and it therefore seemed worth while to give our results in some detail.

AN ONTOLOGY FOR UNDERSTANDING AND APPLYING OBJECT-ORIENTED DESIGN KNOWLEDGE

2007 ◽  
Vol 17 (03) ◽  
pp. 407-421 ◽  
Author(s):  
JAVIER GARZÁS ◽  
MARIO PIATTINI
Keyword(s):  
Software Maintenance ◽  
Large Body ◽  
Object Oriented ◽  
Lessons Learned ◽  
Design Knowledge ◽  
Object Oriented Design ◽  
Body Of Knowledge ◽  
Software Engineers ◽  
Object Oriented Systems ◽  
Made In

After years of experience in object-oriented design, software engineers have accumulated a great deal of knowledge in the design and construction of object-oriented systems: important contributions to this field including principles, heuristics, lessons learned, bad smells, refactorings, and so on, with the resultant major improvements in software development. However, this large body of knowledge is still not well organized, its terminology is ambiguous, and it is very difficult to make practical use of the contributions made. In this regard, we believe it is important to define an ontology in order to structure and unify design knowledge, since a good understanding of the experience derived from practical work is critical for software engineers. This ontology could be used to improve communication between software engineers, inter-operability among designs, design re-usability, design knowledge searching and specification, software maintenance, knowledge acquisition, etc. In the ontology we incorporate knowledge specific to both domain and technology. Such an organized body of knowledge could also be used for registering and documenting design rationale issues.

Finance and Investment: The European Case

2018 ◽  
Keyword(s):  
Sovereign Debt ◽  
Large Body ◽  
Policy Research ◽  
Financial System ◽  
Research Programme ◽  
Policy Formulation ◽  
Contributory Factor ◽  
Data Sets ◽  
Equity Financing ◽  
Body Of Knowledge

This book is the product of a two-year research programme entitled Restarting European Long-Term Investment Finance (RELTIF), organized by Assonime and the Centre for Economic Policy Research (CEPR) in London. The programme brought together leading researchers from across the world to consider the causes of the persistently low level of investment in Europe, to examine the extent to which the financial system was a contributory factor and to identify possible policy remedies for it. It considered the relation of finance to corporate sector investment, the lending behaviour of banks, the provision of equity financing, the role of public sector institutions, regulation, and taxation. The chapters in this volume provide one of the most comprehensive and thorough analyses of any financial system that has been undertaken to date. They reflect a large body of research using new and existing data sets, employing advanced empirical tools, and exploiting the unique insights provided by the tumultuous events of the financial and sovereign debt crises. Together they comprise an exceptional body of knowledge to advance academic thinking and guide policy formulation in the future.

The case for NLP-enhanced database tuning

2021 ◽  
Vol 14 (7) ◽  
pp. 1159-1165
Author(s):  
Immanuel Trummer
Keyword(s):  
Natural Language ◽  
Language Processing ◽  
Large Body ◽  
Prototype System ◽  
Web Documents ◽  
Natural Language Text ◽  
Body Of Knowledge ◽  
Challenges And Opportunities ◽  
Automated Tuning ◽  
Database Tuning

A large body of knowledge on database tuning is available in the form of natural language text. We propose to leverage natural language processing (NLP) to make that knowledge accessible to automated tuning tools. We describe multiple avenues to exploit NLP for database tuning, and outline associated challenges and opportunities. As a proof of concept, we describe a simple prototype system that exploits recent NLP advances to mine tuning hints from Web documents. We show that mined tuning hints improve performance of MySQL and Postgres on TPC-H, compared to the default configuration.

Modelling Economic Consequences of ICT Infrastructure Failure in Support of Critical Infrastructure Protection Policies

2013 ◽  
pp. 115-138
Author(s):  
Olaf Jonkeren ◽  
David Ward
Keyword(s):  
Critical Infrastructure ◽  
Large Body ◽  
Economic Consequences ◽  
Critical Infrastructures ◽  
Critical Infrastructure Protection ◽  
Infrastructure Protection ◽  
Modelling Methodology ◽  
Infrastructure Failure ◽  
Ict Infrastructure ◽  
Made In

There is a large body of work and effort been made in the modelling of critical infrastructures (CI’s) by academia, enterprises, stakeholders, operators, etc.; however, their endeavours have received mixed success so far. This can be traced back to several difficult and historical hurdles in CI modeling such as the chronic unavailability of reliable and recognised data, the specificity of the resulting model, and therefore, its application, the underlying mathematics, narrow-mindedness and lack of awareness of the consequences of infrastructure failure, the recognition and dissemination of the modelling methodology-knowledge, etc. Consequently, bridging theory and application and providing tools for analysing CI’s is key to ensuring that such modelling delivers the benefits voiced and satisfies the needs raised. This chapter sets out to tackle several of these issues.

The contribution of epidemiology to psychiatric aetiology

2012 ◽  
pp. 280-290
Author(s):  
Scott Henderson
Keyword(s):  
Psychiatric Disorders ◽  
Genetic Information ◽  
Large Body ◽  
Environmental Exposures ◽  
Human Populations ◽  
Body Of Knowledge

The epidemiology of psychiatric disorders has shown the extent to which these are present in all human populations. It has also provided a large body of knowledge about aetiology. Now that biological including genetic information can be added to data on environmental exposures, opportunities for further advancement carry much promise.

scholarly journals Cholera El Tor in Infants below 2 Years of Age as seen in Private and Hospitalized Patients

2017 ◽  
Vol 19 (3-4) ◽  
pp. 79
Author(s):  
Haroen Noerasid ◽  
Pitono Soeparto ◽  
Bing Rudianto ◽  
Hananto Wirjo ◽  
Juliati Sudanawidjaja ◽  
...  
Keyword(s):  
Private Practice ◽  
Hospitalized Patients ◽  
Pediatric Ward ◽  
Positive Stool ◽  
Disease Pattern ◽  
Similar Report ◽  
One Year ◽  
El Tor ◽  
Stool Cultures ◽  
Made In

A report was made on cholera El Tor in children under 2 years of age with mute gastroenteritis admitted to the pediatric ward of the Dr. Soetomo Hospital, Surabaya. Twenty-three out of 115 cases (20%) showed positive stool cultures. A similar report was made in the same period on patients with gastroenteritis in private practice. Four out of 108 cases (3.6%) showed positive stool cultures. A brief description of the disease pattern of infantile gastroenteritis was presented. The increasing incidence of cholera, below one year was also discussed.

scholarly journals Star Formation: From OB Associations to Protostars

1987 ◽  
Vol 115 ◽  
pp. 1-18 ◽  
Author(s):  
Charles J. Lada
Keyword(s):  
Star Formation ◽  
Stellar Evolution ◽  
Large Body ◽  
Apparent Paradox ◽  
International Astronomical ◽  
Critical Experiment ◽  
History Of ◽  
The Subject ◽  
Astrophysical Research ◽  
Made In

The study of star formation is a relatively young discipline of the field of astronomy. Up until the mid point of the twentieth century only a most rudimentary understanding of the subject was possible. This is because prior to that time there did not exist any substantive body of empirical data which could be used to critically test even the most basic hypotheses concerning stellar origins. However, as a result of impressive advances in observational technology and in our understanding of stellar evolution during the last forty years, the subject of star formation has developed into one of the most important branches of modern astrophysical research. A large body of observational data and a considerable literature pertaining to this subject now exist and a significant fraction of the international astronomical community devotes their efforts towards trying to comprehend the origins of stars and planets. Yet, despite these efforts we have yet to observationally identify, with any certainty, a single object in the process of stellar birth! Moreover, we have not yet produced a viable theory of star formation, one capable of being tested and refined by critical experiment. In many ways, stellar birth is as much a mystery today as it was forty years ago. However, there can be little doubt that during the last two decades truly revolutionary progress has been made in the quest to understand the star formation process in our galaxy. This apparent paradox in the state of our knowledge concerning stellar origins is resolved with the realization that the history of the study of star formation has been a history of the study of progressively earlier and earlier stages of stellar evolution. Indeed, it is in precisely this area of endeavor that we have learned so much.

Understanding Project Data

2008 ◽  
pp. 303-374
Author(s):  
Emilia Mendes
Keyword(s):  
Large Body ◽  
Statistical Techniques ◽  
Effort Estimation ◽  
Estimation Techniques ◽  
Body Of Knowledge ◽  
Project Data ◽  
Estimation Models

The objective of this chapter is to provide an introduction to statistical techniques and concepts that are frequently used when dealing with data for effort estimation. The concepts presented here are in no way exhaustive since statistics comprises a very large body of knowledge where entire books are devoted to specific topics. The parts that are the focus of this chapter are those that are necessary to use when building effort estimation models, and also when comparing different effort estimation techniques.

The Object-Oriented Design Knowledge

2011 ◽  
pp. 1-7
Author(s):  
Javier Garzas ◽  
Mario Piattini
Keyword(s):  
Software Engineering ◽  
Best Practices ◽  
Design Patterns ◽  
Architectural Design ◽  
Large Body ◽  
Object Oriented ◽  
Design Knowledge ◽  
Object Oriented Design ◽  
Body Of Knowledge

In order to establish itself as a branch of engineering, a profession must understand its accumulated knowledge. In this regard, software engineering has advanced greatly in recent years, but it still suffers from the lack of a structured classification of its knowledge. In this sense, in the field of object-oriented micro-architectural design designers have accumulated a large body of knowledge and it is still have not organized or unified. Therefore, items such as design patterns are the most popular example of accumulated knowledge, but other elements of knowledge exist such as principles, heuristics, best practices, bad smells, refactorings, and so on, which are not clearly differentiated; indeed, many are synonymous and others are just vague concepts.

scholarly journals Knowing the Enemy: Inducible Defences in Freshwater Zooplankton

Diversity ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 147 ◽  
Author(s):  
Patricia Diel ◽  
Marvin Kiene ◽  
Dominik Martin-Creuzburg ◽  
Christian Laforsch
Keyword(s):  
Life History ◽  
Chemical Cues ◽  
Prey Species ◽  
Inducible Defences ◽  
Animal Kingdom ◽  
Predator Species ◽  
Freshwater Zooplankton ◽  
Taxonomic Range ◽  
Set Up ◽  
Made In

Phenotypic plasticity in defensive traits is an appropriate mechanism to cope with the variable hazard of a frequently changing predator spectrum. In the animal kingdom these so-called inducible defences cover the entire taxonomic range from protozoans to vertebrates. The inducible defensive traits range from behaviour, morphology, and life-history adaptations to the activation of specific immune systems in vertebrates. Inducible defences in prey species play important roles in the dynamics and functioning of food webs. Freshwater zooplankton show the most prominent examples of inducible defences triggered by chemical cues, so-called kairomones, released by predatory invertebrates and fish. The objective of this review is to highlight recent progress in research on inducible defences in freshwater zooplankton concerning behaviour, morphology, and life-history, as well as difficulties of studies conducted in a multipredator set up. Furthermore, we outline costs associated with the defences and discuss difficulties as well as the progress made in characterizing defence-inducing cues. Finally, we aim to indicate further possible routes in this field of research and provide a comprehensive table of inducible defences with respect to both prey and predator species.

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