Impact of positive peritoneal cytology on the survival of early stage endometrial cancer

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5032-5032
Author(s):  
P. M. Tebeu ◽  
Y. Popowski ◽  
H. M. Verkooijen ◽  
C. Bouchardy ◽  
F. Ludicke ◽  
...  
2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 5032-5032
Author(s):  
P. M. Tebeu ◽  
Y. Popowski ◽  
H. M. Verkooijen ◽  
C. Bouchardy ◽  
F. Ludicke ◽  
...  

2020 ◽  
Vol 59 (3) ◽  
pp. 125-128
Author(s):  
Yoko NISHIMURA ◽  
Motoki MATSUURA ◽  
Masato TAMATE ◽  
Noriko TERADA ◽  
Seiro SATOHISA ◽  
...  

2004 ◽  
Vol 91 (4) ◽  
pp. 720-724 ◽  
Author(s):  
P-M Tebeu ◽  
Y Popowski ◽  
H M Verkooijen ◽  
C Bouchardy ◽  
F Ludicke ◽  
...  

2013 ◽  
Vol 128 (1) ◽  
pp. 77-82 ◽  
Author(s):  
Gunjal Garg ◽  
Feng Gao ◽  
Jason D. Wright ◽  
Andrea R. Hagemann ◽  
David G. Mutch ◽  
...  

2021 ◽  
Vol 19 (2) ◽  
Author(s):  
A. K. Padhy ◽  
Mahapatra Manoranjan ◽  
Mishra Jagannath ◽  
Subhashree Rout ◽  
Mohapatra Janmejay ◽  
...  

2016 ◽  
Author(s):  
Seema Singhal ◽  
Sunesh Kumar Jain ◽  
D. N. Sharma ◽  
Sandeep Mathur ◽  
Juhi Bharti ◽  
...  

Aim: The study objectives were evaluation of clinicopathological characteristics, correlations between the preoperative and postoperative tumor assessment in early stage endometrial cancer. Materials and Methods: We conducted a prospective descriptive study of 30 cases of endometrial cancer stage 1 examined and treated at a tertiary care teaching institute between the years 2014-15. Results: The patients’ mean age at the time of diagnosis was 56.4 years. The mean parity was two. Postmenopausal bleeding with or without abnormal vaginal discharge was the most frequent symptom; it was present in 84.7% of patients. Co morbidities like hypertension and diabetes were seen in 65% of women. 6/30 patients had family history of some malignancy. All the patients underwent Type I extrafascial hysterectomy with bilateral salpingo oophorectomy, one case had Type I extrafascial hysterectomy with infracolic omentectomy. A total of 10.6% cases had lymph nodes metastasis and none of these patients had ovarian metastasis or positive peritoneal cytology. None of the patients with superficial myometrial invasion (MI) had lymph node metastasis. None of the cases showed positive peritoneal cytology. Staging upgraded fom 1a to 1b in 50% of subjects after final histopathological analysis. One patient who was operated as endometrial hyperplasia with atypia actually had endometrial adenocarcinoma in the postoperative specimen. Conclusions: There is a poor correlation between the preoperative and the postoperative tumor assessment.


2021 ◽  
Vol 11 ◽  
Author(s):  
Salvatore Gueli Alletti ◽  
Emanuele Perrone ◽  
Camilla Fedele ◽  
Stefano Cianci ◽  
Tina Pasciuto ◽  
...  

ObjectiveThis prospective randomized trial aimed to assess the impact of the uterine manipulator in terms of lymph vascular space invasion (LVSI) in patients undergoing minimally invasive staging for early-stage endometrial cancer.MethodsIn this multicentric randomized trial, enrolled patients were randomly allocated in two groups according to the no use (arm A) or the use (arm B) of the uterine manipulator. Inclusion criteria were G1-G2 early-stage endometrial cancer at preoperative evaluation. The variables collected included baseline demographic characteristics, perioperative data, final pathology report, adjuvant treatment, and follow-up.ResultsIn the study, 154 patients (76 in arm A and 78 in arm B) were finally included. No significant differences were recorded regarding the baseline characteristics. A statistically significant difference was found in operative time for the laparoscopic staging (p=0.005), while no differences were reported for the robotic procedures (p=0.419). The estimated blood loss was significantly lower in arm A (p=0.030). No statistically significant differences were recorded between the two study groups in terms of peritoneal cytology, LVSI (p=0.501), and pattern of LVSI (p=0.790). No differences were detected in terms of overall survival and disease-free survival (p=0.996 and p=0.480, respectively). Similarly, no differences were recorded in the number of recurrences, 6 (7.9%) in arm A and 4 (5.2%) in arm B (p=0.486). The use of the uterine manipulator had no impact on DFS both at univariable and multivariable analyses.ConclusionsThe intrauterine manipulator does not affect the LVSI in early-stage endometrial cancer patients undergoing laparoscopic/robotic staging.Clinical Trial Registrationhttps://clinicaltrials.gov, identifier (NCT: 02762214)


2016 ◽  
Author(s):  
Seema Singhal ◽  
Sunesh Kumar Jain ◽  
D. N. Sharma ◽  
Sandeep Mathur ◽  
Juhi Bharti ◽  
...  

Aim: The study objectives were evaluation of clinicopathological characteristics, correlations between the preoperative and postoperative tumor assessment in early stage endometrial cancer. Materials and Methods: We conducted a prospective descriptive study of 30 cases of endometrial cancer stage 1 examined and treated at a tertiary care teaching institute between the years 2014-15. Results: The patients’ mean age at the time of diagnosis was 56.4 years. The mean parity was two. Postmenopausal bleeding with or without abnormal vaginal discharge was the most frequent symptom; it was present in 84.7% of patients. Co morbidities like hypertension and diabetes were seen in 65% of women. 6/30 patients had family history of some malignancy. All the patients underwent Type I extrafascial hysterectomy with bilateral salpingo oophorectomy, one case had Type I extrafascial hysterectomy with infracolic omentectomy. A total of 10.6% cases had lymph nodes metastasis and none of these patients had ovarian metastasis or positive peritoneal cytology. None of the patients with superficial myometrial invasion (MI) had lymph node metastasis. None of the cases showed positive peritoneal cytology. Staging upgraded from 1a to 1b in 50% of subjects after final histopathological analysis. One patient who was operated as endometrial hyperplasia with atypia actually had endometrial adenocarcinoma in the postoperative specimen. Conclusions: There is a poor correlation between the preoperative and the postoperative tumor assessment.


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