Use of Port-A-Cath in pediatric cancer patients: Experience from a tertiary cancer center in south India

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20747-e20747
Author(s):  
T. Singh ◽  
C. Satheesh ◽  
J. Ankit ◽  
K. V. Sajeevan ◽  
L. Appaji ◽  
...  

e20747 Background: Implanted subcutaneous (s.c.) central venous port accesses including Port-A-Cath (PAC) facilitate the administration of chemotherapy or blood products and are frequently used in children with cancer. We present our experience of PACs in paediatric cancer patients from a tertiary cancer centre in South India. Methods: A total of 20 patients with paediatric malignancies requiring PAC were included in the study. Aim was to review our experience of PAC and analyse the outcome in paediatric cancer patients in Indian setting. A record of all complications and final outcome were analysed. Results: A total of 20 PAC were placed. Disease distribution included ALL(80%), AML(5%), NHL(5%), neuroblastoma (5%) and RMS (5%). PAC has been in place for 2 to 36 months (cumulative 400 months). Portal infection (Coagulase-negative staphylococci) was observed in four patients of whom 3 patients had their PAC removed (portal occlusion also seen in one of the pt). Conclusions: Although, catheter-related infections demanded PAC removal in 15% of our patients, their benefits (excluding cost 300 $) argue for continued PAC use in the paediatric cancer population as it is safe and has many advantages compared to traditional CVCs in use. Strict indications, meticulous implantation technique, and adequate handling are, however, mandatory. No significant financial relationships to disclose.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sungmin Woo ◽  
Abdallah Araji ◽  
Mohammad Ali El Amine ◽  
Natalie Gangai ◽  
Elizabeth Acquafredda ◽  
...  

Abstract Background To assess the spectrum and frequency of modalities used for emergency room (ER) imaging and their findings in pediatric cancer patients and assess their relationship with survival. Methods Consecutive pediatric cancer patients that underwent imaging during an ER visit at our tertiary cancer center over a 5-year period were retrospectively analyzed. Imaging findings were considered positive when they were relevant to the ER presenting complaint. Imaging positivity was correlated with inpatient admission. Overall survival (OS) was assessed with Kaplan-Meier curves and uni- and multi-variate Cox proportional hazards model was used to identify significant factors associated with OS. Results Two hundred sixty-one patients (135 males and 126 females; median age 11 years [interquartile range 5–16 years] with 348 visits and a total of 406 imaging studies were included. Common chief complaints were related to the chest (100 [28.7 %]) and fever (99 [28.4 %]). ER imaging was positive in 207 visits (59.5 %), commonly revealing increased metastases (50 [14.4 %]), pneumonia (47 [13.5 %]), and other lung problems (12 [2.9 %]). Positive ER imaging was associated with inpatient admission (69.3 % [133/192] vs. 40.4 % [63/156], p < 0.01). Multivariate survival analysis showed that positive ER imaging (hazard ratio [HR] = 2.35 [95% CI 1.44–3.83, p < 0.01), admission (HR = 1.86 [95% CI 1.17–3.00], p < 0.01), number of ER visits (HR = 3.08 [95% CI 1.62–5.83], p < 0.01 for ≥ 3 visits) were associated with poorer survival. Conclusions Imaging was able to delineate the cause for ER visits in children with cancer in over half of the cases. Positive ER imaging was associated with admission and worse survival.


Author(s):  
Binitha Rajeswari ◽  
Chellapan Sojamani Guruprasad ◽  
Manjusha Nair ◽  
Varikkattu Rajendran Prasanth ◽  
Bhaskar Subin Sugath ◽  
...  

2019 ◽  
Vol 8 (3) ◽  
pp. 119
Author(s):  
KR Anila ◽  
K Ramadas ◽  
ElizabethMathew Iype ◽  
TR Preethi ◽  
Anitha Mathews ◽  
...  

2000 ◽  
Vol 18 (14) ◽  
pp. 2755-2761 ◽  
Author(s):  
Pierre-Yves Crémieux ◽  
Barbara Barrett ◽  
Kenneth Anderson ◽  
Mitchell B. Slavin

PURPOSE: To determine the cost of outpatient RBC transfusion from the provider’s perspective at a major urban, academic cancer center. PATIENTS AND METHODS: We retrospectively studied 517 cancer patients with hematologic or solid tumors who received blood during fiscal year 1995 to 1996. A process-flow diagram was developed, and cost and utilization data for 12 months were collected and analyzed. A structured interview process was used to identify all direct and indirect costs from within the inpatient unit, blood bank, and outpatient clinic. Average costs were computed for the entire sample and for specific subgroups. RESULTS: In 1998 dollars, the average cost per RBC unit was $469 for adults and $568 for pediatric cancer patients. Adults and children generally received two and one RBC units per transfusion, respectively. Therefore, the average cost of a two-unit transfusion was $938 for adults. Patients with hematologic tumors required more RBC units (7.1 RBC units per year) at a higher average cost ($512 per RBC unit) than patients with solid tumors (4.7 RBC units per year, $474 per RBC unit). Further variations across tumor types were observed. Overhead, direct material, and direct labor represented 46%, 19%, and 35% of total costs respectively. CONCLUSION: The cost of outpatient RBC transfusions in cancer patients is higher than previously reported, in part because overhead costs and fixed costs might have been underestimated in previous studies. Furthermore, age, tumor type, and geographic variations in the cost of fixed assets and labor have a substantial impact on the cost of blood. The results indicate that the cost-effectiveness of alternatives to transfusions in the management of cancer patients may have been underestimated in the existing literature.


2018 ◽  
Vol 37 (3) ◽  
pp. 133-138 ◽  
Author(s):  
D. Lokanatha ◽  
Abhishek Anand ◽  
K. C. Lakshmaiah ◽  
K. Govind Babu ◽  
Linu Abraham Jacob ◽  
...  

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