scholarly journals Impact of Cancer on Work and Education Among Adolescent and Young Adult Cancer Survivors

2012 ◽  
Vol 30 (19) ◽  
pp. 2393-2400 ◽  
Author(s):  
Helen M. Parsons ◽  
Linda C. Harlan ◽  
Charles F. Lynch ◽  
Ann S. Hamilton ◽  
Xiao-Cheng Wu ◽  
...  

Purpose To examine the impact of cancer on work and education in a sample of adolescent and young adult (AYA) patients with cancer. Patients and Methods By using the Adolescent and Young Adult Health Outcomes and Patient Experience Study (AYA HOPE)—a cohort of 463 recently diagnosed patients age 15 to 39 years with germ cell cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, sarcoma, and acute lymphocytic leukemia from participating Surveillance, Epidemiology, and End Results (SEER) cancer registries—we evaluated factors associated with return to work/school after cancer diagnosis, a belief that cancer had a negative impact on plans for work/school, and reported problems with work/school after diagnosis by using descriptive statistics, χ2 tests, and multivariate logistic regression. Results More than 72% (282 of 388) of patients working or in school full-time before diagnosis had returned to full-time work or school 15 to 35 months postdiagnosis compared with 34% (14 of 41) of previously part-time workers/students, 7% (one of 14) of homemakers, and 25% (five of 20) of unemployed/disabled patients (P < .001). Among full-time workers/students before diagnosis, patients who were uninsured (odds ratio [OR], 0.21; 95% CI, 0.07 to 0.67; no insurance v employer-/school-sponsored insurance) or quit working directly after diagnosis (OR, 0.15; 95% CI, 0.06 to 0.37; quit v no change) were least likely to return. Very intensive cancer treatment and quitting work/school were associated with a belief that cancer negatively influenced plans for work/school. Finally, more than 50% of full-time workers/students reported problems with work/studies after diagnosis. Conclusion Although most AYA patients with cancer return to work after cancer, treatment intensity, not having insurance, and quitting work/school directly after diagnosis can influence work/educational outcomes. Future research should investigate underlying causes for these differences and best practices for effective transition of these cancer survivors to the workplace/school after treatment.

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
S Torp ◽  
Å Valle-Olsen ◽  
B Brusletto

Abstract Background Due to improved cancer treatment, the survival rate of cancer is increasing Unfortunately, many cancer survivors suffer from serious late effects because of this treatment. Therefore, more and more cancer survivors with reduced work ability are, and will in the future be, in work. To include this group of workers in working life is a challenge for the society in general and for the enterprises in particular. The aim of this study was to investigate managers’ experiences regarding cancer survivors’ return to work (RTW). Methods We performed qualitative individual in-depth interviews with nine managers who had experience with workers who needed adaptations at work after cancer treatment. The interviews were transcribed in verbatim and thematically analyzed in accordance with guidelines for stepwise deductive-inductive analysis (Tjora, 2016). Results All managers emphasized the importance of taking good care of workers with serious diseases and to adapt work according to their work ability. The managers tried to follow the Work Environment Act and guidelines given by the Norwegian Labor and Welfare Administration but they experienced that the guidelines did not fit well with the needs of the cancer survivor and/or the enterprise. A good RTW process was dependent on an open dialog that was initiated early in the RTW trajectory to establish a sense of safe situation for both the cancer survivor and the company. A good RTW process could only be established if the colleagues of the survivor gave their support to both the survivor and the manager. In addition, it was of great importance that the needs of the cancer survivor had to be balanced by the production needs of the enterprise. Conclusions Managers need support from health personnel and social security agencies to support cancer survivors to retain work. Key messages Cancer survivors need adaptations at work. Managers are crucial in securing a successful vocational rehabilitation of cancer survivors.


Author(s):  
Alexa C O Medica ◽  
Brian W Whitcomb ◽  
Ksenya Shliakhsitsava ◽  
Andrew C Dietz ◽  
Kelsey Pinson ◽  
...  

Abstract Context Although stages of reproductive aging for women in the general population are well described by STRAW+10 criteria, this is largely unknown for female adolescent and young adult cancer survivors (AYA survivors). Objective This work aimed to evaluate applying STRAW + 10 criteria in AYA survivors using bleeding patterns with and without endocrine biomarkers, and to assess how cancer treatment gonadotoxicity is related to reproductive aging stage. Design The sample (n = 338) included AYA survivors from the Reproductive Window Study cohort. Menstrual bleeding data and dried-blood spots for antimüllerian hormone (AMH) and follicle-stimulating hormone (FSH) measurements (Ansh DBS enzyme-linked immunosorbent assays) were used for reproductive aging stage assessment. Cancer treatment data were abstracted from medical records. Results Among participants, mean age 34.0 ± 4.5 years and at a mean of 6.9 ± 4.6 years since cancer treatment, the most common cancers were lymphomas (31%), breast (23%), and thyroid (17%). Twenty-nine percent were unclassifiable by STRAW + 10 criteria, occurring more frequently in the first 2 years from treatment. Most unclassifiable survivors exhibited bleeding patterns consistent with the menopausal transition, but had reproductive phase AMH and/or FSH levels. For classifiable survivors (48% peak reproductive, 30% late reproductive, 12% early transition, 3% late transition, and 7% postmenopause), endocrine biomarkers distinguished among peak, early, and late stages within the reproductive and transition phases. Gonadotoxic treatments were associated with more advanced stages. Conclusions We demonstrate a novel association between gonadotoxic treatments and advanced stages of reproductive aging. Without endocrine biomarkers, bleeding pattern alone can misclassify AYA survivors into more or less advanced stages. Moreover, a large proportion of AYA survivors exhibited combinations of endocrine biomarkers and bleeding patterns that do not fit the STRAW + 10 criteria, suggesting the need for modified staging for this population.


2014 ◽  
Vol 32 (22) ◽  
pp. 2344-2350 ◽  
Author(s):  
Gita Suneja ◽  
Meredith S. Shiels ◽  
Rory Angulo ◽  
Glenn E. Copeland ◽  
Lou Gonsalves ◽  
...  

Purpose HIV-infected individuals with cancer have worse survival rates compared with their HIV-uninfected counterparts. One explanation may be differing cancer treatment; however, few studies have examined this. Patients and Methods We used HIV and cancer registry data from Connecticut, Michigan, and Texas to study adults diagnosed with non-Hodgkin's lymphoma, Hodgkin's lymphoma, or cervical, lung, anal, prostate, colorectal, or breast cancers from 1996 to 2010. We used logistic regression to examine associations between HIV status and cancer treatment, adjusted for cancer stage and demographic covariates. For a subset of local-stage cancers, we used logistic regression to assess the relationship between HIV status and standard treatment modality. We identified predictors of cancer treatment among individuals with both HIV and cancer. Results We evaluated 3,045 HIV-infected patients with cancer and 1,087,648 patients with cancer without HIV infection. A significantly higher proportion of HIV-infected individuals did not receive cancer treatment for diffuse large B-cell lymphoma (DLBCL; adjusted odds ratio [aOR], 1.67; 95% CI, 1.41 to 1.99), lung cancer (aOR, 2.18; 95% CI, 1.80 to 2.64), Hodgkin's lymphoma (aOR, 1.77; 95% CI, 1.33 to 2.37), prostate cancer (aOR, 1.79; 95% CI, 1.31 to 2.46), and colorectal cancer (aOR, 2.27; 95% CI, 1.38 to 3.72). HIV infection was associated with a lack of standard treatment modality for local-stage DLBCL (aOR, 2.02; 95% CI, 1.50 to 2.72), non–small-cell lung cancer (aOR, 2.43; 95% CI, 1.46 to 4.03), and colon cancer (aOR, 4.77; 95% CI, 1.76 to 12.96). Among HIV-infected individuals, factors independently associated with lack of cancer treatment included low CD4 count, male sex with injection drug use as mode of HIV exposure, age 45 to 64 years, black race, and distant or unknown cancer stage. Conclusion HIV-infected individuals are less likely to receive treatment for some cancers than uninfected people, which may affect survival rates.


ESC CardioMed ◽  
2018 ◽  
pp. 1151-1153
Author(s):  
John Groarke

Cardio-oncology is a new and burgeoning field in cardiology focused on the cardiovascular (CV) health of patients with cancer. An increase in cases of cancer is projected across all age-groups and sexes in coming decades. Fortunately, as a result of earlier detection and better cancer treatments, the average overall 5-year survival for all invasive cancers has significantly improved in recent years. These factors contribute to a growing population of cancer survivors, which currently exceeds 15 million survivors in the United States alone. CV disease is now recognized as a major cause of morbidity and mortality among cancer survivors, and indeed competes with cancer as a leading cause of death in this population. CV care of patients before, during, and after cancer treatment presents unique challenges that will be explored in this section.


2017 ◽  
Vol 35 (5_suppl) ◽  
pp. 164-164
Author(s):  
Brittany Kimball ◽  
Gladys Asiedu ◽  
Carrie A. Thompson

164 Background: Adolescent and young adult (AYA) cancer survivors have distinctive and often unmet needs, may lead long lives after treatment, and are a population for whom targeted health supports are limited. Exercise in particular has become increasingly recognized as a vital part of cancer survivors’ health needs, yet, little is known about what interventions would be most appropriate for this population. This ongoing study reports early data on barriers and facilitators to exercise in AYA lymphoma survivors. Methods: We conducted a focus group with five young adult lymphoma survivors. Participants completed questionnaires to assess quality of life, exercise habits, and knowledge about evidence for exercise after cancer treatment. Charts were abstracted for demographic and treatment-related details. The focus group was audio recorded and transcribed. Data is being analyzed thematically to generate applied findings and identify areas for action. Results: Participants were 24-35 years old, 60% male, and an average of 2.97 years from the time of diagnosis. All reported some form of physical activity, with 80% active and 20% moderately active. Preliminary analysis identified fatigue, weight gain, and lack of time as barriers to exercise. Participants identified fatigue particularly in the early survivorship period, and discussed the issue of non-cancer survivor peers not relating with or recognizing fatigue after treatment. 100% of participants reported that someone from their doctor’s office had talked with them about exercise, but indicated during the focus group that this recommendation did not motivate them to exercise. Other themes revolve around the relationship between healthy diet and physical activity. In terms of an intervention, survivors were interested in activity trackers and fitness apps, exercise variety, and fitness groups targeted specifically for AYA survivors. Conclusions: Fatigue, weight gain, and time are barriers to exercise for AYA survivors. Interventions that incorporate fitness tracking technology, provide variety, and/or include other AYA survivors may be successful in this unique population.


2019 ◽  
Vol 8 (3) ◽  
pp. 335-341 ◽  
Author(s):  
Leena Nahata ◽  
Taylor L. Morgan ◽  
Amanda C. Ferrante ◽  
Nicole M. Caltabellotta ◽  
Nicholas D. Yeager ◽  
...  

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