Potential risk of residential asbestos exposure: Japanese general screening study for asbestos-related diseases (JGSARD).

e12541 Background: Currently, an argument about health risks by residential asbestos exposure as well as occupational asbestos exposure has been closed up in Japan. Therefore, the latest large-scale CT screening study reflective of a country's general situation of asbestos exposure will help citizens understand significant information about asbestos-related diseases. Methods: JGSARD is a prospective cohort study for the general population representative of Japan designed to evaluate the actual situation of asbestos exposure and the prevalence of asbestos-related diseases through chest radiography and low-dose CT (LDCT) at baseline and after 2 years of follow-up. From 2006 to 2008, 9810 subjects (mean age, 57 years; 54% male and 50% smokers) underwent baseline screening at 26 institutions in Japan. Lifetime self-reported history of asbestos exposure (SHAE) was obtained. Results: Occupational SHAE was definite and possible in 1103 (11.2%) and 1702 (17.3%) subjects, respectively, whereas residential SHAE was definite and possible in 262 (2.7%) and 931 (9.5%) subjects, respectively, although asbestos factory in their residential areas actually existed in 2870 (29.3%) subjects. The false negative rates of residential SHAE in all participants of this study (n=9810), those with pleural plaque on LDCT (n=264), and those with pleural plaque without occupational SHAE (n=83) were calculated as high value of 85.6%, 76.0%, and 87.9%, respectively. Presence of pleural plaque was significantly correlated with male (odds ratio [OR], 2.32), age 60 years and older (OR, 1.75), smoking (OR, 1.60), occupational or residential SHAE (OR, 3.92), residential period in asbestos factory area (OR every 10 years, 1.13), and asbestos-related work period (7 works identified). Lung cancer was identified in 29 (0.3%) subjects. Presence of lung cancer was significantly correlated with age 60 years and older (OR, 2.67) and presence of pleural plaque (OR, 4.17) regardless of occupational and residential SHAE. Conclusions: Our results indicate the potential risk of residential asbestos exposure and thus the importance of public relations and enlightenment for them among Japanese general population.

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Potential risk of asbestos exposure among Japanese general population: Japanese general screening study for asbestos-related diseases (JGSARD).

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.15_suppl.1530 ◽

2012 ◽

Vol 30 (15_suppl) ◽

pp. 1530-1530 ◽

Cited By ~ 1

Author(s):

Nobuhiko Seki ◽

Takuhiro Yamaguchi ◽

Kenji Eguchi ◽

Masahiro Kaneko ◽

Masahiko Kusumoto ◽

...

Keyword(s):

Lung Cancer ◽

General Population ◽

Potential Risk ◽

Low Dose ◽

Asbestos Exposure ◽

Low Dose Ct ◽

Pleural Plaque ◽

Pleural Plaques ◽

History Of ◽

Japanese General Population

1530 Background: The number of patients with pleural mesothelioma and lung cancer associated with asbestos exposure has recently been increasing in Japan. The aim of this study was to evaluate the results of screening for asbestos-related diseases in a group of Japanese general population. Methods: This prospective study was approved by the institutional review board. From 2006 to 2008, 9810 subjects (5283 men and 4527 women; mean age, 57 years) underwent chest radiography and low-dose CT examinations in 26 institutions in Japan. Among them, 6286 (64.1%) subjects underwent subsequent CT examinations after 2 years of interval. Clinical information such as histories of smoking and asbestos exposure was reviewed. Images were interpreted independently by 15 experienced pulmonologists or chest radiologists. Results: The history of asbestos exposure was definitely present in 1253 (12.8%) subjects, possibly present in 2058 (21.0%), and absent in 6499 (66.2%). On chest radiograph, pleural plaque and thickening were seen in 61 (0.6%) and 65 (0.6%) subjects, respectively. On low-dose CT, pleural plaque and thickening were identified in 264 (2.7%) and 245 (2.5%) subjects, respectively, and non-calcified pulmonary nodule/mass was seen in 1003 (10.2%). Furthermore, lung cancer was identified in 29 (0.3%) subjects. The history of asbestos exposure was not confirmed in 77 out of 264 subjects (29.2%) having pleural plaques on low-dose CT. Based on the logistic regression analysis, pleural plaque on low-dose CT was significantly correlated with male, age more than 60 years, smoking, and a history of asbestos exposure. Especially, total residential period in asbestos factory area as well as asbestos exposure work period showed significantly increased relative risk every 10 years. Similarly, lung cancer was significantly correlated with age more than 60 years, a history of asbestos exposure, and presence of pleural plaques. Conclusions: Our results indicate the presence of pleural plaques on low-dose CT among Japanese general population is closely associated with potential risk of asbestos exposure. However, about 30% of such subjects are not aware of a history of asbestos exposure.

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Potential Risk of Asbestos Exposure Among Japanese General Population: Japanese General Screening Study for Asbestos-Related Diseases (JGSARD)

Annals of Oncology ◽

10.1093/annonc/mds412 ◽

2012 ◽

Vol 23 ◽

pp. ix469

Author(s):

N. Seki ◽

K. Eguchi ◽

M. Kusumoto ◽

M. Kaneko ◽

T. Yamaguchi ◽

...

Keyword(s):

General Population ◽

Potential Risk ◽

Asbestos Exposure ◽

Screening Study ◽

Japanese General Population

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Lung cancer screening study spurs optimism, caution

PsycEXTRA Dataset ◽

10.1037/e458552008-001 ◽

2006 ◽

Author(s):

Carmen Phillips

Keyword(s):

Lung Cancer ◽

Cancer Screening ◽

Lung Cancer Screening ◽

Screening Study

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Assessment of knowledge of oral health hygiene among coastal guards in the port trust of south Tamil Nadu - A public health awareness survey

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl3.3560 ◽

2020 ◽

Vol 11 (SPL3) ◽

pp. 1861-1868

Author(s):

Bianca Princeton ◽

Abilasha R ◽

Preetha S

Keyword(s):

Lung Cancer ◽

Oral Health ◽

Oral Hygiene ◽

Tamil Nadu ◽

Asbestos Exposure ◽

The Other ◽

Oral Manifestations ◽

Illegal Activities ◽

The Right ◽

Oral Hygiene Habits

Oral hygiene is defined as the practice of keeping the mouth clean and healthy, by brushing and flossing to prevent the occurrence of any gum diseases like periodontitis or gingivitis. The main aim of oral health hygiene is to prevent the buildup of plaque, which is defined as a sticky film of bacteria and food formed on the teeth. The coastal guard is an official who is employed to watch the sea near a coast for ships that are in danger or involved with illegal activities. Coastal guards have high possibilities of being affected by mesothelioma or lung cancer due to asbestos exposure. So, a questionnaire consisting of 20 questions was created and circulated among a hundred participants who were coastal guards, through Google forms. The responses were recorded and tabulated in the form of bar graphs. Out of a hundred participants, 52.4% were not aware of the fact that coastal guards have high chances of developing lung cancer and Mesothelioma. 53.7% were aware of the other oral manifestations of lung cancer other than bleeding gums. Majority of the coastal guards feel that they are given enough information about dental hygiene protocols. Hence, to conclude, oral hygiene habits have to be elaborated using various tools in the right manner to ensure better health of teeth and gums.

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LUNGRADS AND UPDATE OF LUNG NODULES SCREENING BY LOW DOSE COMPUTED TOMOGRAPHY

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2015.4_5.2 ◽

2015 ◽

pp. 12-19

Author(s):

Thi Ngoc Ha Hoang ◽

Trong Khoan Le

Keyword(s):

Lung Cancer ◽

Low Dose ◽

False Negative ◽

Lung Nodule ◽

Lung Cancer Mortality ◽

Smoking History ◽

Low Dose Ct ◽

History Of ◽

Chest X Ray ◽

Low Dose Computed Tomography

Background: A pulmonary nodule is defined as a rounded or irregular opacity, well or poorly defined, measuring up to 3 cm in diameter. Early detection the malignancy of nodules has a significant role in decreasing the mortality, increasing the survival time and consider as early diagnosis lung cancer. The main risk factors are those of current or former smokers, aged 55 to 74 years with a smoking history of at least 1 pack-day. Low dose CT: screening individuals with high risk of lung cancer by low dose CT scans could reduce lung cancer mortality by 20 percent compared to chest X-ray. Radiation dose has to maximum reduced but respect the rule of ALARA (As Low as Resonably Archivable). LungRADS 2014: Classification of American College of Radiology, LungRADS, is a newly application but showed many advantages in comparison with others classification such as increasing positive predict value (PPV), no result of false negative and cost effectiveness. Key words: LungRADS, screening lung nodule, low dose CT, lung cancer

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