A multinational assessment of gastric and esophageal cancer burden by age, gender, and disease characteristics.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 29-29
Author(s):  
Kimberly A Lowe ◽  
Aaron Katz ◽  
Michael A. Kelsh ◽  
Thomas L. Vaughan
Keyword(s):  
Gastric Cancer ◽  
Esophageal Cancer ◽  
Cancer Incidence ◽  
Case Fatality ◽  
Incidence Rates ◽  
Males And Females ◽  
And Gender ◽  
Cancer Incidence Rates ◽  
The U.S ◽  
Country Specific

29 Background: Gastric and esophageal cancers are the fourth and eighth most common cancers worldwide, with an estimated 1.5 million new cases combined in 2008. A comprehensive, international comparison of the descriptive epidemiology of these diseases is lacking. The objectives of this study are to (1) characterize the current and projected incidence rates and the current case fatality of these cancer types by age and gender within countries in Europe, Asia, the Americas, Oceania, and Africa; (2) describe the temporal variation in cardia and non-cardia gastric cancer and squamous and adenocarcinoma esophageal cancer in the U.S. by age and gender. Methods: Data from GLOBOCAN were used to calculate country-specific incidence rates (per 100,000) for 2012, 2015, and 2025, and the country-specific case fatality (%) in 2012. Data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program in the U.S. were used to estimate gastric cancer incidence rates from 2004-2011 (per 100,000) and 12-month survival (%) stratified by gender, age (0-64/65+), stage at diagnosis, gastric cancer subtype, and esophageal cancer histology. Joinpoint regression was used to quantify changes in the Average Annual Percent Change (AAPC) in these outcomes. Results: GLOBOCAN results showed wide geographic variation in gastric and esophageal cancer incidence rates. In most countries, the case-fatality among males and females 65+ years was > 60%. In the U.S., the annual incidence of all gastric cancer subtypes decreased significantly among males and females 65+ (AAPC= -2.4% & -1.6%, respectively). Esophageal cancer incidence decreased in both genders and age groups, with a significant decline observed among females 65+ with squamous histology (-3.5%). Twelve-month survival in esophageal cancer showed modest improvements, with a significant increase observed among males 65+ with adenocarcinoma histology (2.0%). Conclusions: The worldwide burden of gastric and esophageal cancers is substantial. In the U.S., declines in incidence and modest improvements in survival of these cancers were observed.

Abstract A113: Regional variations in esophageal cancer incidence rates by census region in the United States, 1999-2008

2012 ◽  
Vol 5 (11 Supplement) ◽  
pp. A113-A113
Author(s):  
Jennifer Drahos ◽  
Manxia Wu ◽  
William F. Anderson ◽  
Katrina F. Trivers ◽  
Jessica King ◽  
...  
Keyword(s):  
United States ◽  
Esophageal Cancer ◽  
Cancer Incidence ◽  
The United States ◽  
Incidence Rates ◽  
Regional Variations ◽  
Cancer Incidence Rates

scholarly journals Modeling of Influential Predictors of Gastric Cancer Incidence Rates in Golestan Province, North Iran

2014 ◽  
Vol 15 (3) ◽  
pp. 1111-1117 ◽  
Author(s):  
Nasser Behnampour ◽  
Ebrahim Hajizadeh ◽  
Farid Zayeri ◽  
Shahriar Semnani
Keyword(s):  
Gastric Cancer ◽  
Cancer Incidence ◽  
Incidence Rates ◽  
Golestan Province ◽  
Cancer Incidence Rates

Predicting future cancer incidence by age and gender.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 1559-1559 ◽  
Author(s):  
Wesley B. Garner ◽  
Benjamin D. Smith ◽  
Jacob Ezra Shabason ◽  
Grant Richard Williams ◽  
Michelle Y. Martin ◽  
...  
Keyword(s):  
Older Adults ◽  
Cancer Incidence ◽  
The United States ◽  
Incidence Rates ◽  
Population Projections ◽  
Age And Gender ◽  
Total Cancer ◽  
And Gender ◽  
The Impact ◽  
Cancer Incidence Rates

1559 Background: Cancer remains a substantial and unique burden on society. While the impact of changing demographics on cancer incidence has previously been characterized (Smith et al, JCO, 2009), this has not been done with updated population data. Our objective was to update projections on the number of new cancer diagnoses in the United States by age and gender through 2040. Methods: Population-based cancer incidence data were obtained using SEER 18 delay-adjusted data. Population estimates were made by age, race, and gender using the 2010 US Census data population projections to calculate future cancer incidence rates. Trends in age- adjusted incidence rates for 23 cancer types were calculated as previously described (Edwards et al, Cancer, 2014). Results: From 2020 to 2040 the projected total cancer incidence will increase by almost 30% from 1.86 million to 2.4 million. This increase is due to the projected increase in population growth, particularly in older individuals. The population of older adults will represent a growing proportion of total cancer diagnoses. Specifically, patients ≥65 years old will make up 69% of all new cancer diagnoses, while 13% of new diagnoses will be in patients ≥85 years old by 2040 (see Table). Cancer diagnoses in females are projected to rise 27%, while male cancer diagnoses are projected to increase by 32% from 2020 to 2040. The incidence rates for lung, colorectal, and prostate cancer are expected to decline, while those for thyroid, liver, melanoma and myeloma are expected to increase. Conclusions: The landscape of cancer care will continue to change over the next several decades. The burden of disease will remain substantial and will continue to disproportionately affect older adults. The growing proportion of older cancer patients and changes in site-specific cancer incidence rates remain of particular interest. These projections should help guide future health policy and research priorities. [Table: see text]

Is there an association between air pollution levels and lung cancer incidence?

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e13584-e13584
Author(s):  
Seema Patel ◽  
Anees B. Chagpar
Keyword(s):  
Lung Cancer ◽  
Air Pollution ◽  
Linear Regression ◽  
Cancer Incidence ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Specific Data ◽  
Pollution Levels ◽  
Cancer Incidence Rates ◽  
Country Specific

e13584 Background: PM2.5 particles are an indicator of air pollution levels associated with various respiratory illnesses. We sought to determine the association between air pollution levels and lung cancer incidence across different countries. Methods: Country-specific data for median PM2.5 levels and age-standardized lung cancer incidence rates (ASLCIR) were collected for the year 2016 from the World Health Organization and the Global Cancer Observatory, respectively. Country-specific data for median age and proportion of smokers were collected from the Central Intelligence Agency and Our World in Data, respectively. Statistical analyses were performed using SPSS Version 26.0. Results: Across 105 countries, the median PM2.5 level was 18 ug/m3 (range; 6-94 ug/m3). The WHO has set 10 ug/m3 as the upper limit for PM2.5 levels; 91 (86.7%) of countries had rates higher than this. The ASLCIR was surprisingly higher in countries with PM2.5 ≤ 10 ug/m3 (median 28.7 vs. 13.9 per 100,000 population, Pearson correlation coefficient -0.386, p < 0.001). Countries with PM2.5 levels ≤ 10 ug/m3 tended to have a higher GDP (median $55,709 vs. $5,931, p < 0.001), and an older population (median 41.5 vs. 30.4, p < 0.001); however, the proportion of population who smoked was no different in countries with low vs. high PM2.5 levels (20.3% vs. 22.5%, p = 0.847). Controlling for age, GDP, and proportion of the population who smoke in a multiple linear regression model, ASLCIR were not influenced by median PM2.5 (see linear regression table below, p = 0.888). Removing PM2.5 levels from the model did not significantly affect the model fit (R2= 0.749 in both models). Conclusions: These results demonstrate that air pollution levels do not significantly impact lung cancer incidence rates, which are more related to age, tobacco use, and GDP. [Table: see text]

scholarly journals Area-to-Area Poisson Kriging Analysis of Mapping of County-Level Esophageal Cancer Incidence Rates in Iran

2013 ◽  
Vol 14 (1) ◽  
pp. 11-13 ◽  
Author(s):  
Naeimeh Sadat Asmarian ◽  
Ahmad Ruzitalab ◽  
Kavousi Amir ◽  
Salehi Masoud ◽  
Behzad Mahaki
Keyword(s):  
Esophageal Cancer ◽  
Cancer Incidence ◽  
Incidence Rates ◽  
County Level ◽  
Cancer Incidence Rates ◽  
Kriging Analysis ◽  
Poisson Kriging
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