scholarly journals Deep learning analysis for automatic lung nodule detection.

2019 ◽  
Vol 5 (suppl) ◽  
pp. 27-27
Author(s):  
Xiaohua Liu

27 Background: The prevalence of lung cancer has been increased markedly in worldwide range with growing clinical significance, the quantitative and qualitative analysis on lung nodules has proven to be important for the early-detection of lung cancer as well as its treatment in clinical practice. However, lung lesion screening performed by radiologists can be very time-consuming and its accuracy varies depending on doctor’s individual experiences. In this study, we aim to build up a robust CAD system that automatically detects the lesion locations and quantitatively characterizes the detected lesions on CT images. Methods: Specifically, we employed the deep learning analysis for lesion detection in patients and performed image processing techniques to generate quantitative morphology features for assisting lesion diagnosis . The data collected includes 3956 lung CT series (slice thickness≤3mm) with multiple lung nodules from 15 Class-A hospitals in China , 1155 lung CT scan from Luna16 dataset as well as CT scans from Kaggle dataset (Data Science Bowl 2017). Lung nodule annotation was then performed by two experienced radiologists and further assessed by four senior associate chief physicians. The obtained CT images were randomly selected and split to construct training, validation and test dataset. After preprocessing, a pre-trained ResNet18 framework is transferred to develop a robust detection system to detect the possible lung lesion locations with corresponding probabilities. Results: The resulting detection system yields FROC of 0.4663, recall of 82.46%, precision of 36.06% for 5~30mm nodules. Each detected lesion was labeled by its bounding box and was then analyzed through image processing algorithm to generate diagnostic assisting features, including longest diameter, shortest diameter, volume, largest cross section area as well as its density type (calcify, solid, partial solid, and ground-glass opacity). Conclusions: The proposed CAD system offers a fast and convenient approach for assisting the diagnosis of lung nodule pathologies, and it is beneficial to relate our research to the current framework of lung cancer diagnosis.

The mortality rate is increasing among the growing population and one of the leading causes is lung cancer. Early diagnosis is required to decrease the number of deaths and increase the survival rate of lung cancer patients. With the advancements in the medical field and its technologies CAD system has played a significant role to detect the early symptoms in the patients which cannot be carried out manually without any error in it. CAD is detection system which has combined the machine learning algorithms with image processing using computer vision. In this research a novel approach to CAD system is presented to detect lung cancer using image processing techniques and classifying the detected nodules by CNN approach. The proposed method has taken CT scan image as input image and different image processing techniques such as histogram equalization, segmentation, morphological operations and feature extraction have been performed on it. A CNN based classifier is trained to classify the nodules as cancerous or non-cancerous. The performance of the system is evaluated in the terms of sensitivity, specificity and accuracy


2022 ◽  
Vol 2022 ◽  
pp. 1-12
Author(s):  
Wenfa Jiang ◽  
Ganhua Zeng ◽  
Shuo Wang ◽  
Xiaofeng Wu ◽  
Chenyang Xu

Lung cancer is one of the malignant tumors with the highest fatality rate and nearest to our lives. It poses a great threat to human health and it mainly occurs in smokers. In our country, with the acceleration of industrialization, environmental pollution, and population aging, the cancer burden of lung cancer is increasing day by day. In the diagnosis of lung cancer, Computed Tomography (CT) images are a fairly common visualization tool. CT images visualize all tissues based on the absorption of X-rays. The diseased parts of the lung are collectively referred to as pulmonary nodules, the shape of nodules is different, and the risk of cancer will vary with the shape of nodules. Computer-aided diagnosis (CAD) is a very suitable method to solve this problem because the computer vision model can quickly scan every part of the CT image of the same quality for analysis and will not be affected by fatigue and emotion. The latest advances in deep learning enable computer vision models to help doctors diagnose various diseases, and in some cases, models have shown greater competitiveness than doctors. Based on the opportunity of technological development, the application of computer vision in medical imaging diagnosis of diseases has important research significance and value. In this paper, we have used a deep learning-based model on CT images of lung cancer and verified its effectiveness in the timely and accurate prediction of lungs disease. The proposed model has three parts: (i) detection of lung nodules, (ii) False Positive Reduction of the detected nodules to filter out “false nodules,” and (iii) classification of benign and malignant lung nodules. Furthermore, different network structures and loss functions were designed and realized at different stages. Additionally, to fine-tune the proposed deep learning-based mode and improve its accuracy in the detection Lung Nodule Detection, Noudule-Net, which is a detection network structure that combines U-Net and RPN, is proposed. Experimental observations have verified that the proposed scheme has exceptionally improved the expected accuracy and precision ratio of the underlined disease.


2021 ◽  
pp. 1-13
Author(s):  
Malathi Murugesan ◽  
Kalaiselvi Kaliannan ◽  
Shankarlal Balraj ◽  
Kokila Singaram ◽  
Thenmalar Kaliannan ◽  
...  

Deep learning algorithms will be used to detect lung nodule anomalies at an earlier stage. The primary goal of this effort is to properly identify lung cancer, which is critical in preserving a person’s life. Lung cancer has been a source of concern for people all around the world for decades. Several researchers presented numerous issues and solutions for various stages of a computer-aided system for diagnosing lung cancer in its early stages, as well as information about lung cancer. Computer vision is one of the field of artificial intelligence this is a better way to detect and prevent the lung cancer. This study focuses on the stages involved in detecting lung tumor regions, namely pre-processing, segmentation, and classification models. An adaptive median filter is used in pre-processing to identify the noise. The work’s originality seeks to create a simple yet effective model for the rapid identification and U-net architecture based segmentation of lung nodules. This approach focuses on the identification and segmentation of lung cancer by detecting picture normalcy and abnormalities.


2021 ◽  
Author(s):  
Syeda Furruka Banu ◽  
Md. Mostafa Kamal Sarker ◽  
Mohamed Abdel-Nasser ◽  
Hatem A. Rashwan ◽  
Domenec Puig

Lung cancer is a dangerous non-communicable disease attacking both women and men and every year it causes thousands of deaths worldwide. Accurate lung nodule segmentation in computed tomography (CT) images can help detect lung cancer early. Since there are different locations and indistinguishable shapes of lung nodules in CT images, the accuracy of the existing automated lung nodule segmentation methods still needs further enhancements. In an attempt towards overcoming the above-mentioned challenges, this paper presents WEU-Net; an end-to-end encoder-decoder deep learning approach to accurately segment lung nodules in CT images. Specifically, we use a U-Net network as a baseline and propose a weight excitation (WE) mechanism to encourage the deep learning network to learn lung nodule-relevant contextual features during the training stage. WEU-Net was trained and validated on a publicly available CT images dataset called LIDC-IDRI. The experimental results demonstrated that WEU-Net achieved a Dice score of 82.83% and a Jaccard similarity coefficient of 70.55%.


Mathematics ◽  
2021 ◽  
Vol 9 (13) ◽  
pp. 1457
Author(s):  
Muazzam Maqsood ◽  
Sadaf Yasmin ◽  
Irfan Mehmood ◽  
Maryam Bukhari ◽  
Mucheol Kim

A typical growth of cells inside tissue is normally known as a nodular entity. Lung nodule segmentation from computed tomography (CT) images becomes crucial for early lung cancer diagnosis. An issue that pertains to the segmentation of lung nodules is homogenous modular variants. The resemblance among nodules as well as among neighboring regions is very challenging to deal with. Here, we propose an end-to-end U-Net-based segmentation framework named DA-Net for efficient lung nodule segmentation. This method extracts rich features by integrating compactly and densely linked rich convolutional blocks merged with Atrous convolutions blocks to broaden the view of filters without dropping loss and coverage data. We first extract the lung’s ROI images from the whole CT scan slices using standard image processing operations and k-means clustering. This reduces the search space of the model to only lungs where the nodules are present instead of the whole CT scan slice. The evaluation of the suggested model was performed through utilizing the LIDC-IDRI dataset. According to the results, we found that DA-Net showed good performance, achieving an 81% Dice score value and 71.6% IOU score.


2020 ◽  
Vol 56 ◽  
pp. 101659 ◽  
Author(s):  
Chung-Feng Jeffrey Kuo ◽  
Chang-Chiun Huang ◽  
Jing-Jhong Siao ◽  
Chia-Wen Hsieh ◽  
Vu Quang Huy ◽  
...  

Lung cancer is a serious illness which leads to increased mortality rate globally. The identification of lung cancer at the beginning stage is the probable method of improving the survival rate of the patients. Generally, Computed Tomography (CT) scan is applied for finding the location of the tumor and determines the stage of cancer. Existing works has presented an effective diagnosis classification model for CT lung images. This paper designs an effective diagnosis and classification model for CT lung images. The presented model involves different stages namely pre-processing, segmentation, feature extraction and classification. The initial stage includes an adaptive histogram based equalization (AHE) model for image enhancement and bilateral filtering (BF) model for noise removal. The pre-processed images are fed into the second stage of watershed segmentation model for effectively segment the images. Then, a deep learning based Xception model is applied for prominent feature extraction and the classification takes place by the use of logistic regression (LR) classifier. A comprehensive simulation is carried out to ensure the effective classification of the lung CT images using a benchmark dataset. The outcome implied the outstanding performance of the presented model on the applied test images.


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