Differences in C-Reactive Protein (CRP) between depression levels in ischaemic stroke patients

2018 ◽  
pp. 81-85
Author(s):  
S.N. Lubis ◽  
W.H. Lubis ◽  
I. Nasution
2014 ◽  
Vol 30 (1) ◽  
pp. 45-49
Author(s):  
Kazi Giasuddin Ahmed ◽  
Abu Saleh Md Badrul Hasan ◽  
Biplop Kumar Roy ◽  
Md Rafiqul Islam ◽  
Md Ruhul Quddus

Background: Stroke is a dreadful health hazard all over the world as well as in our country. The relationship between serum C-reactive protein (CRP) level and acute ischaemic stroke is not well studied especially in Bangladesh. Aims and Objectives: To evaluate the association of C-reactive protein (CRP) in acute ischemic stroke .Materials and Methods: This case-control study was carried out in the Department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period from January 2006 to December 2007. A total of 30 acute ischaemic stroke patients were included in the case group. Another 30 age and sex matched and apparently healthy persons without any stroke were taken as controls. Results: The stroke patients [21 (70.0%) male; mean age, 56.3 (SD±13.7) years] and control subjects [25 (83.3%) male; mean age, 53.4 (SD ± 9.9) years] were similar in age and sex (p>0.05 each). CRP level was significantly higher in acute ischaemic stroke patients than that of control [42.06 (SD ± 21.26) mg/L; vs 4.30 (SD ± 0.072) mg/L; p<0.001]. CRP was found positive in 28 (93.7%) stroke patients and none of the control subjects. CRP was 16 times significantly higher in stroke patients than that of control subjects (OR=16.00; 95% CI=4.18-61.22; p<0.001).Conclusion: This study confirms that CRP is elevated in acute ischaemic stroke. More local studies are required regarding the significance of CRP as a risk factor for acute ischemic stroke. Bangladesh Journal of Neuroscience 2014; Vol. 30 (1): 45-49


2014 ◽  
Vol 15 (1) ◽  
pp. 41-47
Author(s):  
Md Robed Amin ◽  
Hanif Mohammad ◽  
Kazi Gias Uddin Ahmed ◽  
Devendra Nath Sarkar

Objectives: This aim of the study was to evaluate CRP and the risk factors in ischaemic stroke. Methods: This case control study was carried out from January 2006 to December 2007 in the department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in all the OPD and admitted stroke patients meeting the inclusion and exclusion criteria. Results: Out of 30 patients with ischaemic stroke 28(93.3%) patients had positive C-reactive protein value. 37% stroke patients were smoker. Mean total cholesterol, triglyceride and LDL level were higher and mean HDL level was lower among stroke patients in comparison to controls. 17% of stroke patients were suffering from diabetes mellitus & 80% of stroke patients were hypertensive. Conclusion: C-reactive protein is elevated in the acute phase of ischa emic stroke and could present a prognostic marker.DOI: http://dx.doi.org/10.3329/jom.v15i1.19859 J Medicine 2014; 15: 41-47


2011 ◽  
Vol 259 (2) ◽  
pp. 400-400 ◽  
Author(s):  
Heidi Ormstad ◽  
Hans Christian Dalsbotten Aass ◽  
Niels Lund-Sørensen ◽  
Karl-Friedrich Amthor ◽  
Leif Sandvik

2016 ◽  
Vol 42 (1-2) ◽  
pp. 32-40 ◽  
Author(s):  
Thomas Huber ◽  
Justus F. Kleine ◽  
Johannes Kaesmacher ◽  
Stefanie Bette ◽  
Holger Poppert ◽  
...  

Purpose: Despite the recent success of mechanical thrombectomy (MT) in the treatment of acute ischemic stroke, prognostic parameters and criteria for patient selection are yet uncertain. Elevated levels of white blood cells (WBCs) constitute an independent risk factor for unfavorable outcome. Here we studied the link between outcome and WBC counts obtained before and after successful MT. Methods: One hundred fifteen acute stroke patients successfully treated with MT (thrombolysis in cerebral infarction-scores 2b or 3) were included. WBC counts and C-reactive protein (CRP) levels were obtained prior to (WBC-pre, CRP-pre) and 1 day after MT (WBC-post, CRP-post). Clinical outcome measures consisted of National Institute of Health Stroke Scale (NIHSS) scores, and modified Rankin Scale (mRS) on day 90 (mRS-d90), dichotomized between scores ≤5 and >5 (NIHSS) and ≤2 and >2 (mRS). The association between WBC-/CRP-levels and outcome was assessed by correlation- and receiver-operating characteristic analyses. Results: WBC counts on day 1 after MT correlated significantly with NIHSS scores at discharge and mRS-d90. Among patients >50 years, no patient with WBC-post counts exceeding 14.2 G/l had favorable NIHSS scores (≤5), and no one with WBC-post counts ≥12.6 G/l had favorable mRS-d90 outcome-scores (≤2). Further, even WBC-pre counts ≥10.6 G/l predicted unfavorable mRS-d90-scores in this subgroup. Conclusion: Elevated WBC counts obtained in routine blood tests may constitute a simple and economic parameter to estimate outcome after successful MT. Moreover, present data suggest that in patients older than 50 years, WBC counts may help to predict outcome even when obtained prior to MT.


2019 ◽  
Vol 39 (2) ◽  
Author(s):  
Bo Yu ◽  
Ping Yang ◽  
Xuebi Xu ◽  
Lufei Shao

Abstract Studies on the association of C-reactive protein (CRP) with all-cause mortality in acute ischemic stroke patients have yielded conflicting results. The objective of this meta-analysis was to evaluate the prognostic value of CRP elevation in predicting all-cause mortality amongst patients with acute ischemic stroke. We searched the original observational studies that evaluated the association of CRP elevation with all-cause mortality in patients with acute ischemic stroke using PubMed and Embase databases until 20 January 2018. Pooled multivariate-adjusted hazard ratio (HR) with 95% confidence intervals (CI) of all-cause mortality was obtained for the highest compared with the lowest CRP level or per unit increment CRP level. A total of 3604 patients with acute ischemic stroke from eight studies were identified. Acute ischemic stroke patients with the highest CRP level were independently associated with an increased risk of all-cause mortality (HR: 2.07; 95% CI: 1.60–2.68) compared with the lowest CRP category. The pooled HR of all-cause mortality was 2.40 (95% CI: 1.10–5.21) for per unit increase in log-transformed CRP. Elevated circulating CRP level is associated with the increased risk of all-cause mortality in acute ischemic stroke patients. This meta-analysis supports the routine use of CRP for the death risk stratification in such patients.


Sign in / Sign up

Export Citation Format

Share Document