Risk of Exposure to and Mitigation of Effects of Aflatoxin on Human Health

Author(s):  
Sara Henry ◽  
Kitty Cardwell
2020 ◽  
Author(s):  
Guimei Yu ◽  
Jiu Wang ◽  
Lei Liu ◽  
Yun Li ◽  
Yi Zhang ◽  
...  

Abstract Background:Nitrate is one of the most common chemical contaminants of groundwater, and it is an important unqualified factor of rural groundwater in Yantai. In order to assess the risk of exposure to drinking water nitrate for adults and juveniles, in recent years, we monitored the nitrate concentrations in rural drinking water,a model was also used to assess the human health risk of nitrate pollution in groundwater. Methods: From the year 2015 to 2018, the drinking water in rural areas of Yantai was tested according to the "Sanitary Standard for Drinking Water" (GB5749-2006). The principal component analysis was used to analyze the relationship between groundwater chemicals and nitrate. The model was used to assess human health risks of groundwater nitrate through the drinking water and skin contact. Results: A total of 2348 samples were tested during the year 2015-2018.Nitrate and total dissolved solids, total hardness, chloride are all relevant, the above indicators may come from the same source of pollution; The median nitrate content (CEXP50) was 17.8 mg / L; the risk of exposure in each group was ranked as: Juveniles > Adult female > Adult male;the median health risk (HQ50) for minors and adults exceed 1. Conclusions:The concentrations of nitrate is stable and does not change over time.The high concentration of nitrate in rural areas of Yantai may be the result of the interaction of fertilizers and geological factors. The risk of exposure to nitrate in juveniles and adults is above the limit, so it is necessary to be on the alert for the high levels of nitrate.


2020 ◽  
Author(s):  
Guimei Yu ◽  
Song song Wang ◽  
Jiu Wang ◽  
Lei Liu ◽  
Yun Li ◽  
...  

Abstract Background: Nitrate is one of the most common chemical contaminants of groundwater, and it is an important unqualified factor of rural groundwater in Yantai. In order to assess the risk of exposure to drinking water nitrate for adults and juveniles, in recent years, we monitored the nitrate concentrations in rural drinking water, the HHRA model was also used to assess the human health risk of nitrate pollution in groundwater. Methods : From the year 2015 to 2018, the drinking water in rural areas of Yantai was tested according to the "Sanitary Standard for Drinking Water" (GB5749-2006). The principal component analysis was used to analyze the relationship between groundwater chemicals and nitrate. The HHRA model was used to assess human health risks of groundwater nitrate through the drinking water and skin contact. Results : A total of 2348 samples were tested during the year 2015-2018.Nitrate and total dissolved solids, total hardness, chloride are all relevant, the above indicators may come from the same source of pollution; The median nitrate content (C EXP50 ) was 17.8 mg / L; the C EXP95 was 53.4 mg / L; the risk of exposure in each group was ranked as: Juveniles > Adult female > Adult male;hazard quotient HQ 50 and HQ 95 for minors and adults exceed 1. Conclusions :The concentrations of nitrate is stable and does not change over time.The high concentration of nitrate in rural areas of Yantai may be the result of the interaction of fertilizers and geological factors. The risk of exposure to nitrate in juveniles and adults is above the limit, and HQ is over 1, so it is necessary to be on the alert for the high levels of nitrate.


2016 ◽  
Vol 23 (2) ◽  
pp. 347-356 ◽  
Author(s):  
Paulina A. Przybylińska ◽  
Mirosław Wyszkowski

Abstract The relevant literature was reviewed to identify phthalate sources in the environment and problems resulting from phthalate contamination of soil and water. Phthalate properties responsible for their toxicity for living organisms were identified, and the effects of phthalates on humans and animals were described. Special emphasis was placed on the effects of exposure to phthalates on human health. Phthalates are readily released into the environment and create a risk of exposure for humans and other living organisms. They are characterized by reproductive toxicity in humans and animals, they can cause infertility and reproductive problems in males. Phthalates are more toxic in young children, which are much more susceptible to phthalate exposure, including fetal life. Phthalates are used in numerous industries, and they are very difficult to eliminate from our daily surroundings.


2020 ◽  
Vol 11 (10) ◽  
pp. 8547-8559
Author(s):  
Hongjing Zhao ◽  
Yu Wang ◽  
Mengyao Mu ◽  
Menghao Guo ◽  
Hongxian Yu ◽  
...  

Antibiotics are used worldwide to treat diseases in humans and other animals; most of them and their secondary metabolites are discharged into the aquatic environment, posing a serious threat to human health.


2011 ◽  
Vol 81 (4) ◽  
pp. 238-239 ◽  
Author(s):  
Manfred Eggersdorfer ◽  
Paul Walter

Nutrition is important for human health in all stages of life - from conception to old age. Today we know much more about the molecular basis of nutrition. Most importantly, we have learnt that micronutrients, among other factors, interact with genes, and new science is increasingly providing more tools to clarify this interrelation between health and nutrition. Sufficient intake of vitamins is essential to achieve maximum health benefit. It is well established that in developing countries, millions of people still suffer from micronutrient deficiencies. However, it is far less recognized that we face micronutrient insufficiencies also in developed countries.


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