Micronutrient Deficiency and Immunity

Author(s):  
Sarah Cusick ◽  
Chandy John
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yong Eun Park ◽  
Soo Jung Park ◽  
Jae Jun Park ◽  
Jae Hee Cheon ◽  
TaeIl Kim ◽  
...  

Abstract Background Patients with inflammatory bowel disease (IBD) and intestinal Behçet’s disease (BD) are vulnerable to micronutrient deficiencies due to diarrhea-related gastrointestinal loss and poor dietary intake caused by disease-related anorexia. However, few studies have investigated the incidence and risk factors for micronutrient deficiency. Methods We retrospectively analyzed 205 patients with IBD who underwent micronutrient examination, including folate, vitamin B12, 25-OH-vitamin D, and/or ferritin level quantification, with follow-up blood tests conducted 6 months later. Results Eighty patients (39.0%), who were deficient in any of the four micronutrients, were classified as the deficiency group, and the remaining 125 (61.0%) were classified as the non-deficient group. Compared to those in the non-deficiency group, patients in the deficiency group were much younger, had more Crohn's disease (CD) patients, more patients with a history of bowel operation, and significantly less 5-amino salicylic acid usage. Multivariate analysis revealed that CD and bowel operation were significant independent factors associated with micronutrient deficiency. Conclusions The incidence of micronutrient deficiency was high (39.0%). Factors including CD, bowel operation, and younger ages were found to be associated with higher risks of deficiency. Therefore, patients with IBD, especially young patients with CD who have undergone bowel resection surgery, need more attention paid to micronutrition.


2012 ◽  
Vol 42 (5) ◽  
pp. 362-370 ◽  
Author(s):  
Ignasius Radix A. ◽  
Vellingiri Vadivel ◽  
Donatus Nohr ◽  
Hans Konrad Biesalski

Author(s):  
Marjoleine A. Dijkhuizen ◽  
Frank T. Wieringa ◽  
Clive E. West ◽  
Muhilal

Author(s):  
P. Ramamoorthy ◽  
P. Christy Nirmala Mary ◽  
P. Saravanapandian ◽  
A. Gurusamy ◽  
K. Kumutha

A soil resource inventory was conducted at village level in the Melur block of Madurai district, Tamil Nadu to assess the micronutrients status in the soils and to prepare fertility maps depicting the extent of soil micronutrient deficiency/sufficiency using GIS and GPS techniques. Soil samples were collected at revenue village wise along with geo coordinates and analysed for available micronutrients such as Zn, Fe, Cu and Mn by adopting standard procedures. Based on the nutrient status, the soils were grouped as deficient or sufficient using the critical limits. Per cent deficiency of micronutrients in Melur block was worked out and the thematic maps showing status of different available micronutrients were generated. The results indicated that, Fe and Zn  deficiency is most prevalent in the soils of Melur block  in Madurai district to an extent of more than 35 per cent, followed by Cu (1.1%) and Mn (10%).


Author(s):  
Harjot Kaur ◽  
Sanjay Piplani ◽  
Manas Madan ◽  
Mohit Paul ◽  
Saraswati G. Rao

<p><strong>Background:</strong> Untreated geriatric anemia is important to diagnose early as it is associated with greater morbidity and mortality in comparison to the anemia in younger adults.</p><p><strong>Objectives:</strong> To determine the prevalence, patterns of anaemia, and to assess haemopoietic nutrient status of geriatric population attending a hospital.</p><p><strong>Material and Methods:</strong> 2540 subjects aged 60 years and above, attending our geriatric clinic were screened for presence of anemia. 100 anemic subjects were randomly selected for further characterization. Tests carried out were, pattern of anemia, full blood count, serum ferritin and stool for occult blood. Vitamin B12, folate and other additional investigations were carried out in selected patients as per study protocol. Main outcome measure: Prevalence, pattern and underlying etiologies of anemia.</p><p><strong>Results:</strong> The prevalence of anemia was 71%. Normocytic blood picture was most common. Eleven cases had absolute iron deficiency. 5 and 2 cases had low vitamin B12 and folate levels respectively. Nine out of 11 (82%) patients with depleted iron stores had positive stool occult blood.</p><p><strong>Conclusions:</strong> Screening for anemia is important in all geriatric patients seeking medical care, irrespective of the presenting illness. Also a dedicated search for micronutrient deficiency and stool occult blood should be a routine component of the etiological work up of anemic elderly.</p>


2020 ◽  
pp. 192-200
Author(s):  
V. M. Kodentsova ◽  
D. V. Risnik

Multiple micronutrient deficiency (simultaneous insufficient supply of the organism with several vitamins at once (vitamin D, B group), as well as calcium, magnesium, zinc and iodine, and not an isolated deficiency of any one micronutrient is characteristic of a significant part of the Russian population throughout the year, regardless of places of residence. The growing need of the organism at different periods of life (puberty, pregnancy, breastfeeding, aging), various diseases, drug therapy, the period of convalescence, stress, the use of various diets, enrichment of the diet with polyunsaturated fatty acids and dietary fiber, religious observance, adverse environmental factors further increase the risk of multiple micronutrient deficiencies. Micronutrients (vitamins and essential minerals) are closely interconnected into complex metabolic networks, which provide maintaining homeostasis and health. Deficiency of each of the essential micronutrients is a risk factor for the development of a particular disease, and simultaneous multiple micronutrient deficiency creates a “causality network” of not just one, but several diseases at once. Conversely, an adequate or optimal sufficiency of the body with all micronutrients, respectively, creates a “network of conditions ensuring the prevention of the disease”, due to the full implementation of all processes dependent on them in the body. This means that replenishing inadequate food intake of scarce micronutrients is an important way to maintain health and longevity. Given the variety of vitamin-mineral supplements, it is important to choose the right supplement. The maximum effectiveness to maintain the body’s vitamin and mineral status at the optimum level will be ensured by the intake of not individual micronutrients, but vitamin and mineral supplements containing a complete set of vitamins in doses close to the physiological needs of the body and basic minerals (calcium, magnesium, zinc and iodine), the deficit of which is characteristic for the Russian population.


2021 ◽  
Vol 22 (1) ◽  
pp. 60-71
Author(s):  
I.A. Lapik ◽  
◽  
K.M. Gapparova ◽  
A.V. Galchenko ◽  
◽  
...  

Low caloric diet is used in the complex treatment of patients with diabetes mellitus and obesity. However, the reduced caloric food can inadvertently lead to decreased intake of micronutrients. The main goal of the research was to assess the necessity and effectiveness of the vitamin-mineral complex in the treatment of type 2 diabetes with obesity. Methods: 80 females suffering from type 2 diabetes and obesity, ranging from 40 to 65 years old participated in the study. The total patients were divided into two groups, each containing 40 patients. All patients were given a personalized diet and 1000mg of metformin every day. The experimental group, besides that, received vitamin-mineral complex. The biochemical analysis of the blood, composition of the body, and the complaint on micronutrient deficiency were taken before the experiment and after 14 days of the therapy. Results: Supplementation of the vitamin-mineral complex was associated with higher blood serum levels of vitamins B6, B12, B9, C, D, potassium, calcium, magnesium and zinc, and lower levels of glucose. Clinical manifestations, associated with micronutrient deficiency, were significantly decreased in patients who were given vitamin-mineral complex. All these changes were valid both in relation to the initial level in the study group and to the indicators after treatment in the control group. Conclusion: Micronutrient supplements may be a very important part of the combined therapy of patients with diabetes mellitus and obesity.


Author(s):  
A. Capone ◽  
A. S. Dario ◽  
M. Z. Menegon ◽  
R. R. Fidelis ◽  
H. B. Barros

<p class="Default">No cerrado brasileiro a deficiência de boro no solo ocorre com maior frequência. A cultura do girassol é muito sensível à deficiência deste micronutriente, além de apresentar pouca eficiência em seu aproveitamento. Neste contexto, objetivou-se com este estudo avaliar as respostas de cultivares de girassol a doses crescentes de boro no período da entressafra no cerrado tocantinense. O experimento foi conduzido em Gurupi, (TO), com sistema de plantio direto em sucessão a soja, sobre Latossolo Vermelho Amarelo distrófico. O delineamento experimental utilizado foi de blocos casualizados, com quinze tratamentos e quatro repetições. Os tratamentos foram dispostos num esquema fatorial simples 3 x 5, constituído por três cultivares de girassol (variedade Br 122, híbridos Aguará 4 e Helio 863) e cinco doses de ácido bórico (0, 1, 2, 3 e 4 kg ha<sup>-1</sup>). As características avaliadas foram: altura de planta, diâmetro da haste, diâmetro do capítulo, concentração de boro foliar, massa de mil aquênios e produtividade de aquênios. A dose de 3 kg ha<sup>-1</sup> de boro proporcionou, em sua grande maioria, as melhores respostas das cultivares Br 122, Aguará 4 e Helio 863 quanto às características avaliadas. No entanto, com esta dose, a cultivar Aguará 4 apresenta melhor aproveitamento para produção de aquênios.</p><p class="Default" align="center"><strong><em>Responses of sunflower cultivars to increasing doses of boron in the </em></strong><strong><em>between harvests the Cerrado Tocantinense</em></strong><strong><em></em></strong></p><p class="Default"><strong>Abstract</strong><strong>:</strong> In the brazilian cerrado soil boron deficiency occurs more frequently. The sunflower crop is very sensitive to this micronutrient deficiency, and have little efficiency in its use. In that context, aimed to of this study was to evaluate the response of sunflower cultivars to increasing doses of boron during the between harvests in the cerrado tocantinense. The experiment was conducted in Gurupi (TO), with no-tillages soybeans in succession on dystrophic Red Yellow Latosol. The experimental design was a randomized block design with fifteen treatments and four replications. The treatments were arranged in a factorial 3 x 5 simple, composed of three cultivars of sunflower (variety Br 122, hybrid Aguará 4 and Helio 863), and five doses of boric acid (0, 1, 2, 3, and 4 kg ha<sup>-1</sup>). The characteristics evaluated were: plant height, stem diameter, head diameter, leaf boron concentration, weight of thousand achenes and productivity achenes. The dose of 3 kg ha<sup>-1</sup> resulted boron, mostly, the best responses of the cultivars Br 122, Aguará 4 and Helio 863 on the characteristics evaluated. However, at this dose, the cultivar Aguará 4 has better use for achene production.</p><p class="Default"> </p>


2012 ◽  
pp. 333-342
Author(s):  
Frank T. Wieringa ◽  
Marjoleine A. Dijkhuizen ◽  
Jacques Berger

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