Diurnal rhythm of plasma delta-sleep-inducing peptide in humans: evidence for positive correlation with body temperature and negative correlation with rapid eye movement and slow wave sleep

1994 ◽  
Vol 78 (5) ◽  
pp. 1085-1089 ◽  
Author(s):  
T. C. Friedman
1995 ◽  
Vol 269 (1) ◽  
pp. R208-R214 ◽  
Author(s):  
H. Li ◽  
E. Satinoff

We examined the relationship between circadian rhythms of body temperature (CTR) and sleep in adult and old female rats. Body temperature was recorded telemetrically for months and sleep for 24 h in a 12:12-h light-dark cycle at 23 degrees C. Some old rats had robust CTRs (old good), and some had unstable or absent CTRs (old unstable). Old unstable rats had lower daily mean body temperatures, smaller daily amplitudes, and a more advanced CTR phase than adult rats and old good rats. Old good rats matched adult rats in all measures. In old good rats, circadian parameters of sleep were normal, whereas in old unstable rats the amplitudes of slow-wave and rapid eye movement sleep were decreased, although the amounts were equivalent. Rhythmic parameters of sleep correlate well with the stability or instability of the CTR, whereas homeostatic regulation of rapid eye movement and slow-wave sleep do not seem to be impaired during aging and are independent of the stability of the CTR.


1981 ◽  
Vol 241 (4) ◽  
pp. E269-E274
Author(s):  
J. E. Garcia-Arraras

Slow-wave sleep (SWS) and rapid-eye-movement sleep (REM) were recorded in cats for 32 h a) under control conditions, b) following intraventricular infusions of artificial cerebrospinal fluid (CSF), and c) following infusions of sleep-promoting factor S prepared from human urine (SPU). During the first 12 h after receiving artificial CSF, the cats slept 4.9 +/- 0.2 h in slow-wave sleep (SWS) and 1.4 +/- 0.1 h in REM. Similar values were obtained from the same cats under control conditions. After infusions of SPU, the duration of SWS in the same cats increased to an average of 6.9 +/- 0.5 h with no significant change in REM averaged over 12 h; a transient decrease of REM in the first 4 h was fully compensated in subsequent hours. The increased SWS induced by the sleep-promoting factor from human urine subsided after 12 h, and there was no compensatory increase in wakefulness during the subsequent 20 h. The normal sleep cycle was not affected. In cats, therefore, the primary effect of SPU is to increase normal SWS, with little effect on REM.


2009 ◽  
Vol 63 (2) ◽  
pp. 176-179
Author(s):  
Yu-San Chang ◽  
Chung-Yao Hsu ◽  
Shu-Hui Tang ◽  
Ching-Yu Lin ◽  
Ming-Chao Chen

1973 ◽  
Vol 4 (2) ◽  
pp. 201-212 ◽  
Author(s):  
Vincent P. Zarcone

Both marijuana and alcohol have effects on sleep which can be clinically important if either drug is used heavily. A number of polygraphic studies of both drugs' effect on sleep demonstrate that both are rapid eye movement (REM) sleep suppressors and that both effect the REM sleep deprivation response for days after the acute effects have ceased. Marijuana also increases slow wave sleep compared to alcohol which decreases it. The studies reviewed indicate that marijuana, like alcohol, has persisting effects on neuronal activity and presumably on its underlying neurochemical regulation. Also, the studies suggest that caution should be employed in advising the public about the use of marijuana.


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